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Clinical diagnosis, prevention, and treatment of neurodyspepsia syndrome using intelligent medicine

  • Jingyu Zhu , Wei Meng , Liang Liu , Peixin Hu , Yuling Liang , Wenwen Zhu and Xiaoyan Zhu EMAIL logo
Published/Copyright: May 7, 2024
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Open Life Sciences
From the journal Open Life Sciences Volume 19 Issue 1

Abstract

Against the backdrop of rapid social economy and scientific and technological development, intelligent medical technology expanded based on the Internet plays a crucial role in the innovation and development of the modern medical industry. Intelligent medical technology has completely changed the fixed medical methods of the past, and it can solve the isolated defects between various unit systems, greatly improving the overall informatization level of hospitals. This article analyzed the clinical diagnosis, prevention, and treatment of neurodyspepsia syndrome (NDS) in intelligent medicine. Dyspepsia can cause palpitations, vomiting, abdominal distension, dizziness, and other symptoms so that it can cause discomfort and pain in the middle or around the epigastric region. Therefore, it is necessary to make a correct diagnosis of neurodyspepsia in order to reduce the discomfort of patients. Intelligent medical technology is of great significance in improving patients’ symptoms. This study sets up a control group and an experimental group for the experiment. The control group used conventional medication technology, while the experimental group used intelligent medical technology to analyze the patient samples taken. By comparing the factors that affect patients with NDS, it was found that the physical function score of the experimental group was 6.3% lower than that of the control group. Intelligent medical technology has high diagnostic efficiency and can achieve rapid diagnosis of NDS, meeting the clinical diagnosis and prevention requirements of NDS.

Graphical abstract

Keywords: intelligent medical treatment; neurodyspepsia syndrome; internet of things technology; clinical diagnosis

1 Introduction

Neurodyspepsia syndrome (NDS) is a common digestive disease, which is a series of symptoms caused by dysfunction of the upper gastrointestinal tract. The clinical manifestations of patients include palpitations, vomiting, abdominal distension, dizziness, etc. These symptoms usually last for more than 1 month. Previously, patients would use symptomatic regimens for treatment, but if only a single drug were used, its efficacy would be difficult to satisfy. In recent years, people’s understanding of this disease has become increasingly profound, and some studies have shown that the therapeutic effect of intelligent medicine has gradually become prominent, which can quickly detect digestive tract diseases.

Researchers in relevant fields have conducted research on indigestion syndrome and analyzed the causes of the patient’s illness. Burns analyzed the obvious symptoms that dyspepsia syndrome may exhibit, but due to the unclear molecular mechanism of gastrointestinal tissue and the need for further research on related inflammatory reactions, he drew on the symptoms and treatment plans of diseases related to “functional gastrointestinal disease,” “functional dyspepsia,” and “irritable bowel syndrome.” By analyzing the changes in the number of lymphocytes in the patient’s digestive tract, it was found that the imbalance of the digestive tract environment is an important reason for clinical manifestations [1]. Hanel et al. analyzed the incidence and mortality rate of indigestion syndrome and found that the incidence and treatment effect of indigestion syndrome were also on the rise. They used bioinformatics technology to study indigestion syndrome. By analyzing patients’ psychological factors, hormone levels, and changes in physical function, they found that some factors can lead to the occurrence of functional gastrointestinal diseases [2]. Koloski found potential immune activation and psychological distress in patients with indigestion syndrome. In a large-scale population-based study, he tested whether allergic or autoimmune diseases were associated with indigestion syndrome. The results indicated that testing for allergic or autoimmune diseases is associated with NDS [3]. Shah evaluated and compared the impact of antimicrobial therapy on patients with digestive syndrome. He measured the symptom response to standardized nutrition challenges based on the total score of gastrointestinal symptoms measured through questionnaires and subscales. After experimental analysis, it was found that the subscale of indigestion and diarrhea showed significant improvement in statistics. Similarly, symptom scores significantly improved after standardized nutrition challenges [4]. These authors have provided some suggestions and conclusions by analyzing indigestion syndrome.

In addition, the authors analyzed the factors that influence indigestion syndrome and obtained data on each influencing factor through investigation. Talley analyzed whether dyspepsia syndrome is associated with smoking and evaluated whether smoking is an independent risk factor for the disease. He evaluated patients during clinical visits using an abdominal symptom questionnaire. In the data meta-analysis, intelligent medical technology was used to analyze the impact of smoking on symptom status, and adjustments were made for smoking, age, and gender. It was found that smoking is an important environmental risk factor for indigestion syndrome [5]. Tack et al. analyzed the key pathological factors of indigestion syndrome and found that the use of first-cause drugs is often considered the preferred treatment method for the disease. Experimental analysis showed that first-cause drugs may be effective and safe for patients, but there is a lack of available and proven effective drugs [6]. Barberio analyzed the severity of symptoms of indigestion syndrome and data on mental health and found that in patient’s rehabilitation reports, the use of multiple medication methods is more effective. The treatment effect of using only one drug is poor, laying a foundation for future prevention, control, and diagnosis of digestive tract diseases [7]. However, the relevant content investigated by these researchers is insufficient to effectively address indigestion syndrome, and improvements in treatment plans and diagnostic techniques are needed.

This article analyzed the clinical diagnosis, prevention, and treatment methods of NDS using intelligent medical technology, and analyzed intelligent medical technology. The application of intelligent medical technology in the medical field was discussed, and the clinical diagnosis, prevention, and treatment plans for NDS were studied. This article applied intelligent medical technology to the diagnosis of NDS. Through experimental research, it was found that intelligent medical technology can more quickly treat and prevent NDS.

2 Intelligent healthcare

2.1 Current status of intelligent medical development

In the future, more high-tech technologies such as artificial intelligence and sensing technology will be introduced into the medical field, making medical services more intelligent and promoting the vigorous development of medicine. With the implementation of the new “medical reform” policy, intelligent healthcare has gradually entered people’s daily lives. As the birth rate of the population continues to decline, people are paying more and more attention to their physical condition, and people have higher and higher requirements for the health system. So, the combination of telemedicine and electronic medicine can bring great convenience to life. By utilizing technologies such as cloud computing and artificial intelligence expert terminals, a complete Internet of Things (IoT) health management system can be established, enabling everyone to enjoy first-class health management.

When IoT technology is applied to the medical field, the Drug Administration will take many practical measures to promote the implementation of these policies. Intelligent healthcare would be fully utilized in medical services, including medical information interconnection, medical service sharing, medical service innovation, and public health prevention and control. By providing a deeper level of service efficiency and service quality in intelligent healthcare, the overall management of the hospital is improved, and monitoring is brought to a wireless level, thus completely transforming and solving modern digital healthcare issues and problems. It greatly improves the sharing of medical resources and reduces public medical expenses.

