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Appropriate utilization of clinical laboratory tests
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María Concepción Alonso-Cerezo
Veröffentlicht/Copyright:
28. Oktober 2009
Abstract
Background: The use of laboratory tests has been increasing in recent years due to various factors affecting laboratories, physicians, legal aspects, or patients themselves.
Methods: The efficacy of laboratory tests must be evaluated on the basis of the clinical benefits that they provide in terms of prevention, diagnosis, follow-up, or treatment; with the aim of optimizing health results in general.
Results: There are techniques that can be used to determine the clinical validity of the efficacy, effectiveness, and safety of treatment or preventive measures performed on individuals with abnormal tests, as well as providing an economic evaluation of the process. Once the test is incorporated into clinical service, it must be evaluated by retrospective audits in test utilization. To improve the use of laboratory tests, many strategies have been devised that incorporate clinical practice guidelines (CPGs), the conduct of professionals and the patients, and organization of the process. We discuss the importance of the involvement of health professionals.
Conclusions: Strategies in relation to CPGs, conduct of professionals, conduct of patients, or organization of health care processes improve the use of tests in relation to clinical processes. Laboratory professionals have the appropriate knowledge and can improve the quality and efficacy of health care.
Clin Chem Lab Med 2009;47:1461–5.
Received: 2009-3-28
Accepted: 2009-8-14
Published Online: 2009-10-28
Published in Print: 2009-12-01
©2009 by Walter de Gruyter Berlin New York
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Artikel in diesem Heft
- Review
- Multiple gene interaction and modulation of hemostatic balance
- Minireview
- Appropriate utilization of clinical laboratory tests
- Genetics and Molecular Diagnostics
- Quantitation of RNA decay in dried blood spots during 20 years of storage
- ROS1 Asp2213Asn polymorphism is not associated with coronary artery disease in a Greek case-control study
- Association of glutathione-S-transferase polymorphisms with atopic dermatitis risk in preschool age children
- Haplotype-based association of regulator of G-protein signaling 5 gene polymorphisms with essential hypertension and metabolic parameters in Chinese
- A new automated human leukocyte antigen genotyping strategy to identify DR-DQ risk alleles for celiac disease and type 1 diabetes mellitus
- General Clinical Chemistry and Laboratory Medicine
- Serum thyrotropin and free thyroxine reference ranges as defined in a disease-free sample of French middle-aged adults
- Screening for M-proteinemia: serum protein electrophoresis and free light chains compared
- Temporal profile and clinical significance of serum neuron-specific enolase and S100 in ischemic and hemorrhagic stroke
- Salivary neuron specific enolase: an indicator for neuronal damage in patients with ischemic stroke and stroke-prone patients
- Antibodies to mutated citrullinated vimentin and antibodies to cyclic citrullinated peptides in juvenile idiopathic arthritis
- Age-associated developmental changes in the activated partial thromboplastin time (APTT) and causes of prolonged APTT values in healthy Chinese children
- Nucleated red blood cells and soluble transferrin receptor in thalassemia syndromes: relationship with global and ineffective erythropoiesis
- Serum chitotriosidase enzyme activity in patients with Crimean-Congo hemorrhagic fever
- Preanalytical mistakes in samples from primary care patients
- Should kidney tubular markers be adjusted for urine creatinine? The example of urinary cystatin C
- Validation and Outcome Studies
- Development and analytical performance evaluation of an automated chemiluminescent immunoassay for pro-gastrin releasing peptide (ProGRP)
- Development and validation of a liquid chromatography-tandem mass spectrometry assay for serum 25-hydroxyvitamin D2/D3 using a turbulent flow online extraction technology
- Letters to the Editor
- Lack of association between eNOS Glu298Asp gene polymorphism and carotid atherosclerosis in a Serbian population
- Falsely elevated troponin I attributed to collection tubes using the Vitros ECiQ system
- Processing effects and storage conditions on A Disintegrin And Metalloprotease (ADAM12s), a maternal serum marker for adverse pregnancy outcome
- Serum γ-glutamyltransferase: linking together environmental pollution, redox equilibria and progression of atherosclerosis?
- The impact factor for evaluating scientists: the good, the bad and the ugly
- Acknowledgement
- Acknowledgement
- Contents
- Contents, Volume 47, 2009
- Author Index
- Author Index
- Subject Index
- Subject Index
Schlagwörter für diesen Artikel
appropriate use;
efficacy;
improvement;
laboratory professionals;
laboratory results
Artikel in diesem Heft
- Review
- Multiple gene interaction and modulation of hemostatic balance
- Minireview
- Appropriate utilization of clinical laboratory tests
- Genetics and Molecular Diagnostics
- Quantitation of RNA decay in dried blood spots during 20 years of storage
- ROS1 Asp2213Asn polymorphism is not associated with coronary artery disease in a Greek case-control study
- Association of glutathione-S-transferase polymorphisms with atopic dermatitis risk in preschool age children
- Haplotype-based association of regulator of G-protein signaling 5 gene polymorphisms with essential hypertension and metabolic parameters in Chinese
- A new automated human leukocyte antigen genotyping strategy to identify DR-DQ risk alleles for celiac disease and type 1 diabetes mellitus
- General Clinical Chemistry and Laboratory Medicine
- Serum thyrotropin and free thyroxine reference ranges as defined in a disease-free sample of French middle-aged adults
- Screening for M-proteinemia: serum protein electrophoresis and free light chains compared
- Temporal profile and clinical significance of serum neuron-specific enolase and S100 in ischemic and hemorrhagic stroke
- Salivary neuron specific enolase: an indicator for neuronal damage in patients with ischemic stroke and stroke-prone patients
- Antibodies to mutated citrullinated vimentin and antibodies to cyclic citrullinated peptides in juvenile idiopathic arthritis
- Age-associated developmental changes in the activated partial thromboplastin time (APTT) and causes of prolonged APTT values in healthy Chinese children
- Nucleated red blood cells and soluble transferrin receptor in thalassemia syndromes: relationship with global and ineffective erythropoiesis
- Serum chitotriosidase enzyme activity in patients with Crimean-Congo hemorrhagic fever
- Preanalytical mistakes in samples from primary care patients
- Should kidney tubular markers be adjusted for urine creatinine? The example of urinary cystatin C
- Validation and Outcome Studies
- Development and analytical performance evaluation of an automated chemiluminescent immunoassay for pro-gastrin releasing peptide (ProGRP)
- Development and validation of a liquid chromatography-tandem mass spectrometry assay for serum 25-hydroxyvitamin D2/D3 using a turbulent flow online extraction technology
- Letters to the Editor
- Lack of association between eNOS Glu298Asp gene polymorphism and carotid atherosclerosis in a Serbian population
- Falsely elevated troponin I attributed to collection tubes using the Vitros ECiQ system
- Processing effects and storage conditions on A Disintegrin And Metalloprotease (ADAM12s), a maternal serum marker for adverse pregnancy outcome
- Serum γ-glutamyltransferase: linking together environmental pollution, redox equilibria and progression of atherosclerosis?
- The impact factor for evaluating scientists: the good, the bad and the ugly
- Acknowledgement
- Acknowledgement
- Contents
- Contents, Volume 47, 2009
- Author Index
- Author Index
- Subject Index
- Subject Index
