Abstract
Foot orientation can be assessed in realtime by means of a foot-mounted inertial sensor. We consider a method that uses only accelerometer and gyroscope readings to calculate the foot pitch and roll angle, i.e. the foot orientation angle in the sagittal and frontal plane, respectively. Since magnetometers are avoided completely, the method can be used indoors as well as in the proximity of ferromagnetic material and magnetic disturbances. Furthermore, we allow for almost arbitrary mounting orientation in the sense that we only assume one of the local IMU coordinate axes to lie in the sagittal plane of the foot. The method is validated with respect to a conventional optical motion capture system in trials with transfemoral amputees walking with shoes and healthy subjects walking barefoot, both at different velocities. Root mean square deviations of less than 4° are found in all scenarios, while values near 2° are found in slow shoe walking. This demonstrates that the proposed method is suitable for realtime application such as the control of FES-based gait neuroprostheses and active orthoses.
1 Introduction
Foot motion assessment plays a central role in diagnosis and treatment of walking disabilities. Functional electrical stimulation (FES) and active orthoses represent effective tools for online gait support. Both technologies rely on realtime foot motion assessment. The conventional method for motion assessment is optical motion capture (OMC), which has the decisive disadvantage that it is not suitable for realtime applications. Furthermore, it is an expensive technology and strictly limiting in space and time, as it restricts the analysis to a laboratory environment. Ambulatory realtime motion capture can be performed by the use of inertial measurement units (IMU), which typically comprise accelerometers, gyroscopes, and magnetometers. They represent an inexpensive and easy-to-handle technology without any of the mentioned limitations of OMC. There are a number of standard methods that estimate the orientation of the foot based on measurement data of an IMU attached to the foot, see for example [1, 3, 7]. Since, in indoor environments, the magnetic field is often heavily disturbed and far from homogeneous, we consider an IMU-based method that completely avoids to use magnetometer readings to calculate pitch and roll angles. Furthermore, we allow for almost arbitrary mounting orientation in the sense that we only assume one of the local IMU coordinate axes to lie in the sagittal plane of the foot.
In this contribution, we focus on the question how accurate the obtained orientation measurements are with respect to the conventional OMC method under different walking conditions. Unlike most IMU validation studies, e.g. [1], we place the optical markers on anatomical landmarks instead of attaching them to the IMUs. Thereby, we compare the entire gait analysis methods instead of comparing only the measurement systems. In the following, we briefly explain the method, before we validate it in trials with transfemoral amputees walking with shoes and in trials with healthy subjects walking barefoot.
2 Methods
The measured angular rates and accelerations of the paretic foot are used to detect the gait eventstoe-off and initial contact, which mark the beginning and the end of the swing phase, as well as full contact and heel-rise, which mark the beginning and the end of thefoot-flat phase. In the following,tto,tic, tfc and thr will denote the according time instants of the considered step, respectively. As depicted in Figure 1, the period of time between heel-rise and toe-off is referred to aspre-swing, and the phase between initial contact and full contact is calledloading response. This is in accordance with standard literature, see e.g. [2]. The employed gait phase detection algorithm is described in [5] and, for the sake of brevity, is not further discussed here. Instead, we assume that we have realtime information of the current gait phase and consider the task of foot orientation angle measurement in the following.

Employed finite state automaton model (phases and transitions) of the gait cycle of one side. During foot-flat phase, the foot rests on the ground, while it has no ground contact during swing phase.

The angle α that the foot’s posterior-anterior axisxfoot and its projection into the horizontal plane (dotted lines) confine is a proper measure of foot pitch, while foot roll can be quantified analogously using the foot’s mediolateral axis yfoot. The local coordinate axes of the IMU are not parallel to any anatomical axis, but the local x-axis lies in the sagittal plane of the foot.
The foot’s pitch angle α and roll angle β are defined in Figure 2. The local(By ”local” we denote the coordinates in the moving sensor coordinate system.) coordinates of xfoot,yfoot ∈ ℝ3×1 are unknown because the sensor cannot be attached such that the local coordinate axes coincide with the anatomical axes of the foot, as Figure 3 illustrates. However, it is possible to assure that the local axis xlocal = (1, 0, 0)T of the IMU lies in the sagittal plane of the foot. We therefore assume that this is assured and determine the local coordinates of the foot’s posterior-anterior and mediolateral axis as follows: During every foot-flat phase, the local accelerometer readings a(t) are integrated over time, and the resulting vector is normalized to unit length:
where ‖·‖2 denotes the Euclidean norm. Since gravitational acceleration dominates when the foot is (almost) at rest, zff is (almost) vertical. Therefore, we calculate the local coordinates of the mediolateral axis yfoot as follows:
Likewise, we calculate the local coordinates of the posterior-anterior axis xfoot as follows:
Please note that, by construction, xfoot and yfoot are horizontal during stance and their local coordinates do not change with time, since the sensor moves along with the foot, see Figure 3 for illustration.