By utilizing electronic medicine and IoT technology, a large amount of medical monitoring work can be wirelessly realized. Remote medicine and self-service medicine can collect and highly share information in a timely manner, thereby alleviating the difficulties of resource shortage and uneven distribution and reducing public medical expenses.

The development of intelligent medical services can be divided into seven levels: the first level is operational management, which mainly includes information such as hospital expenses and drugs; the second is an electronic medical record system composed of patient data and imaging data; the third is its clinical application, mainly including computer input of doctors’ medical orders, etc.; the fourth is to establish a governance system for chronic diseases; the fifth is to establish a regional medical and health information exchange system; the sixth is a medical assistance decision-making system; and the seventh is to establish a universal healthcare system. In the field of remote intelligent healthcare, some more developed hospitals have made technological improvements in mobile information applications, which would play a driving role in future intelligent healthcare.

2.2 Application of IoT technology in intelligent healthcare

Through the introduction of IoT technology, hospitals can track the location of patients, drugs, and medical waste. By utilizing portable mobile phones with wireless network access, patients’ conditions can be more accurately, timely, and comprehensively understood. By utilizing this system, real-time monitoring of the ward can be achieved. It can monitor the elderly and patients in real time and help them grasp their vital signs in a timely manner. “Remote medicine” is a new type of medical service. The organic integration of medical technology with computer technology, multimedia technology, and Internet technology can improve the effectiveness and quality of treatment and can reduce the cost of medicine, thus achieving a better response to people’s needs for health and medicine. On the basis of IoT technology, the construction of hospital informatization has become particularly crucial. Utilizing modern IoT technology and relevant terminal devices enables real-time tracking and monitoring of patient signs. This enables real-time diagnosis and health alerts for patients or subhealthy patients in hospitals, effectively reducing and controlling their diseases and thus improving work efficiency. Throughout the entire treatment process, reducing material consumption can reduce medical accidents and improve medical quality.

3 Neurogenic dyspepsia syndrome

3.1 Main symptoms of indigestion

As a common digestive disorder, dyspepsia is associated with the development of receptive relaxation of the gastric fundus, visceral hypersensitivity, and gastrointestinal motility disorders after diet, as well as environmental, social, and spiritual factors. In recent years, due to the rapid development of life and the increasing speed of life, there have been significant changes in lifestyle and dietary structure. In addition, the stress of work has led to a gradual increase in the incidence of this disease.

The symptoms of indigestion are closely related to gastric syndrome and gastric spasms. Gastrointestinal symptoms typically manifest as delayed digestion in the stomach. During treatment, patients with indigestion are reclassified and differentiated based on the severity of the symptoms [8]. Dyspepsia syndrome is related to the quality of life and psychological status of patients. The symptoms of outpatient patients in tertiary hospitals mainly include diarrhea and constipation. These gastrointestinal symptoms affect the evaluation of the causes of patients’ illnesses, and psychological factors are important factors affecting gastrointestinal diseases [9].

The symptoms of indigestion vary in the digestive system and gastrointestinal tract, and doctors provide targeted treatment for potential patients. Functional dyspepsia can provide clinical experience for the study of overlapping gastrointestinal diseases. It has many clinical reactions, such as residual returning flow in the esophagus, postprandial pain syndrome, and digestive discharge difficulties. The study of the above symptoms provides a basis for the physiology of pathology [10]. Esophageal duodenoscopy in children found that more than half of cases with NDS showed signs of stomach disease, and destructive ulcerated lesions were diagnosed in almost all age groups. The frequency of such lesions increased in adolescents [11].

From the perspective of traditional Chinese medicine, gastrointestinal dysfunction can be classified into the categories of pathogenesis, such as “epigastric pain” and “gastric distension.” In traditional Chinese medicine theory, changes in mood, improper diet, and weather conditions lead to a complex pathological process of liver fire and spleen stomach disharmony. Dyspepsia is a common disease in clinical practice, characterized by a long course of disease and a tendency to recur. If the patient’s quality of life is poor, effective measures must be taken to help them recover.

Liver depression and spleen deficiency-type dyspepsia syndrome are also a common disease, and their etiology is not yet fully understood. Through clinical pharmacological analysis of traditional Chinese medicine, it was found that Shugan Jianpi Tang is suitable for the clinical symptoms of gastrointestinal diseases with liver stagnation and spleen deficiency, thereby helping patients recover as soon as possible.

In addition, modern pharmacological studies have shown that “bergamot heart” has anti-depression, antibacterial properties, and certain protective effects on gastrointestinal cells. Fructus Aurantii and Radix Bupleuri have the effect of improving intestinal emptying and intestinal function, especially since Radix Bupleuri has anti-inflammatory and gastrointestinal regulating effects. Some of the therapeutic effects of other drugs are very good. This article analyzed the causes of this phenomenon and believed that the main reasons are the following: these drugs can regulate the central nervous system of the hypothalamus and enhance the vagus nerve; at the same time, they can also promote the secretion of gastric juice. The causes of indigestion include increased gastric acid secretion caused by sympathetic nerve stimulation and imbalance of vagal sympathetic inhibition, resulting in stomach disease with liver stagnation and spleen deficiency. Through the cerebral cortex, the cerebral cortex center and hypothalamus are abnormal, so the sympathetic nerve in the brain is hyperactive. After that, its release pulse is enhanced, which lasts for a long time, and finally, the digestive tract is abnormal. Based on the analysis of traditional Chinese medicine, clinical symptoms are alleviated and contribute to rehabilitation.

3.2 Diagnosis and treatment plan for indigestion syndrome

3.2.1 Diagnosis of neurodyspepsia

Neurodyspepsia can cause damage to any segment of the digestive tract along the gastric wall, starting from the brainstem. Along the farthest segment, it can cause damage to the vagus nerve and its branches, leading to inflammatory reactions or dysfunction. The above situations can cause gastrointestinal dysfunction and are classified as indigestion. According to the location and severity of the damage, its clinical symptoms vary. Generally, neurodyspepsia manifests as intermittent or persistent, often associated with functional overflow obstruction or vomiting symptoms.

Abdominal ultrasound is of great help in the diagnosis of neurodyspepsia. Ultrasound can help determine the characteristics of abdominal fluid and whether there is fibrosis or abscess, as well as determine the size of organs and other similar tumor diseases. However, currently, the sensitivity and specificity of clinical diagnosis for neurodyspepsia are low; therefore, abdominal ultrasound is the best auxiliary examination method. When the equipment is complete, X-ray images of the gastric reticulum are very useful for detecting perforated foreign bodies in the gastric reticulum. X-ray images of the larynx and chest are also useful for the diagnosis of diseases in the larynx and chest, and cytological testing of tumor cells is performed after peritoneal puncture.

