Abstract
Child mortality, particularly among infants below 5 years, is a significant community well-being concern worldwide. The health sector’s top priority in emerging states is to minimize children’s death and enhance infant health. Despite a substantial decrease in worldwide deaths of children below 5 years, it remains a significant community well-being concern. Children under five years of age died at 37 per 1,000 live birth globally in 2020. However, in underdeveloped countries such as Pakistan and Ethiopia, the fatality rate of children per 1,000 live birth is 65.2 and 48.7, respectively, making it challenging to reduce. Predictive analytics approaches have become well-known for predicting future trends based on previous data and extracting meaningful patterns and connections between parameters in the healthcare industry. As a result, the objective of this study was to use data mining techniques to categorize and highlight the important causes of infant death. Datasets from the Pakistan Demographic Health Survey and the Ethiopian Demographic Health Survey revealed key characteristics in terms of factors that influence child mortality. A total of 12,654 and 12,869 records from both datasets were examined using the Bayesian network, tree (J-48), rule induction (PART), random forest, and multi-level perceptron techniques. On both datasets, various techniques were evaluated with the aforementioned classifiers. The best average accuracy of 97.8% was achieved by the best model, which forecasts the frequency of child deaths. This model can therefore estimate the mortality rates of children under five years in Ethiopia and Pakistan. Therefore, an online model to forecast child death based on our research is urgently needed and will be a useful intervention in healthcare.
1 Introduction
One of the most widely utilized markers of a kid’s well-being and health is child mortality. Every year, millions of children below the age of 5 years die worldwide, and this demise frequency could have been avoided. Even though the global death rate for children under 5 years of age has reduced, it remains a significant public health concern. In 2020, the global death rate for children under 5 years of age was 37 deaths per 1,000 births [1]. In 2020, fewer children under 5 years of age will die than in 1990, when they perished at 93 fatalities per 1,000 lb. The Sustainable Development Goal (SDG) for children under the age of 5 years is to lower the death rate of children under 5 years of age to at least 15 per 1,000 live births by 2030 [2].
There are variances between countries in terms of mortality reduction. Children under 5 years of age have declined significantly, from 216 deaths per 1,000 live births in 1950 to 37 deaths per 1,000 live births in 2020. Despite considerable reductions in worldwide under-five mortality, many countries have high death rates. They cannot reach MDG 4’s goal to “halve the under-five mortality rate between 1990 and 2020.”
Child mortality is a major problem in developing nations, particularly in those with middle-low incomes. Pakistan, a nation with a low health ranking, must give priority to reducing child mortality. According to the annual Human Development Index (HDI) published by the United Nations Development Program (UNDP, 2020), Pakistan is ranked 155th out of 189 countries. Pakistan has notably poor standards for children’s health. Pakistan is the third highest in the world in terms of baby, maternal, and fetal mortalities. The child mortality rate in Pakistan has reduced, from 112 deaths per 1,000 lb in 1990–1991 to 65 deaths per 1,000 lb in 2020–2021 [3]. As illustrated in Figure 1, the drop rate of mortality in Pakistan is slow as compared to that in Ethiopia.

Annual mortality rate of children under the age of 5 years in Pakistan, Ethiopia, and globally.
Despite numerous healthcare sector initiatives, Pakistan’s mortality rate for children under 5 years remains lower than that of developing countries such as Ethiopia. Ethiopia had a child death rate of 104 per 1,000 births in 2006, whereas Pakistan had 98 per 1,000 births; Ethiopia now has a significant drop-off. Ethiopia’s mortality rate fell to 48.7 from 104 in 2020. However, Pakistan has yet to attain the same percentage drop in mortality as Ethiopia. Pakistan’s death frequency dropped from 98 per 1,000 live births in 2006 to 65.7 in 2020. The rapid birth of children was seen during the pandemic, where underdeveloped countries suffered more deaths than developed countries due to a lack of proper nutrition and hunger. As a result, to reach SDG4, this study examined both the country’s health data and the predictors of child mortality.
The data from many Ethiopian and Pakistani demographic health surveys are now available online, showing a decrease in childhood mortality. As a result, there is a pressing need to study and implement cutting-edge approaches and technologies to help health experts and practitioners infer knowledge and other important information from enormous datasets [3]. Big data analytics is a growing field where data mining techniques uncover interesting patterns and relationships from massive databases. Many data mining methods are freely available for use in big data analytics, and they can answer issues that standard statistical tools have previously been unable to address.
Data mining methods find application in diverse fields such as financial forecasting, intrusion and fraud detection, criminal investigation, observation of students' learning patterns, and development of educational techniques. These techniques have gained widespread usage in areas including healthcare and bioinformatics, among others, for the purpose of analysis, detection, and forecasting. Data mining techniques can detect and uncover common and unique patterns in large datasets, find a correlation between variables, and construct a prediction model. To develop models, predictive analytics approaches extract patterns from complicated, heterogeneous, vast, noisy, and incomplete data.
The main goal of this venture is to use predictive analytics approaches to present a predictive model for below-five mortality in Pakistan. The study’s primary goal is to use the findings to inform and develop intervention tactics and national initiatives to lower the number of children under 5 years of age who die in the country. Similar research articles have been investigated to achieve this goal and to identify significant factors and interactions between factors that directly or indirectly affect child mortality in local country datasets. Numerous previous studies analyzed macro-level datasets from the Ethiopian Demographic Health Survey (EDHS), the Pakistan Demographic Health Survey (PDHS), and the Pakistan Social, Living, and Standards Measurement (PSLM) and discovered significant predictors of child mortality. Numerous analytic and prediction techniques were utilized in those investigations, including logistic regression (BLR), bivariate and multivariate analysis, maximum likelihood method (MLM), Tree (J-48), and Rule-based (PART). These studies assist in selecting high-priority locations for ongoing efforts to recover motherly health and child death. This study analyses past data and forecasts whether a child will die or live in the future using advanced data mining and machine learning techniques. These predictive methods differ from more established and widely used statistical data analysis methods, relying heavily on assumptions. They have resulted in developing an improved predictive model that assists policymakers and health professionals in making timely healthcare interventions to reduce under-five child mortality.
2 Literature review
There is a dire need to detect the factors behind children’s death in Pakistan to reduce child mortality. There are studies examining issues affecting children’s death in Pakistan. The socioeconomic characteristics of children who died in Pakistan are determined in ref. [4]. The previous research employed the PDHS 2014–2015 dataset and analyzed 8,297 records using BLR. In addition, correlated variables were converted using principal component analysis. This study reveals that there is no difference between male and female offspring mortality rates among children under the age of 5 years and explains why. According to the study, a child’s high birth weight, extended gestation period, larger family size, the mother’s asset ownership, education, and household decision-making reduce child mortality.