For each step, a strap-down integration [4] of the angular rates is started at heel-risethr that yields the rotation matrix Rff(t). This matrix transforms the local measurement vectors a(t) and g(t) of any time instantt between two foot-flat phases to the local coordinate system of the preceding foot-flat phase, which we refer to as the reference coordinate system of that step. By transforming xfoot to the reference coordinate system, in which the vertical axis zff is known, we calculate the time-dependent foot orientation angle in pitch direction:
Please note that the pitch angle is positive when the toes are above the heel and negative when vice versa. Likewise, we calculate the time-dependent foot orientation angle β in roll direction:
Due to the side-dependent axis definition (3), the roll angle β is always positive when the foot’s outer edge is above the inner edge, both for a right and a left foot.
However, it is important to note that orientation strap-down integration is always subject to drift, since, even with proper calibration, the gyroscopes have non-zero bias. Therefore, α(t) and β(t) also drift(For example, with the employed sensor hardware, we found that, at the end of a step, α(tfc) is typically in the range of 2°.) between each two foot-flat phases. At every full contact tfc, however, we can remove the drift from α(t), β(t) on the time interval t ∈ [thr,tfc] by assuming that neither the gyroscope bias nor the slope of the ground changed significantly during the swing phase:
In the following, we validate these IMU-based angles with respect to optical motion capture. Since the standard setup with only one optical marker on the forefoot and one on the ankle does not permit the calculation of roll orientation angles, we restrict the validation to foot pitch angles.
3 Experimental procedure and results of the validation

Experimental Setup with IMUs and optical markers attached to shoes and bare feet. Note that the data of the depicted IMUs on the shanks (upper photos) wasnot used in this study.
For evaluation of the proposed methods, the recorded data of two different experiments is processed. In both trial series, a wireless IMU was attached dorsally on the instep of each foot and optical markers of a visual motion capture system were attached to the lateral malleolus and the head of the fifth metatarsal (see Figure 3). In the first experiment, two healthy subjects walked barefoot at slow and fast pace, whereas in the second one, two transfemoral amputees walked with a leg prosthesis at self-assessed speed while wearing shoes on both the prosthetic and the contralateral foot. At least six trials were completed by each subject, for each of which the foot pitch angle is computed according to (6). For the sake of comparison, we also calculate the foot pitch from the three-dimensional optical marker positions.
Deviations between inertial and optical measurements. Columns show the walking velocity (vel.), the average root mean square error (RMSE) with its standard deviation with and without drift correction. Averages are taken over several steps. The rows refer to different subjects and their different footwear – barefoot (baref.), shoe and shoe on the prosthetic side (prosth.).
walking vel. | RMSE α [°] drift not removed | RMSE | |
Subj.1-shoe | 0.81 | 2.66 ± 0.73 | 2.24 ± 0.41 |
Subj.1-prosth. | 0.81 | 1.40 ± 0.21 | 1.20 ± 0.26 |
Subj.2-shoe | 1.42 | 5.78 ± 1.49 | 3.97 ± 0.51 |
Subj.2-prosth. | 1.42 | 3.97 ± 1.31 | 2.93 ± 0.75 |
Subj.3-baref. | 1.62 | 3.61 ± 0.87 | 3.63 ± 0.83 |
Subj.3-baref. | 0.85 | 3.14 ± 0.39 | 3.09 ± 0.36 |
Subj.4-baref. | 1.52 | 3.90 ± 0.91 | 3.79 ± 0.73 |
Subj.4-baref. | 0.78 | 3.37 ± 0.37 | 3.41 ± 0.31 |
The root mean square error (RMSE) with and without drift correction is determined for each trial of each subject. We then calculate the average and standard deviations over all trials for each foot. Table 1 shows the results, as well as corresponding walking velocities. In Figure 4a, the pitch angles of Subject 2 (cf. Table 1) are plotted over one step for both the prosthetic and the contralateral side. Furthermore, pitch angles for different walking velocities of the barefoot walking Subject 3 are presented in Figure 4b.
4 Discussion
We first analyze the influence of the footwear. It is evident that deviations between the results of both measurement systems are larger in barefoot trials than in trials with shoes. This is most likely due to slight deformations of the foot during stance-phase and push-off, which lead to relative motion of the IMU and the optical markers with respect to each other. Since the IMU was attached directly to the skin in the barefoot trials, the effect is stronger therein than in the shoe-trials, in which the shoe dampens this effect. Likewise, the data in Table 1 demonstrates that the deviations are slightly smaller on the prosthetic side, which is more rigid and allows for less relative motion of the markers and IMU with respect to each other.
