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Tackling NCDs in the WHO European Region: accelerating progress toward 2030 and beyond

  • Allison Ekberg EMAIL logo , Ivo Rakovac , Kremlin Wickramsinghe , Carina Ferreira-Borges , Angela Ciobanu , Clare Farrand , Jill Farrington and Gauden Galea
Published/Copyright: September 5, 2025

Abstract

Noncommunicable diseases and mental health conditions are leading causes of ill health in the WHO European Region. This September leaders will gather at the UN to assess progress toward global targets and to agree on a political declaration. Accelerating progress requires commitment and action at all levels – local to global. It requires raising NCDs and mental health on political agendas, implementing and enforcing proven policies, and advancing a fundamental shift toward multisectoral approaches.

Zusammenfassung

Nichtübertragbare Krankheiten und psychische Erkrankungen sind in der Europäischen Region der WHO die häufigsten Ursachen für gesundheitliche Probleme. Im September werden Staats- und Regierungschefs bei den Vereinten Nationen zusammenkommen, um die Fortschritte im Hinblick auf die Verwirklichung der globalen Zielvorgaben zu bewerten und sich auf eine politische Erklärung zu einigen. Zur Beschleunigung der Fortschritte bedarf es Engagement und konkretes Handeln auf allen Ebenen – von der kommunalen bis zur globalen Ebene. Dazu ist es erforderlich, nichtübertragbaren Krankheiten und psychischer Gesundheit einen höheren Stellenwert auf den politischen Tagesordnungen einzuräumen, bewährte Maßnahmen um- und durchzusetzen und einen grundlegenden Wandel hin zu ressortübergreifenden Ansätzen voranzutreiben.

Noncommunicable diseases and mental health conditions are the main causes of ill health in the WHO European Region. This September global leaders will gather in New York for the 4th UN High-Level Meeting on the prevention and control of noncommunicable diseases to take stock of progress toward global targets to reduce the burden of NCDs and to agree on a new political declaration for the last five years of the Sustainable Development Goals (SDG) era.

Across the WHO European Region, progress toward the Global NCD targets and SDGs is faltering and uneven. At the global level it is estimated that without increased implementation of proven and effective interventions half of all countries will fail to meet the SDG target 3.4 to reduce NCD-related premature mortality by one-third between 2010-2030 [1].

While the WHO European Region was on track to achieve this target, the Covid-19 pandemic derailed progress. In 2021 NCDs caused 2.3 million premature deaths (death between 30 – 69 years) in the region, many of which are avoidable [2]. New analysis by the WHO Regional Office for Europe found that NCDs cause 1.8 million avoidable deaths annually, 60% of which are preventable with effective public health measures and 40% of which are treatable with appropriate healthcare services. The preventable deaths can be attributed to a handful of modifiable risk factors including tobacco and alcohol use, unhealthy diets, insufficient physical activity, overweight and obesity, and raised blood pressure, lipids, and glucose, and air pollution.

Unless we accelerate implementation and enforcement of the WHO NCD best buys, our Region will have the highest tobacco use prevalence among all WHO Regions by 2030. In 2022, 179 million adults in the European Region—more than 25% of the population—were current tobacco users. Among adolescents aged 13–15, the figure stands at 4 million [3]. People over the age of 15 years in our Region are already the highest per capita alcohol drinkers in the world. Among youth, one in four deaths is alcohol-related—often the result of injury, violence, or accident. Obesity continues to rise and physical inactivity remains unacceptably high. Cardiovascular disease remains the leading cause of death in the region, hypertension is the leading risk and excessive salt intake is a key modifiable risk factor [4]. Deaths from cancer comprise 40% of avoidable deaths [2].

But there is reason for hope. Ten countries in the Region have achieved the European Program of Work target for premature mortality reduction ahead of schedule (25% reduction between 2010 and 2025) and 26 are on track to do so this year. They are succeeding through addressing both preventable and treatable mortality, through reducing exposure to risk factors, and investing in management and delivery of care. For example, an integrated approach of salt reduction strategies and hypertension control in PHC can make a difference.

Despite their established effectiveness, implementation and enforcement of the WHO NCD best buys has been uneven and disappointing. This has been attributed to the false perception that the benefits take too long to realize and are therefore not attractive to policymakers. WHO Europe experts conducted a systematic review of the best buys and other recommended interventions, to identify 25 NCD quick buys–interventions that demonstrate public health impact in less than five years (Table 1) [5]. These findings offer guidance to policymakers by identifying effective interventions that both align with political cycles as well as the 2030 SDG goal of reducing premature mortality from NCDs. A key task for the WHO European Region over the next five years is to accelerate implementation and enforcement of these policies. Investment NCD surveillance and monitoring to assess progress is also essential.

