Home Crystal structure of bis(4-phenylpiperazin-1-ium) bis(2-(4-phenylpiperazin-1-yl)succinato-κ2O,O′)copper(II) tetrahydrate, C48H70CuN8O12, [C10H14N2]2[Cu(C14H17N2O4)2] ⋅ 4 H2O
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Crystal structure of bis(4-phenylpiperazin-1-ium) bis(2-(4-phenylpiperazin-1-yl)succinato-κ2O,O′)copper(II) tetrahydrate, C48H70CuN8O12, [C10H14N2]2[Cu(C14H17N2O4)2] ⋅ 4 H2O

  • Jiehye Shin , Jaeun Kang , Kang Min Ok and Junghwan Do ORCID logo EMAIL logo
Published/Copyright: January 21, 2020
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Zeitschrift für Kristallographie - New Crystal Structures
From the journal Zeitschrift für Kristallographie - New Crystal Structures Volume 235 Issue 3

Abstract

C48H70CuN8O12, triclinic, P1̄ (no. 2), a = 9.4869(1) Å, b = 11.2213(1) Å, c = 12.0819(1) Å, α = 74.608(1)°, β = 78.441(1)°, γ = 86.820(1)°, V = 1214.90(2) Å3, Z = 1, Rgt(F) = 0.0460, wRref(F2) = 0.1239, T = 296(2) K.

CCDC no.: 1974546

The molecular structure is shown in the figure (Carbon-bound hydrogen atoms are removed for clarity.). Table 1 contains crystallographic data and Table 2 contains the list of the atoms including atomic coordinates and displacement parameters.

Table 1:

Data collection and handling.

Crystal:Green polyhedron
Size:0.57 × 0.38 × 0.35 mm
Wavelength:Mo Kα radiation (0.71073 Å)
μ:0.52 mm−1
Diffractometer, scan mode:Bruker P4, ω
θmax, completeness:33.1°, >99%
N(hkl)measured, N(hkl)unique, Rint:19878, 7895, 0.027
Criterion for Iobs, N(hkl)gt:Iobs > 2 σ(Iobs), 5851
N(param)refined:329
Programs:Bruker [1], SHELX [2], [3], Diamond [4]
Table 2:

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å2).