Neurodyspepsia includes symptoms such as dyspepsia and irritable bowel syndrome. By investigating the impact of symptom overlap on the burden of symptoms in NDS, it is found that overlapping dyspepsia in NDS is related to different clinical and psychological characteristics. By screening patient data from the population, it is possible to compare the treatment effects of subjects who use drugs alone and those who overlap two or three drugs [12]. By analyzing the gastric regulation of patients after meals, doctors can find that gastric fundus regulation may lead to a temporary increase in relaxation of the lower esophageal sphincter, leading to gastroesophageal reflux. Functional dyspepsia, as a common disease, affects the normal life of patients. In diagnosis, endoscopic examination of the digestive tract is required, and inhibitors can be used to treat the disease [13].

Medication is administered in a population of children with postprandial pain syndrome due to neurodyspepsia, and clinical reactions and safety are observed. Clinical reactions are divided into complete response, partial response, and no response. The prescribed dosage, side effects, and weight changes during medication treatment can all affect the observed results. The most common adverse reactions are weight gain and restlessness. Medication therapy is an option for treating functional nausea and dyspepsia syndrome in children and adolescents, especially for patients with concurrent weight loss, anxiety, and insomnia [14]. The neural mechanisms of gastrointestinal interactions and visceral hypersensitivity reactions are closely related. The use of advanced imaging techniques such as magnetic resonance imaging for diagnosis has been recognized by clinical doctors and radiologists in the diagnosis of gastrointestinal diseases. The research results on the population of patients with NDS demonstrate that psychological and social factors affect the mechanism of regulating visceral sensitivity in the brain. Psychological processes can affect the function of the digestive system and may lead to symptoms of indigestion. The mental state related to stress in patients can affect the processes that occur in the central nervous system and trigger somatic reactions in the digestive tract through the autonomic visceral system [15]. The treatment plan for NDS using intelligent medicine is shown in Figure 1.

Figure 1 The treatment plan of intelligent medicine for NDS.
Figure 1

The treatment plan of intelligent medicine for NDS.

3.2.2 Treatment plan for neurodyspepsia

Some primary symptoms of neurodyspepsia, such as tumors, gastric torsion, and stomach pain caused by peritonitis, are often difficult to treat [16,17]. Primary diseases such as pharyngeal trauma, severe pneumonia, and other injuries that cause vomiting disorders only require treatment, such as pharyngitis and cellulitis, which can be treated with oral broad-spectrum antibiotics, anti-inflammatory drugs, and analgesics [18]. For the above patients, if they have refractory vomiting symptoms, a rumen fistula can be established to alleviate long-term vomiting symptoms, and then diet and standing water treatment can be carried out through this method [19]. In valuable diseases, if the cause is in the abdomen, surgical treatment is necessary. For some primary causes of neurodyspepsia, the best approach is to undergo open surgery and gastrotomy. This not only helps doctors diagnose and judge the condition clearly, but also helps patients empty food from the stomach, thereby reducing the pressure on nerve receptors [20].

When this damage is reversible, it can restore the stomach to a normal contractile state. Before surgery, intravenous infusion is needed to restore water in the body and adjust the pH and electrolytes in the body. If it may be caused by peritonitis, timely antibiotic treatment is necessary. Due to the functional emptying of the gastrointestinal tract, oral liquid supplementation or oral medication should be prohibited [21,22]. When there is low calcium in the blood, patients should be injected with calcium to compensate for nutrient loss caused by decreased absorption in the digestive tract. When performing surgery, it is important to conduct a complete and thorough examination as much as possible. If there is a large amount of adhesion in the abdomen or stomach, it is necessary to avoid contact or damage as much as possible to avoid inflammation and pain. After that, there is tumor resection, digestion, and evacuation.

Targeted treatment methods should be adopted for the primary causes of neurogenic dyspepsia. Patients with acute peritonitis and abscesses should be treated with antibiotics, and attention should be paid to adjusting the electrolyte balance. When symptoms are severe, patients may experience stubborn decreased appetite, decreased bowel movements, recurrent swelling, abdominal distension, and other symptoms. After just completing the surgery, the patient should not have a lot of food in their stomach. There are also individual patients who overeat or drink too much water after surgery. If left unchecked, it can cause rapid swelling of the stomach again. The treatment process of patients with NDS is shown in Figure 2.

Figure 2 The treatment process of patients with NDS.
Figure 2

The treatment process of patients with NDS.

4 NDS experiment

4.1 Experimental description

One hundred patients with indigestion syndrome were selected and divided into an experimental group and a control group, with 50 cases in each group. Based on clinical diagnosis and pathological analysis, there were 22 males and 28 females in the control group. There were 26 males and 24 females in the experimental group. The data from the control and experimental groups were compared for statistical significance. The selection of experimental data is shown in Table 1.

Table 1

Selection of experimental data

Group Number of male patients Number of female patients Therapeutic method
Control group 22 28 General medication treatment
Experimental group 26 24 Intelligent medical technology

Due to the tendency of patients to experience symptoms such as abdominal pain and bloating after eating, the patient was diagnosed with indigestion syndrome after professional examination. By analyzing the principles of organ diseases such as digestive system diseases and avoiding problems such as gastric cancer or gastrointestinal cancer, the control group was treated with ordinary drugs, while the experimental group was treated with intelligent medical technology. By observing the corresponding treatment, the control group and experimental group were analyzed and compared, and symptom scores were analyzed. Symptoms of indigestion include palpitations, vomiting, and abdominal distension. The score range was 1–9 points, with 1–3 points indicating no improvement or worsening of indigestion symptoms, 4–6 points indicating improvement of indigestion symptoms, and 7–9 points indicating disappearance of indigestion symptoms. Statistical Product and Service Solutions software was used to analyze and process the data, and standard deviation was used as the research indicator for analysis, with P < 0.05 indicating statistical significance.

4.2 Experimental results

4.2.1 Treatment success rate

One hundred patients with NDS were selected. By setting up an experimental group and a control group, data analysis was conducted on the symptoms of palpitations, vomiting, and abdominal distension among the patients. Due to the use of ordinary drugs in the control group and intelligent medical technology in the experimental group, the treatment plan for long-term severe gastrointestinal diseases can be determined by analyzing the treatment status of patients with NDS in these two groups. The comparative analysis of treatment success rates between the control group and the experimental group is shown in Table 2.

Table 2

Comparative analysis of treatment success rates between the control group and the experimental group

Observation indicators Cardiopalmus Vomit Abdominal distension Adverse reactions score
Control group 34% 45% 52% 5
Experimental group 42% 52% 60% 8
Statistical significance 0.03

Through the data analysis in Table 2, it was found that the success rate of treatment for palpitations in the control group was 34%, the success rate of treating vomiting symptoms was 45%, and the success rate of treating abdominal distension symptoms was 52%. The symptom score for adverse reactions to treatment was 5. After ordinary drug treatment, the symptoms of NDS in the control group of patients improved. The success rate of treating palpitations and vomiting symptoms in the experimental group was 42 and 52%, respectively; the success rate of treating abdominal distension symptoms was 60%, and the symptoms of NDS in the experimental group disappeared. By analyzing the data in Table 2, it is found that intelligent medical technology has a significant improvement effect on the treatment of symptoms of NDS in patients. Therefore, intelligent medical technology can play a role in eradicating symptoms of NDS and can be applied to clinical diagnosis and treatment.

