Home Feasibility of interactive gesture control of a robotic microscope
Article Open Access

Feasibility of interactive gesture control of a robotic microscope

  • Sven-Thomas Antoni EMAIL logo , Christian Sonnenburg , Thore Saathoff and Alexander Schlaefer
Published/Copyright: September 12, 2015

Abstract

Robotic devices become increasingly available in the clinics. One example are motorized surgical microscopes. While there are different scenarios on how to use the devices for autonomous tasks, simple and reliable interaction with the device is a key for acceptance by surgeons. We study, how gesture tracking can be integrated within the setup of a robotic microscope. In our setup, a Leap Motion Controller is used to track hand motion and adjust the field of view accordingly. We demonstrate with a survey that moving the field of view over a specified course is possible even for untrained subjects. Our results indicate that touch-less interaction with robots carrying small, near field gesture sensors is feasible and can be of use in clinical scenarios, where robotic devices are used in direct proximity of patient and physicians.

1 Introduction

Interaction with robotic assistance devices is particularly interesting in medical applications, where physicians are typically confronted with a number of different tools and instruments they need to control. One example are robotic cameras and microscopes. For example, operating microscopes are frequently used in neurosurgery, where the physician sits close to the patient’s head, looking at the surgical field through a microscope while performing precise surgery, e.g., along nerves. Given the small field of view, the clinical scenario typically involves frequent manual adjustments, i.e., grasping the handles and moving the microscope to the next region of interest. Clearly, removing the instruments from the surgical field, placing them outside and manually positioning the microscope interrupts the surgical workflow.

Different approaches for interaction and control of devices in the operating room (OR) have been proposed. Conventionally, switches and pedals are widely used for control, e.g., of patient couch and imaging systems. Limitations include the available space, complexity of the control, the degrees of freedom representable, and the need to maintain sterile surfaces. The latter is also an issue for touch interfaces. In contrast, voice control does not require changes in the clinical workflow [6, 8]. However, the results have been mixed, particularly with respect to robust and fail safe operation in an actual OR setting. In addition to voice control, switches, touch panels and pointers have been studied to realize interaction with devices [3, 6]. An approach that recently gained interest is gesture control [5, 9, 10]. Advantages include touch free interaction and simple integration.

While not widely used in clinical practice, a number of robotic surgical microscopes have been developed [2, 4, 7]. One possible use of these devices is to perform automated tasks like scanning resection cavities [1]. However, most of the time the microscope remains a tool in the hands of the physician, and improving the workflow has been another objective.

We consider gesture tracking for motion control of a robotic microscope. Using a Leap Motion camera (LMC) we present a setup illustrating how gesture tracking could be integrated. We studied the feasibility and precision to move the microscope using finger gestures. Our results indicate, that tracking and motion control are feasible.

2 System setup

We propose a setup where the sensor is embedded in a surgical microscope. A clear advantage is the unobstructed view on the surgical field. However, the sensor needs to be small, which holds true for the LMC. The device primarily consists of two cameras and three infrared light emitting diodes illuminating the scene. It is intended to track finger motion in a range of 25 to 600 mm above the device. Given that all processing is done on a computer, the device is small and lightweight, measuring just 75 mm by 25 mm by 6.2 mm. Another advantage is the high temporal resolution. The software interface provides information on hand gestures and can be configured to track different points, e.g., the centroid of the hand, or a finger.

Figure 1 Our experimental setup with a) microscopy robot, b) USB microscope, c) leap motion controller, d) hand phantom, e) hand motion robot, and f) track for manual motion experiments.
Figure 1

Our experimental setup with a) microscopy robot, b) USB microscope, c) leap motion controller, d) hand phantom, e) hand motion robot, and f) track for manual motion experiments.

To assess the feasibility of tracking and gesture control we have realized a simplified setup consisting of a UR5 (Universal Robots, Denmark) robotic arm, a USB microscope, and the leap motion controller. A second robot (ABB IRB120, Sweden) is used for some experiments evaluating the tracking performance by moving a hand phantom with adjustable fingers. A computer with an Xeon E3-1225v3 CPU and 16 GB RAM running Windows 8.1 Professional is used to process the LMC data and to control the UR5. Figure 1 shows the setup.

The LMC defines a coordinate frame with the x axis along the long centerline, the z axis along the short centerline, and the y axis normal to form a right hand system (see Fig. 2). For the purpose of our experiments, the height of the microscope with respect to the base plane was not changed. The LMC and the microscope were aligned and placed into an adapter and mounted to the tool flange such that the orientation of the coordinate axes was aligned. We did not need to obtain the actual transformation, i.e., particularly the translation, as all motions are relative to the last position of the microscope.