AtomxyzUiso*/Ueq
Cu10.5000000.0000001.0000000.02852(9)
O10.60683(14)0.07860(11)1.08400(10)0.0368(3)
O20.67703(15)0.26125(12)1.08993(12)0.0415(3)
O30.29525(15)0.12342(12)1.05074(13)0.0480(3)
O40.16977(15)0.29763(13)1.02906(14)0.0508(4)
C10.62013(17)0.19420(15)1.04447(14)0.0314(3)
C20.56250(18)0.25435(14)0.93191(14)0.0315(3)
H20.6312300.3181640.8829200.038*
C30.41848(19)0.31806(15)0.96113(16)0.0365(4)
H3A0.3990480.3731540.8890300.044*
H3B0.4298950.3692341.0120430.044*
C40.28521(19)0.23769(16)1.01912(15)0.0361(4)
N10.55865(14)0.15839(12)0.86617(11)0.0281(3)
N20.66399(15)0.26522(13)0.61478(12)0.0322(3)
C50.70816(18)0.14099(16)0.80379(14)0.0331(3)
H5A0.7116000.0646930.7799690.040*
H5B0.7729770.1318580.8582480.040*
C60.76259(19)0.24560(17)0.69645(15)0.0364(4)
H6A0.7701460.3208340.7199650.044*
H6B0.8574960.2251550.6585080.044*
C70.46615(18)0.18571(17)0.77738(15)0.0356(4)
H7A0.3700360.2052110.8137750.043*
H7B0.4596010.1121380.7509610.043*
C80.51955(19)0.29179(17)0.67196(15)0.0387(4)
H8A0.4547440.3041210.6171410.046*
H8B0.5208900.3671770.6966110.046*
C90.71200(19)0.34301(15)0.50067(14)0.0323(3)
C100.6303(2)0.34785(17)0.41577(15)0.0391(4)
H100.5440620.3046770.4358920.047*
C110.6766(2)0.41664(18)0.30132(16)0.0456(4)
H110.6218580.4179290.2452020.055*
C120.8025(2)0.48283(19)0.27006(17)0.0505(5)
H120.8323630.5297960.1935850.061*
C130.8837(2)0.4787(2)0.35344(18)0.0523(5)
H130.9690140.5231820.3329200.063*
C140.8398(2)0.40853(18)0.46829(16)0.0432(4)
H140.8964750.4057360.5234240.052*
N30.06144(17)−0.16510(15)0.82835(14)0.0421(4)
H3C−0.005416−0.2061320.8866910.050*
H3D0.146541−0.1989790.8384510.050*
N40.12882(17)0.02941(14)0.61656(13)0.0381(3)
C150.0615(2)−0.0340(2)0.83097(18)0.0470(4)
H15A0.090381−0.0284860.9020480.056*
H15B−0.035049−0.0004680.8314650.056*
C160.1627(2)0.04076(18)0.72656(17)0.0425(4)
H16A0.1565930.1269600.7278880.051*
H16B0.2605460.0128960.7308390.051*
C170.0319(3)−0.17569(19)0.71499(19)0.0528(5)
H17A−0.065496−0.1480240.7083220.063*
H17B0.039661−0.2615430.7125320.063*
C180.1361(3)−0.09928(19)0.61428(19)0.0516(5)
H18A0.232987−0.1302380.6183140.062*
H18B0.114102−0.1063580.5412730.062*
C190.2047(2)0.11313(18)0.51468(16)0.0402(4)
C200.2934(3)0.0740(2)0.42412(19)0.0554(5)
H200.310649−0.0098580.4316750.067*
C210.3559(3)0.1598(3)0.3228(2)0.0663(7)
H210.4150580.1324560.2630960.080*
C220.3321(3)0.2835(3)0.3090(2)0.0660(7)
H220.3721100.3401060.2397580.079*
C230.2484(3)0.3229(2)0.3988(3)0.0677(7)
H230.2335340.4070770.3910090.081*
C240.1856(2)0.2393(2)0.5009(2)0.0561(5)
H240.1298440.2679640.5611320.067*
WO10.9865(2)0.2556(2)0.87464(19)0.0715(5)
H250.945(4)0.336(4)0.876(3)0.111(13)*
H261.059(4)0.255(3)0.907(3)0.087(11)*
WO20.8163(3)0.4660(2)0.9187(2)0.0881(7)
H270.835(4)0.531(3)0.935(3)0.096(11)*
H280.789(5)0.428(4)0.983(4)0.140(19)*

Source of material

The mixture of CuCl2 (0.040 g, 0.3 mmol), 1-phenylpiperazine (0.136 mL, 0.9 mmol), maleic acid (0.035 g, 0.3 mmol) in water (1.0 mL) was sealed under vacuum in a Pyrex tube and heated to 70 °C for 68 h, then cooled to room temperature at 20 °C/h. The pH before and after the reaction were 7 and 6, respectively. The green polyhedral crystals were recovered by vacuum filtration and washed with distilled water. The product is stable in air.

Experimental details

All hydrogen atoms bound to carbon and nitrogen atoms were placed in calculated positions and refined as riding model except for the hydrogen atoms in water molecules, which were located in difference Fourier maps, and their positions and isotropic displacement parameters were refined.

Comment

Recently, we reported a series of “unnatural”, tailor-made α-amino acid metal complexes containing racemic mixtures of the chiral ligands, which are formed under mild hydrothermal conditions in situ by Michael addition of amine to fumaric acid or trans-muconic acid [5], [6], [7], [8]. For example, the hydrothermal reaction of a nickel salt, benzylamine, and fumaric acid in water can produce a nickel N-benzyl aspartate complex [6]. This type of Michael reaction, i.e., the direct amination of α,β-unsaturated dicarboxylic acid is rarely reported, although several synthetic methods for amination of α,β-unsaturated dicarboxylic acid derivatives, such as mono- or diester and monoamide, are well known [9]. In this study we report a new complex containing the racemic 2-(4-phenylpiperazin-1-yl)succinato ligand, which is formed in situ by Michael addition of 4-phenylpiperazine to maleic acid.

