Abstract
Infrared thermography can be used as a pre-, intra- and post-operative imaging technique during medical treatment of patients. Modern infrared thermal cameras are capable of acquiring images with a high sensitivity of 10 mK and beyond. They provide a planar image of an examined 3D object in which this high sensitivity is only reached within a plane perpendicular to the camera axis and defined by the focus of the lens. Out of focus planes are blurred and temperature values are inaccurate. A new 3D infrared thermography system is built by combining a thermal camera with a depth camera. Multiple images at varying focal planes are acquired with the infrared camera using a motorized system. The sharp regions of individual images are projected onto the 3D object’s surface obtained by the depth camera. The system evaluation showed that deviation between measured temperature values and a ground truth is reduced with our system.
1 Introduction
Infrared thermography was introduced in the medical area already in the 1960s [1]. It is employed for diagnosis and monitoring of diseases involving temperature differences. Some applications are the detection of tumors [2], [3] or the monitoring of cardiovascular diseases [4], [5]. Moreover, because acquisition of data is performed contactless, thermography was brought in surgery for pre-operative planning, as intra-operative assistance tool and for post-operative monitoring of surgical outcome. Applications were mostly reported in neurosurgery [6], [7], [8] and in plastic surgery [9], [10]. Furthermore, since body temperature is correlated with tissue perfusion, identification and monitoring of skin transplants can be performed with this imaging technique [11], [12].
Recent technical developments apply thermal imaging onto 3D scenes for visualization purposes [13]. This technique was presented for medical applications too [14], [15], [16]. However, thermal cameras possess a very small depth of field, especially at small distances between camera and object [17]. Soldan [18] extended the depth of field by combining multiple thermal images of the same scene acquired with varying focuses. The optimal focus for an object is chosen by selecting a focus measure function (FMF). The FMF yields a minimum or maximum value at optimum. But good results require selecting an optimal FMF and it’s parameters for a given scene.
To overcome this disadvantage we combined an infrared thermal camera and a depth camera. The latter records a 3D surface of the examined object. Multiple thermal images of the scene are acquired with the infrared camera at varying focus settings. The optimal measurement is selected as a function of it’s depth in the 3D scene. Sharp parts of each thermal image are projected on the 3D object surface in order to reconstruct a sharp 3D thermal scene. An automatic focus control system was implemented with the future goal to use the device in the operating room.
2 3D thermographic imaging system
Then imaging system consisting of an infrared thermal camera Optris PI450 and a Microsoft Kinect V2, providing depth and visual information (Figure 1). The thermal camera has a spatial resolution of 382×288 pixels and a thermal sensitivity of 40 mK. The Kinect V2 provides a depth image with a spatial resolution of 512×424 pixels and a visual image of 1920×1080 pixels. The depth resolution is approximately 1 mm in a range of 0.5 m to 4 m.

The thermographic imaging system consists of a thermal camera and depth camera. A motor focus for the thermal camera allows for automatic image acquisition at different focal planes. A computer system processes the data.
The sharpness of the thermal image needs to be adjusted manually. To overcome this, we outfitted the camera with a drive for focus control. The hardware consists of a gear motor with a rotary encoder for position measurement which is controlled by an Arduino board. A firmware was developed providing basic functions for referencing the focus as well as getting and setting the focus position.
A software developed by us retrieves the temperature information and a depth image via provided vendor software. The thermal images are acquired using the Optris PI Connect which supplies the data for the inter-process communication via a dynamic link library. The Kinect for Windows SDK is used to acquire the depth and RGB images from the Kinect camera. After reconstructing the all-in-focus image, the 3D scene with applied thermal image mapping is rendered using the Kinect Fusion API.
2.1 Calibration of the system components
The components of the 3D thermographic imaging system must be calibrated in order to combine the different imaging modalities. The calibration process is described in detail in the following sections.
2.1.1 Calibration of the focus
Changing the focus of the thermal camera defines which objects at a certain distance to the camera will be displayed sharply. For automating the image acquisition process, the dependency between focus setting and the focal plane needs to be known. Therefore, the focus was referenced (zero position) by driving it to its end position. Following, the characteristic curve was determined by incrementally setting the focus and measuring the corresponding focal plane. The measurement was done by moving a checkerboard until it was displayed sharply and reading the corresponding object distance from the depth image.
