Vertical transmission of Trypanosoma evansi in dromedary camels and studies on fetal pathology, diagnosis and treatment

Shirish D. Narnaware; Samar K. Ghorui; Sanjay Kumar; Nitin V. Patil

doi:10.1515/ap-2016-0043

Article

Vertical transmission of Trypanosoma evansi in dromedary camels and studies on fetal pathology, diagnosis and treatment

Shirish D. Narnaware , Samar K. Ghorui , Sanjay Kumar and Nitin V. Patil

Published/Copyright: March 30, 2016

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From the journal Acta Parasitologica Volume 61 Issue 2

Abstract

In the present study, a total of 14 (73.68%) cases of abortions and two (100%) cases of still births were detected positive for Trypanosoma evansi infection by wet and dry blood smear examination and fetal tissue PCR in camels of an organized farm. The abortions in infected dams were recorded from 8 to 11.5 month of gestation, however majority occurred during 9^th to 10^th month. The important laboratorial findings in infected dams were anemia, hypoglycemia, hyperproteinemia and leukocytosis. At necropsy the T. evansi infected aborted and still born fetuses showed subcutaneous edema, presence of moderate amount of dark red hemolysed blood in thoracic and abdominal cavity, bronchopneumonia, hepatic necrosis and acute congestion in all vital organs. Microscopically, there was severe congestion, thickening of bronchial and alveolar wall and mononuclear infiltration in the fetal lung, necrotic and degenerative changes in the liver, nephritis along with severe congestion and tubular necrosis in the kidneys and necrotic and degenerative changes and congestion of capillaries in the brain. The T. evansi DNA was detected by PCR from blood, lung, spleen, liver, kidney and brain of all the infected aborted and still born fetuses. The results of the study indicated that T. evansi can cross placental barrier and cause pathological events in the fetus resulting into abortion or still birth in pregnant camels.

Key words: Abortion; camel; pathology; transplacental transmission; Trypanosoma evansi

Acknowledgement

The authors are thankful to Dr. B.L. Chirania and Dr. Kashi Nath, Veterinary Officers at National Research Centre on Camel, Bikaner (India) for help in sample collection.

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Received: 2015-5-14

Revised: 2015-10-31

Accepted: 2015-12-7

Published Online: 2016-3-30

Published in Print: 2016-6-1

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Articles in the same Issue

https://doi.org/10.1515/ap-2016-0043

Keywords for this article

Abortion; camel; pathology; transplacental transmission; Trypanosoma evansi