The crystal structure of the title complex contains discrete centrosymmetric mononuclear Cu(C14H17N2O4)22− anions. One crystallographically unique copper atom is coordinated by two racemic 2-(4-phenylpiperazin-1-yl)succinato ligands to form a Cu(rac-phenylpiperazinyl succinato)2 unit. One nitrogen and two oxygen atoms in each D- and L- piperazinyl succinate are bonded to the Cu to complete a distorted octahedral arrangement with distances in the range of 1.955(1) Å−2.396(1) Å. The other two oxygen atoms in each carboxylate group of the phenylpiperazinyl succinate keep uncoordinated. A bond valence sum (BVS) calculation gives a value of 1.81 for Cu(1) indicating an oxidation state of +2.00 [10]. The [Cu(C14H17N2O4)2]2− anion charge is balanced by two mono-protonated phenylpiperazinium cations (see the figure). Water molecules occupy the remaining lattice volume. The formula can be represented by [phenylpiperazium+]2[Cu2+(rac-phenylpiperazinyl succinate2−)2]⋅4 H2O.

The structure of Cu(rac-phenylpiperazinyl succinate)22− is very similar to Cu(rac-piperazinyl succinate)2 in ref. 7. The major difference arises from the charge of the ligands. Unlike the divalent phenylpiperazinyl succinate in the title complex, monovalent piperazinyl succinate anion is produced in Cu(rac-piperazinyl succinate)2 complex from addition of fumaric acid to diamine, piperazine forming a zwitterion, i.e., the positive charge is localized at the protonated terminal nitrogen atom of piperazine moiety and the negative charge in the vicinity of carboxylate, to form neutral Cu2+(rac-piperazinyl succinate−)2 complex [7].

The Cu(phenylpiperazinyl succinate)22− anion forms extended networks of N—H⋯O hydrogen bonds with the phenylpiperazinium cation with the distance of d(N⋯O) = 2.735(2) Å and 2.904(2) Å respectively. Furthermore, the lattice water molecules are hydrogen bonded to the not Cu-coordinated (O2, O4) oxygen atoms in phenylpiperazinyl succinate ligand [d(O⋯O) = 2.833(2) Å, 2.900 Å, and 2.930 Å] or to each other in a complicated arrangement, which results in the formation of layers in the ab-plane. Thus the hydrogen bonded layers stack along the c-axis and interact through van der Waals forces.

Funding source: National Research Foundation of Korea

Award Identifier / Grant number: 2017R1D1A1B03030659

Funding statement: This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (2017R1D1A1B03030659).

References

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Received: 2019-09-19
Accepted: 2019-12-28
Published Online: 2020-01-21
Published in Print: 2020-04-28

©2020 Jiehye Shin et al., published by De Gruyter, Berlin/Boston

This work is licensed under the Creative Commons Attribution 4.0 Public License.

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  60. Crystal structure of bis(2-hydroxy-6-((phenylimino)methyl)phenolato-κ2N,O)copper(II), C26H20CuN2O4
  61. The crystal structure of 2-p-fluorophenyl-5-dihydroxymethyl-1,3,4-oxadiazole, C9H7FN2O3
  62. Crystal structure of dichloridobis(4-chlorophenyl-κC1)(1,10-phenanthroline-κ2N,N′)tin(IV), C24H16Cl4N2Sn
  63. Crystal structure of bis{bromido-triphenyltin(IV)}(μ2-[4,4′-bipyridine]1,1′-dioxide-κ2O:O′), C46H38Br2N2O2Sn2
  64. Crystal structure of 2-(5-chloro-quinolin-8-yloxy)-N-quinolin-8-yl-acetamide, C20H14N3O2Cl
  65. Crystal structure of bis(N-(1-(3-ethylpyrazin-2-yl)ethylidene)-3-hydroxy-2-naphthohydrazonato-κ3N,N′,O)cobalt(II) — dimethylformamide (1/1), C41H41N9O5Co
  66. Crystal structure of bis[2-(1-(3-ethylpyrazin-2-yl)ethylidene)-1-tosylhydrazin-1-ido-κ3-N,N′,O]copper(II), C30H34N8O4S2Cu
  67. Crystal structure of (2-p-tolylpyrimidine-κ2C,N)(triphenylphosphane-κP) palladium(II), C29H24ClN2PPd
  68. Halogen bonding in crystal structure of bis(1,4,7,10-tetraoxacyclododecane-κ4O,O′,O′′,O′′′)cesium triiodide, C16H32CsI3O8
  69. The synthesis and crystal structure of N-(3-cyano-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylsulfinyl)-1H-pyrazol-5-yl)-2-phenylacetamide, C20H10N4Cl2F6O2S
  70. The crystal structure of 4-(trifluoromethyl)nicotinic acid, C7H4F3NO2
  71. Crystal structure of 3-(2-methylbenzyl)thiazolidin-2-one, C11H13ONS
  72. The crystal structure of 2,2,2-trifluoro-1-(isoquinolin-1-yl)ethane-1,1-diol, C11H8F3NO2
  73. The crystal structure of 3-bromoisonicotinic acid, C6H4BrNO2
  74. The crystal structure of 5-nitropicolinic acid monohydrate, C6H6N2O5
  75. The crystal structure of 3-(4-hydroxybenzyl)-1,5-dioxaspiro[5.5]undecane-2,4-dione, C16H18O5
  76. Crystal structure of [[Mo3Se7(S2CNEt2)3]2(μ-Se)] ⋅ 2(C6H4Cl2), C42H68Cl4Mo6N6S12Se15
  77. Crystal structure of (E)-4-hydroxy-3-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)pent-3-en-2-one, C13H12N2O3S
  78. The crystal structure of (2,3-dioxo-5,6:13,14-dibenzo-9,10-benzo-1,4,8,11-7, 11-diene-κ4N,N′,N′′,N′′′)-nickel(II), Ni(C22H14N4O2)
  79. Crystal structure of 3-(1-benzyl-2-ethyl-4-nitro-1H-imidazol-5-ylthio)-propanoic acid, C15H17N3O4S
  80. The crystal structure of dichlorobis(2-(dicyclohexylphosphino)-2′,4′,6′-tri-i-propyl-1,1′-biphenyl) palladium(II)-dichloroform, C68H100Cl8P2Pd
  81. Crystal structure and antimicrobial properties of (1,4,7,10-tetraoxacyclododecane-κ4O,O′,O′′,O′′′)cesium(I) pentaiodide, C16H32CsI5O8
https://doi.org/10.1515/ncrs-2019-0706
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Articles in the same Issue