4.2.2 Time

By observing the food residue in the digestive tract of patients in the control group and experimental group after eating, as well as the disappearance time of comprehensive symptoms of neurodyspepsia, the data of the two groups of experiments were compared. Because the control group of patients with digestive dysfunction was treated with ordinary drugs, detailed observation is needed. The patients in the experimental group used intelligent medical technology to treat diseases faster, so their symptoms improved significantly. Two sets of data were analyzed by comparing the time of symptom disappearance and the residual food in the digestive tract. The comparison of various observation indicators is shown in Table 3.

Table 3

Comparison of various observation indicators between the experimental group and the control group

Observation indicators Food residue Disappearance time
Cardiopalmus Vomit Abdominal distension
Control group 2.0 ml ± 0.2 ml 3.2 h ± 0.4 h 2.8 h ± 0.2 h 2.7 h ± 0.1 h
Experimental group 1.5 ml ± 0.1 ml 2.6 h ± 0.2 h 1.8 h ± 0.1 h 1.6 h ± 0.2 h
Statistical significance 0.001 0.001 0.001 0.001

According to the data in Table 3, the residual amount of gastrointestinal food in the control group was 2.0 ± 0.2 ml, while the residual amount of gastrointestinal food in the experimental group was 1.5 ± 0.1 ml. After analysis, it was found that the experimental group had better treatment effects on patients through intelligent medical technology, and the disappearance time of comprehensive symptoms of neurodyspepsia was also shorter. The disappearance time of palpitation symptoms in the experimental group was 0.8 h shorter than that in the control group. After adopting intelligent medical technology, the vomiting symptoms of patients were also significantly improved, and the time for symptom disappearance was reduced by 1.1 h; the disappearance time of symptoms of abdominal distension reaction was also reduced by 1 h. After data processing, it was found that the overall data analysis value was P = 0.001 < P = 0.05, so the data analysis results of this experiment had statistical significance.

4.2.3 Symptom points

According to the scoring principle of symptom integral values, the symptoms of male and female patients in both groups were scored, and the scorings of symptoms such as palpitations, vomiting, abdominal distension, and dizziness caused by indigestion were analyzed separately. The symptom score values are shown in Figure 3.

Figure 3 Symptom score values of the (a) control and (b) experimental groups.
Figure 3

Symptom score values of the (a) control and (b) experimental groups.

Figure 3a shows the symptom scores of the control group. According to Figure 3a, the overall symptom score of the control group was relatively low. Among them, the symptom score of male patients with palpitations was 5, the symptom score of vomiting was 6, the symptom score of abdominal distension was 5, and the symptom score for dizziness symptoms was 6; the symptom score for various symptoms in female patients was relatively low. Figure 3b shows the symptom scores of the experimental group. Through observation, it was found that the symptom score values of various indicators in male patients in the experimental group ranged from 8 to 9, while that of various indicators in female patients ranged from 7 to 9. Therefore, the integral value of symptoms of the experimental group treated with intelligent medical technology was higher, so intelligent medical technology can be applied to the clinical diagnosis and treatment of patients with comprehensive symptoms of neurodyspepsia.

4.2.4 Factor scoring

By investigating the daily living conditions of 100 patients and dividing them into 5 groups, the physical function and mental state of patients with NDS were studied, and the quality of life of the patients was analyzed to determine the main influencing factors of the patient’s illness. A percentage system was used for scoring. The higher the score, the better the quality of life, indicating that this influencing factor has a smaller impact on NDS. The scoring of influencing factors is shown in Figure 4.

Figure 4 Scoring of influencing factors in the (a) control and (b) experimental groups.
Figure 4

Scoring of influencing factors in the (a) control and (b) experimental groups.

Figure 4a shows the score of influencing factors in the control group, while Figure 4b shows the score of influencing factors in the experimental group. The questionnaire scores of patients with comprehensive symptoms of neurodyspepsia in the control group ranged from 55 to 65 for physical function and from 70 to 83 for mental state. Through data analysis, it can be seen that the quality of life of the control group patients was higher, while the quality of life of the experimental group was lower. Therefore, the symptoms of the control group patients were milder, while the symptoms of the experimental group patients were more severe. It can also be seen that the score of physical function was lower than that of the mental state, indicating that physical function indicators had a greater impact on patients, while mental state indicators had a smaller impact. Through analysis, it was found that the physical function score of the experimental group was 6.3% lower than that of the control group. Therefore, in daily life, more attention should be paid to physical health. Good habits should be maintained, and the occurrence of indigestion syndrome should be reduced.

Finally, in order to verify the diagnostic accuracy of intelligent medical technology and other scholars’ research methods in the diagnosis of neurodigestive syndrome, this article compares it with the method in literature 2 and tests the misdiagnosis and missed diagnosis rates of the two methods for different patient numbers. The results are shown in Figure 5.

Figure 5 Misdiagnosis and missed diagnosis rates under two methods: (a) in the experimental group and (b) in the control group.
Figure 5

Misdiagnosis and missed diagnosis rates under two methods: (a) in the experimental group and (b) in the control group.

It can be seen from Figure 5(a) and (b) that the highest misdiagnosis rate for patients in the experimental group using intelligent medical technology is 4%; the highest missed diagnosis rate is 6.67%; the control group of patients in the experimental literature 2 method had the highest misdiagnosis rate and missed diagnosis rate of 10%. The misdiagnosis rate and missed diagnosis rate of patients in the experimental group were significantly lower than those in the control group, and the difference was statistically significant (P < 0.05). This indicates that the use of intelligent medical technology can improve diagnostic accuracy, which is of great significance for preventing neurodigestive syndrome.

5 Conclusions

By studying the clinical diagnosis and treatment plans of intelligent medicine for NDS, this article analyzed the application of intelligent medical technology in clinical practice and found that the application of intelligent medical technology can bring great convenience to the medical field. Through experimental data analysis, it was found that patients with NDS can be treated through intelligent medical technology with good results. In the experiment, the factors affecting patients suffering from neurological dyspepsia syndrome were analyzed to come up with a prevention program that people should be aware of in their daily lives. Both physical and psychological factors can have an impact on the symptoms of indigestion syndrome in patients, and diagnosis and treatment should be based on actual conditions. When there are problems with the defense mechanism of the digestive system, patients generally experience symptoms such as palpitations, vomiting, bloating, and dizziness and are prone to various diseases, which should be treated promptly. The application of intelligent medicine in the clinical diagnosis of NDS studied in this article can provide significant references for the application of intelligent medicine in other medical fields.