Figure 2 The LMC coordinate system.
Figure 2

The LMC coordinate system.

3 Experimental evaluation

In our analysis we were primarily interested in the possibility to track motion for interaction with a robotic microscope. We studied two different scenarios. First, the actual microscopy setup was used, but the motion was mimicked with the hand phantom mounted to a second robot (compare Fig. 1). Second, a pattern denoting a corridor for a target trajectory was printed, and 14 test persons were asked to move the center of the microscope image along the pattern. The center was highlighted by a cross-hair and the motion was solely controled by moving the hand.

In the first experiment, the trajectories of the robot representing the microscope and of the robot moving the hand are compared. This is evaluated by calculating the root mean squared error (RMSE)

(1)RMSE=j=1n(errj)2n

of the difference in the xy-plane between both TCP positions TCPposUR5 and TCPposIRB120

(2)errj=|((TCPposUR5)xy)j((TCPposIRB120)xy)j|2.

In the second experiment the quotient

(3)pquote=ΔoutsideΔtotal

between the total moved distance Δtotal and the distance Δoutside moved outside the course is calculated for evaluation. In addition the time of the subjects to finish the course is measured.

During the experiments the room temperature was constant at approximately 22 degrees Celsius and the LMC and the UR5 robot worked under normal operating conditions.

4 Results

4.1 Motion tracking

We measured the motion tracking performance for squares of edge length 50mm and 100mm at speeds ranging from 5mm/s to 20mm/s. An example of a resulting trajectory is shown in Fig. 3. The RMSE between the TCP positions is displayed in Table 1. The LMC was mounted with its longer centerline and hence its x-axis is parallel to the y-axis in the image. In the data this is represented by higher errors in y-direction of the example trajectory. Besides, the results are pretty straightforward with RMSE increasing for higher speeds and squares.

Figure 3 Example of the trajectories resulting from motion tracking. The square has an edge length of 50mm and the ABB moves at 5mm/s.
Figure 3

Example of the trajectories resulting from motion tracking. The square has an edge length of 50mm and the ABB moves at 5mm/s.

Table 1

RMSE of the motion tracking.

speed (mm/s)edge length (mm)RMSE (mm)
5506.8183
10506.9378
1010011.6893
20508.9277
2010013.9469

4.2 Microscope survey

The survey was completed by 14 untrained participants with one to three tries with the majority completing two tries. The results are displayed in Tab. 2. An example of a resulting trajectory is shown in Fig. 4. Clearly most of the subjects delivered very good results for not being familiar with the system before. Only two participants could not achieve comparable results. The data shows a pretty steep learning curve with most of the participants improving their results in a second run either in accuracy of their movement or in speed. In at least one try 9 of 13 achieved results of pquote < 0.1. As with motion tracking we achieved a sampling frequency greater than 100Hz.

5 Discussion

Our results indicate that the general tracking performance of the LMC using the standard software interface has to be carefully considered when using the device in clinical scenarios. The RMSE for robot hand motion was between 6.8mm and 13.9mm but some delay in the control is defi-nitely measured here, too. Following the course, most test persons performed well with 9 of 14 having a pquote below 0.1 in at least one try. The results for both, the robotic hand motion and the human trajectory following indicate that the errors are small enough to realize interactive motion control.

Figure 4 Course of the survey and an example of a trajectory with pquote = 0.085 and a runtime of 21.2s. While on the course the trajectory is green, when outside it is red. The start is denoted by a blue dot.
Figure 4

Course of the survey and an example of a trajectory with pquote = 0.085 and a runtime of 21.2s. While on the course the trajectory is green, when outside it is red. The start is denoted by a blue dot.

Table 2

Results of the different participants in the survey.

participanttrypquotetime (s)
subject 110.020761.2
2045.5
30.030021.0
subject 210.389137.9
20.127419.2
30.041520.5
subject 31031.6
2034.8
subject 410.039633.9
20.052645.2
30.052321.5
subject 510.171235.6
20.236840.0
subject 610.166639.4
subject 710.009474.8
20.023156.9
subject 810.069142.3
20.086238.3
subject 910.220625.9
20.164720.9
subject 1010.735834.4
20.564561.0
subject 1110.237943.2
20.240630.0
subject 1210.227387.8
20.096156.1
subject 1310.157825.9
20.031326.3
subject 1410.085021.2
20.009121.0
30.203112.3

Currently, few motorized microscopes are available, with their practical advantages being questionable. We have shown that interactive gesture control of a robotic microscope is feasible. Embedding the sensor in the device would avoid extra setup effort and line of sight problems while adding no extra complexity to the workflow.