  1. Frontmatter
  2. Crystal structure of catena-poly[(μ2-3-(benzo[d]thiazol-2-yl)-5-carboxybenzoato-κ2N:O)silver(I)], C15H8AgNO4S
  3. Crystal structure of bis(4-phenylpiperazin-1-ium) bis(2-(4-phenylpiperazin-1-yl)succinato-κ2O,O′)copper(II) tetrahydrate, C48H70CuN8O12, [C10H14N2]2[Cu(C14H17N2O4)2] ⋅ 4 H2O
  4. Crystal structure of triaqua-bis(2-(6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydronaphthalen-1-yl)-1-(2-oxo-2,5-dihydrofuran-3-yl)ethane-1-sulfonato-κ2O,O′)calcium(II) – ethanol (1/2), C44H76CaO19S2
  5. The crystal structure of ethyl 5-(4-(diphenylamino)phenyl)thiophene-2-carboxylate, C25H21NO2S
  6. The crystal structure of 5-bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine, C7H6BrN5
  7. The crystal structure of (E)-5-chloro-2-hydroxy-N′-(2-hydroxy-4-methoxybenzylidene)benzohydrazide, C15H13ClN2O4
  8. The crystal structure of (2Z,2′Z)-N′,N′′′′-(pyridine-2,6-dicarbonyl)dipicolinohydrazonamide, C19H17N9O2
  9. Photochromic properties and crystal structure of 3,3′-(perfluorocyclopent-1-ene-1,2-diyl)bis(5-(4-(azidomethyl)phenyl)-2-methylthiophene), C29H20F6N6S2
  10. Crystal structure of aqua-dichlorido-(4-(((3-ethoxy-2-oxidobenzylidene)hydrazono)(oxido)methyl)pyridin-1-ium-κ3N,O,O′)iron(III), C15H16Cl2N3O4Fe
  11. Crystal structure of catena-poly[diaqua-(μ2-4,4′-bipyridine-κ2N:N′)-bis(2,3,4,5-tetrabromo-6-carboxybenzoato-κ1O)-nickel(II)], C26H14Br8NiN2O10
  12. Crystal structure of diethanol-κ1O-bis(μ2-N-((2-oxidonaphthalen-1-yl)methylene)pyrazine-2-carbohydrazonato-κ5N,O,O′:O′:N′)-bis(nitrato-κ2O,O′)dieuropium(III), C36H32N10O12Eu2
  13. The crystal structure of 2-aminoisophthalic acid, C8H7NO4
  14. Crystal structure of (E)-2-(4-((3,4-difluorobenzyl)oxy)styryl)-4,6-dimethoxybenzaldehyde, C24H20F2O4
  15. Crystal structure of 2-benzoylpyrene, C23H14O
  16. Crystal structure of chlorido-(η6-p-cymene)-(N-(2-fluorophenyl)-1-(pyridin-2-yl)methanimine-κ2N,N′)ruthenium(II) – acetone (1/1), C22H23ClN2F7OPRu
  17. The crystal structure of 2-bromoisonicotinic acid, C6H4BrNO2
  18. Crystal structure of 1,3,5,7-tetraphenyl-8-(N-phenylformamido)-2-oxa-5-azabicyclo[4.2.0]oct -3-en-7-yl benzoate, C44H34N2O4
  19. Synthesis and crystal structure of 4-(3-acetyl-5-(thiophen-2-yl)-2,3-dihydro-1,3,4-oxadiazol-2-yl)-7-(diethylamino)-2H-chromen-2-one, C21H21N3O4S
  20. Crystal structure of poly[diaqua-(μ2-4,4′-bipyridine-κ2N:N′)-(μ2-3,4,5,6-tetrafluorophthalato-κ2O:O′)nickel(II)], C18H12F4NiN2O6
  21. Crystal structure of 4-hydroxynaphtho[2,3-b]benzofuran-6,11-dione, C16H8O4
