Neera, a non-fermented traditional drink from coconut spadix restores the redox status in sodium fluoride intoxicated mice
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Prabha Silpa
Abstract
Objectives
Neera, non-fermented coconut inflorescence sap (NFCIS) and its fermented form, toddy (FCIS) are the two well-known traditional drinks in South India. Both the saps show high rejuvenation effect and NFCIS is used for the curing of bronchial suffocation, anemia, tuberculosis and piles in traditional medicine. But, a few scientific studies have been reported on their health benefits so far. Presently, the antioxidant effect of both non-fermented (NFCIS) and fermented form (FCIS) of coconut inflorescence were analyzed in experimental animals.
Methods
The free radical scavenging property of FCIS and NFCIS was analyzed in vitro. The effect of these saps on mitigating sodium fluoride (NaF) deteriorated redox status was evaluated in mice.
Results
NFCIS exhibited high antioxidant activity than its fermented form. NFCIS reduces metal ions and scavenge hydroxyl and DPPH radicals with IC50 values 6.5 ± 1.9 and 44 ± 3.14 µL/mL, respectively. Supplementation of NFCIS for 14 days increased SOD, CAT and GPx activities and GSH level in liver by 51.67, 52, 27.88 and 35.77%, respectively against NaF induced decline with a concomitant decrease in lipid peroxidation to 40.76%. Saps rich in minerals indicate pharmaceutical and nutritional value.
Conclusion
The study revealed the antioxidant efficacy of non-alcoholic natural drink, Neera and recommends an alternative for synthetic carbonated soft drinks. The regular consumption of Neera may protect the body from various chronic diseases especially where the oxidative stress played as a key role.
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Research funding: None declared.
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Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
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Competing interests: No funding organizations played a role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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Ethical statement: Animal experiments were carried out with the prior consent from Institutional Animal Ethics Committee (IAEC/ACRC/16-12/17 dated 19/12/2016) and were strictly following the guidelines of Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA).
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Articles in the same Issue
- Frontmatter
- Reviews
- ‘Ilāj bi’l-Tadbīr (regimenal therapy): a core mode of Unani treatment
- Understanding hormones in terms of humours (Akhlat) in Unani system of medicine
- Review Articles
- Understanding Humma-e-Wabai (epidemic fever) and Amraz-e-Wabai (epidemic disease) in the light of Unani medicine
- Emergence of antimicrobial resistance and magnitude of Unani medicine – scope and challenges
- Medicinal importance of Papra (Podophyllum hexandrum Royle) in Unani System of Medicine
- Research Articles
- Comparative effects of berberine and piperine on the neuroprotective potential of neostigmine
- Neera, a non-fermented traditional drink from coconut spadix restores the redox status in sodium fluoride intoxicated mice
- Evaluation of wound healing potential of Bhallatakadi Ghrita – cow ghee based polyherbal formulation: in-vivo excision and incision wound model
- Effects of co-administration of Unani pharmacopoeia formulations Qurs Tabasheer Sartani and Arq Hara Bhara with CAT-I antitubercular drugs in rats
- Neurotoxicity of organic solvents with emphasis on the role of iron
- Regular consumption of “Nkui”, a Cameroonian traditional dish, may protect against cardiovascular and bone disorders in an estrogen deficiency condition
- A spatial-temporal study of complementary and alternative medicine (CAM) by type: exploring localization economies implications in urban areas in Ontario
- Complementary and alternative interventions for stroke recovery – a narrative overview of the published evidence
- The feasibility and acceptability of hypnotherapy among overweight and obese individuals in a Malaysia’s public university
- Effectiveness of wet cupping therapy on relieving pain in patients with chronic migraine: an observational study
- Effect of aromatherapy massage by orange essential oil on post-cesarean anxiety: a randomized clinical trial
- Effect of Sudarshan Kriya Yoga (SKY) on daytime and situational sleep propensity in novice practitioners: a prospective cohort study
- Comparison of instability resistance training, traditional resistance training and plyometric training on athletic performance parameters