2.1.2 Camera calibration
To be able to combine the spatial data of the depth camera and the temperature data of the thermal camera, the optical intrinsic (lens specific) and extrinsic parameters of the components must be calculated. For this process a known geometric pattern that is visible in both image modalities is needed. We used a checkerboard pattern which had alternating tiles removed (Figure 2). The removed tiles were clearly visible in both the depth and thermal image.

Checker board uses in the calibration process.
Firstly, the intrinsic parameters of the thermal camera were calculated. The intrinsic parameters of the depth camera are stored in its firmware. Secondly, the extrinsic parameters describing the spatial relation between the cameras were obtained. Using the resulting transformation matrix, the thermal image can projected onto the 3D scene retrieved by the depth camera.
2.2 Depth scanning
To improve the image quality, sharp parts of multiple thermal images are combined to an overall sharp image. Therefore, images at multiple focal planes are acquired. Points of the 3D surface acquired with the depth camera become the temperature value in the corresponding thermal image obtained using the transformation between thermal and depth images.
2.3 System evaluation
To evaluate the system an object which is visible in the depth and thermal data was constructed. We mounted LED stripes into grids onto a plane board. Three boards were positioned to focal planes at a distances of 500, 1000, 1500 mm. Each board contained 120 LEDs.
The current flowing through the LEDs causes heating which was used to evaluate the image quality. If the plane containing the LEDs is out of focus it gets blurred. This blurring leads to a reduced temperature of the LED measured in the thermal image. The LEDs were heated for half an hour to reach a steady state. Then a manually focused thermal image of each board was acquired. These images were used as a ground truth.
Secondly, our system reconstructed an overall sharp image using depth scanning (Figure 3). We calculated the temperature difference between the ground truth and our algorithm. If the correct focus setting corresponding to the thermal pixel was selected the temperature difference is expected to be zero. The depth scanning algorithm was compared to an image with the focus set to the middle board.

Reconstructed 3D scene with applied thermal map.
3 Results
When using depth scanning, the temperature deviation due to blurring is reduced (Table 1). The biggest improvement was achieved at near distance to the object. At far distances the negative effects of the small field of depth have less impact.
Temperature deviation due to blurring.
ΔT with depth scanning (K) | ΔT without depth scanning (K) | |||
---|---|---|---|---|
mean | std | mean | std | |
Board 1 (near) | −2.45 | 0.36 | −16.80 | 0.21 |
Board 2 (mid) | −0.56 | 0.19 | −0.36 | 0.13 |
Board 3 (far) | −1.31 | 0.24 | −5. 47 | 0.30 |
4 Discussion and conclusion
We showed that reconstructing an all-in-focus thermal image improves the image quality and therefor the accuracy of the temperature measurement. The temperature deviation induced by blurring was reduced but was still up to 2.45 K.
Remaining errors may be caused by the rather simple model used for the camera calibration. Adjusting the focus causes a change in the focal length parameter which was assumed fix. This dependency needs to be added to the calibration process.
[18] improved the image quality by calculating an all-in-focus thermal image by applying algorithms developed for visual images. This process requires adjusting parameters depending on the scene. By using a depth camera no parameters need to be adjusted, but more hardware is needed and the calibration process is more complex.
Further evaluation of the imaging system is needed to assess the impact on the image quality in medical use cases.
Author’s Statement
Research funding: Sponsored by the Federal Ministry of Education and Research. Conflict of interest: Authors state no conflict of interest. Material and methods: Informed consent: Informed consent is not applicable. Ethical approval: The conducted research is not related to either human or animal use.
