Reviews on Environmental Health

Editor-in-Chief: David O. Carpenter
Edited by: Tahir Rafique and Alexander Sergeev

Language: English

First published: January 1, 1986

Publication Frequency: 4 issues per year

View latest issue

Published by

Become an author with De Gruyter Brill

Submit Manuscript Author Information Explore this Subject

About this journal

Objective
Reviews on Environmental Health (REVEH) is an international peer-reviewed journal that aims to fill the need for publication of review articles on hot topics in the field of environmental health. It is intended to be an inspiring forum for scientists, environmentalists, physicians, engineers, and students who are concerned with aspects of human health, including quality of life, that are determined by physiological and psychosociological interactions between humans and physical, chemical, biological, and social factors in the environment. One major challenge is to link the research on environmental causes of disease to the clinical practice of medicine.
REVEH is a hybrid journal, published quarterly in print and online. All contributions submitted for publication in REVEH are subject to single-anonymized peer review by at least two experts in the field, selected and invited by the Editor-in-Chief and a dedicated Editorial Team. REVEH publishes only English-language articles.

Topics
Environmental toxicology // Neurotoxicology // Immunology // Oncology // Dermatology // Epidemiology // Molecular biology // Pharmacogenetics // Child health // Medicine, occupational health and risk assessment // Water, air, and soil quality control // Climate change// Methods for biomonitoring and remediation

Article formats
Review, Opinion Paper, Point/Counterpoint Paper, Letter to the Editor and Reply, Editorial

Your Benefits

Specialized, comprehensive and cutting-edge review articles
Interdisciplinary approach to the subject matter
High quality peer-review
Listed in major indexing setrvices such as SCIE, PubMed or Scopus
Each article easily discoverable because of Search Engine Optimization (SEO) and comprehensive abstracting and indexing services
Secure archiving by De Gruyter and the independent archiving service Portico
Authors have the option of publishing their articles under the Creative Commons Attribution (CC-BY-4.0) open access license. Open access allows authors to retain copyright and share their findings with the scientific community without restrictions. Authors who belong to an institution that has an agreement with the publisher can publish open access without paying an article processing charge (APC) or at a considerable discount

Requires Authentication Unlicensed
Licensed

m6A methylation – a new target of metabolic diseases induced by environmental pollutants

September 26, 2025

Runfeng Chang, Jinyun Li, Lu Fang, Miaocui Xi, Yue Huang, Jiahang Li, Wenjun Zhang, Qiuhui Qian, Zejun Wang, Jin Yan, Huili Wang

Download PDF

Exposure to environmental pollutants is closely associated with the development of obesity and related metabolic diseases. As the most prevalent form of eukaryotic chemical modification, N6-methyladenosine (m6A) methylation regulated by series enzymes plays an important role in the pathogenesis of metabolic diseases such as obesity, non-alcoholic fatty liver disease (NAFLD), atherosclerosis (AS), and type 2 diabetes (T2D). Therefore, investigating the specific mechanisms of m6A methylation in obesity and related metabolic diseases and its relationship with environmental pollutants is vital for developing treatment and prevention strategies. This article summarizes the latest research on m6A methylation in glucose and lipid metabolism-related diseases and elucidates the specific molecular mechanisms of metabolic disorders regulated by m6A methylation-related enzymes. More importantly, we highlight that m6A methylation process is a target for environmental pollutants in inducing human metabolic diseases. Our review aims to provide new insights into understanding the underlying mechanisms of environmental pollutant-induced metabolic diseases and to explore preventive and therapeutic measures.
Requires Authentication Unlicensed
Licensed

Prenatal exposure to bisphenol-A and neurocognitive changes in children aged 2 to 5 years: a systematic review

August 5, 2025

Isabella Vian Matias de Oliveira, Fernanda Martins de Albuquerque, Amanda de Jesus Fernandes, Priscila Berti Zanella, Mariane Alves Silva