- Individualized homeopathic medicines and Urtica urens mother tincture in treatment of hyperuricemia: an open, randomized, pragmatic, pilot trial
- Association of microsomal epoxide hydrolase gene (fast genotype) with lung functions impairment in wood workers
- Dietary glycine improves urine storage symptoms in urology outpatients
- Hypoxia-induced oxidative stress in high altitude population: impact of coenzyme Q10 supplementation
- Short Communications
- Terminalia arjuna induced testicular assault through Leydig cell derangement: an in vitro approach
- Effect of acupuncture on cognitive task performance of college students: a pilot study
- Yoga for children in the new normal – experience sharing
- Effect of Arogya Raksha Panchatantra (five lifestyle principles) on hematological parameters and anthropometric measures among healthy volunteers: a pilot study
- Case Reports
- Yellow phosphorous ingestion cause liver dysfunction and internal bleeding: a case study
- Effect of yoga on plasma glucose, lipid profile, blood pressure and insulin requirement in a patient with type 1 diabetes mellitus
- Management of Vipadika with Mahisha Gritha Padanimajjana – a case report
Articles in the same Issue
- Frontmatter
- Reviews
- ‘Ilāj bi’l-Tadbīr (regimenal therapy): a core mode of Unani treatment
- Understanding hormones in terms of humours (Akhlat) in Unani system of medicine
- Review Articles
- Understanding Humma-e-Wabai (epidemic fever) and Amraz-e-Wabai (epidemic disease) in the light of Unani medicine
- Emergence of antimicrobial resistance and magnitude of Unani medicine – scope and challenges
- Medicinal importance of Papra (Podophyllum hexandrum Royle) in Unani System of Medicine
- Research Articles
- Comparative effects of berberine and piperine on the neuroprotective potential of neostigmine
- Neera, a non-fermented traditional drink from coconut spadix restores the redox status in sodium fluoride intoxicated mice
- Evaluation of wound healing potential of Bhallatakadi Ghrita – cow ghee based polyherbal formulation: in-vivo excision and incision wound model
- Effects of co-administration of Unani pharmacopoeia formulations Qurs Tabasheer Sartani and Arq Hara Bhara with CAT-I antitubercular drugs in rats
- Neurotoxicity of organic solvents with emphasis on the role of iron
- Regular consumption of “Nkui”, a Cameroonian traditional dish, may protect against cardiovascular and bone disorders in an estrogen deficiency condition
- A spatial-temporal study of complementary and alternative medicine (CAM) by type: exploring localization economies implications in urban areas in Ontario
- Complementary and alternative interventions for stroke recovery – a narrative overview of the published evidence
- The feasibility and acceptability of hypnotherapy among overweight and obese individuals in a Malaysia’s public university
- Effectiveness of wet cupping therapy on relieving pain in patients with chronic migraine: an observational study
- Effect of aromatherapy massage by orange essential oil on post-cesarean anxiety: a randomized clinical trial
- Effect of Sudarshan Kriya Yoga (SKY) on daytime and situational sleep propensity in novice practitioners: a prospective cohort study
- Comparison of instability resistance training, traditional resistance training and plyometric training on athletic performance parameters
- Individualized homeopathic medicines and Urtica urens mother tincture in treatment of hyperuricemia: an open, randomized, pragmatic, pilot trial
- Association of microsomal epoxide hydrolase gene (fast genotype) with lung functions impairment in wood workers
- Dietary glycine improves urine storage symptoms in urology outpatients
- Hypoxia-induced oxidative stress in high altitude population: impact of coenzyme Q10 supplementation
- Short Communications
- Terminalia arjuna induced testicular assault through Leydig cell derangement: an in vitro approach
- Effect of acupuncture on cognitive task performance of college students: a pilot study
- Yoga for children in the new normal – experience sharing
- Effect of Arogya Raksha Panchatantra (five lifestyle principles) on hematological parameters and anthropometric measures among healthy volunteers: a pilot study
- Case Reports
- Yellow phosphorous ingestion cause liver dysfunction and internal bleeding: a case study
- Effect of yoga on plasma glucose, lipid profile, blood pressure and insulin requirement in a patient with type 1 diabetes mellitus
- Management of Vipadika with Mahisha Gritha Padanimajjana – a case report