Another study [5] uses BLR analysis to find and categorize indicators that demonstrate communal, monetary, and ecological factors are connected with infant death in Pakistan. “Mother’s tutoring, previous birth break, family size, child’s birth weight, birth order, Area, and breastfeeding” are all original to be significant predictors of a child death under 5 years in Pakistan. Child mortality was researched compared to other areas and found to be higher in Baluchistan. This study also noted that child mortality was much lesser when the kid was breastfed on time than when the child was not breastfed. There were no advanced predictive analytics methods or methodologies applied. Previous research has only served to indicate critical areas for intervention and identify determinants through statistical analysis.
The previous study [6] clarifies the demographic, economic, environmental, and geographic factors contributing to Pakistan’s child mortality. The dataset Pakistan social living and standards measurement, which contains 14,540 children under 8 years of age and is categorized into rural and urban zones, was used. The majority of youngsters were diagnosed with diarrheal illness. Confident children suffer from respiratory infections. The factors contributing to morbidity were identified using linear regression and maximum likelihood approaches. Child mortality can be predicted using major indicators described in the literature.
According to a study published in ref. [7], essential drivers for the death of children under 5 years of age in Pakistan were explored. Pakistan was identified as one of the five countries with the maximum death rate child under 5 years of age. This study used P-D-H-S data gathered by the National Population Studies (N-I-P-S) to determine that kids under the age of 1 year die at a high rate in Pakistan. According to the study, social factors such as awareness, media exposure, and maternal education reduce child mortality. In Pakistan, affluence, mother qualification, and media disclosure are noteworthy predictors of child death. Binary logistics and the MLM were used to estimate econometric parameters, implying that data on local zones and their inhabitants are acute for developing operative strategies to address the issues.
A method for identifying characteristics and creating a web-based application for predicting under-five child mortality in the native Ethiopian language was provided in one study [8], utilizing classification data mining techniques. J48 using EDHS data, a decision tree technique, and a PART strategy for rule induction were employed to predict child fatalities. Using the Waikato Environment for Knowledge Analysis, the best models were built (WEKA). To find the dataset’s most pertinent health predictors, we used Fisher’s score. Logistic regressions and odds ratios were used in SPSS version 20.0 to identify risk factors for child mortality. The area under the receiver operating characteristics curve, sensitivity, accuracy, and specificity were used to validate the model. The developed prediction model could be used to support at least five ongoing child health programs in Ethiopia. This article proposes that novel categorization techniques generate perfect models. The developed web-based prediction model is just for Ethiopians, and it is critical to expand this web-based application to other widely spoken languages.
The study presented in ref. [9] built a predictive analytics system to precisely estimate death rates and pinpoint the major causes of excessive child mortality. According to our research, decision trees help locate the key classification rules relating to the causes of child fatalities, and the Nave Bayes classifier has the highest average accuracy in predicting the child fatality rate (96.4%).
Predictive analytics uses historical data to determine the likelihood of a future incident. It provides an idealized perspective on what is occurring and what should be done to ensure success. It delivers the most accurate future forecast through machine learning, mathematical models, and data. Data mining is an inventive technique when faced with a massive dataset that requires prediction, analysis, or pattern identification. Machine learning is a rapidly emerging topic in computer science, information technology, and health informatics. Machine learning’s primary goal is to develop algorithms on a labeled dataset that can learn, infer, and progress over time and be utilized for prediction and analytics. Numerous data mining techniques are widely employed in various industries, and the primary healthcare industry has benefited significantly from these techniques. It provides several risk management decision support tools to enhance healthcare quality and patient safety. The healthcare sectors face significant hurdles in critical areas such as data integration, computer-aided diagnosis, and disease prediction as they strive to cut healthcare costs. Machine learning suggests several tools and techniques, algorithms, and frameworks that address these issues. This article uses various widely used prediction methodologies and data mining tools.
3 Methodology
Following a study of the situation and with support from earlier research, the techniques are aimed to identify the critical elements that tip to the demise of children below the age of 5 years. This was accomplished by using two case studies utilizing the demographic health dataset of Ethiopia and the demographic health survey dataset of Pakistan; these studies were mutually used to determine the demographic determinant factors. The discovery of multiple roots of child death under the age of 5 years and the necessity of urgent intervention in the healthcare arena to reduce child mortality are noteworthy. Both case studies are given in detail in the following sections, along with the determinant elements that have been investigated in each case.
3.1 Case study EDHS dataset
The data from the 2019 EDHS is subjected to a variety of machine learning classifiers. This research study was carried out in Pakistan from November 2020 to April 2021. It took place between November 2020 and April 2021. The identical EDHS 2019 dataset was used in this study. The CSA initially obtained the documents in Ethiopia and the United States. The information was obtained from the MEASURE DHS database [8], freely available online. The EDHS is a cross-sectional survey typical of the entire country [3], and it gives a thorough picture of demographic, maternal, and child health outcomes. The 2019 EDHS report, publicly available on the Internet, contains information on the procedures used to collect the datasets (WWW). It was possible to recover a sample of 12,654 records that satisfied the criteria. The children’s dataset was created by extracting relevant socioeconomic and demographic elements from the dataset and naming them. The infant’s survival status, which is classified as either “alive” or “dead,” serves as the study’s outcome variable. Children of “alive” mothers stayed “alive” throughout the course of the study, but babies of “dead” mothers perished once or more.
3.1.1 Factors contributing to the death of children
The significant risk factors in this study include the paternal qualification, gender of a child, previous birth break, wealth index, family members, size of children at birth, birth order number, and breast milk availability. Table 1 presents the predictors used in the EDHS dataset.
Predictors of children’s death in Ethiopia
Predictors | Type (C/N) | Attributes value |
---|---|---|
Place of residence | Categorical | Urban |
Rural | ||
Breastfeeding | Categorical | No |
Yes | ||
Preceding birth interval | Numeric | — |
Parental education | Categorical | Not educated |
Primary pass | ||
Secondary pass | ||
Higher education | ||
Do not know | ||
Mother occupation | Categorical | Working |
Not working | ||
Mothers age | Numeric | — |
Maternal education | Categorical | Not educated |
Primary pass | ||
Secondary pass | ||
Technical/vocational | ||
Higher education | ||
DK | ||
Age of mother on FB | Numeric | — |
Presence of diarrhea | Categorical | Yes |
No | ||
Received family planning | Categorical | Yes |
No | ||
Sex of child | Categorical | Male |
Female |
3.2 PDHS dataset
The PDHS is a cross-sectional, nationally representative study [3] that assesses population, mother, and child health. The data from the 2020–2021 PDHS are used to train machine learning algorithms. It was performed in Pakistan from November 2017 to April 2018, with results published in April 2018. The PDHS 2020–2021 dataset was used in this study. A complete set of data was obtained from the MEASURE DHS database [8, which is freely accessible online]. The PDHS 2020–2021 annual report, published on the data originator’s web platform, includes data collection techniques details. The P-D-H-S used a two-stage model approach to select respondents for the study. Since sections of 12,912 homes were nominated and questioned, it was feasible to successfully interview 11,669 families in Ethiopia, excluding Gilgit Baltistan and Azad Jammu and Kashmir. Out of 1,792 households chosen, 1,597 families and 974 dwellings were cross-examined and questioned, according to the results of the Jammu and Kashmir survey.