  1. Funding information: Authors state no funding involved.

  2. Author contributions: J.Z. and W.M. designed the research study. L.L. and P.H. performed the research. Y.L. and W.Z. analyzed the data. J.Z., W.M., and X.Z. wrote the manuscript. All authors contributed to editorial changes in the manuscript. All authors read and approved the final manuscript.

  3. Conflict of interest: Authors state no conflict of interest.

  4. Data availability statement: The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Received: 2023-09-20
Revised: 2023-10-26
Accepted: 2023-11-14
Published Online: 2024-05-07

© 2024 the author(s), published by De Gruyter

This work is licensed under the Creative Commons Attribution 4.0 International License.

Articles in the same Issue

  1. Biomedical Sciences
  2. Constitutive and evoked release of ATP in adult mouse olfactory epithelium
  3. LARP1 knockdown inhibits cultured gastric carcinoma cell cycle progression and metastatic behavior
  4. PEGylated porcine–human recombinant uricase: A novel fusion protein with improved efficacy and safety for the treatment of hyperuricemia and renal complications
  5. Research progress on ocular complications caused by type 2 diabetes mellitus and the function of tears and blepharons
  6. The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway
  7. Brucella infection combined with Nocardia infection: A case report and literature review
  8. Detection of serum interleukin-18 level and neutrophil/lymphocyte ratio in patients with antineutrophil cytoplasmic antibody-associated vasculitis and its clinical significance
  9. Ang-1, Ang-2, and Tie2 are diagnostic biomarkers for Henoch-Schönlein purpura and pediatric-onset systemic lupus erythematous
  10. PTTG1 induces pancreatic cancer cell proliferation and promotes aerobic glycolysis by regulating c-myc
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  12. Effectiveness and safety of a mumps containing vaccine in preventing laboratory-confirmed mumps cases from 2002 to 2017: A meta-analysis
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  18. Current research and evidence gaps on placental development in iron deficiency anemia
  19. Single-nucleotide polymorphism rs2910829 in PDE4D is related to stroke susceptibility in Chinese populations: The results of a meta-analysis
  20. Pheochromocytoma-induced myocardial infarction: A case report
  21. Kaempferol regulates apoptosis and migration of neural stem cells to attenuate cerebral infarction by O‐GlcNAcylation of β-catenin
  22. Sirtuin 5 regulates acute myeloid leukemia cell viability and apoptosis by succinylation modification of glycine decarboxylase
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  24. KAT2A changes the function of endometrial stromal cells via regulating the succinylation of ENO1
  25. Current state of research on copper complexes in the treatment of breast cancer
  26. Exploring antioxidant strategies in the pathogenesis of ALS
  27. Helicobacter pylori causes gastric dysbacteriosis in chronic gastritis patients
  28. IL-33/soluble ST2 axis is associated with radiation-induced cardiac injury
  29. The predictive value of serum NLR, SII, and OPNI for lymph node metastasis in breast cancer patients with internal mammary lymph nodes after thoracoscopic surgery
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  35. Thymosin α1 combined with XELOX improves immune function and reduces serum tumor markers in colorectal cancer patients after radical surgery
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  207. Erratum to “Activation of hypermethylated P2RY1 mitigates gastric cancer by promoting apoptosis and inhibiting proliferation”
  208. Retraction
  209. Retraction to “MiR-223-3p regulates cell viability, migration, invasion, and apoptosis of non-small cell lung cancer cells by targeting RHOB”
  210. Retraction to “A data mining technique for detecting malignant mesothelioma cancer using multiple regression analysis”
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https://doi.org/10.1515/biol-2022-0802
Keywords for this article
intelligent medical treatment; neurodyspepsia syndrome; internet of things technology; clinical diagnosis
Creative Commons
BY 4.0