  22. The crystal structure of 3,10-bis(4-methoxyphenyl)-6,12-dibenzyl-2,9-acetyl-6,12-diazapentacyclo[6.3.1.02,7.04,11.05,9]dodecane – acetone (1/1), C45H48N2O5
  23. The crystal structure of (E)-2-(((2-(1H-indol-3-yl)ethyl)iminio)methyl)-6-bromophenolate, C17H15N2BrO
  24. Crystal structure of catena-poly[diaqua-(μ2-oxalyl dihydrazide-κ4N,O:N′,O′)-bis(μ2-pyridine-2,3-dicarboxylato-κ3N,O,O′)dicadmium(II)] hexahydrate, C16H28O18N6Cd2
  25. Crystal structure of poly[tetra-(μ4-naphthalene-1,8-dicarboxylato-κ4O:O,O′: O′′:O′′,O′′′)-(μ4-oxo-κ4O:O:O:O) penta-lead(II)], C48H24O17Pb5
  26. Crystal structure of 5H-dibenzo[c,f][1,5]oxabismocin-12 (7H)-yl acetate, C16H15O3Bi
  27. The crystal structure of 2-(4-chloro-6-nitrophenyl)-1-(4-chloro-3-nitrophenyl)diazene 1-oxide, C12H6Cl2N4O5
  28. Crystal structure of bis(3-methyl-N-(1-(pyrazin-2-yl)ethylidene)benzohydrazonato-κ3O,N,N′)nickel(II), C28H26N8O2Ni
  29. Crystal structure of 3,10-bis(4-chlorophenyl)-6,12-dibenzyl-2,9-acetyl-6,12-diazapentacyclo[6.3.1.02,7.04,11.05,9]-dodecane, C40H36Cl2N2O2
  30. Crystal structure of bis[(μ2-4⋯O,O′:O′)-(4-hydroxybenzoato-κ2O,O′)-(1,10-phenanthroline-κ2N,N′)]-di-lead(II)μ-4-hydroxybenzoato-κ3O,O′:O′;κ3O,O′:O′-bis-[(4-hydroxybenzoato-κ2O,O′)bis(1,10-phenanthroline-κ2N,N′)di-lead(II)] monohydrate, C52H36N4O12Pb2 ⋅ H2O
  31. Crystal structure of poly[diaqua-(μ3-3,4,5,6-tetrafluoro-phthalato-κ3O:O′:O′′)-(μ2-1,2-bis(4-pyridyl)ethene-κ2N:N′)cobalt(II)], C14H9CoF4NO6
  32. Crystal structure of 7-hydroxy-4-phenyl-2H-chromen-2-one, C15H10O3
  33. Crystal structure of 3,7-dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione 4-hydroxybenzoic acid, C20H24N4O6
  34. Crystal structure of catena-poly[(μ2-1,5-dimethyl-2-phenyl-4-((pyridin-4-ylmethylene)amino)-1,2-dihydro-3H-pyrazol-3-one-κ2N:O)-bis(nitrato-κ1O)zinc(II)], C17H16N6O7Zn
  35. The crystal structure of diaqua-bis(6-aminopicolinato-κ2N,O)magnesium(II), C12H14O6N4Mg
  36. Crystal structure of (pyridine-2-carboxamide-κ2N,O)-[tris((1H-benzo[d]imidazol-2-yl)methyl)amine-κ4N,N′,N′′,N′′′]nickel(II) diperchlorate — methanol (1/3), C33H39Cl2N9NiO12
  37. Crystal structure of catena-poly[diaqua-bis(3-(4-trifluoromethyl-phenyl)-acrylato-κO1)-(μ2-1,4-bis(1-imidazolyl)benzene-κ2N3:N3′)cobalt(II)], C32H26CoF6N4O6
  38. Crystal structure of (E)-3-(2-(2-hydroxy-4-methoxystyryl)-3,3-dimethyl-3H-indol-1-ium-1-yl)propane-1-sulfonate monohydrate, C22H25NO5S⋅H2O
  39. The crystal structure of bis(N-oxy-2-(1H-tetrazol-1-yl) acetamide κ2O,O′)-diaqua-zinc(II), C6H12ZnN10O6