The dataset was analyzed for pertinent socio-economic and demographic factors. The outcome variable in this study is the child’s persistent status, which is characterized as either living or dead. Alive mothers were those whose children were “alive” throughout the study, whereas the “dead” mothers were those whose infants died one or more times throughout the study.
3.2.1 Risk factors associated with children’s death
The key risk factors in this study include the mother’s qualification, area, previous birth break, wealth index, family counts, size of children at delivery, and breast milk availability. Table 2 represents the predictors used in the PDHS dataset.
Predictors of child mortality in Pakistan
Predictors | Type | Values |
---|---|---|
Region | Categorical | Punjab |
Sindh | ||
KPK | ||
Baluchistan | ||
GB | ||
ICT | ||
AJK | ||
FATA | ||
Mother education | Categorical | Not educated |
Primary | ||
Middle | ||
Secondary | ||
Higher | ||
Wealth index | Categorical | Poor |
Middle | ||
Richer | ||
Richest | ||
Family members | Numeric | — |
Preceding birth interval | Numeric | — |
Birth order number | Numeric | — |
Breastfeeding | Yes | |
No | ||
Size of children at birth | Categorical | Massive size |
Bigger than average | ||
Average | ||
I am not sure | ||
Smaller than the normal | ||
Very little |
3.3 Experimental plan and model building
In SPSS version 20, 12,000 data records with 9 attributes are imported into the dataset. Data are cleaned using preprocessing techniques by deleting duplicate records from the dataset. The lost values are ascribed using predictive mean matching (P-M-M), a popular technique for dealing with missing data. The property also includes categorical values encoded into numerical values, such as region, which has eight category values such as Punjab, Sindh, and others. As a result, we allocated unique values to each province, such as 0 for Punjab and 7 for Fata. The same procedure was used to change the other properties.
The WEKA 3.8 tool was fed the improved dataset. The refined dataset is divided into “alive” and “dead.” Moms with alive children are found in the alive clusters, while mothers with one or more deceased children are seen in the dead collections. Meanwhile, both subgroups’ data sizes are unbalanced. If the data are used as-is, the classifiers will not function well because there will be no specific proof of whether they are dead or alive or biased. The synthetic minority and oversampling technique analysis is used to equilibrium the class labels. This technique adds the records and labels synthetically by using three or more records to add one record. The sampling error is reduced to a minimum using the method described earlier. Pruning procedures apply to data that are inconsequential by cleansing the rules. Cross-validation is utilized to oversee the association and determinants’ 95% split. Figure 2 depicts the mortality prediction model of the under-five child (MPM-UFC) model.

Mortality prediction model of the under-five child (MPM-UFC).
The data are arranged using supervised classification, which uses predefined classes. The categorization uses the designated class to organize features in gathered information previously associated with class labels. Classifiers learn by training on a group of objects and then building a model to categorize the new objects [9].
A decision tree is commonly used to classify labels in the healthcare area. In the J48 decision tree classifier, a tree-like graph is used. A decision tree is a regularly utilized classifier for ineffective research analytics and determines conditional probabilities [10,11]. Pruning rule-based classification tree is the second classifier used to classify the labels (PART). The binary tree created by the decision tree J48 is a practical classification problem. When a tree is constructed, the labels are classified [12]. The J48 can be ranked in two ways: using rules developed from them or a decision tree.
The random forest was also used to categorize the classes’ labels to see which classifier performed the best on the dataset. The random forest extracts the subsections from the dataset and bootstraps a new dataset of a similar size. The bootstrap dataset contains trees built by decision trees, each taking its input. A poll of all trees assigns the new input to the class label. The maximum nominated class label is obtained through J48 for the fresh input. This classifier’s procedure selects a sample randomly. As a result, some samples may be overlooked [13].
Utilizing the aforementioned formula, bagging was calculated. The bag illustrates how bagging is repeated. FB is a classification tree that has been trained on the training set.
In the healthcare industry, the Bayesian network (Bayes Net) classifier is also used to identify important determinants and confirm the posterior probability by using the prior probability and new data. It also performs exceptionally well in data analytics and generates the most precise classifier outputs [14,15].
The sample dataset also used a multilayer perceptron for classification. It is a multilayer feed-forward artificial neural network based on nodes. The layers of the network are completely interconnected. Input nodes represent a variety of attributes. The activation function is then applied to a linear combination of input with weights W and bias B [16]. The following is the formula for the activation function in multilevel perceptron.
By using the “Fisher’s score” data mining technique, one of the most effective and fruitful data mining techniques, the dataset’s most significant socioeconomic and demographic health factors are extracted. High-dimensional data necessitated a huge storage capacity and a high processing cost. As a result, lowering the dimension enhances learning performance [17]. This algorithm is mostly used to reduce nonrelevant features. However, removing irrelevant characteristics is insufficient to achieve optimal perceptions and patterns. The Kth. Fisher’s score can be used to calculate S i , which is
where i is the mean of the ith feature, ij and ij are the mean and variance of the ith feature in the jth class, respectively, and nj is the number of occurrences in the jth class. In addition, the score eliminates any unnecessary elements, which are widely employed in data analytics. Figure 3 presents the traits that Fisher’s score was used to retrieve. Weka 3.8 was used to perform the preprocessing.

Child mortality predictors ranked set using Fisher’s score algorithm.
The property with the strongest link with the target variable is chosen in data mining. It assigns a ranking to features that influence the IG findings. Figure 3 depicts the ranking of traits according to their values.
The following evaluation measures are used to assess the classification outcomes of various algorithms. Precision, recall, and accuracy are some of the terms used to describe various metrics.
The predictive values are positive and are called predictive positive values (PPVs). The ratio of all true PPVs to the total positive predictive values is known as precision (PPV). Precision is an integer between 0 and 1. The maximum predictive value, or best value, is shown by a precision of 1, whilst the lowest predictive value, or worst value, is indicated by precision of 0.
The precision calculation is represented by equation (5) based on the true-positive and false-positive values.
The classifier’s performance is evaluated using its accuracy. The percentage of truly recognized observations to all observations is known as the truly recognized observations to all observation’s percentage. Its value is between 0 and 1. The maximum accuracy value, or best value, is indicated by a precision of 1, while the lowest accuracy value, or worst value, is shown by a precision of 0.
The accuracy calculation formula is represented by equation (6). False-positive values are designated by FP, false-negative values by FN, true positive values by TP, and true negative values by TN. False-negative values are also marked by FP.
Another word that comes to mind is “sensitivity.” It is the proportion of positively sampled positive values to all positively classified positive values. A recall rating between 0 and 1 denotes a poor recollection, whereas a recall value of 0 denotes a strong recall.
3.4 Experiments and results
The training and testing portions of the labeled dataset are split 70:30. Weka employs predictive modeling. Seventy percent of the survey dataset has been used to train the model, while 30% of survey datasets are used to test it initially. Before executing the modeling on the test set, cross-validation is also performed. The results of various classification models are displayed below. Table 3 demonstrates the classification of algorithm accuracy and analysis with nine predictors using the EDHS dataset.