Articles in the same Issue

  1. Biomedical Sciences
  2. Constitutive and evoked release of ATP in adult mouse olfactory epithelium
  3. LARP1 knockdown inhibits cultured gastric carcinoma cell cycle progression and metastatic behavior
  4. PEGylated porcine–human recombinant uricase: A novel fusion protein with improved efficacy and safety for the treatment of hyperuricemia and renal complications
  5. Research progress on ocular complications caused by type 2 diabetes mellitus and the function of tears and blepharons
  6. The role and mechanism of esketamine in preventing and treating remifentanil-induced hyperalgesia based on the NMDA receptor–CaMKII pathway
  7. Brucella infection combined with Nocardia infection: A case report and literature review
  8. Detection of serum interleukin-18 level and neutrophil/lymphocyte ratio in patients with antineutrophil cytoplasmic antibody-associated vasculitis and its clinical significance
  9. Ang-1, Ang-2, and Tie2 are diagnostic biomarkers for Henoch-Schönlein purpura and pediatric-onset systemic lupus erythematous
  10. PTTG1 induces pancreatic cancer cell proliferation and promotes aerobic glycolysis by regulating c-myc
  11. Role of serum B-cell-activating factor and interleukin-17 as biomarkers in the classification of interstitial pneumonia with autoimmune features
  12. Effectiveness and safety of a mumps containing vaccine in preventing laboratory-confirmed mumps cases from 2002 to 2017: A meta-analysis
  13. Low levels of sex hormone-binding globulin predict an increased breast cancer risk and its underlying molecular mechanisms
  14. A case of Trousseau syndrome: Screening, detection and complication
  15. Application of the integrated airway humidification device enhances the humidification effect of the rabbit tracheotomy model
  16. Preparation of Cu2+/TA/HAP composite coating with anti-bacterial and osteogenic potential on 3D-printed porous Ti alloy scaffolds for orthopedic applications
  17. Aquaporin-8 promotes human dermal fibroblasts to counteract hydrogen peroxide-induced oxidative damage: A novel target for management of skin aging
  18. Current research and evidence gaps on placental development in iron deficiency anemia
  19. Single-nucleotide polymorphism rs2910829 in PDE4D is related to stroke susceptibility in Chinese populations: The results of a meta-analysis
  20. Pheochromocytoma-induced myocardial infarction: A case report
  21. Kaempferol regulates apoptosis and migration of neural stem cells to attenuate cerebral infarction by O‐GlcNAcylation of β-catenin
  22. Sirtuin 5 regulates acute myeloid leukemia cell viability and apoptosis by succinylation modification of glycine decarboxylase
  23. Apigenin 7-glucoside impedes hypoxia-induced malignant phenotypes of cervical cancer cells in a p16-dependent manner
  24. KAT2A changes the function of endometrial stromal cells via regulating the succinylation of ENO1
  25. Current state of research on copper complexes in the treatment of breast cancer
  26. Exploring antioxidant strategies in the pathogenesis of ALS
  27. Helicobacter pylori causes gastric dysbacteriosis in chronic gastritis patients
  28. IL-33/soluble ST2 axis is associated with radiation-induced cardiac injury
  29. The predictive value of serum NLR, SII, and OPNI for lymph node metastasis in breast cancer patients with internal mammary lymph nodes after thoracoscopic surgery
  30. Carrying SNP rs17506395 (T > G) in TP63 gene and CCR5Δ32 mutation associated with the occurrence of breast cancer in Burkina Faso
  31. P2X7 receptor: A receptor closely linked with sepsis-associated encephalopathy
  32. Probiotics for inflammatory bowel disease: Is there sufficient evidence?
  33. Identification of KDM4C as a gene conferring drug resistance in multiple myeloma
  34. Microbial perspective on the skin–gut axis and atopic dermatitis
  35. Thymosin α1 combined with XELOX improves immune function and reduces serum tumor markers in colorectal cancer patients after radical surgery
  36. Highly specific vaginal microbiome signature for gynecological cancers
  37. Sample size estimation for AQP4-IgG seropositive optic neuritis: Retinal damage detection by optical coherence tomography
  38. The effects of SDF-1 combined application with VEGF on femoral distraction osteogenesis in rats
  39. Fabrication and characterization of gold nanoparticles using alginate: In vitro and in vivo assessment of its administration effects with swimming exercise on diabetic rats
  40. Mitigating digestive disorders: Action mechanisms of Mediterranean herbal active compounds
  41. Distribution of CYP2D6 and CYP2C19 gene polymorphisms in Han and Uygur populations with breast cancer in Xinjiang, China
  42. VSP-2 attenuates secretion of inflammatory cytokines induced by LPS in BV2 cells by mediating the PPARγ/NF-κB signaling pathway
  43. Factors influencing spontaneous hypothermia after emergency trauma and the construction of a predictive model
  44. Long-term administration of morphine specifically alters the level of protein expression in different brain regions and affects the redox state
  45. Application of metagenomic next-generation sequencing technology in the etiological diagnosis of peritoneal dialysis-associated peritonitis
  46. Clinical diagnosis, prevention, and treatment of neurodyspepsia syndrome using intelligent medicine
  47. Case report: Successful bronchoscopic interventional treatment of endobronchial leiomyomas
  48. Preliminary investigation into the genetic etiology of short stature in children through whole exon sequencing of the core family
  49. Cystic adenomyoma of the uterus: Case report and literature review
  50. Mesoporous silica nanoparticles as a drug delivery mechanism
  51. Dynamic changes in autophagy activity in different degrees of pulmonary fibrosis in mice
  52. Vitamin D deficiency and inflammatory markers in type 2 diabetes: Big data insights
  53. Lactate-induced IGF1R protein lactylation promotes proliferation and metabolic reprogramming of lung cancer cells
  54. Meta-analysis on the efficacy of allogeneic hematopoietic stem cell transplantation to treat malignant lymphoma
  55. Mitochondrial DNA drives neuroinflammation through the cGAS-IFN signaling pathway in the spinal cord of neuropathic pain mice
  56. Application value of artificial intelligence algorithm-based magnetic resonance multi-sequence imaging in staging diagnosis of cervical cancer
  57. Embedded monitoring system and teaching of artificial intelligence online drug component recognition
  58. Investigation into the association of FNDC1 and ADAMTS12 gene expression with plumage coloration in Muscovy ducks
  59. Yak meat content in feed and its impact on the growth of rats
  60. A rare case of Richter transformation with breast involvement: A case report and literature review
  61. First report of Nocardia wallacei infection in an immunocompetent patient in Zhejiang province
  62. Rhodococcus equi and Brucella pulmonary mass in immunocompetent: A case report and literature review
  63. Downregulation of RIP3 ameliorates the left ventricular mechanics and function after myocardial infarction via modulating NF-κB/NLRP3 pathway
  64. Evaluation of the role of some non-enzymatic antioxidants among Iraqi patients with non-alcoholic fatty liver disease
  65. The role of Phafin proteins in cell signaling pathways and diseases
  66. Ten-year anemia as initial manifestation of Castleman disease in the abdominal cavity: A case report
  67. Coexistence of hereditary spherocytosis with SPTB P.Trp1150 gene variant and Gilbert syndrome: A case report and literature review
  68. Utilization of convolutional neural networks to analyze microscopic images for high-throughput screening of mesenchymal stem cells
  69. Exploratory evaluation supported by experimental and modeling approaches of Inula viscosa root extract as a potent corrosion inhibitor for mild steel in a 1 M HCl solution
  70. Imaging manifestations of ductal adenoma of the breast: A case report
  71. Gut microbiota and sleep: Interaction mechanisms and therapeutic prospects
  72. Isomangiferin promotes the migration and osteogenic differentiation of rat bone marrow mesenchymal stem cells