References
[1] Ring EF, Ammer K. Infrared thermal imaging in medicine. Physiol Meas. 2012;33:R33–46.10.1088/0967-3334/33/3/R33Search in Google Scholar PubMed
[2] Gerasimova E, Audit B, Roux SG, Khalil A, Gileva O, Argoul F, et al. Wavelet-based multifractal analysis of dynamic infrared thermograms to assist in early breast cancer diagnosis. Front Physiol. 2014;5(Article 176):1–11.10.3389/fphys.2014.00176Search in Google Scholar PubMed PubMed Central
[3] Çetingül MP, Herman C. Quantification of the thermal signature of a melanoma lesion. Int J Therm Sci. 2011;50:421–31.10.1016/j.ijthermalsci.2010.10.019Search in Google Scholar
[4] Szentkuti A, Kavanagh HS, Grazio S. Infrared thermography and image analysis for biomedical use. Period Biol. 2011;113:385–92.Search in Google Scholar
[5] Jin C, Yang Y, Xue ZJ, Liu KM, Liu J. Automated analysis for screening knee osteoarthritis using medical infrared thermography. J Med Biol Eng. 2013;33:471–7.10.5405/jmbe.1054Search in Google Scholar
[6] Kateb B, Yamamoto V, Yu C, Grundfest W, Gruen JP. Infrared thermal imaging: a review of literature and case report. NeuroImage. 2009;47:T154–62.10.1016/j.neuroimage.2009.03.043Search in Google Scholar PubMed
[7] Steiner G, Sobottka SB, Koch E, Schackert G, Kirsch M. Intraoperative imaging of cortical cerebral perfusion by time-resolved thermography and multivariate data analysis. J Biomed Opt. 2011;16:1–6.10.1117/1.3528011Search in Google Scholar PubMed
[8] Rathmann P, Lindner D, Halama D, Chalopin C. Dynamische Infrarot-Thermographie (DIRT) zur Darstellung der Kopfhautdurchblutung bei neurochirurgischen Eingriffen, in Tagungsband der 14. Jahrestagung der Deutschen Gesellschaft für Computer und Roboterassistierte Chirurgie (CURAC), Bremen, 2015, pp. 17–19.Search in Google Scholar
[9] de Weerd L, Weum S, Mercer JB. The value of dynamic infrared thermography (DIRT) in perforatorselection and planning of free DIEP flaps. Ann Plast Surg. 2009;63:274–9.10.1097/SAP.0b013e318190321eSearch in Google Scholar
[10] Chubb DP, Taylor GI, Ashton MW. True and “Choke” anastomoses between perforator angiosomes: part II. Dynamic thermographic identification. Plast Reconstr Surg. 2013;132:1457–64.10.1097/01.prs.0000434407.73390.82Search in Google Scholar PubMed
[11] Lohman RF, Ozturk CN, Ozturk C, Jayaprakash V, Djohan R. An analysis of current techniques used for intraoperative flap evaluation. Ann Plast Surg. 2015;75:679–85.10.1097/SAP.0000000000000235Search in Google Scholar PubMed
[12] Just M, Chalopin C, Unger M, Halama D, Neumuth T, Dietz A, et al. Monitoring of microvascular free flaps following oropharyngeal reconstruction using infrared thermography: first clinical experiences. Eur Arch Otorhinolaryngol. 2015;273:1–9.10.1007/s00405-015-3780-9Search in Google Scholar PubMed
[13] Barone S, Paoli A, Razionale AV. A biomedical application combining visible and thermal 3D imaging. presented at the XVIII Congreso internactional de Ingenieria Grafica, Barcelona, 2006.Search in Google Scholar
[14] Spalding SJ, Kwoh CK, Boudreau R, Enama J, Lunich J, Huber D, et al. Three-dimensional and thermal surface imaging produces reliable measures of joint shape and temperature: a potential tool for quantifying arthritis. Arthritis Res Ther. 2008;10:R10.10.1186/ar2360Search in Google Scholar PubMed PubMed Central
[15] Grubisic I, Gjenero L, Lipic T, Sovic I, Skala T. Medical 3D thermography system. Period Biol. 2011;113:401–6.Search in Google Scholar
[16] Chen CY, Yeh CH, Chang BR, Pan JM. 3D reconstruction from IR thermal images and reprojective evaluations. Math Probl Eng. 2015;2015:8.10.1155/2015/520534Search in Google Scholar
[17] Schuster N, Franks J. Depth of field in modern thermal imaging. Presented at the SPIE Defense+ Security. International Society for Optics and Photonics, 2015, pp. 94520J–94520J–11.10.1117/12.2086937Search in Google Scholar
[18] Soldan S. On extended depth of field to improve the quality of automated thermographic measurements in unknown environments. Quant Infrared Thermogr J. 2012;9:135–50.10.1080/17686733.2012.738110Search in Google Scholar
©2016 Michael Unger et al., licensee De Gruyter.