Classification and algorithm analysis with nine predictors using EDHS dataset
Algorithms | Precision | Accuracy (%) | FP rate | TP rate | Recall |
---|---|---|---|---|---|
Random forest | 0.978 | 97.83 | 0.075 | 0.976 | 0.976 |
Bayes net | 0.951 | 95.68 | 0.085 | 0.947 | 0.947 |
PART | 0.931 | 93.99 | 0.097 | 0.930 | 0.930 |
Multilayer perceptron | 0.847 | 85.15 | 0.221 | 0.842 | 0.842 |
J48 | 0.933 | 94.16 | 0.095 | 0.932 | 0.932 |
The Bayes Net, the best-performing classifier, achieved 97.83% accuracy by combining nine features. J48 has shown better performance with the same features and records in the literature. The Fisher’s score algorithm is run to a similar set of parameters, and the procedure returns the high-ranked features listed in Table 4.
Feature sets are evaluated based on how much information they provide
Predictors | Fisher’s score value |
---|---|
Breastfeeding | 0.3196 |
Age of mother | 0.4463 |
Mothers age at FB | 0.4521 |
Sex of child | 0.3916 |
Received family planning | 0.2568 |
Presence of diarrhea | 0.1743 |
Parental education | 0.3055 |
Mother occupation | 0.2517 |
Preceding birth interval | 0.2579 |
Place of residence | 0.1306 |
Maternal education | 0.2078 |
The attribute “mother age at first birth” had the highest score, around 1, indicating the highest importance for the correctness and strongly connected with the label, whereas “presence of diarrhea” received the lowest value. Thus, we applied the same classifier Bayes Net, Random Forest, j48, PART, and multilayer perceptron to eight top-ranked features. The Bayes Net outperformed with an accuracy of 95.68%, which is nearly equal when we utilized nine attributes. We can obtain the same accuracy with a smaller number of characteristics. The classification results for the eight qualities are listed in Table 5.
Classification and algorithm analysis with nine predictors using the EDHS dataset
Algorithms | Precision | Accuracy (%) | FP rate | TP rate | Recall |
---|---|---|---|---|---|
Random forest | 0.945 | 94.44 | 0.077 | 0.944 | 0.944 |
Bayes net | 0.951 | 95.68 | 0.085 | 0.947 | 0.947 |
J48 | 0.932 | 92.94 | 0.099 | 0.932 | 0.929 |
Multilayer perceptron | 0.850 | 83.64 | 0.241 | 0.836 | 0.836 |
PART | 0.934 | 93.18 | 0.100 | 0.929 | 0.932 |
On the EDHS dataset, the aforementioned results were obtained. These evaluation measures have never been utilized before in the literature. As a result, this study analyses precision, recall, true predicted rate, and erroneously predictive rate. Then we took the PDHS dataset and applied the classifiers mentioned earlier before applying the same Fisher’s score technique and the same eight features. The best classifier results in the PDHS data were reached using the same “Bayes Net” technique, which had an accuracy of 97.40%. The outcomes of the classifier and their assessment results metrics are shown in Table 6.
Accuracy and analysis of classification algorithms using PDHS dataset
Algorithms | Precision | Recall | TP rate | FP rate | Accuracy (%) |
---|---|---|---|---|---|
Random forest | 0.942 | 0.942 | 0.942 | 0.058 | 94.16 |
Bayes net | 0.976 | 0.974 | 0.974 | 0.037 | 97.40 |
J48 | 0.960 | 0.959 | 0.959 | 0.042 | 95.87 |
Multilayer perceptron | 0.779 | 0.779 | 0.779 | 0.221 | 77.94 |
PART | 0.960 | 0.959 | 0.959 | 0.042 | 95.89 |
3.5 Discussion
In comparison to wealthy nations, developing nations have a higher death rate per 1,000 births, making it impossible for them to meet SDGs. This study tries to identify the elements that influence the mortality of young children in Ethiopia and Pakistan. In this study, predictive analytics techniques will be employed.
Prediction in data is becoming increasingly prevalent in health care because there is a persistent need to forecast undiscovered patterns, linkages between variables, outcome labels, and other essential information in health care data [18]. Data mining provides efficient methods and other advantages, such as the diagnosis and identification of diseases. It helps the research community by leveraging and assisting in developing successful interventions in policies and maintaining individual health profiles in the development of drug recommendation systems [19,20].
The age of the mother at her first delivery, the mother’s age, breastfeeding, parental education, the child’s gender, the time between births, the mother’s occupation, her maternal education, whether she used family planning, where she lived, and whether she had diarrhea were all found to be predictors of infant death. In the majority of trials, there was a direct link between breastfeeding and lower infant mortality. Table 4 further emphasizes the significance of breastfeeding by demonstrating that it is the factor that Ethiopian and Pakistani demographic studies have found to be most effective in lowering infant death. Early breastfeeding reduces a child’s risk of dying, according to the research community [21,22]. Other research studies [23,24,25] have discovered a link between low birth weight, inadequate family planning, and the absence of a birth internal gap, and an enlarged risk of kid death. According to our research in Pakistan, children whose mothers have never utilized family planning services are less likely to pass away than children whose mothers have used [26,27,28]. Figure 3 shows that maternal age at first birth, maternal education, and the mother’s work are all important predictors of child mortality, especially in low- and middle-income nations like Pakistan. Figure 2 demonstrates the high correlation between demographic and socioeconomic factors and the target labels of dead and living. These factors detect from machine learning and ontologies developed that can help identifies the prominent indicators these findings agree with those of an Ethiopian investigation [29,30,31,32], which found similar results.
The study identified and ranked the factors highly connected with childhood mortality. We identified the demographic predictors of child mortality by applying statistical methods to survey data from the EDHS and PDHS, as shown in Table 6. In addition, this research will aid academics and practitioners in identifying and forecasting children at an upper risk of death. This research included the opinions of domain experts and compared them to the previous work on liver cancer prediction, tuberculosis prediction, and other performance predictions in the literature. In addition, this study will aid health professionals in improving facilities for teaching mothers and taking preventative measures to decrease demographic mortality, both of which benefit the public.
4 Conclusions and future work
Based on the survey datasets from Ethiopia and Pakistan, two case studies were completed. To identify the traits that are connected to child mortality. The study’s findings show that a number of variables, including the mother’s age at her first birth, her age at subsequent births, breast-feeding, parental qualification, the kid’s gender, the time between births, the mother’s occupation, her maternal education, her use of family planning, her residence, and the presence of diarrhea, are directly linked to children’s mortality.
They employed the Bayesian network, J48, PART, random forest, and multilayer perceptron in prior studies using their EDHS dataset. According to their findings, they produced a superior result with the Bayesian network than with other classifiers. Previously, only the J48 and PART classifiers were utilized in the research. J48 outperformed the other two approaches in this comparison. In this study, Fisher’s score was employed in conjunction with an advanced feature selection technique to provide eight top-ranked features out of a total of nine features that had previously been used. In Table 6, we demonstrate that we could attain higher accuracy by using the same classifiers on the PDHS and EDHS datasets with eight characteristics.
