Mizaj assessment in multiple sclerosis patients based on Persian Medicine

Reza Abbasian; Morteza Mojahedi; Mostafa Alizadeh; Soraya Khafri; Mohammad Ansaripour; Abdolali Moosavyzadeh; Mohammadali Kamali; Mahmoud Babaeian; Hossein Sourtiji; Vahid Shaygannejad; Hossein Kerdarian; Hossein Rezaeizadeh

doi:10.1515/jcim-2020-0428

Article

Mizaj assessment in multiple sclerosis patients based on Persian Medicine

Reza Abbasian , Morteza Mojahedi , Mostafa Alizadeh , Soraya Khafri , Mohammad Ansaripour , Abdolali Moosavyzadeh , Mohammadali Kamali , Mahmoud Babaeian , Hossein Sourtiji , Vahid Shaygannejad , Hossein Kerdarian and Hossein Rezaeizadeh

Published/Copyright: May 10, 2021

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From the journal Journal of Complementary and Integrative Medicine Volume 19 Issue 2

Abstract

Objectives

Increased incidence of multiple sclerosis (MS) calls for supporting complementary therapies in this field. Persian Medicine (PM) specialists present various assumptions to help patients through Mizaj (temperament) modification, but its confirmation requires scientific evidence. This study aimed at identifying the Mizaj of MS patients, and comparing it with their Mizaj before the onset of the disease, and with that of healthy people.

Methods

Forty-two MS and fifty-four healthy subjects participated in the study as case and control groups. General and brain Mizaj in patients were identified by five PM specialists before and after the onset of the disease. Mojahedi Mizaj Questionnaire (MMQ) was completed by the two groups. The validity of MMQ was assessed using Mizaj diagnosis by PM specialists as the gold standard. t-test, McNemar-Bowker, Wilcoxon, and Chi-square (χ ²) tests were used to compare the Mizaj of patients before and after the onset of the disease, and between the two groups (p<0.05).

Results

The sensitivity and specificity of MMQ for Hotness (75, 81%) and Coldness (75, 65%) were acceptable. There were no significant differences between patients and healthy subjects in terms of general Mizaj. But general and brain Mizaj of patients after developing MS inclined to coldness and dryness, although merely inclination of general Mizaj to coldness was significant (p=0.03).

Conclusions

According to our results, the Mizaj of MS patients has an inclination toward coldness and dryness; Also, MMQ can be used as a validated scale for identifying the Mizaj of MS patients in future studies.

Keywords: brain Mizaj; lifestyle; Mizaj; multiple sclerosis; Persian Medicine; personalized medicine

Corresponding author: Morteza Mojahedi, MD, PhD, Traditional Medicine and History of Medical Sciences Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran; and Department of History of Medical Sciences, School of Persian Medicine, Babol University of Medical Sciences, Babol, Iran, E-mail mortazamojahedy@gmail.com

Acknowledgments

This study is part of Reza Abbasian’s thesis for Master of Science in Occupational Therapy, performed at the Faculty of Rehabilitation Sciences, Isfahan University of Medical Sciences. Hereby, the authors would like to express their sincere thanks to the Occupational Therapy Department of the Faculty of Rehabilitation Sciences of Isfahan and the staff of the MS clinic of Ayatollah Kashani and Al-Zahra Hospitals who have contributed to improve the quality of the study. As well as Mohammad Aghalari to editing English form of Article.

Research funding: None declared.
Author contributions: R.A: concept and design of study, data acquisition, manuscript editing, Final approval of the version to be published. M.M: PM specialist for participants Mizaj identification, data acquisition, concept and design of study, manuscript editing and manuscript review, Final approval of the version to be published. M.A: data analysis, literature search, manuscript preparation, manuscript editing, Final approval of the version to be published. S.kh: data analysis, statistical analysis, manuscript editing, Final approval of the version to be published. M.A: PM specialist for participants Mizaj identification, data acquisition, manuscript editing and manuscript review, Final approval of the version to be published. A.A. M: PM specialist for participants Mizaj identification, data acquisition, manuscript editing, Final approval of the version to be published. M.K: PM specialist for participants Mizaj identification, data acquisition, manuscript editing, Final approval. M.B: PM specialist for participants Mizaj identification, data acquisition, manuscript editing, Final approval. H.S: data acquisition, manuscript editing and manuscript review, Final approval. V.Sh.: Visit of patients and MS diagnosis (neurologist), Final approval of the version to be published. H.K: literature search, manuscript preparation. H.R: manuscript editing and manuscript review, Final approval of the version to be published. All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
Competing interest: There are no conflicts of interest.
Informed consent: Not applicable.
Ethical approval: Not applicable.

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Received: 2020-08-11

Accepted: 2021-02-17

Published Online: 2021-05-10

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Articles in the same Issue

https://doi.org/10.1515/jcim-2020-0428

Keywords for this article

brain Mizaj; lifestyle; Mizaj; multiple sclerosis; Persian Medicine; personalized medicine