If we furthermore compare RMSEs between the slow and fast trials of Subject 3 and 4, it is noticeable that the deviations are significantly smaller in slower walking. The same observation is also made when comparing (the prosthetic or contralateral foot of) Subject 1 and Subject 2, the latter of which walked at a much faster pace.

IMU-based foot pitch (solid) and reference angles (dashed) from an optical motion capture system. (a) for a prosthetic and a contralateral foot and in (b) for slow and fast walking. Plus markers indicate gait phase transitions (see Figure 1).
By applying the periodic online drift correction proposed in (9), the RMSE was reduced by more than 15% in the shoe-walkers. In the barefoot walkers, this correction had no significant effect.
5 Conclusion
A method for realtime foot pitch and roll angle estimation was considered that avoids magnetometers and copes with almost arbitrary mounting orientation. It was validated with respect to a conventional optical motion capture method in subjects with different footwear. Results indicate that deformations of the foot and shoe during foot-flat and push-off lead to relative motion of the optical markers and the IMUs with respect to each other, which are strongest in barefoot walking and weakest in prosthetic feet. Nevertheless, the deviation between inertial and optical measurements are in the few-degrees range under all tested conditions. For slow walking with shoes, accuracies below 2° were obtained.
With respect to the intended application in FES-based gait neuroprostheses and active orthoses, we conclude that the obtained deviations are small enough to facilitate precise feedback control of the foot motion.
Acknowledgment:
We would like to express our deep gratitude to Julius Thiele from TU Berlin as well as to Noelia Chia Bejarano and Simona Ferrante from Politecnico di Milano for providing the datasets that were analyzed in this study. Furthermore, we thank Sebastian Scheel and Dirk Reinhardt for their skillful support in automatic data evaluation.
Funding: Being conducted in the research project BeMobil, this work is funded by the German Federal Ministry of Research and Education (FKZ 16SV7069K).
Author’s Statement
Conflict of interest: Authors state no conflict of interest. Material and Methods: Informed consent: Informed consent has been obtained from all individuals included in this study. Ethical approval: The research related to human use has been complied with all the relevant national regulations, institutional policies and in accordance the tenets of the Helsinki Declaration, and has been approved by the authors’ institutional review board or equivalent committee.
References
[1] van den Noort JC, Ferrari A, Cutti AG, Becher JG, Harlaar J. Gait analysis in children with cerebral palsy via inertial and magnetic sensors. Med Biol Eng Comput 2013; 51:377–386.10.1007/s11517-012-1006-5Search in Google Scholar
[2] Perry J, Burnfield JM. Gait Analysis: Normal and Pathological Function. SLACK Incorporated 201010.1097/01241398-199211000-00023Search in Google Scholar
[3] Sabatini AM, Martelloni C, Scapellato S, Cavallo F. Assessment of walking features from foot inertial sensing. Biomedical Engineering 2005; 52(3): 486-49410.1109/TBME.2004.840727Search in Google Scholar
[4] Savage PG. Strapdown Inertial Navigation Integration Algorithm Design – Part 1: Attitude Algorithms. Journal of guidance, control, and dynamics 1998; 21(1):19–28.10.2514/2.4228Search in Google Scholar
[5] Seel T, Landgraf L, Schauer T. Online Gait Phase Detection with Automatic Adaption to Gait Velocity Changes Using Accelerometers and Gyroscopes. Biomedical Engineering / Biomedizinische Technik 2014; 59(S1):795–798.Search in Google Scholar
[6] Seel T, Raisch J, Schauer T. IMU-based joint angle measurement for gait analysis. Sensors 2014; 14(4):6891-909.10.3390/s140406891Search in Google Scholar
[7] Veltink PH, Slycke P, Hemssems J, Buschman R, Bulstra G, Her-mens H. Three dimensional intertial sensing of foot movements for automatic tuning of a two-channel implantable drop-foot stimulator. Medical Engineering & Physics 2003; 25(1): 21-28.10.1016/S1350-4533(02)00041-3Search in Google Scholar
© 2015 by Walter de Gruyter GmbH, Berlin/Boston
This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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- Three-dimensional anisotropic regularization for limited angle tomography
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- GPU-based real-time generation of large ultrasound volumes from freehand 3D sweeps
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- Experimental computer tomograph
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- US-tracked steered FUS in a respiratory ex vivo ovine liver phantom
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- Contribution of brownian rotation and particle assembly polarisation to the particle response in magnetic particle spectrometry
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- Preliminary investigations of magnetic modulated nanoparticles for microwave breast cancer detection
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- Construction of a device for magnetic separation of superparamagnetic iron oxide nanoparticles
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- An IHE-conform telecooperation platform supporting the treatment of dementia patients
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- Automated respiratory therapy system based on the ARDSNet protocol with systemic perfusion control
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- Identification of surgical instruments using UHF-RFID technology
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- A generic concept for the development of model-guided clinical decision support systems
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- Evaluation of local alterations in femoral bone mineral density measured via quantitative CT
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- Creating 3D gelatin phantoms for experimental evaluation in biomedicine
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- Influence of short-term fixation with mixed formalin or ethanol solution on the mechanical properties of human cortical bone
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- Analysis of the release kinetics of surface-bound proteins via laser-induced fluorescence
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- Tomographic particle image velocimetry of a water-jet for low volume harvesting of fat tissue for regenerative medicine
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- Wireless medical sensors – context, robustness and safety
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- Sequences for real-time magnetic particle imaging
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- Speckle-based off-axis holographic detection for non-contact photoacoustic tomography
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- A machine learning approach for planning valve-sparing aortic root reconstruction
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- An in-ear pulse wave velocity measurement system using heart sounds as time reference
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- Measuring different oxygenation levels in a blood perfusion model simulating the human head using NIRS
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- Multisegmental fusion of the lumbar spine a curse or a blessing?