The algorithms employed in this study are extremely understandable and allow for easy clarification of the prediction outcome. As a result, the outcome was determined to be extremely favorable in terms of intervening in child health policies. Following this, future studies will involve developing an ideal and more general model that will encompass a broader range of demographic, socioeconomic, and genomic aspects and then combining the findings of data mining, a prediction approach, with the results of a knowledge-based system. There is a critical need to develop a powerful tool to predict child death by utilizing our data, which will serve as a beneficial intervention in the healthcare arena to support physicians in their decision-making.
Acknowledgements
The authors would like to express their gratitude to all reviewers who provided constructive feedback that helped to improve the manuscript and to Madam Rabbea Irfan, Dean of Academics, TMUC for their endless support and motivation to make this research more effective.
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Funding information: Authors state no funding involved.
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Conflict of interest: Authors state no conflict of interest.
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Data availability statement: The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.
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- Agriculture
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- Plant Sciences
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- Erratum
- Erratum to “Protein Z modulates the metastasis of lung adenocarcinoma cells”
- Erratum to “BRCA1 subcellular localization regulated by PI3K signaling pathway in triple-negative breast cancer MDA-MB-231 cells and hormone-sensitive T47D cells”
- Retraction
- Retraction to “Protocatechuic acid attenuates cerebral aneurysm formation and progression by inhibiting TNF-alpha/Nrf-2/NF-kB-mediated inflammatory mechanisms in experimental rats”
Articles in the same Issue
- Biomedical Sciences
- Systemic investigation of inetetamab in combination with small molecules to treat HER2-overexpressing breast and gastric cancers
- Immunosuppressive treatment for idiopathic membranous nephropathy: An updated network meta-analysis
- Identifying two pathogenic variants in a patient with pigmented paravenous retinochoroidal atrophy
- Effects of phytoestrogens combined with cold stress on sperm parameters and testicular proteomics in rats
- A case of pulmonary embolism with bad warfarin anticoagulant effects caused by E. coli infection
- Neutrophilia with subclinical Cushing’s disease: A case report and literature review
- Isoimperatorin alleviates lipopolysaccharide-induced periodontitis by downregulating ERK1/2 and NF-κB pathways
- Immunoregulation of synovial macrophages for the treatment of osteoarthritis
- Novel CPLANE1 c.8948dupT (p.P2984Tfs*7) variant in a child patient with Joubert syndrome
- Antiphospholipid antibodies and the risk of thrombosis in myeloproliferative neoplasms
- Immunological responses of septic rats to combination therapy with thymosin α1 and vitamin C
- High glucose and high lipid induced mitochondrial dysfunction in JEG-3 cells through oxidative stress
- Pharmacological inhibition of the ubiquitin-specific protease 8 effectively suppresses glioblastoma cell growth
- Levocarnitine regulates the growth of angiotensin II-induced myocardial fibrosis cells via TIMP-1
- Age-related changes in peripheral T-cell subpopulations in elderly individuals: An observational study
- Single-cell transcription analysis reveals the tumor origin and heterogeneity of human bilateral renal clear cell carcinoma
- Identification of iron metabolism-related genes as diagnostic signatures in sepsis by blood transcriptomic analysis
- Long noncoding RNA ACART knockdown decreases 3T3-L1 preadipocyte proliferation and differentiation
- Surgery, adjuvant immunotherapy plus chemotherapy and radiotherapy for primary malignant melanoma of the parotid gland (PGMM): A case report
- Dosimetry comparison with helical tomotherapy, volumetric modulated arc therapy, and intensity-modulated radiotherapy for grade II gliomas: A single‑institution case series
- Soy isoflavone reduces LPS-induced acute lung injury via increasing aquaporin 1 and aquaporin 5 in rats
- Refractory hypokalemia with sexual dysplasia and infertility caused by 17α-hydroxylase deficiency and triple X syndrome: A case report
- Meta-analysis of cancer risk among end stage renal disease undergoing maintenance dialysis
- 6-Phosphogluconate dehydrogenase inhibition arrests growth and induces apoptosis in gastric cancer via AMPK activation and oxidative stress
- Experimental study on the optimization of ANM33 release in foam cells
- Primary retroperitoneal angiosarcoma: A case report
- Metabolomic analysis-identified 2-hydroxybutyric acid might be a key metabolite of severe preeclampsia
- Malignant pleural effusion diagnosis and therapy
- Effect of spaceflight on the phenotype and proteome of Escherichia coli
- Comparison of immunotherapy combined with stereotactic radiotherapy and targeted therapy for patients with brain metastases: A systemic review and meta-analysis
- Activation of hypermethylated P2RY1 mitigates gastric cancer by promoting apoptosis and inhibiting proliferation
- Association between the VEGFR-2 -604T/C polymorphism (rs2071559) and type 2 diabetic retinopathy
- The role of IL-31 and IL-34 in the diagnosis and treatment of chronic periodontitis
- Triple-negative mouse breast cancer initiating cells show high expression of beta1 integrin and increased malignant features
- mNGS facilitates the accurate diagnosis and antibiotic treatment of suspicious critical CNS infection in real practice: A retrospective study
- The apatinib and pemetrexed combination has antitumor and antiangiogenic effects against NSCLC
- Radiotherapy for primary thyroid adenoid cystic carcinoma
- Design and functional preliminary investigation of recombinant antigen EgG1Y162–EgG1Y162 against Echinococcus granulosus
- Effects of losartan in patients with NAFLD: A meta-analysis of randomized controlled trial
- Bibliometric analysis of METTL3: Current perspectives, highlights, and trending topics
- Performance comparison of three scaling algorithms in NMR-based metabolomics analysis
- PI3K/AKT/mTOR pathway and its related molecules participate in PROK1 silence-induced anti-tumor effects on pancreatic cancer
- The altered expression of cytoskeletal and synaptic remodeling proteins during epilepsy
- Effects of pegylated recombinant human granulocyte colony-stimulating factor on lymphocytes and white blood cells of patients with malignant tumor
- Prostatitis as initial manifestation of Chlamydia psittaci pneumonia diagnosed by metagenome next-generation sequencing: A case report
- NUDT21 relieves sevoflurane-induced neurological damage in rats by down-regulating LIMK2
- Association of interleukin-10 rs1800896, rs1800872, and interleukin-6 rs1800795 polymorphisms with squamous cell carcinoma risk: A meta-analysis
- Exosomal HBV-DNA for diagnosis and treatment monitoring of chronic hepatitis B
- Shear stress leads to the dysfunction of endothelial cells through the Cav-1-mediated KLF2/eNOS/ERK signaling pathway under physiological conditions
- Interaction between the PI3K/AKT pathway and mitochondrial autophagy in macrophages and the leukocyte count in rats with LPS-induced pulmonary infection
- Meta-analysis of the rs231775 locus polymorphism in the CTLA-4 gene and the susceptibility to Graves’ disease in children