  40. Crystal structure of (E)-4-((4-chlorophenylimino)methyl)pyridinium 3,5-dinitrobenzoate, C19H13ClN4O6
  41. Crystal structure of dichlorido-bis((E)-2-((pyridin-4-ylmethylene)amino)phenol)zinc(II), C24H20Cl2N4O2Zn
  42. Crystal structure of cyclo-[tetrachlorido-bis(μ2-p-xylylenediamine-κ2N:N′)dipalladium(II)] dimethyl sulfoxide solvate, C20H36Cl4N4O2Pd2S2
  43. Crystal structure of 4-(3-fluorophenyl)-7-hydroxy-2H-chromen-2-one, C15H9FO3
  44. Crystal structure of (E)-2-((2-(pyrimidin-2-yl)hydrazono)methyl)quinolin-1-ium perchlorate – methanol (1/1), C15H16N5O5Cl
  45. The crystal structure of bis(N-(amino(pyridin-2-yl)methylene)-5-chloro-2-hydroxybenzohydrazonato-κ3N,N′,O)zinc(II) – methanol (2/5), C57H60Cl2N16O13Zn2
  46. Synthesis and crystal structure of 4,4′-di(4-pyridyl)-6,6′-di(tert-butyl)-2,2′-[propylenedioxybis(nitrilomethylidyne)]diphenol, C35H40N4O4
  47. Crystal structure of (3E,3′E)-3,3′-((1,3,4-thiadiazole-2,5-diyl)bis(sulfanediyl))bis(4-hydroxy-4-phenylbut-3-en-2-one), C22H18N2O4S3
  48. Crystal structure of (N-benzyl-N-methyl-dithiocarbamato-κ2S,S′)di(4-chlorobenzyl)chloridotin(IV), C23H22Cl3NS2Sn
  49. Crystal structure of (1,4,7,10,13,16-hexaoxacyclooctadecane-κ6O6) sodium bromide hydrate, [Na(18-crown-6)]Br ⋅ H2O, C12H26BrNaO7
  50. Crystal structure of 7-ethoxyl-6,8-difluoro-4-oxo-1-phenyl-1,4-dihydro-quinoline-3-carboxylic acid, C18H13F2N1O4
  51. Crystal structure of chlorido (2-(4-ethylphenyl)pyrimidine-k2C,N)(triphenylphosphane-kP) palladium(II), C30H26ClN2PPd
  52. Crystal structure of 18-crown-6 – 1,4-diiodotetrafluorobenzene – acetonitrile (1/1/2), C22H30F4I2N2O6
  53. Crystal structure of diisobutyl 2,5-dihydroxycyclohexa-1,4-diene-1,4-dicarboxylate, C16H24O6
  54. Crystal structure of poly[[tris(μ2-cis-1,2-cyclohexanedicarboxylato)-κ2O, O′]-bis[μ3-1,3,5-tris[(1H-imidazol-1-yl)methyl]benzene-κ3N, N′,N′′]-trizinc(II)] – water (1/20), C60H106N12O32Zn3
  55. The synthesis and crystal structure of 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carboxamide–tetrahydrofuran (1/1), C16H14N4Cl2F6O3S
  56. Crystal structure of dimethylbis(diisopropyldithiocarbamato-κ2S,S′)tin(IV), C16H34N2S4Sn
  57. Crystal structure of diisopropyl 2,5-dihydroxycyclohexa-1,4-diene-1,4-dicarboxylate, C14H20O6
  58. The synthesis and crystal structure of ethyl (E)-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-5-((2-methoxybenzylidene)amino)-4-((trifluoromethyl)sulfinyl)-1H-pyrazole-3-carboxylate, C22H15N3Cl2F6O4S
  59. The crystal structure of a matrine derivative, 13-(methylamine-1-yl) carbodithioate matrine, C17H27N3OS2
