A simple turbidimetric flow injection system for saccharin determination in sweetener products
-
Camila Mendes
,
Emiliane Laignier
Abstract
A new method for saccharin determination in liquid sweetener products was developed. The method is based on the precipitation reaction of Ag(I) ions with saccharin in aqueous medium (pH 3.0), using a flow injection analysis system with merging zones, the suspension was stabilized with 5 g L−1 Triton X-100. All experimental parameters influencing the flow injection system were optimized by means of chemometric approaches. The linear analytical curve was built from 2.4 g L−1 up to 9.64 g L−1 (r = 0.9968) with a quantification limit of 2.40 g L−1. The precision assessed as relative standard deviation (n = 10) was found to be 1.75 % for the saccharin concentration of 7.20 g L−1. Based on interference studies performed with the substances commonly found in liquid sweeteners, such as sodium cyclamate, methylparaben, sodium aspartame, and benzoic and citric acids, at the analyte to interferent mole ratio of up to 1: 10, no interference with the saccharin determination was observed. The presence of chloride ions interferes with the method, but a preceding liquid-liquid saccharin extraction with ethyl acetate was successfully employed to overcome this drawback. Accuracy of the method in sweetener products was evaluated by a comparison with the HPLC method.
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© 2009 Institute of Chemistry, Slovak Academy of Sciences
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Artikel in diesem Heft
- A proposal of reference values for relative uncertainty increase in spectrophotometric analysis of pharmaceutical formulations
- Spectrophotometric quantification of fluoxetine hydrochloride: Application to quality control and quality assurance processes
- A simple turbidimetric flow injection system for saccharin determination in sweetener products
- Determination of metoprolol tartrate by capillary isotachophoresis
- Model predictive control of a CSTR: A hybrid modeling approach
- Application of extended NRTL equation for ternary liquid-liquid and vapor-liquid-liquid equilibria description
- Synthesis, DNA binding, and antimicrobial studies of novel metal complexes containing a pyrazolone derivative Schiff base
- Synthesis, spectral and electrochemical study of coordination molecules Cu4OX6L4: 4-cyanopyridine Cu4OBrnCl(6−n)(4-CNpy)4 complexes
- Synthesis, spectral and electrochemical study of coordination molecules Cu4OX6L4: 3-cyanopyridine Cu4OBrnCl(6−n)(3-CNpy)4 complexes
- Deposition and release of chlorhexidine from non-ionic and anionic polymer matrices
- Synthesis of new antimicrobial 4-aminosubstituted 3-nitrocoumarins
- Spectroscopic characterization of halogen- and cyano-substituted pyridinevinylenes synthesized without catalyst or solvent
- Chemical composition and antimicrobial activity of Erodium species: E. ciconium L., E. cicutarium L., and E. absinthoides Willd. (Geraniaceae)
- Photo-Fenton and photo-Fenton-like processes for the degradation of methyl orange in aqueous medium: Influence of oxidation states of iron
- Voltammetry of resazurin at a mercury electrode
- Effect of dielectric medium on angiotensin converting enzyme inhibitors binding to Zn2+
- HPLC analysis of a syrup containing nimesulide and its hydrolytic degradation product