Table 1:

NCD quick buys [5].

Risk Factor/Disease Quick buy intervention Evidence of earliest possible effect on UN-linked target
Tobacco (5) Eliminate exposure to second-hand tobacco smoke in all indoor workplaces, public places, public transport <1 year
Increase excise taxes and prices on tobacco products <1 year
Provision of cost-covered effective pharmacological interventions to all tobacco users who want to quit through the use of nicotine replacement therapy (NRT), Bupropion and Verenicline <1 year
Implement large graphic health warnings on all tobacco packages, accompanied by plain/standardized packaging 14 months
Enact and enforce comprehensive bans on tobacco advertising, promotion and sponsorship 2 years
Alcohol (4) Increase excise taxes on alcoholic beverages <1 year
Enact and enforce bans or comprehensive restrictions on exposure to alcohol advertising (across multiple types of media) <1 year
Enact and enforce restrictions on the physical availability of retailed alcohol (via reduced hours of sale) <1 year
Provide brief psychosocial intervention for persons with hazardous and harmful alcohol use 1 year
Unhealthy Diet (3) Front-of-pack labelling as part of comprehensive nutrition labelling policies for facilitating consumers’ understanding and choice of food for healthy diets <1 year
Reformulation policies for healthier food and beverage products (e.g. elimination of trans-fatty acids and/or reduction of saturated fats, free sugars and/or sodium) 1 year
Behaviour change communication and mass media campaigns for healthy diets (e.g. to reduce the intake of energy, free sugars, sodium, and unhealthy fats, and to increase the consumption of legumes, whole grains, fruits and vegetables) 3 years
Physical Activity (1) Brief counselling intervention on physical activity in primary health care <1 year
Cardiovascular Diseases (3) Pharmacological treatment of hypertension in adults using either of the following: thiazide and thiazide-like agents; angiotensin converting enzyme inhibitors (ACE-Is)/ angiotensin-receptor blocker (ARBs); calcium channel blockers (CCBs) <1 year
Treatment new cases of acute myocardial infarction with acetylsalicylic acid initially treated in a hospital setting with follow up carried out through primary health care facilities at a 95% coverage rate; Treatment new cases of acute myocardial infarction with acetylsalicylic acid and thrombolysis, with patients initially treated in a hospital setting with follow up carried out through primary health care facilities at a 95% coverage rate; Treatment of new cases of acute myocardial infarction with acetylsalicylic acid, thrombolysis and clopidogrel, with patients initially treated in a hospital setting with follow up carried out through primary health care facilities at a 95% coverage rate <1 year
Treatment of acute ischemic stroke with intravenous thrombolytic therapy <1 year
Diabetes (4) Glycaemic control for people with diabetes, along with standard home glucose monitoring for people treated with insulin to reduce diabetes complications <1 year
Statin use in people with diabetes >40 years old <1 year
Control of blood pressure in people with diabetes 1 year
Screening of people with diabetes for albuminuria and treatment with angiotensin-converting enzyme inhibitor for the prevention and delay of renal disease <4.5 years
Chronic Respiratory Diseases (1) Acute treatment of COPD exacerbations with inhaled bronchodilators and oral steroids <1 year
Cancer (4) Vaccination against human papillomavirus (1-2 doses) of 9–14 year old girls <1 year
Cervical cancer: HPV DNA screening, starting at the age of 30 years with regular screening every 5 to 10 years (using a screen-and-treat approach or screen, triage and treat approach) <1 year
Cervical cancer: early diagnosis programs linked with timely diagnostic work-up and comprehensive cancer treatment <1 year
Breast cancer: early diagnosis programs linked with timely diagnostic work-up and comprehensive cancer treatment <1 year

When mandatory and government-led, these policies save lives. A recent study by the WHO Regional Office for Europe found that taxation and availability measures –both quick buys—decreased all-cause mortality and increased life expectancy in the Baltic states [5]. Moreover, increasing excise taxes can bring in additional state revenue, which in turn can offset some of the economic costs incurred by the use of these harmful products or be used for other purposes by governments. While taxation of alcohol and tobacco is reported by nearly all countries in the WHO European Region, by contrast, taxation of sugar-sweetened beverages lags behind with fewer than 45% of countries in the region taxing sugar-sweetened beverages [6]. Early intervention in childhood is critical to establishing lifelong healthy habits and preventing noncommunicable diseases. Implementing strong marketing restrictions on unhealthy foods and mandatory reformulation and front of pack labelling systems to reduce sugar, salt, and fat content can help protect children from diet-related health risks and create healthier food environments from an early age. Despite effectiveness, these policies face many challenges including crowded political agendas, disinformation, and industry interference.