- Cloning, subcellular localization and expression of phosphate transporter gene HvPT6 of hulless barley
- Coptisine mitigates diabetic nephropathy via repressing the NRLP3 inflammasome
- Significant elevated CXCL14 and decreased IL-39 levels in patients with tuberculosis
- Whole-exome sequencing applications in prenatal diagnosis of fetal bowel dilatation
- Gemella morbillorum infective endocarditis: A case report and literature review
- An unusual ectopic thymoma clonal evolution analysis: A case report
- Severe cumulative skin toxicity during toripalimab combined with vemurafenib following toripalimab alone
- Detection of V. vulnificus septic shock with ARDS using mNGS
- Novel rare genetic variants of familial and sporadic pulmonary atresia identified by whole-exome sequencing
- The influence and mechanistic action of sperm DNA fragmentation index on the outcomes of assisted reproduction technology
- Novel compound heterozygous mutations in TELO2 in an infant with You-Hoover-Fong syndrome: A case report and literature review
- ctDNA as a prognostic biomarker in resectable CLM: Systematic review and meta-analysis
- Diagnosis of primary amoebic meningoencephalitis by metagenomic next-generation sequencing: A case report
- Phylogenetic analysis of promoter regions of human Dolichol kinase (DOLK) and orthologous genes using bioinformatics tools
- Collagen changes in rabbit conjunctiva after conjunctival crosslinking
- Effects of NM23 transfection of human gastric carcinoma cells in mice
- Oral nifedipine and phytosterol, intravenous nicardipine, and oral nifedipine only: Three-arm, retrospective, cohort study for management of severe preeclampsia
- Case report of hepatic retiform hemangioendothelioma: A rare tumor treated with ultrasound-guided microwave ablation
- Curcumin induces apoptosis in human hepatocellular carcinoma cells by decreasing the expression of STAT3/VEGF/HIF-1α signaling
- Rare presentation of double-clonal Waldenström macroglobulinemia with pulmonary embolism: A case report
- Giant duplication of the transverse colon in an adult: A case report and literature review
- Ectopic thyroid tissue in the breast: A case report
- SDR16C5 promotes proliferation and migration and inhibits apoptosis in pancreatic cancer
- Vaginal metastasis from breast cancer: A case report
- Screening of the best time window for MSC transplantation to treat acute myocardial infarction with SDF-1α antibody-loaded targeted ultrasonic microbubbles: An in vivo study in miniswine
- Inhibition of TAZ impairs the migration ability of melanoma cells
- Molecular complexity analysis of the diagnosis of Gitelman syndrome in China
- Effects of maternal calcium and protein intake on the development and bone metabolism of offspring mice
- Identification of winter wheat pests and diseases based on improved convolutional neural network
- Ultra-multiplex PCR technique to guide treatment of Aspergillus-infected aortic valve prostheses
- Virtual high-throughput screening: Potential inhibitors targeting aminopeptidase N (CD13) and PIKfyve for SARS-CoV-2
- Immune checkpoint inhibitors in cancer patients with COVID-19
- Utility of methylene blue mixed with autologous blood in preoperative localization of pulmonary nodules and masses
- Integrated analysis of the microbiome and transcriptome in stomach adenocarcinoma
- Berberine suppressed sarcopenia insulin resistance through SIRT1-mediated mitophagy
- DUSP2 inhibits the progression of lupus nephritis in mice by regulating the STAT3 pathway
- Lung abscess by Fusobacterium nucleatum and Streptococcus spp. co-infection by mNGS: A case series
- Genetic alterations of KRAS and TP53 in intrahepatic cholangiocarcinoma associated with poor prognosis
- Granulomatous polyangiitis involving the fourth ventricle: Report of a rare case and a literature review
- Studying infant mortality: A demographic analysis based on data mining models
- Metaplastic breast carcinoma with osseous differentiation: A report of a rare case and literature review
- Protein Z modulates the metastasis of lung adenocarcinoma cells
- Inhibition of pyroptosis and apoptosis by capsaicin protects against LPS-induced acute kidney injury through TRPV1/UCP2 axis in vitro
- TAK-242, a toll-like receptor 4 antagonist, against brain injury by alleviates autophagy and inflammation in rats
- Primary mediastinum Ewing’s sarcoma with pleural effusion: A case report and literature review
- Association of ADRB2 gene polymorphisms and intestinal microbiota in Chinese Han adolescents
- Tanshinone IIA alleviates chondrocyte apoptosis and extracellular matrix degeneration by inhibiting ferroptosis
- Study on the cytokines related to SARS-Cov-2 in testicular cells and the interaction network between cells based on scRNA-seq data
- Effect of periostin on bone metabolic and autophagy factors during tooth eruption in mice
- HP1 induces ferroptosis of renal tubular epithelial cells through NRF2 pathway in diabetic nephropathy
- Intravaginal estrogen management in postmenopausal patients with vaginal squamous intraepithelial lesions along with CO2 laser ablation: A retrospective study
- Hepatocellular carcinoma cell differentiation trajectory predicts immunotherapy, potential therapeutic drugs, and prognosis of patients
- Effects of physical exercise on biomarkers of oxidative stress in healthy subjects: A meta-analysis of randomized controlled trials
- Identification of lysosome-related genes in connection with prognosis and immune cell infiltration for drug candidates in head and neck cancer
- Development of an instrument-free and low-cost ELISA dot-blot test to detect antibodies against SARS-CoV-2
- Research progress on gas signal molecular therapy for Parkinson’s disease
- Adiponectin inhibits TGF-β1-induced skin fibroblast proliferation and phenotype transformation via the p38 MAPK signaling pathway
- The G protein-coupled receptor-related gene signatures for predicting prognosis and immunotherapy response in bladder urothelial carcinoma
- α-Fetoprotein contributes to the malignant biological properties of AFP-producing gastric cancer
- CXCL12/CXCR4/CXCR7 axis in placenta tissues of patients with placenta previa
- Association between thyroid stimulating hormone levels and papillary thyroid cancer risk: A meta-analysis
- Significance of sTREM-1 and sST2 combined diagnosis for sepsis detection and prognosis prediction
- Diagnostic value of serum neuroactive substances in the acute exacerbation of chronic obstructive pulmonary disease complicated with depression
- Research progress of AMP-activated protein kinase and cardiac aging
- TRIM29 knockdown prevented the colon cancer progression through decreasing the ubiquitination levels of KRT5
- Cross-talk between gut microbiota and liver steatosis: Complications and therapeutic target
- Metastasis from small cell lung cancer to ovary: A case report
- The early diagnosis and pathogenic mechanisms of sepsis-related acute kidney injury
- The effect of NK cell therapy on sepsis secondary to lung cancer: A case report
- Erianin alleviates collagen-induced arthritis in mice by inhibiting Th17 cell differentiation
- Loss of ACOX1 in clear cell renal cell carcinoma and its correlation with clinical features
- Signalling pathways in the osteogenic differentiation of periodontal ligament stem cells
- Crosstalk between lactic acid and immune regulation and its value in the diagnosis and treatment of liver failure
- Clinicopathological features and differential diagnosis of gastric pleomorphic giant cell carcinoma