Download PDF

Bisphenol-A (BPA) is a synthetic organic compound considered an endocrine disruptor. Childhood exposure to BPA has been linked to impaired memory and learning, as well as Attention Deficit Hyperactivity Disorder. The aim of this study was to review the available literature on prenatal exposure to BPA and its relationship to the neurocognitive development of children aged 2–5 years. This systematic review (CRD42023494940 registration PROSPERO) was conducted between December 2023 and May 2024, following the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) guidelines. The Web of Science, Embase, and PubMed databases were used for the search, with no publication date limit. The following terms, with the respective Boolean operators, were searched: ((bisphenol A) OR (BPA)) AND ((pregnancy) OR (pregnant woman)). Twenty-one longitudinal studies were selected for this review. Most studies have demonstrated negative effects of prenatal BPA exposure on the neurocognitive development of children aged 2–5 years. These results differed between the sexes, with females having lower emotional control, reduced language dominance and problem solving, and males having lower psychomotor development and higher prosocial behavior, among other differences. Overall, BPA exposure during pregnancy has been associated with hyperactivity, aggression, anxiety, depression, inattention, and sleep problems. It is concluded that maternal exposure to BPA during pregnancy results in adverse health effects in children aged 2–5 years, with impairments in their neurocognitive development.
Open Access
Genetic susceptibility to adverse arsenic-related cardiometabolic outcomes: a systematic review

June 27, 2025

Kim R. van Daalen, Jeenan Kaiser, Nusrat Khan, Maša Josipović, Clare T. Oliver-Williams, Adam S. Butterworth

Download PDF

Millions of people worldwide are chronically exposed to environmental arsenic through drinking water, increasing their risk of various adverse cardiometabolic outcomes. To understand the inter-individual variation in arsenic susceptibility, this systematic review explores all epidemiological evidence on interactions between single nucleotide polymorphisms (SNPs) and arsenic exposure in relation to cardiometabolic health. Five electronic databases were searched until April 2023. From 42,202 retrieved publications, 18 candidate gene-environment (cGxE) studies were included, and no genome-wide association studies were found. Of 676 SNPs in 148 genes tested, 40 SNPs in 24 genes, 4 haplotypes and combined SNPs in MCP-1/APOE , were reported to statistically significantly interact with arsenic exposure. These genes were involved in arsenic metabolism , oxidative stress or defence, DNA damage repair, endothelial (dys) function, inflammation or immune function, tumour suppressor activity, or were previously implicated in cardiometabolic disease pathways. Most studies did not explore the same SNPs (or strong proxies), and none of the identified SNP-arsenic interactions were replicated for the same arsenic species and cardiometabolic outcome. Whilst some SNPs are suggestive of influencing susceptibility to arsenic for various cardiometabolic outcomes, further research is needed to understand the interplay between arsenic and genetic variants, identify at-risk populations, and improve risk assessment.
Open Access
Exposure to air pollution from coal-fired power plants and impacts on human health: a scoping review

March 6, 2025

Nomfundo Mahlangeni, Thandi Kapwata, Candice Webster, Chantelle Howlett-Downing, Caradee Y. Wright

Download PDF

Communities living in proximity to coal-fired power plants (CFPPs) may be at greater risk of negative health impacts from exposure to air pollution than communities living further away. The aim of this scoping review was to provide an update on the evidence of the health risks of air pollution exposure associated with living in proximity to CFPPs and to evaluate the relationship between residential proximity and the extent of the health burden. We followed the PRISMA-ScR guidelines and searched Google Scholar, PubMed, ScienceDirect, Scopus and Web of Science for relevant studies from inception up to 31 January 2024. Fifty-six studies were included with most articles published from 2016 to 2023 (n=33, 59 %) and 35 were in high income countries (63 %). Living close to CFPPs was frequently associated with increased odds or likelihood of respiratory disorders, adverse birth outcomes and child developmental issues. Interventions such as emission control systems or total shutdown of CFPPs led to improved health among communities living near CFPPs. The review highlights the health impacts from air pollution associated with living in proximity to CFPPs and the need for policy measures to reduce air pollution by installing emission control technologies or transitioning to cleaner energy sources.
Publicly Available
Corrigendum to: Reliable disease biomarkers characterizing and identifying electrohypersensitivity and multiple chemical sensitivity as two etiopathogenic aspects of a unique pathological disorder

October 26, 2016

Dominique Belpomme, Christine Campagnac, Philippe Irigaray

Article number: 20158888

Download PDF
Requires Authentication Unlicensed
Licensed

Prevalence of foodborne pathogens in ready-to-eat foods: systematic review, meta-analysis and meta-regression