Author’s Statement

  1. Conflict of interest: Authors state no conflict of interest. Material and Methods: Informed consent: Informed consent has been obtained from all individuals included in this study. Ethical approval: The conducted research is not related to either human or animals use.

References

[1] Finke, M., Kantelhardt, S., Schlaefer, A., Bruder, R., Lankenau, E., Giese, A., Schweikard, A.: Automatic scanning of large tissue areas in neurosurgery using optical coherence tomography. In: Int J Med Robot 8 (2012), Sep, Nr. 3, S. 327–33610.1002/rcs.1425Search in Google Scholar PubMed

[2] Finke, M., Schweikard, A.: Motorization of a surgical microscope for intra-operative navigation and intuitive control. In: Int J Med Robot 6 (2010), Sep, Nr. 3, S. 269–28010.1002/rcs.314Search in Google Scholar PubMed

[3] Finke, Markus, Stender, Birgit, Bruder, Ralf, Schlaefer, Alexander, Schweikard, Achim: An experimental comparison of control devices for automatic movements of a surgical microscope. In: Proceedings of the 24th International Conference and Exhibition on Computer Assisted Radiology and Surgery (CARS’10), 2010, S. 311–312Search in Google Scholar

[4] Giorgi, C., Eisenberg, H., Costi, G., Gallo, E., Garibotto, G., Casolino, D. S.: Robot-assisted microscope for neurosurgery. In: J Image Guid Surg 1 (1995), Nr. 3, S. 158–16310.1002/(SICI)1522-712X(1995)1:3<158::AID-IGS5>3.0.CO;2-9Search in Google Scholar

[5] Hartmann, Florian, Schlaefer, Alexander: Feasibility of touchless control of operating room lights. In: Int J Comput Assist Radiol Surg 8 (2013), Mar, Nr. 2, S. 259–26810.1007/s11548-012-0778-2Search in Google Scholar

[6] Kassell, N. F., Downs, JH 3rd, Graves, B. S.: Telepresence in neurosurgery: the integrated remote neurosurgical system. In: Stud Health Technol Inform 39 (1997), S. 411–419Search in Google Scholar

[7] Oppenlander, Mark E., Chowdhry, Shakeel A., Merkl, Brandon, Hattendorf, Guido M., Nakaji, Peter, Spetzler, Robert F.: Robotic autopositioning of the operating microscope. In: Neurosurgery 10 Suppl 2 (2014), Jun, S. 214–9; discussion 21910.1227/NEU.0000000000000276Search in Google Scholar PubMed

[8] Punt, Marius M., Stefels, Coen N., Grimbergen, Cornelis A., Dankelman, Jenny: Evaluation of voice control, touch panel control and assistant control during steering of an endoscope. In: Minim Invasive Ther Allied Technol 14 (2005), Nr. 3, S. 181– 18710.1080/13645700510033967Search in Google Scholar PubMed

[9] Rossol, Nathaniel, Cheng, Irene, Rui Shen, Basu, Anup: Touchfree medical interfaces. In: Conf Proc IEEE Eng Med Biol Soc 2014 (2014), S. 6597–660010.1109/EMBC.2014.6945140Search in Google Scholar PubMed

[10] Yoshimitsu, Kitaro, Muragaki, Yoshihiro, Maruyama, Takashi, Yamato, Masayuki, Iseki, Hiroshi: Development and initial clinical testing of ”OPECT”: an innovative device for fully intangible control of the intraoperative image-displaying monitor by the surgeon. In: Neurosurgery 10 Suppl 1 (2014), Mar, S. 46–50; discussion 5010.1227/NEU.0000000000000214Search in Google Scholar PubMed