- Traumatic brain injury and rTMS-ERPs: Case report and literature review
- Extracellular fibrin promotes non-small cell lung cancer progression through integrin β1/PTEN/AKT signaling
- Knockdown of DLK4 inhibits non-small cell lung cancer tumor growth by downregulating CKS2
- The co-expression pattern of VEGFR-2 with indicators related to proliferation, apoptosis, and differentiation of anagen hair follicles
- Inflammation-related signaling pathways in tendinopathy
- CD4+ T cell count in HIV/TB co-infection and co-occurrence with HL: Case report and literature review
- Clinical analysis of severe Chlamydia psittaci pneumonia: Case series study
- Bioinformatics analysis to identify potential biomarkers for the pulmonary artery hypertension associated with the basement membrane
- Influence of MTHFR polymorphism, alone or in combination with smoking and alcohol consumption, on cancer susceptibility
- Catharanthus roseus (L.) G. Don counteracts the ampicillin resistance in multiple antibiotic-resistant Staphylococcus aureus by downregulation of PBP2a synthesis
- Combination of a bronchogenic cyst in the thoracic spinal canal with chronic myelocytic leukemia
- Bacterial lipoprotein plays an important role in the macrophage autophagy and apoptosis induced by Salmonella typhimurium and Staphylococcus aureus
- TCL1A+ B cells predict prognosis in triple-negative breast cancer through integrative analysis of single-cell and bulk transcriptomic data
- Ezrin promotes esophageal squamous cell carcinoma progression via the Hippo signaling pathway
- Ferroptosis: A potential target of macrophages in plaque vulnerability
- Predicting pediatric Crohn's disease based on six mRNA-constructed risk signature using comprehensive bioinformatic approaches
- Applications of genetic code expansion and photosensitive UAAs in studying membrane proteins
- HK2 contributes to the proliferation, migration, and invasion of diffuse large B-cell lymphoma cells by enhancing the ERK1/2 signaling pathway
- IL-17 in osteoarthritis: A narrative review
- Circadian cycle and neuroinflammation
- Probiotic management and inflammatory factors as a novel treatment in cirrhosis: A systematic review and meta-analysis
- Hemorrhagic meningioma with pulmonary metastasis: Case report and literature review
- SPOP regulates the expression profiles and alternative splicing events in human hepatocytes
- Knockdown of SETD5 inhibited glycolysis and tumor growth in gastric cancer cells by down-regulating Akt signaling pathway
- PTX3 promotes IVIG resistance-induced endothelial injury in Kawasaki disease by regulating the NF-κB pathway
- Pancreatic ectopic thyroid tissue: A case report and analysis of literature
- The prognostic impact of body mass index on female breast cancer patients in underdeveloped regions of northern China differs by menopause status and tumor molecular subtype
- Report on a case of liver-originating malignant melanoma of unknown primary
- Case report: Herbal treatment of neutropenic enterocolitis after chemotherapy for breast cancer
- The fibroblast growth factor–Klotho axis at molecular level
- Characterization of amiodarone action on currents in hERG-T618 gain-of-function mutations
- A case report of diagnosis and dynamic monitoring of Listeria monocytogenes meningitis with NGS
- Effect of autologous platelet-rich plasma on new bone formation and viability of a Marburg bone graft
- Small breast epithelial mucin as a useful prognostic marker for breast cancer patients
- Continuous non-adherent culture promotes transdifferentiation of human adipose-derived stem cells into retinal lineage
- Nrf3 alleviates oxidative stress and promotes the survival of colon cancer cells by activating AKT/BCL-2 signal pathway
- Favorable response to surufatinib in a patient with necrolytic migratory erythema: A case report
- Case report of atypical undernutrition of hypoproteinemia type
- Down-regulation of COL1A1 inhibits tumor-associated fibroblast activation and mediates matrix remodeling in the tumor microenvironment of breast cancer
- Sarcoma protein kinase inhibition alleviates liver fibrosis by promoting hepatic stellate cells ferroptosis
- Research progress of serum eosinophil in chronic obstructive pulmonary disease and asthma
- Clinicopathological characteristics of co-existing or mixed colorectal cancer and neuroendocrine tumor: Report of five cases
- Role of menopausal hormone therapy in the prevention of postmenopausal osteoporosis
- Precisional detection of lymph node metastasis using tFCM in colorectal cancer
- Advances in diagnosis and treatment of perimenopausal syndrome
- A study of forensic genetics: ITO index distribution and kinship judgment between two individuals
- Acute lupus pneumonitis resembling miliary tuberculosis: A case-based review
- Plasma levels of CD36 and glutathione as biomarkers for ruptured intracranial aneurysm
- Fractalkine modulates pulmonary angiogenesis and tube formation by modulating CX3CR1 and growth factors in PVECs
- Novel risk prediction models for deep vein thrombosis after thoracotomy and thoracoscopic lung cancer resections, involving coagulation and immune function
- Exploring the diagnostic markers of essential tremor: A study based on machine learning algorithms
- Evaluation of effects of small-incision approach treatment on proximal tibia fracture by deep learning algorithm-based magnetic resonance imaging
- An online diagnosis method for cancer lesions based on intelligent imaging analysis
- Medical imaging in rheumatoid arthritis: A review on deep learning approach
- Predictive analytics in smart healthcare for child mortality prediction using a machine learning approach
- Utility of neutrophil–lymphocyte ratio and platelet–lymphocyte ratio in predicting acute-on-chronic liver failure survival
- A biomedical decision support system for meta-analysis of bilateral upper-limb training in stroke patients with hemiplegia
- TNF-α and IL-8 levels are positively correlated with hypobaric hypoxic pulmonary hypertension and pulmonary vascular remodeling in rats
- Stochastic gradient descent optimisation for convolutional neural network for medical image segmentation
- Comparison of the prognostic value of four different critical illness scores in patients with sepsis-induced coagulopathy
- Application and teaching of computer molecular simulation embedded technology and artificial intelligence in drug research and development
- Hepatobiliary surgery based on intelligent image segmentation technology
- Value of brain injury-related indicators based on neural network in the diagnosis of neonatal hypoxic-ischemic encephalopathy
- Analysis of early diagnosis methods for asymmetric dementia in brain MR images based on genetic medical technology
- Early diagnosis for the onset of peri-implantitis based on artificial neural network
- Clinical significance of the detection of serum IgG4 and IgG4/IgG ratio in patients with thyroid-associated ophthalmopathy
- Forecast of pain degree of lumbar disc herniation based on back propagation neural network
- SPA-UNet: A liver tumor segmentation network based on fused multi-scale features
- Systematic evaluation of clinical efficacy of CYP1B1 gene polymorphism in EGFR mutant non-small cell lung cancer observed by medical image
- Rehabilitation effect of intelligent rehabilitation training system on hemiplegic limb spasms after stroke
- A novel approach for minimising anti-aliasing effects in EEG data acquisition
- ErbB4 promotes M2 activation of macrophages in idiopathic pulmonary fibrosis
- Clinical role of CYP1B1 gene polymorphism in prediction of postoperative chemotherapy efficacy in NSCLC based on individualized health model