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- Numerical analysis of the biomechanical complications accompanying the total hip replacement with NANOS-Prosthetic: bone remodelling and prosthesis migration
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- A muscle model for hybrid muscle activation
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- Mathematical, numerical and in-vitro investigation of cooling performance of an intra-carotid catheter for selective brain hypothermia
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- An ideally parameterized unscented Kalman filter for the inverse problem of electrocardiography
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- Interactive visualization of cardiac anatomy and atrial excitation for medical diagnosis and research
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- Virtualizing clinical cases of atrial flutter in a fast marching simulation including conduction velocity and ablation scars
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- Mesh structure-independent modeling of patient-specific atrial fiber orientation
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- Accelerating mono-domain cardiac electrophysiology simulations using OpenCL
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- Understanding the cellular mode of action of vernakalant using a computational model: answers and new questions
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- A java based simulator with user interface to simulate ventilated patients
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- Evaluation of an algorithm to choose between competing models of respiratory mechanics
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- Numerical simulation of low-pulsation gerotor pumps for use in the pharmaceutical industry and in biomedicine
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- Numerical and experimental flow analysis in centifluidic systems for rapid allergy screening tests
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- Biomechanical parameter determination of scaffold-free cartilage constructs (SFCCs) with the hyperelastic material models Yeoh, Ogden and Demiray
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- FPGA controlled artificial vascular system
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- Simulation based investigation of source-detector configurations for non-invasive fetal pulse oximetry
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- Test setup for characterizing the efficacy of embolic protection devices
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- Impact of electrode geometry on force generation during functional electrical stimulation
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- 3D-based visual physical activity assessment of children
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- Realtime assessment of foot orientation by Accelerometers and Gyroscopes
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- Image based reconstruction for cystoscopy
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- Image guided surgery innovation with graduate students - a new lecture format
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- Multichannel FES parameterization for controlling foot motion in paretic gait
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- Smartphone supported upper limb prosthesis
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- Use of quantitative tremor evaluation to enhance target selection during deep brain stimulation surgery for essential tremor
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- Evaluation of adhesion promoters for Parylene C on gold metallization
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- The influence of metallic ions from CoCr28Mo6 on the osteogenic differentiation and cytokine release of human osteoblasts
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- Increasing the visibility of thin NITINOL vascular implants
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- Possible reasons for early artificial bone failure in biomechanical tests of ankle arthrodesis systems
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- Development of a bending test procedure for the characterization of flexible ECoG electrode arrays
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- Tubular manipulators: a new concept for intracochlear positioning of an auditory prosthesis
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- Investigation of the dynamic diameter deformation of vascular stents during fatigue testing with radial loading
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- Electrospun vascular grafts with anti-kinking properties
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- Integration of temperature sensors in polyimide-based thin-film electrode arrays
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- Use cases and usability challenges for head-mounted displays in healthcare
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- Device- and service profiles for integrated or systems based on open standards
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- Risk management for medical devices in research projects
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- Simulation of varying femoral attachment sites of medial patellofemoral ligament using a musculoskeletal multi-body model
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- Does enhancing consciousness for strategic planning processes support the effectiveness of problem-based learning concepts in biomedical education?
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- SPIO processing in macrophages for MPI: The breast cancer MPI-SNLB-concept
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- Numerical simulations of airflow in the human pharynx of OSAHS patients