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
Articles in the same Issue
- Synthesis and characterization of PIL/pNIPAAm hybrid hydrogels
- Novel blood protein based scaffolds for cardiovascular tissue engineering
- Cell adhesion and viability of human endothelial cells on electrospun polymer scaffolds
- Effects of heat treatment and welding process on superelastic behaviour and microstructure of micro electron beam welded NiTi
- Long-term stable modifications of silicone elastomer for improved hemocompatibility
- The effect of thermal treatment on the mechanical properties of PLLA tubular specimens
- Biocompatible wear-resistant thick ceramic coating
- Protection of active implant electronics with organosilicon open air plasma coating for plastic overmolding
- Examination of dielectric strength of thin Parylene C films under various conditions
- Open air plasma deposited antimicrobial SiOx/TiOx composite films for biomedical applications
- Systemic analysis about residual chloroform in PLLA films
- A macrophage model of osseointegration
- Towards in silico prognosis using big data
- Technical concept and evaluation of a novel shoulder simulator with adaptive muscle force generation and free motion
- Usability evaluation of a locomotor therapy device considering different strategies
- Hypoxia-on-a-chip
- Integration of a semi-automatic in-vitro RFA procedure into an experimental setup
- Fabrication of MEMS-based 3D-μECoG-MEAs
- High speed digital interfacing for a neural data acquisition system
- Bionic forceps for the handling of sensitive tissue
- Experimental studies on 3D printing of barium titanate ceramics for medical applications
- Patient specific root-analogue dental implants – additive manufacturing and finite element analysis
- 3D printing – a key technology for tailored biomedical cell culture lab ware
- 3D printing of hydrogels in a temperature controlled environment with high spatial resolution
- Biocompatibility of photopolymers for additive manufacturing
- Biochemical piezoresistive sensors based on pH- and glucose-sensitive hydrogels for medical applications
- Novel wireless measurement system of pressure dedicated to in vivo studies
- Portable auricular device for real-time swallow and chew detection
- Detection of miRNA using a surface plasmon resonance biosensor and antibody amplification
- Simulation and evaluation of stimulation scenarios for targeted vestibular nerve excitation
- Deep brain stimulation: increasing efficiency by alternative waveforms
- Prediction of immediately occurring microsleep events from brain electric signals
- Determining cardiac vagal threshold from short term heart rate complexity
- Classification of cardiac excitation patterns during atrial fibrillation
- An algorithm to automatically determine the cycle length coverage to identify rotational activity during atrial fibrillation – a simulation study
- Deriving respiration from high resolution 12-channel-ECG during cycling exercise
- Reducing of gradient induced artifacts on the ECG signal during MRI examinations using Wilcoxon filter
- Automatic detection and mapping of double potentials in intracardiac electrograms
- Modeling the pelvic region for non-invasive pelvic intraoperative neuromonitoring
- Postprocessing algorithm for automated analysis of pelvic intraoperative neuromonitoring signals
- Best practice: surgeon driven application in pelvic operations
- Vasomotor assessment by camera-based photoplethysmography
- Classification of morphologic changes in photoplethysmographic waveforms
- Novel computation of pulse transit time from multi-channel PPG signals by wavelet transform
- Efficient design of FIR filter based low-pass differentiators for biomedical signal processing
- Nonlinear causal influences assessed by mutual compression entropy
- Comparative study of methods for solving the correspondence problem in EMD applications
- fNIRS for future use in auditory diagnostics
- Semi-automated detection of fractional shortening in zebrafish embryo heart videos
- Blood pressure measurement on the cheek
- Derivation of the respiratory rate from directly and indirectly measured respiratory signals using autocorrelation
- Left cardiac atrioventricular delay and inter-ventricular delay in cardiac resynchronization therapy responder and non-responder
- An automatic systolic peak detector of blood pressure waveforms using 4th order cumulants
- Real-time QRS detection using integrated variance for ECG gated cardiac MRI
- Preprocessing of unipolar signals acquired by a novel intracardiac mapping system
- In-vitro experiments to characterize ventricular electromechanics
- Continuous non-invasive monitoring of blood pressure in the operating room: a cuffless optical technology at the fingertip
- Application of microwave sensor technology in cardiovascular disease for plaque detection
- Artificial blood circulatory and special Ultrasound Doppler probes for detecting and sizing gaseous embolism
- Detection of microsleep events in a car driving simulation study using electrocardiographic features
- A method to determine the kink resistance of stents and stent delivery systems according to international standards