  73. Prognostic value and microenvironmental crosstalk of exosome-related signatures in human epidermal growth factor receptor 2 positive breast cancer
  74. Circular RNAs as potential biomarkers for male severe sepsis
  75. Knockdown of Stanniocalcin-1 inhibits growth and glycolysis in oral squamous cell carcinoma cells
  76. The expression and biological role of complement C1s in esophageal squamous cell carcinoma
  77. A novel GNAS mutation in pseudohypoparathyroidism type 1a with articular flexion deformity: A case report
  78. Predictive value of serum magnesium levels for prognosis in patients with non-small cell lung cancer undergoing EGFR-TKI therapy
  79. HSPB1 alleviates acute-on-chronic liver failure via the P53/Bax pathway
  80. IgG4-related disease complicated by PLA2R-associated membranous nephropathy: A case report
  81. Baculovirus-mediated endostatin and angiostatin activation of autophagy through the AMPK/AKT/mTOR pathway inhibits angiogenesis in hepatocellular carcinoma
  82. Metformin mitigates osteoarthritis progression by modulating the PI3K/AKT/mTOR signaling pathway and enhancing chondrocyte autophagy
  83. Evaluation of the activity of antimicrobial peptides against bacterial vaginosis
  84. Atypical presentation of γ/δ mycosis fungoides with an unusual phenotype and SOCS1 mutation
  85. Analysis of the microecological mechanism of diabetic kidney disease based on the theory of “gut–kidney axis”: A systematic review
  86. Omega-3 fatty acids prevent gestational diabetes mellitus via modulation of lipid metabolism
  87. Refractory hypertension complicated with Turner syndrome: A case report
  88. Interaction of ncRNAs and the PI3K/AKT/mTOR pathway: Implications for osteosarcoma
  89. Association of low attenuation area scores with pulmonary function and clinical prognosis in patients with chronic obstructive pulmonary disease
  90. Long non-coding RNAs in bone formation: Key regulators and therapeutic prospects
  91. The deubiquitinating enzyme USP35 regulates the stability of NRF2 protein
  92. Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as potential diagnostic markers for rebleeding in patients with esophagogastric variceal bleeding
  93. G protein-coupled receptor 1 participating in the mechanism of mediating gestational diabetes mellitus by phosphorylating the AKT pathway
  94. LL37-mtDNA regulates viability, apoptosis, inflammation, and autophagy in lipopolysaccharide-treated RLE-6TN cells by targeting Hsp90aa1
  95. The analgesic effect of paeoniflorin: A focused review
  96. Chemical composition’s effect on Solanum nigrum Linn.’s antioxidant capacity and erythrocyte protection: Bioactive components and molecular docking analysis
  97. Knockdown of HCK promotes HREC cell viability and inner blood–retinal barrier integrity by regulating the AMPK signaling pathway
  98. The role of rapamycin in the PINK1/Parkin signaling pathway in mitophagy in podocytes
  99. Laryngeal non-Hodgkin lymphoma: Report of four cases and review of the literature
  100. Clinical value of macrogenome next-generation sequencing on infections
  101. Overview of dendritic cells and related pathways in autoimmune uveitis
  102. TAK-242 alleviates diabetic cardiomyopathy via inhibiting pyroptosis and TLR4/CaMKII/NLRP3 pathway
  103. Hypomethylation in promoters of PGC-1α involved in exercise-driven skeletal muscular alterations in old age
  104. Profile and antimicrobial susceptibility patterns of bacteria isolated from effluents of Kolladiba and Debark hospitals
  105. The expression and clinical significance of syncytin-1 in serum exosomes of hepatocellular carcinoma patients
  106. A histomorphometric study to evaluate the therapeutic effects of biosynthesized silver nanoparticles on the kidneys infected with Plasmodium chabaudi
  107. PGRMC1 and PAQR4 are promising molecular targets for a rare subtype of ovarian cancer
  108. Analysis of MDA, SOD, TAOC, MNCV, SNCV, and TSS scores in patients with diabetes peripheral neuropathy
  109. SLIT3 deficiency promotes non-small cell lung cancer progression by modulating UBE2C/WNT signaling
  110. The relationship between TMCO1 and CALR in the pathological characteristics of prostate cancer and its effect on the metastasis of prostate cancer cells
  111. Heterogeneous nuclear ribonucleoprotein K is a potential target for enhancing the chemosensitivity of nasopharyngeal carcinoma
  112. PHB2 alleviates retinal pigment epithelium cell fibrosis by suppressing the AGE–RAGE pathway
  113. Anti-γ-aminobutyric acid-B receptor autoimmune encephalitis with syncope as the initial symptom: Case report and literature review
  114. Comparative analysis of chloroplast genome of Lonicera japonica cv. Damaohua
  115. Human umbilical cord mesenchymal stem cells regulate glutathione metabolism depending on the ERK–Nrf2–HO-1 signal pathway to repair phosphoramide mustard-induced ovarian cancer cells
  116. Electroacupuncture on GB acupoints improves osteoporosis via the estradiol–PI3K–Akt signaling pathway
  117. Renalase protects against podocyte injury by inhibiting oxidative stress and apoptosis in diabetic nephropathy
  118. Review: Dicranostigma leptopodum: A peculiar plant of Papaveraceae
  119. Combination effect of flavonoids attenuates lung cancer cell proliferation by inhibiting the STAT3 and FAK signaling pathway
  120. Renal microangiopathy and immune complex glomerulonephritis induced by anti-tumour agents: A case report
  121. Correlation analysis of AVPR1a and AVPR2 with abnormal water and sodium and potassium metabolism in rats
  122. Gastrointestinal health anti-diarrheal mixture relieves spleen deficiency-induced diarrhea through regulating gut microbiota
  123. Myriad factors and pathways influencing tumor radiotherapy resistance
  124. Exploring the effects of culture conditions on Yapsin (YPS) gene expression in Nakaseomyces glabratus
  125. Screening of prognostic core genes based on cell–cell interaction in the peripheral blood of patients with sepsis
  126. Coagulation factor II thrombin receptor as a promising biomarker in breast cancer management
  127. Ileocecal mucinous carcinoma misdiagnosed as incarcerated hernia: A case report
  128. Methyltransferase like 13 promotes malignant behaviors of bladder cancer cells through targeting PI3K/ATK signaling pathway
  129. The debate between electricity and heat, efficacy and safety of irreversible electroporation and radiofrequency ablation in the treatment of liver cancer: A meta-analysis
  130. ZAG promotes colorectal cancer cell proliferation and epithelial–mesenchymal transition by promoting lipid synthesis
  131. Baicalein inhibits NLRP3 inflammasome activation and mitigates placental inflammation and oxidative stress in gestational diabetes mellitus
  132. Impact of SWCNT-conjugated senna leaf extract on breast cancer cells: A potential apoptotic therapeutic strategy
  133. MFAP5 inhibits the malignant progression of endometrial cancer cells in vitro
  134. Major ozonated autohemotherapy promoted functional recovery following spinal cord injury in adult rats via the inhibition of oxidative stress and inflammation
  135. Axodendritic targeting of TAU and MAP2 and microtubule polarization in iPSC-derived versus SH-SY5Y-derived human neurons
  136. Differential expression of phosphoinositide 3-kinase/protein kinase B and Toll-like receptor/nuclear factor kappa B signaling pathways in experimental obesity Wistar rat model
  137. The therapeutic potential of targeting Oncostatin M and the interleukin-6 family in retinal diseases: A comprehensive review
  138. BA inhibits LPS-stimulated inflammatory response and apoptosis in human middle ear epithelial cells by regulating the Nf-Kb/Iκbα axis
  139. Role of circRMRP and circRPL27 in chronic obstructive pulmonary disease
  140. Investigating the role of hyperexpressed HCN1 in inducing myocardial infarction through activation of the NF-κB signaling pathway
  141. Characterization of phenolic compounds and evaluation of anti-diabetic potential in Cannabis sativa L. seeds: In vivo, in vitro, and in silico studies
  142. Quantitative immunohistochemistry analysis of breast Ki67 based on artificial intelligence