The WHO Regional Office for Europe has identified tacking NCDs as a core priority of the Second European Programme of Work (EPW2). To inform this work WHO/Europe collected and synthesized over 1200 inputs on priority actions from policymakers, health and care providers, people with lived experience, youth, civil society and WHO experts. Key priorities that emerged include: strengthening political commitment; fostering multisectoral collaboration and meaningful engagement; countering commercial determinants of health; leveraging data for impact; advancing implementation of the best buys; addressing climate change; enhancing health literacy and self-managment; and strengthening international cooperation. Responding effectively to these priorities requires a whole of government and whole of society approach. It requires raising NCDs and mental health on local and global political agendas, implementing and enforcing proven policies, and advancing a fundamental shift toward multisectoral approaches.

Addressing these challenges and responding to the complex needs of individuals and systems in the face of the rising megatrends—health security, climate change, ageing populations, rising burden of NCDs and mental health disorders, and technological advances–requires better integration of our systems for prevention and management of physical and mental health and transforming our environments– natural, built, and digital–putting people at the centre of the process. Leveraging this expertise, passion, and real-world experience, particularly from those living with NCDs, is key to reshaping health systems, care delivery, and environments. This approach underpins WHO/Europe’s dual-track effort to accelerate collective action to deliver public health gains by 2030 (RACE to the Finish) and ultimately shape healthier environments and communities (Vision 2050).

  1. Author Declaration

  2. Author contributions: All authors have accepted responsibility for the entire content of this submitted manuscript and approved submission. The authors are staff members of the World Health Organization. The authors affiliated with the World Health Organization (WHO) are alone responsible for the views expressed in this publication and they do not necessarily represent the decisions or policies of the World Health Organization. Funding: Authors state no funding involved. Conflict of interest: Authors state no conflict of interest. Ethical statement: Primary data for human nor for animals were not collected for this research work.

  3. Autorenerklärung

  4. Beiträge der Autoren: Alle Autoren haben die Verantwortung für den gesamten Inhalt dieses eingereichten Manuskripts übernommen und die Einreichung genehmigt. Die Autoren sind Mitarbeiter der Weltgesundheitsorganisation. Die Autoren, die mit der Weltgesundheitsorganisation (WHO) verbunden sind, sind allein verantwortlich für die in dieser Veröffentlichung geäußerten Ansichten, die nicht notwendigerweise die Entscheidungen oder Richtlinien der Weltgesundheitsorganisation widerspiegeln. Finanzierung: Die Autoren geben an, dass keine Finanzierung beteiligt ist. Interessenkonflikt: Die Autoren geben an, dass es keinen Interessenkonflikt gibt. Ethik-Erklärung: Primärdaten für Menschen oder Tiere wurden nicht für diese Forschungsarbeit gesammelt.

References

1. Frieden TR, Cobb LK, Leidig RC, Mehta S, Kass D. Reducing premature mortality from cardiovascular and other non-communicable diseases by one third: achieving sustainable development goal indicator 3.4. 1. Global Heart 2020;15:50.10.5334/gh.531Search in Google Scholar PubMed PubMed Central

2. World Health Organization. Regional Office for Europe. Avoidable mortality, risk factors and policies for tackling noncommunicable diseases – leveraging data for impact: monitoring commitments in the WHO European Region ahead of the Fourth United Nations High-Level Meeting. Copenhagen: WHO Regional Office for Europe; 2025. Licence: CC BY-NC-SA 3.0 IGO.Search in Google Scholar

3. World Health Organization. WHO global report on trends in prevalence of tobacco use 2000–2030. Geneva: World Health Organization, 2024. https://www.who.int/publications/i/item/9789240088283. Accessed: 14 May 2025Search in Google Scholar

4. World Health Organization. Regional Office for Europe. Action on salt and hypertension: reducing cardiovascular disease burden in the WHO European Region. World Health Organization. Regional Office for Europe, 2024. https://iris.who.int/handle/10665/376580. Accessed: 10 May 2025Search in Google Scholar

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Published Online: 2025-09-05
Published in Print: 2025-09-25

World Health Organization [2025]. Licensee: De Gruyter Brill

This is an open access article distributed under the terms of the Creative Commons Attribution IGO License (http://creativecommons.org/licenses/by/3.0/igo/legalcode), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organisation or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article’s original URL.

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