  60. Crystal structure of bis(2-hydroxy-6-((phenylimino)methyl)phenolato-κ2N,O)copper(II), C26H20CuN2O4
  61. The crystal structure of 2-p-fluorophenyl-5-dihydroxymethyl-1,3,4-oxadiazole, C9H7FN2O3
  62. Crystal structure of dichloridobis(4-chlorophenyl-κC1)(1,10-phenanthroline-κ2N,N′)tin(IV), C24H16Cl4N2Sn
  63. Crystal structure of bis{bromido-triphenyltin(IV)}(μ2-[4,4′-bipyridine]1,1′-dioxide-κ2O:O′), C46H38Br2N2O2Sn2
  64. Crystal structure of 2-(5-chloro-quinolin-8-yloxy)-N-quinolin-8-yl-acetamide, C20H14N3O2Cl
  65. Crystal structure of bis(N-(1-(3-ethylpyrazin-2-yl)ethylidene)-3-hydroxy-2-naphthohydrazonato-κ3N,N′,O)cobalt(II) — dimethylformamide (1/1), C41H41N9O5Co
  66. Crystal structure of bis[2-(1-(3-ethylpyrazin-2-yl)ethylidene)-1-tosylhydrazin-1-ido-κ3-N,N′,O]copper(II), C30H34N8O4S2Cu
  67. Crystal structure of (2-p-tolylpyrimidine-κ2C,N)(triphenylphosphane-κP) palladium(II), C29H24ClN2PPd
  68. Halogen bonding in crystal structure of bis(1,4,7,10-tetraoxacyclododecane-κ4O,O′,O′′,O′′′)cesium triiodide, C16H32CsI3O8
  69. The synthesis and crystal structure of N-(3-cyano-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(trifluoromethylsulfinyl)-1H-pyrazol-5-yl)-2-phenylacetamide, C20H10N4Cl2F6O2S
  70. The crystal structure of 4-(trifluoromethyl)nicotinic acid, C7H4F3NO2
  71. Crystal structure of 3-(2-methylbenzyl)thiazolidin-2-one, C11H13ONS
  72. The crystal structure of 2,2,2-trifluoro-1-(isoquinolin-1-yl)ethane-1,1-diol, C11H8F3NO2
  73. The crystal structure of 3-bromoisonicotinic acid, C6H4BrNO2
  74. The crystal structure of 5-nitropicolinic acid monohydrate, C6H6N2O5
  75. The crystal structure of 3-(4-hydroxybenzyl)-1,5-dioxaspiro[5.5]undecane-2,4-dione, C16H18O5
  76. Crystal structure of [[Mo3Se7(S2CNEt2)3]2(μ-Se)] ⋅ 2(C6H4Cl2), C42H68Cl4Mo6N6S12Se15
  77. Crystal structure of (E)-4-hydroxy-3-((5-phenyl-1,3,4-oxadiazol-2-yl)thio)pent-3-en-2-one, C13H12N2O3S
  78. The crystal structure of (2,3-dioxo-5,6:13,14-dibenzo-9,10-benzo-1,4,8,11-7, 11-diene-κ4N,N′,N′′,N′′′)-nickel(II), Ni(C22H14N4O2)
  79. Crystal structure of 3-(1-benzyl-2-ethyl-4-nitro-1H-imidazol-5-ylthio)-propanoic acid, C15H17N3O4S
  80. The crystal structure of dichlorobis(2-(dicyclohexylphosphino)-2′,4′,6′-tri-i-propyl-1,1′-biphenyl) palladium(II)-dichloroform, C68H100Cl8P2Pd
  81. Crystal structure and antimicrobial properties of (1,4,7,10-tetraoxacyclododecane-κ4O,O′,O′′,O′′′)cesium(I) pentaiodide, C16H32CsI5O8
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