Published Online: 2015-9-12
Published in Print: 2015-9-1

© 2015 by Walter de Gruyter GmbH, Berlin/Boston

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Articles in the same Issue

  1. Research Article
  2. Development and characterization of superparamagnetic coatings
  3. Research Article
  4. The development of an experimental setup to measure acousto-electric interaction signal
  5. Research Article
  6. Stability analysis of ferrofluids
  7. Research Article
  8. Investigation of endothelial growth using a sensors-integrated microfluidic system to simulate physiological barriers
  9. Research Article
  10. Energy harvesting for active implants: powering a ruminal pH-monitoring system
  11. Research Article
  12. New type of fluxgate magnetometer for the heart’s magnetic fields detection
  13. Research Article
  14. Field mapping of ballistic pressure pulse sources
  15. Research Article
  16. Development of a new homecare sleep monitor using body sounds and motion tracking
  17. Research Article
  18. Noise properties of textile, capacitive EEG electrodes
  19. Research Article
  20. Detecting phase singularities and rotor center trajectories based on the Hilbert transform of intraatrial electrograms in an atrial voxel model
  21. Research Article
  22. Spike sorting: the overlapping spikes challenge
  23. Research Article
  24. Separating the effect of respiration from the heart rate variability for cases of constant harmonic breathing
  25. Research Article
  26. Locating regions of arrhythmogenic substrate by analyzing the duration of triggered atrial activities
  27. Research Article
  28. Combining different ECG derived respiration tracking methods to create an optimal reconstruction of the breathing pattern
  29. Research Article
  30. Atrial and ventricular signal averaging electrocardiography in pacemaker and cardiac resynchronization therapy
  31. Research Article
  32. Estimation of a respiratory signal from a single-lead ECG using the 4th order central moments
  33. Research Article
  34. Compressed sensing of multi-lead ECG signals by compressive multiplexing
  35. Research Article
  36. Heart rate monitoring in ultra-high-field MRI using frequency information obtained from video signals of the human skin compared to electrocardiography and pulse oximetry
  37. Research Article
  38. Synchronization in wireless biomedical-sensor networks with Bluetooth Low Energy
  39. Research Article
  40. Automated classification of stages of anaesthesia by populations of evolutionary optimized fuzzy rules
  41. Research Article
  42. Effects of sampling rate on automated fatigue recognition in surface EMG signals
  43. Research Article
  44. Closed-loop transcranial alternating current stimulation of slow oscillations
  45. Research Article
  46. Cardiac index in atrio- and interventricular delay optimized cardiac resynchronization therapy and cardiac contractility modulation
  47. Research Article
  48. The role of expert evaluation for microsleep detection
  49. Research Article
  50. The impact of baseline wander removal techniques on the ST segment in simulated ischemic 12-lead ECGs
  51. Research Article
  52. Metal artifact reduction by projection replacements and non-local prior image integration
  53. Research Article
  54. A novel coaxial nozzle for in-process adjustment of electrospun scaffolds’ fiber diameter
  55. Research Article
  56. Processing of membranes for oxygenation using the Bellhouse-effect
  57. Research Article
  58. Inkjet printing of viable human dental follicle stem cells
  59. Research Article
  60. The use of an icebindingprotein out of the snowflea Hypogastrura harveyi as a cryoprotectant in the cryopreservation of mesenchymal stem cells
  61. Research Article
  62. New NIR spectroscopy based method to determine ischemia in vivo in liver – a first study on rats
  63. Research Article
  64. QRS and QT ventricular conduction times and permanent pacemaker therapy after transcatheter aortic valve implantation
  65. Research Article
  66. Adopting oculopressure tonometry as a transient in vivo rabbit glaucoma model
  67. Research Article
  68. Next-generation vision testing: the quick CSF
  69. Research Article
  70. Improving tactile sensation in laparoscopic surgery by overcoming size restrictions
  71. Research Article
  72. Design and control of a 3-DOF hydraulic driven surgical instrument
  73. Research Article
  74. Evaluation of endourological tools to improve the diagnosis and therapy of ureteral tumors – from model development to clinical application
  75. Research Article
  76. Frequency based assessment of surgical activities
  77. Research Article
  78. “Hands free for intervention”, a new approach for transoral endoscopic surgery
  79. Research Article
  80. Pseudo-haptic feedback in medical teleoperation
  81. Research Article
  82. Feasibility of interactive gesture control of a robotic microscope
  83. Research Article
  84. Towards structuring contextual information for workflow-driven surgical assistance functionalities
  85. Research Article
  86. Towards a framework for standardized semantic workflow modeling and management in the surgical domain
  87. Research Article
  88. Closed-loop approach for situation awareness of medical devices and operating room infrastructure