- Comparison of stented bifurcation and straight vessel 3D-simulation with a prior simulated velocity profile inlet
- Transient Euler-Lagrange/DEM simulation of stent thrombosis
- Automated control of the laser welding process of heart valve scaffolds
- Automation of a test bench for accessing the bendability of electrospun vascular grafts
- Influence of storage conditions on the release of growth factors in platelet-rich blood derivatives
- Cryopreservation of cells using defined serum-free cryoprotective agents
- New bioreactor vessel for tissue engineering of human nasal septal chondrocytes
- Determination of the membrane hydraulic permeability of MSCs
- Climate retainment in carbon dioxide incubators
- Multiple factors influencing OR ventilation system effectiveness
- Evaluation of an app-based stress protocol
- Medication process in Styrian hospitals
- Control tower to surgical theater
- Development of a skull phantom for the assessment of implant X-ray visibility
- Surgical navigation with QR codes
- Investigation of the pressure gradient of embolic protection devices
- Computer assistance in femoral derotation osteotomy: a bottom-up approach
- Automatic depth scanning system for 3D infrared thermography
- A service for monitoring the quality of intraoperative cone beam CT images
- Resectoscope with an easy to use twist mechanism for improved handling
- In vitro simulation of distribution processes following intramuscular injection
- Adjusting inkjet printhead parameters to deposit drugs into micro-sized reservoirs
- A flexible standalone system with integrated sensor feedback for multi-pad electrode FES of the hand
- Smart control for functional electrical stimulation with optimal pulse intensity
- Tactile display on the remaining hand for unilateral hand amputees
- Effects of sustained electrical stimulation on spasticity assessed by the pendulum test
- An improved tracking framework for ultrasound probe localization in image-guided radiosurgery
- Improvement of a subviral particle tracker by the use of a LAP-Kalman-algorithm
- Learning discriminative classification models for grading anal intraepithelial neoplasia
- Regularization of EIT reconstruction based on multi-scales wavelet transforms
- Assessing MRI susceptibility artefact through an indicator of image distortion
- EyeGuidance – a computer controlled system to guide eye movements
- A framework for feedback-based segmentation of 3D image stacks
- Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear
- 3D Local in vivo Environment (LivE) imaging for single cell protein analysis of bone tissue
- Inside-Out access strategy using new trans-vascular catheter approach
- US/MRI fusion with new optical tracking and marker approach for interventional procedures inside the MRI suite
- Impact of different registration methods in MEG source analysis
- 3D segmentation of thyroid ultrasound images using active contours
- Designing a compact MRI motion phantom
- Cerebral cortex classification by conditional random fields applied to intraoperative thermal imaging
- Classification of indirect immunofluorescence images using thresholded local binary count features
- Analysis of muscle fatigue conditions using time-frequency images and GLCM features
- Numerical evaluation of image parameters of ETR-1
- Fabrication of a compliant phantom of the human aortic arch for use in Particle Image Velocimetry (PIV) experimentation
- Effect of the number of electrodes on the reconstructed lung shape in electrical impedance tomography
- Hardware dependencies of GPU-accelerated beamformer performances for microwave breast cancer detection
- Computer assisted assessment of progressing osteoradionecrosis of the jaw for clinical diagnosis and treatment
- Evaluation of reconstruction parameters of electrical impedance tomography on aorta detection during saline bolus injection
- Evaluation of open-source software for the lung segmentation
- Automatic determination of lung features of CF patients in CT scans
- Image analysis of self-organized multicellular patterns
- Effect of key parameters on synthesis of superparamagnetic nanoparticles (SPIONs)
- Radiopacity assessment of neurovascular implants
- Development of a desiccant based dielectric for monitoring humidity conditions in miniaturized hermetic implantable packages
- Development of an artifact-free aneurysm clip
- Enhancing the regeneration of bone defects by alkalizing the peri-implant zone – an in vitro approach
- Rapid prototyping of replica knee implants for in vitro testing
- Protecting ultra- and hyperhydrophilic implant surfaces in dry state from loss of wettability
- Advanced wettability analysis of implant surfaces
- Patient-specific hip prostheses designed by surgeons
- Plasma treatment on novel carbon fiber reinforced PEEK cages to enhance bioactivity
- Wear of a total intervertebral disc prosthesis
- Digital health and digital biomarkers – enabling value chains on health data
- Usability in the lifecycle of medical software development
- Influence of different test gases in a non-destructive 100% quality control system for medical devices
- Device development guided by user satisfaction survey on auricular vagus nerve stimulation