January 1, 2000

Pavel V. Berezhanskiy, Amirhossein Mahmoudizeh, Yadolah Fakhri

Download PDF

Ready-to-eat (RTE) foods are highly susceptible to microbial contamination, posing significant public health risks. This study aimed to conduct a systematic review, meta-analysis, and meta-regression to evaluate the prevalence of foodborne pathogens in RTE foods, assess trends over time, and examine the impact of the Global Food Security Index (GFSI). The search was conducted across Scopus, Web of Science, Embase, and PubMed until 2025. Studies reporting pathogen prevalence in RTE foods were included. Meta-analysis in defined subgroup and meta-regression assessed the effects of time and GFSI on prevalence trends. Sixty-five papers with 858 datasets comprising a total of 232,760 samples were included in the meta-analysis. Gram-negative pathogens (ES=18.32, 95 % CI: 15.29–21.53) were more prevalent than Gram-positive pathogens (ES=8.08, 95 % CI: 7.17–9.02). The African Region had the highest prevalence (ES=30.02, 95 % CI: 25.75–34.44), while the Americas had the lowest (ES=4.56, 95 % CI: 2.28–7.34). Contamination increased over time (C=0.018, p<0.001) but decreased with GFSI implementation (C=−0.005, p<0.001). RTE foods are highly vulnerable to contamination, particularly by Gram-negative pathogens. Regional disparities highlight the need for improved food safety infrastructure, especially in high-risk areas. Adopting global standards like GFSI and addressing emerging challenges such as antimicrobial resistance and climate change are essential for reducing foodborne illnesses.
Requires Authentication Unlicensed
Licensed

Fine particulate matter exposure and cancer risk: a systematic review and meta-analysis of prospective cohort studies

January 1, 2000

Yuting Feng, Jiaoyuan Li, Yi Wang, Tongxin Yin, Qiankun Wang, Liming Cheng

Download PDF

Studies examining the relationship between fine particulate matter (PM 2.5 ) exposure and cancer risk is inconclusive, with an evident scarcity of comprehensive data on the overall cancer risk. Given the emergence of new evidence, updated meta-analyses is essential. A search was performed on multiple databases including PubMed, Embase, Scopus, Web of Science, and the Cochrane Library up to Jan 2025. Hazard ratios (HRs), relative risks (RRs), or incidence rate ratios (IRRs) with their 95 % confidence intervals (CIs) were extracted and pooled. Moreover, a comprehensive and detailed quality assessment of the included studies was conducted to validate the plausibility of the findings. Overall, 57 original studies were included, covering 36 cancer categories and including overall cancer and malignancies specific to particular anatomical sites. For each increase of 10 μg per cubic meter in PM 2.5 concentration, there was an observed pooled HR of 1.07 for overall cancer (95 %CI:1.02–1.13). In the case of site-specific cancers, the pooled HRs were 1.11 (95 %CI:1.07–1.15), 1.06 (95 %CI:1.02–1.11), 1.17 (95 %CI:1.07–1.28), and 1.14 (95 %CI:1.03–1.26) for lung, breast, liver and esophageal cancers, respectively. Furthermore, PM 2.5 exposure may potentially correlate with the risk of cancers at other anatomical locations including upper aerodigestive tract, oral cavity, kidney, skin, as well as digestive organs. In light of available evidence, it is inferred that PM 2.5 exposure could potentially raise overall cancer risk with moderate certainty. As for site-specific malignancies, there is very low certainty evidence for lung cancer, low certainty evidence for breast cancer, and moderate certainty evidence for both liver and esophageal cancers.
Open Access
The effects of bushfire smoke exposure on oxidative stress and inflammatory biomarkers: a systematic review

January 1, 2000

Siti Nurshahida Nazli, Gaurav Langan, Sophie Iles, Leron Rathnayake, Dhiya Rampersad, Iyanuoluwa Araba, Peter D. Sly, Dwan Vilcins