  89. Research Article
  90. Kinect based physiotherapy system for home use
  91. Research Article
  92. Evaluating the microsoft kinect skeleton joint tracking as a tool for home-based physiotherapy
  93. Research Article
  94. Integrating multimodal information for intraoperative assistance in neurosurgery
  95. Research Article
  96. Respiratory motion tracking using Microsoft’s Kinect v2 camera
  97. Research Article
  98. Using smart glasses for ultrasound diagnostics
  99. Research Article
  100. Measurement of needle susceptibility artifacts in magnetic resonance images
  101. Research Article
  102. Dimensionality reduction of medical image descriptors for multimodal image registration
  103. Research Article
  104. Experimental evaluation of different weighting schemes in magnetic particle imaging reconstruction
  105. Research Article
  106. Evaluation of CT capability for the detection of thin bone structures
  107. Research Article
  108. Towards contactless optical coherence elastography with acoustic tissue excitation
  109. Research Article
  110. Development and implementation of algorithms for automatic and robust measurement of the 2D:4D digit ratio using image data
  111. Research Article
  112. Automated high-throughput analysis of B cell spreading on immobilized antibodies with whole slide imaging
  113. Research Article
  114. Tissue segmentation from head MRI: a ground truth validation for feature-enhanced tracking
  115. Research Article
  116. Video tracking of swimming rodents on a reflective water surface
  117. Research Article
  118. MR imaging of model drug distribution in simulated vitreous
  119. Research Article
  120. Studying the extracellular contribution to the double wave vector diffusion-weighted signal
  121. Research Article
  122. Artifacts in field free line magnetic particle imaging in the presence of inhomogeneous and nonlinear magnetic fields
  123. Research Article
  124. Introducing a frequency-tunable magnetic particle spectrometer
  125. Research Article
  126. Imaging of aortic valve dynamics in 4D OCT
  127. Research Article
  128. Intravascular optical coherence tomography (OCT) as an additional tool for the assessment of stent structures
  129. Research Article
  130. Simple concept for a wide-field lensless digital holographic microscope using a laser diode
  131. Research Article
  132. Intraoperative identification of somato-sensory brain areas using optical imaging and standard RGB camera equipment – a feasibility study
  133. Research Article
  134. Respiratory surface motion measurement by Microsoft Kinect
  135. Research Article
  136. Improving image quality in EIT imaging by measurement of thorax excursion
  137. Research Article
  138. A clustering based dual model framework for EIT imaging: first experimental results
  139. Research Article
  140. Three-dimensional anisotropic regularization for limited angle tomography
  141. Research Article
  142. GPU-based real-time generation of large ultrasound volumes from freehand 3D sweeps
  143. Research Article
  144. Experimental computer tomograph
  145. Research Article
  146. US-tracked steered FUS in a respiratory ex vivo ovine liver phantom
  147. Research Article
  148. Contribution of brownian rotation and particle assembly polarisation to the particle response in magnetic particle spectrometry
  149. Research Article
  150. Preliminary investigations of magnetic modulated nanoparticles for microwave breast cancer detection
  151. Research Article
  152. Construction of a device for magnetic separation of superparamagnetic iron oxide nanoparticles
  153. Research Article
  154. An IHE-conform telecooperation platform supporting the treatment of dementia patients
  155. Research Article
  156. Automated respiratory therapy system based on the ARDSNet protocol with systemic perfusion control
  157. Research Article
  158. Identification of surgical instruments using UHF-RFID technology
  159. Research Article
  160. A generic concept for the development of model-guided clinical decision support systems
  161. Research Article
  162. Evaluation of local alterations in femoral bone mineral density measured via quantitative CT
  163. Research Article
  164. Creating 3D gelatin phantoms for experimental evaluation in biomedicine
  165. Research Article
  166. Influence of short-term fixation with mixed formalin or ethanol solution on the mechanical properties of human cortical bone
  167. Research Article
  168. Analysis of the release kinetics of surface-bound proteins via laser-induced fluorescence
  169. Research Article
  170. Tomographic particle image velocimetry of a water-jet for low volume harvesting of fat tissue for regenerative medicine
  171. Research Article
  172. Wireless medical sensors – context, robustness and safety
  173. Research Article
  174. Sequences for real-time magnetic particle imaging
  175. Research Article
  176. Speckle-based off-axis holographic detection for non-contact photoacoustic tomography
  177. Research Article
  178. A machine learning approach for planning valve-sparing aortic root reconstruction
  179. Research Article
  180. An in-ear pulse wave velocity measurement system using heart sounds as time reference