- Empirical assessment of the time course of innovation in biomedical engineering: first results of a comparative approach
- Effect of left atrial hypertrophy on P-wave morphology in a computational model
- Simulation of intracardiac electrograms around acute ablation lesions
- Parametrization of activation based cardiac electrophysiology models using bidomain model simulations
- Assessment of nasal resistance using computational fluid dynamics
- Resistance in a non-linear autoregressive model of pulmonary mechanics
- Inspiratory and expiratory elastance in a non-linear autoregressive model of pulmonary mechanics
- Determination of regional lung function in cystic fibrosis using electrical impedance tomography
- Development of parietal bone surrogates for parietal graft lift training
- Numerical simulation of mechanically stimulated bone remodelling
- Conversion of engineering stresses to Cauchy stresses in tensile and compression tests of thermoplastic polymers
- Numerical examinations of simplified spondylodesis models concerning energy absorption in magnetic resonance imaging
- Principle study on the signal connection at transabdominal fetal pulse oximetry
- Influence of Siluron® insertion on model drug distribution in the simulated vitreous body
- Evaluating different approaches to identify a three parameter gas exchange model
- Effects of fibrosis on the extracellular potential based on 3D reconstructions from histological sections of heart tissue
- From imaging to hemodynamics – how reconstruction kernels influence the blood flow predictions in intracranial aneurysms
- Flow optimised design of a novel point-of-care diagnostic device for the detection of disease specific biomarkers
- Improved FPGA controlled artificial vascular system for plethysmographic measurements
- Minimally spaced electrode positions for multi-functional chest sensors: ECG and respiratory signal estimation
- Automated detection of alveolar arches for nasoalveolar molding in cleft lip and palate treatment
- Control scheme selection in human-machine- interfaces by analysis of activity signals
- Event-based sampling for reducing communication load in realtime human motion analysis by wireless inertial sensor networks
- Automatic pairing of inertial sensors to lower limb segments – a plug-and-play approach
- Contactless respiratory monitoring system for magnetic resonance imaging applications using a laser range sensor
- Interactive monitoring system for visual respiratory biofeedback
- Development of a low-cost senor based aid for visually impaired people
- Patient assistive system for the shoulder joint
- A passive beating heart setup for interventional cardiology training
Articles in the same Issue
- Synthesis and characterization of PIL/pNIPAAm hybrid hydrogels
- Novel blood protein based scaffolds for cardiovascular tissue engineering
- Cell adhesion and viability of human endothelial cells on electrospun polymer scaffolds
- Effects of heat treatment and welding process on superelastic behaviour and microstructure of micro electron beam welded NiTi
- Long-term stable modifications of silicone elastomer for improved hemocompatibility
- The effect of thermal treatment on the mechanical properties of PLLA tubular specimens
- Biocompatible wear-resistant thick ceramic coating
- Protection of active implant electronics with organosilicon open air plasma coating for plastic overmolding
- Examination of dielectric strength of thin Parylene C films under various conditions
- Open air plasma deposited antimicrobial SiOx/TiOx composite films for biomedical applications
- Systemic analysis about residual chloroform in PLLA films
- A macrophage model of osseointegration
- Towards in silico prognosis using big data
- Technical concept and evaluation of a novel shoulder simulator with adaptive muscle force generation and free motion
- Usability evaluation of a locomotor therapy device considering different strategies
- Hypoxia-on-a-chip
- Integration of a semi-automatic in-vitro RFA procedure into an experimental setup
- Fabrication of MEMS-based 3D-μECoG-MEAs
- High speed digital interfacing for a neural data acquisition system
- Bionic forceps for the handling of sensitive tissue
- Experimental studies on 3D printing of barium titanate ceramics for medical applications
- Patient specific root-analogue dental implants – additive manufacturing and finite element analysis
- 3D printing – a key technology for tailored biomedical cell culture lab ware
- 3D printing of hydrogels in a temperature controlled environment with high spatial resolution
- Biocompatibility of photopolymers for additive manufacturing
- Biochemical piezoresistive sensors based on pH- and glucose-sensitive hydrogels for medical applications
- Novel wireless measurement system of pressure dedicated to in vivo studies
- Portable auricular device for real-time swallow and chew detection
- Detection of miRNA using a surface plasmon resonance biosensor and antibody amplification
- Simulation and evaluation of stimulation scenarios for targeted vestibular nerve excitation
- Deep brain stimulation: increasing efficiency by alternative waveforms
- Prediction of immediately occurring microsleep events from brain electric signals
- Determining cardiac vagal threshold from short term heart rate complexity