  143. Ecology and Environmental Science
  144. Screening of different growth conditions of Bacillus subtilis isolated from membrane-less microbial fuel cell toward antimicrobial activity profiling
  145. Degradation of a mixture of 13 polycyclic aromatic hydrocarbons by commercial effective microorganisms
  146. Evaluation of the impact of two citrus plants on the variation of Panonychus citri (Acari: Tetranychidae) and beneficial phytoseiid mites
  147. Prediction of present and future distribution areas of Juniperus drupacea Labill and determination of ethnobotany properties in Antalya Province, Türkiye
  148. Population genetics of Todarodes pacificus (Cephalopoda: Ommastrephidae) in the northwest Pacific Ocean via GBS sequencing
  149. A comparative analysis of dendrometric, macromorphological, and micromorphological characteristics of Pistacia atlantica subsp. atlantica and Pistacia terebinthus in the middle Atlas region of Morocco
  150. Macrofungal sporocarp community in the lichen Scots pine forests
  151. Assessing the proximate compositions of indigenous forage species in Yemen’s pastoral rangelands
  152. Food Science
  153. Gut microbiota changes associated with low-carbohydrate diet intervention for obesity
  154. Reexamination of Aspergillus cristatus phylogeny in dark tea: Characteristics of the mitochondrial genome
  155. Differences in the flavonoid composition of the leaves, fruits, and branches of mulberry are distinguished based on a plant metabolomics approach
  156. Investigating the impact of wet rendering (solventless method) on PUFA-rich oil from catfish (Clarias magur) viscera
  157. Non-linear associations between cardiovascular metabolic indices and metabolic-associated fatty liver disease: A cross-sectional study in the US population (2017–2020)
  158. Knockdown of USP7 alleviates atherosclerosis in ApoE-deficient mice by regulating EZH2 expression
  159. Utility of dairy microbiome as a tool for authentication and traceability
  160. Agriculture
  161. Enhancing faba bean (Vicia faba L.) productivity through establishing the area-specific fertilizer rate recommendation in southwest Ethiopia
  162. Impact of novel herbicide based on synthetic auxins and ALS inhibitor on weed control
  163. Perspectives of pteridophytes microbiome for bioremediation in agricultural applications
  164. Fertilizer application parameters for drip-irrigated peanut based on the fertilizer effect function established from a “3414” field trial
  165. Improving the productivity and profitability of maize (Zea mays L.) using optimum blended inorganic fertilization
  166. Application of leaf multispectral analyzer in comparison to hyperspectral device to assess the diversity of spectral reflectance indices in wheat genotypes
  167. Animal Sciences
  168. Knockdown of ANP32E inhibits colorectal cancer cell growth and glycolysis by regulating the AKT/mTOR pathway
  169. Development of a detection chip for major pathogenic drug-resistant genes and drug targets in bovine respiratory system diseases
  170. Exploration of the genetic influence of MYOT and MB genes on the plumage coloration of Muscovy ducks
  171. Transcriptome analysis of adipose tissue in grazing cattle: Identifying key regulators of fat metabolism
  172. Comparison of nutritional value of the wild and cultivated spiny loaches at three growth stages
  173. Transcriptomic analysis of liver immune response in Chinese spiny frog (Quasipaa spinosa) infected with Proteus mirabilis
  174. Disruption of BCAA degradation is a critical characteristic of diabetic cardiomyopathy revealed by integrated transcriptome and metabolome analysis
  175. Plant Sciences
  176. Effect of long-term in-row branch covering on soil microorganisms in pear orchards
  177. Photosynthetic physiological characteristics, growth performance, and element concentrations reveal the calcicole–calcifuge behaviors of three Camellia species
  178. Transcriptome analysis reveals the mechanism of NaHCO3 promoting tobacco leaf maturation
  179. Bioinformatics, expression analysis, and functional verification of allene oxide synthase gene HvnAOS1 and HvnAOS2 in qingke
  180. Water, nitrogen, and phosphorus coupling improves gray jujube fruit quality and yield
  181. Improving grape fruit quality through soil conditioner: Insights from RNA-seq analysis of Cabernet Sauvignon roots
  182. Role of Embinin in the reabsorption of nucleus pulposus in lumbar disc herniation: Promotion of nucleus pulposus neovascularization and apoptosis of nucleus pulposus cells
  183. Revealing the effects of amino acid, organic acid, and phytohormones on the germination of tomato seeds under salinity stress
  184. Combined effects of nitrogen fertilizer and biochar on the growth, yield, and quality of pepper
  185. Comprehensive phytochemical and toxicological analysis of Chenopodium ambrosioides (L.) fractions
  186. Impact of “3414” fertilization on the yield and quality of greenhouse tomatoes
  187. Exploring the coupling mode of water and fertilizer for improving growth, fruit quality, and yield of the pear in the arid region
  188. Metagenomic analysis of endophytic bacteria in seed potato (Solanum tuberosum)
  189. Antibacterial, antifungal, and phytochemical properties of Salsola kali ethanolic extract
  190. Exploring the hepatoprotective properties of citronellol: In vitro and in silico studies on ethanol-induced damage in HepG2 cells
  191. Enhanced osmotic dehydration of watermelon rind using honey–sucrose solutions: A study on pre-treatment efficacy and mass transfer kinetics
  192. Effects of exogenous 2,4-epibrassinolide on photosynthetic traits of 53 cowpea varieties under NaCl stress
  193. Comparative transcriptome analysis of maize (Zea mays L.) seedlings in response to copper stress
  194. An optimization method for measuring the stomata in cassava (Manihot esculenta Crantz) under multiple abiotic stresses
  195. Fosinopril inhibits Ang II-induced VSMC proliferation, phenotype transformation, migration, and oxidative stress through the TGF-β1/Smad signaling pathway
  196. Antioxidant and antimicrobial activities of Salsola imbricata methanolic extract and its phytochemical characterization
  197. Bioengineering and Biotechnology
  198. Absorbable calcium and phosphorus bioactive membranes promote bone marrow mesenchymal stem cells osteogenic differentiation for bone regeneration
  199. New advances in protein engineering for industrial applications: Key takeaways
  200. An overview of the production and use of Bacillus thuringiensis toxin
  201. Research progress of nanoparticles in diagnosis and treatment of hepatocellular carcinoma
  202. Bioelectrochemical biosensors for water quality assessment and wastewater monitoring
  203. PEI/MMNs@LNA-542 nanoparticles alleviate ICU-acquired weakness through targeted autophagy inhibition and mitochondrial protection
  204. Unleashing of cytotoxic effects of thymoquinone-bovine serum albumin nanoparticles on A549 lung cancer cells
  205. Erratum
  206. Erratum to “Investigating the association between dietary patterns and glycemic control among children and adolescents with T1DM”
  207. Erratum to “Activation of hypermethylated P2RY1 mitigates gastric cancer by promoting apoptosis and inhibiting proliferation”
  208. Retraction
  209. Retraction to “MiR-223-3p regulates cell viability, migration, invasion, and apoptosis of non-small cell lung cancer cells by targeting RHOB”
  210. Retraction to “A data mining technique for detecting malignant mesothelioma cancer using multiple regression analysis”
  211. Special Issue on Advances in Neurodegenerative Disease Research and Treatment
  212. Transplantation of human neural stem cell prevents symptomatic motor behavior disability in a rat model of Parkinson’s disease
  213. Special Issue on Multi-omics
  214. Inflammasome complex genes with clinical relevance suggest potential as therapeutic targets for anti-tumor drugs in clear cell renal cell carcinoma
  215. Gastroesophageal varices in primary biliary cholangitis with anti-centromere antibody positivity: Early onset?
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