- Lung nodule segmentation via semi-residual multi-resolution neural networks
- Evaluation of brain nerve function in ICU patients with Delirium by deep learning algorithm-based resting state MRI
- A data mining technique for detecting malignant mesothelioma cancer using multiple regression analysis
- Markov model combined with MR diffusion tensor imaging for predicting the onset of Alzheimer’s disease
- Effectiveness of the treatment of depression associated with cancer and neuroimaging changes in depression-related brain regions in patients treated with the mediator-deuterium acupuncture method
- Molecular mechanism of colorectal cancer and screening of molecular markers based on bioinformatics analysis
- Monitoring and evaluation of anesthesia depth status data based on neuroscience
- Exploring the conformational dynamics and thermodynamics of EGFR S768I and G719X + S768I mutations in non-small cell lung cancer: An in silico approaches
- Optimised feature selection-driven convolutional neural network using gray level co-occurrence matrix for detection of cervical cancer
- Incidence of different pressure patterns of spinal cerebellar ataxia and analysis of imaging and genetic diagnosis
- Pathogenic bacteria and treatment resistance in older cardiovascular disease patients with lung infection and risk prediction model
- Adoption value of support vector machine algorithm-based computed tomography imaging in the diagnosis of secondary pulmonary fungal infections in patients with malignant hematological disorders
- From slides to insights: Harnessing deep learning for prognostic survival prediction in human colorectal cancer histology
- Ecology and Environmental Science
- Monitoring of hourly carbon dioxide concentration under different land use types in arid ecosystem
- Comparing the differences of prokaryotic microbial community between pit walls and bottom from Chinese liquor revealed by 16S rRNA gene sequencing
- Effects of cadmium stress on fruits germination and growth of two herbage species
- Bamboo charcoal affects soil properties and bacterial community in tea plantations
- Optimization of biogas potential using kinetic models, response surface methodology, and instrumental evidence for biodegradation of tannery fleshings during anaerobic digestion
- Understory vegetation diversity patterns of Platycladus orientalis and Pinus elliottii communities in Central and Southern China
- Studies on macrofungi diversity and discovery of new species of Abortiporus from Baotianman World Biosphere Reserve
- Food Science
- Effect of berrycactus fruit (Myrtillocactus geometrizans) on glutamate, glutamine, and GABA levels in the frontal cortex of rats fed with a high-fat diet
- Guesstimate of thymoquinone diversity in Nigella sativa L. genotypes and elite varieties collected from Indian states using HPTLC technique
- Analysis of bacterial community structure of Fuzhuan tea with different processing techniques
- Untargeted metabolomics reveals sour jujube kernel benefiting the nutritional value and flavor of Morchella esculenta
- Mycobiota in Slovak wine grapes: A case study from the small Carpathians wine region
- Elemental analysis of Fadogia ancylantha leaves used as a nutraceutical in Mashonaland West Province, Zimbabwe
- Microbiological transglutaminase: Biotechnological application in the food industry
- Influence of solvent-free extraction of fish oil from catfish (Clarias magur) heads using a Taguchi orthogonal array design: A qualitative and quantitative approach
- Chromatographic analysis of the chemical composition and anticancer activities of Curcuma longa extract cultivated in Palestine
- The potential for the use of leghemoglobin and plant ferritin as sources of iron
- Investigating the association between dietary patterns and glycemic control among children and adolescents with T1DM
- Bioengineering and Biotechnology
- Biocompatibility and osteointegration capability of β-TCP manufactured by stereolithography 3D printing: In vitro study
- Clinical characteristics and the prognosis of diabetic foot in Tibet: A single center, retrospective study
- Agriculture
- Biofertilizer and NPSB fertilizer application effects on nodulation and productivity of common bean (Phaseolus vulgaris L.) at Sodo Zuria, Southern Ethiopia
- On correlation between canopy vegetation and growth indexes of maize varieties with different nitrogen efficiencies
- Exopolysaccharides from Pseudomonas tolaasii inhibit the growth of Pleurotus ostreatus mycelia
- A transcriptomic evaluation of the mechanism of programmed cell death of the replaceable bud in Chinese chestnut
- Melatonin enhances salt tolerance in sorghum by modulating photosynthetic performance, osmoregulation, antioxidant defense, and ion homeostasis
- Effects of plant density on alfalfa (Medicago sativa L.) seed yield in western Heilongjiang areas
- Identification of rice leaf diseases and deficiency disorders using a novel DeepBatch technique
- Artificial intelligence and internet of things oriented sustainable precision farming: Towards modern agriculture
- Animal Sciences
- Effect of ketogenic diet on exercise tolerance and transcriptome of gastrocnemius in mice
- Combined analysis of mRNA–miRNA from testis tissue in Tibetan sheep with different FecB genotypes
- Isolation, identification, and drug resistance of a partially isolated bacterium from the gill of Siniperca chuatsi
- Tracking behavioral changes of confined sows from the first mating to the third parity
- The sequencing of the key genes and end products in the TLR4 signaling pathway from the kidney of Rana dybowskii exposed to Aeromonas hydrophila
- Development of a new candidate vaccine against piglet diarrhea caused by Escherichia coli
- Plant Sciences
- Crown and diameter structure of pure Pinus massoniana Lamb. forest in Hunan province, China
- Genetic evaluation and germplasm identification analysis on ITS2, trnL-F, and psbA-trnH of alfalfa varieties germplasm resources
- Tissue culture and rapid propagation technology for Gentiana rhodantha
- Effects of cadmium on the synthesis of active ingredients in Salvia miltiorrhiza
- Cloning and expression analysis of VrNAC13 gene in mung bean
- Chlorate-induced molecular floral transition revealed by transcriptomes
- Effects of warming and drought on growth and development of soybean in Hailun region
- Effects of different light conditions on transient expression and biomass in Nicotiana benthamiana leaves
- Comparative analysis of the rhizosphere microbiome and medicinally active ingredients of Atractylodes lancea from different geographical origins
- Distinguish Dianthus species or varieties based on chloroplast genomes
- Comparative transcriptomes reveal molecular mechanisms of apple blossoms of different tolerance genotypes to chilling injury
- Study on fresh processing key technology and quality influence of Cut Ophiopogonis Radix based on multi-index evaluation
- An advanced approach for fig leaf disease detection and classification: Leveraging image processing and enhanced support vector machine methodology
- Erratum
- Erratum to “Protein Z modulates the metastasis of lung adenocarcinoma cells”
- Erratum to “BRCA1 subcellular localization regulated by PI3K signaling pathway in triple-negative breast cancer MDA-MB-231 cells and hormone-sensitive T47D cells”
- Retraction
- Retraction to “Protocatechuic acid attenuates cerebral aneurysm formation and progression by inhibiting TNF-alpha/Nrf-2/NF-kB-mediated inflammatory mechanisms in experimental rats”