- Classification of cardiac excitation patterns during atrial fibrillation
- An algorithm to automatically determine the cycle length coverage to identify rotational activity during atrial fibrillation – a simulation study
- Deriving respiration from high resolution 12-channel-ECG during cycling exercise
- Reducing of gradient induced artifacts on the ECG signal during MRI examinations using Wilcoxon filter
- Automatic detection and mapping of double potentials in intracardiac electrograms
- Modeling the pelvic region for non-invasive pelvic intraoperative neuromonitoring
- Postprocessing algorithm for automated analysis of pelvic intraoperative neuromonitoring signals
- Best practice: surgeon driven application in pelvic operations
- Vasomotor assessment by camera-based photoplethysmography
- Classification of morphologic changes in photoplethysmographic waveforms
- Novel computation of pulse transit time from multi-channel PPG signals by wavelet transform
- Efficient design of FIR filter based low-pass differentiators for biomedical signal processing
- Nonlinear causal influences assessed by mutual compression entropy
- Comparative study of methods for solving the correspondence problem in EMD applications
- fNIRS for future use in auditory diagnostics
- Semi-automated detection of fractional shortening in zebrafish embryo heart videos
- Blood pressure measurement on the cheek
- Derivation of the respiratory rate from directly and indirectly measured respiratory signals using autocorrelation
- Left cardiac atrioventricular delay and inter-ventricular delay in cardiac resynchronization therapy responder and non-responder
- An automatic systolic peak detector of blood pressure waveforms using 4th order cumulants
- Real-time QRS detection using integrated variance for ECG gated cardiac MRI
- Preprocessing of unipolar signals acquired by a novel intracardiac mapping system
- In-vitro experiments to characterize ventricular electromechanics
- Continuous non-invasive monitoring of blood pressure in the operating room: a cuffless optical technology at the fingertip
- Application of microwave sensor technology in cardiovascular disease for plaque detection
- Artificial blood circulatory and special Ultrasound Doppler probes for detecting and sizing gaseous embolism
- Detection of microsleep events in a car driving simulation study using electrocardiographic features
- A method to determine the kink resistance of stents and stent delivery systems according to international standards
- Comparison of stented bifurcation and straight vessel 3D-simulation with a prior simulated velocity profile inlet
- Transient Euler-Lagrange/DEM simulation of stent thrombosis
- Automated control of the laser welding process of heart valve scaffolds
- Automation of a test bench for accessing the bendability of electrospun vascular grafts
- Influence of storage conditions on the release of growth factors in platelet-rich blood derivatives
- Cryopreservation of cells using defined serum-free cryoprotective agents
- New bioreactor vessel for tissue engineering of human nasal septal chondrocytes
- Determination of the membrane hydraulic permeability of MSCs
- Climate retainment in carbon dioxide incubators
- Multiple factors influencing OR ventilation system effectiveness
- Evaluation of an app-based stress protocol
- Medication process in Styrian hospitals
- Control tower to surgical theater
- Development of a skull phantom for the assessment of implant X-ray visibility
- Surgical navigation with QR codes
- Investigation of the pressure gradient of embolic protection devices
- Computer assistance in femoral derotation osteotomy: a bottom-up approach
- Automatic depth scanning system for 3D infrared thermography
- A service for monitoring the quality of intraoperative cone beam CT images
- Resectoscope with an easy to use twist mechanism for improved handling
- In vitro simulation of distribution processes following intramuscular injection
- Adjusting inkjet printhead parameters to deposit drugs into micro-sized reservoirs
- A flexible standalone system with integrated sensor feedback for multi-pad electrode FES of the hand
- Smart control for functional electrical stimulation with optimal pulse intensity
- Tactile display on the remaining hand for unilateral hand amputees
- Effects of sustained electrical stimulation on spasticity assessed by the pendulum test
- An improved tracking framework for ultrasound probe localization in image-guided radiosurgery
- Improvement of a subviral particle tracker by the use of a LAP-Kalman-algorithm
- Learning discriminative classification models for grading anal intraepithelial neoplasia
- Regularization of EIT reconstruction based on multi-scales wavelet transforms
- Assessing MRI susceptibility artefact through an indicator of image distortion
- EyeGuidance – a computer controlled system to guide eye movements
- A framework for feedback-based segmentation of 3D image stacks
- Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear
- 3D Local in vivo Environment (LivE) imaging for single cell protein analysis of bone tissue
- Inside-Out access strategy using new trans-vascular catheter approach