Download PDF

Introduction Bushfire smoke (BFS) is an escalating global health concern, with increasing bushfire frequency due to climate change. Exposure to BFS significantly impacts public health due to worsening respiratory and cardiovascular conditions, causing increased of hospitalizations and mortality. While BFS exposure is linked to morbidity of these conditions, the underlying biological mechanisms, particularly oxidative stress and inflammation, remain unclear. Content This systematic review (PROSPERO ID: CRD42024554409) synthesized evidence on oxidative stress and inflammatory biomarkers from BFS exposure. Comprehensive searches of PubMed, Embase, Web of Science, Scopus, and Cochrane Library were conducted. Fourteen studies met inclusion criteria, encompassing occupational and non-occupational populations. Risk of bias was assessed using NIH tools, and findings were synthesized narratively due to study heterogeneity. Commonly examined biomarkers included IL-8, IL-6, TNF- α , 8-isoprostane, malondialdehyde (MDA), and 8-hydroxy-2′-deoxyguanosine (8-OHdG). Summary IL-8 emerged as the most consistent inflammatory biomarker, with a pooled random-effects analysis of three firefighter studies showing an acute post-shift increase in blood IL-8 (mean difference 9.76 pg/mL, 95 % CI –8.26 to 27.79), though with substantial heterogeneity. Other inflammatory and oxidative stress biomarkers showed mixed or inconsistent associations with BFS exposure. Small sample sizes, heterogeneous exposure assessment, inconsistent exposure metrics, and unadjusted confounding limited generalizability. Outlook This review identifies IL-8 as the most consistent short-term biomarker of BFS exposure in occupational settings but highlights inconsistent evidence for other biomarkers. Future research should use standardized biomarker protocols, larger sample size, longitudinal designs, and include vulnerable populations to clarify biomarker responses to BFS and strengthen the evidence base for public health and occupational safety measures.
Requires Authentication Unlicensed
Licensed

Triazole fungicides induce genotoxicity via oxidative stress in mammals in vivo: a comprehensive review

January 1, 2000

Lucas Vilas Bôas Correia, Gabriel Carvalhal de Aguiar, Aparecida Marta Regina dos Santos Pereira, Lucas de Santana Cardoso Thomaz, Isabelly Cristina Correia dos Santos de Oliveira, Renata de Britto Mari, Juliana Elaine Perobelli, Daniel Araki Ribeiro, Regina Cláudia Barbosa da Silva

Download PDF

This systematic review aimed to assess the genotoxic effects of triazole compounds authorized for use in Brazil in in vivo studies involving mammalian tissues and organs. A comprehensive search was conducted in specialized literature databases, including Embase, Google Scholar, Medline, PubMed, and Scopus using the following keywords: “triazoles,” “mutagenicity,” “genotoxicity,” “mammals,” “mammalian cells,” “eukaryotic cells,” “rodents,” “rats,” “mice,” and “ in vivo ” for all data published until February 2025. A total of 15 studies were included. The findings demonstrated that exposure to triazole fungicides (BRO, DFC, EPX, PPZ and TEB) induce genotoxicity in different mammalian tissues or organs in vivo . This genotoxic effect was manifested through various biological alterations, including increased DNA damage, the formation of micronuclei and adducts, as well as elevated rates of genetic mutations. Furthermore, these chemicals demonstrated the ability to induce oxidative stress, suggesting that this mechanism plays a central role in the genotoxicity associated with these chemicals. This review demonstrated that triazole fungicides induce genotoxicity in mammalian tissues and organs in vivo , with oxidative stress acting as a possible key mechanism in this process. Additionally, these findings underscore the importance of maintaining national pesticide residue monitoring programs (PARA), promoting good agricultural practices, and enforcing maximum residue limit (MRLs) programs, as well as conducting further research on the chronic effects of triazole fungicides, particularly among vulnerable populations in Brazil and worldwide. Such measures are crucial for safeguarding human health and protecting the environment.

Journal Impact Factor	4.5	2024, Journal Citation Reports (Clarivate, 2025)
5-year Journal Impact Factor	4.8	2024, Journal Citation Reports (Clarivate, 2025)
Journal Citation Indicator	0.47	2024, Journal Citation Reports (Clarivate, 2025)
CiteScore	10.2	2024, Scopus (Elsevier B.V., 2025)
SCImago Journal Rank	0.956	2024, SJR (Scimago Lab, 2025; Data Source: Scopus)
Source Normalized Impact per Paper	1.383	2024, CWTS Journal Indicators (CWTS B.V., 2025; Data Source: Scopus)

Reviews on Environmental Health

Overview

About this journal

Your Benefits

Ahead of Publication / Just Accepted

Issues

Ranking

Submit

Editorial

Abstracting and Indexing

Supplementary Materials

Supplementary Materials

Topics

Topics

External Links

Bibliographic data