  181. Research Article
  182. Measuring different oxygenation levels in a blood perfusion model simulating the human head using NIRS
  183. Research Article
  184. Multisegmental fusion of the lumbar spine a curse or a blessing?
  185. Research Article
  186. Numerical analysis of the biomechanical complications accompanying the total hip replacement with NANOS-Prosthetic: bone remodelling and prosthesis migration
  187. Research Article
  188. A muscle model for hybrid muscle activation
  189. Research Article
  190. Mathematical, numerical and in-vitro investigation of cooling performance of an intra-carotid catheter for selective brain hypothermia
  191. Research Article
  192. An ideally parameterized unscented Kalman filter for the inverse problem of electrocardiography
  193. Research Article
  194. Interactive visualization of cardiac anatomy and atrial excitation for medical diagnosis and research
  195. Research Article
  196. Virtualizing clinical cases of atrial flutter in a fast marching simulation including conduction velocity and ablation scars
  197. Research Article
  198. Mesh structure-independent modeling of patient-specific atrial fiber orientation
  199. Research Article
  200. Accelerating mono-domain cardiac electrophysiology simulations using OpenCL
  201. Research Article
  202. Understanding the cellular mode of action of vernakalant using a computational model: answers and new questions
  203. Research Article
  204. A java based simulator with user interface to simulate ventilated patients
  205. Research Article
  206. Evaluation of an algorithm to choose between competing models of respiratory mechanics
  207. Research Article
  208. Numerical simulation of low-pulsation gerotor pumps for use in the pharmaceutical industry and in biomedicine
  209. Research Article
  210. Numerical and experimental flow analysis in centifluidic systems for rapid allergy screening tests
  211. Research Article
  212. Biomechanical parameter determination of scaffold-free cartilage constructs (SFCCs) with the hyperelastic material models Yeoh, Ogden and Demiray
  213. Research Article
  214. FPGA controlled artificial vascular system
  215. Research Article
  216. Simulation based investigation of source-detector configurations for non-invasive fetal pulse oximetry
  217. Research Article
  218. Test setup for characterizing the efficacy of embolic protection devices
  219. Research Article
  220. Impact of electrode geometry on force generation during functional electrical stimulation
  221. Research Article
  222. 3D-based visual physical activity assessment of children
  223. Research Article
  224. Realtime assessment of foot orientation by Accelerometers and Gyroscopes
  225. Research Article
  226. Image based reconstruction for cystoscopy
  227. Research Article
  228. Image guided surgery innovation with graduate students - a new lecture format
  229. Research Article
  230. Multichannel FES parameterization for controlling foot motion in paretic gait
  231. Research Article
  232. Smartphone supported upper limb prosthesis
  233. Research Article
  234. Use of quantitative tremor evaluation to enhance target selection during deep brain stimulation surgery for essential tremor
  235. Research Article
  236. Evaluation of adhesion promoters for Parylene C on gold metallization
  237. Research Article
  238. The influence of metallic ions from CoCr28Mo6 on the osteogenic differentiation and cytokine release of human osteoblasts
  239. Research Article
  240. Increasing the visibility of thin NITINOL vascular implants
  241. Research Article
  242. Possible reasons for early artificial bone failure in biomechanical tests of ankle arthrodesis systems
  243. Research Article
  244. Development of a bending test procedure for the characterization of flexible ECoG electrode arrays
  245. Research Article
  246. Tubular manipulators: a new concept for intracochlear positioning of an auditory prosthesis
  247. Research Article
  248. Investigation of the dynamic diameter deformation of vascular stents during fatigue testing with radial loading
  249. Research Article
  250. Electrospun vascular grafts with anti-kinking properties
  251. Research Article
  252. Integration of temperature sensors in polyimide-based thin-film electrode arrays
  253. Research Article
  254. Use cases and usability challenges for head-mounted displays in healthcare
  255. Research Article
  256. Device- and service profiles for integrated or systems based on open standards
  257. Research Article
  258. Risk management for medical devices in research projects
  259. Research Article
  260. Simulation of varying femoral attachment sites of medial patellofemoral ligament using a musculoskeletal multi-body model
  261. Research Article
  262. Does enhancing consciousness for strategic planning processes support the effectiveness of problem-based learning concepts in biomedical education?
  263. Research Article
  264. SPIO processing in macrophages for MPI: The breast cancer MPI-SNLB-concept
  265. Research Article
  266. Numerical simulations of airflow in the human pharynx of OSAHS patients
Downloaded on 7.9.2025 from https://www.degruyterbrill.com/document/doi/10.1515/cdbme-2015-0041/html
Scroll to top button