- US/MRI fusion with new optical tracking and marker approach for interventional procedures inside the MRI suite
- Impact of different registration methods in MEG source analysis
- 3D segmentation of thyroid ultrasound images using active contours
- Designing a compact MRI motion phantom
- Cerebral cortex classification by conditional random fields applied to intraoperative thermal imaging
- Classification of indirect immunofluorescence images using thresholded local binary count features
- Analysis of muscle fatigue conditions using time-frequency images and GLCM features
- Numerical evaluation of image parameters of ETR-1
- Fabrication of a compliant phantom of the human aortic arch for use in Particle Image Velocimetry (PIV) experimentation
- Effect of the number of electrodes on the reconstructed lung shape in electrical impedance tomography
- Hardware dependencies of GPU-accelerated beamformer performances for microwave breast cancer detection
- Computer assisted assessment of progressing osteoradionecrosis of the jaw for clinical diagnosis and treatment
- Evaluation of reconstruction parameters of electrical impedance tomography on aorta detection during saline bolus injection
- Evaluation of open-source software for the lung segmentation
- Automatic determination of lung features of CF patients in CT scans
- Image analysis of self-organized multicellular patterns
- Effect of key parameters on synthesis of superparamagnetic nanoparticles (SPIONs)
- Radiopacity assessment of neurovascular implants
- Development of a desiccant based dielectric for monitoring humidity conditions in miniaturized hermetic implantable packages
- Development of an artifact-free aneurysm clip
- Enhancing the regeneration of bone defects by alkalizing the peri-implant zone – an in vitro approach
- Rapid prototyping of replica knee implants for in vitro testing
- Protecting ultra- and hyperhydrophilic implant surfaces in dry state from loss of wettability
- Advanced wettability analysis of implant surfaces
- Patient-specific hip prostheses designed by surgeons
- Plasma treatment on novel carbon fiber reinforced PEEK cages to enhance bioactivity
- Wear of a total intervertebral disc prosthesis
- Digital health and digital biomarkers – enabling value chains on health data
- Usability in the lifecycle of medical software development
- Influence of different test gases in a non-destructive 100% quality control system for medical devices
- Device development guided by user satisfaction survey on auricular vagus nerve stimulation
- Empirical assessment of the time course of innovation in biomedical engineering: first results of a comparative approach
- Effect of left atrial hypertrophy on P-wave morphology in a computational model
- Simulation of intracardiac electrograms around acute ablation lesions
- Parametrization of activation based cardiac electrophysiology models using bidomain model simulations
- Assessment of nasal resistance using computational fluid dynamics
- Resistance in a non-linear autoregressive model of pulmonary mechanics
- Inspiratory and expiratory elastance in a non-linear autoregressive model of pulmonary mechanics
- Determination of regional lung function in cystic fibrosis using electrical impedance tomography
- Development of parietal bone surrogates for parietal graft lift training
- Numerical simulation of mechanically stimulated bone remodelling
- Conversion of engineering stresses to Cauchy stresses in tensile and compression tests of thermoplastic polymers
- Numerical examinations of simplified spondylodesis models concerning energy absorption in magnetic resonance imaging
- Principle study on the signal connection at transabdominal fetal pulse oximetry
- Influence of Siluron® insertion on model drug distribution in the simulated vitreous body
- Evaluating different approaches to identify a three parameter gas exchange model
- Effects of fibrosis on the extracellular potential based on 3D reconstructions from histological sections of heart tissue
- From imaging to hemodynamics – how reconstruction kernels influence the blood flow predictions in intracranial aneurysms
- Flow optimised design of a novel point-of-care diagnostic device for the detection of disease specific biomarkers
- Improved FPGA controlled artificial vascular system for plethysmographic measurements
- Minimally spaced electrode positions for multi-functional chest sensors: ECG and respiratory signal estimation
- Automated detection of alveolar arches for nasoalveolar molding in cleft lip and palate treatment
- Control scheme selection in human-machine- interfaces by analysis of activity signals
- Event-based sampling for reducing communication load in realtime human motion analysis by wireless inertial sensor networks
- Automatic pairing of inertial sensors to lower limb segments – a plug-and-play approach
- Contactless respiratory monitoring system for magnetic resonance imaging applications using a laser range sensor
- Interactive monitoring system for visual respiratory biofeedback
- Development of a low-cost senor based aid for visually impaired people
- Patient assistive system for the shoulder joint
- A passive beating heart setup for interventional cardiology training