How much is enough? Evaluation of adrenal function in children who undergo growth hormone stimulation test
Abstract
The objective was to determine the probability of receiving steroid treatment following an insulin tolerance test (ITT) for short-stature evaluation and to evaluate the utility of a subsequent cortrosyn stimulation test (CST) in determining adrenal sufficiency. We retrospectively analyzed the hypothalamic-pituitary-adrenal (HPA) axis evaluation in short-stature subjects during the 5-year period from January 2005 to December 2009. The probability of receiving steroid treatment was <10% when the maximum cortisol concentration during an ITT was <8.4 μg/dL. In the event of a suboptimal cortisol response during an ITT, only a single 1-μg CST is recommended for assessment of adrenal function.
©2012 by Walter de Gruyter Berlin Boston
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Artikel in diesem Heft
- Masthead
- Masthead
- Editorial
- Obesity, adolescence, and sleep deprivation
- Reviews
- 18F-DOPA positron emission tomography/computed tomography application in congenital hyperinsulinism
- Pathogenesis of propylthiouracil-related hepatotoxicity in children: present concepts
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- Original articles
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- Effects of selenium supplementation in the early stage of autoimmune thyroiditis in childhood: an open-label pilot study
- Overestimation of final height prediction in patients with classical congenital adrenal hyperplasia using the Bayley and Pinneau method
- Is the growth outcome of children with idiopathic short stature and isolated growth hormone deficiency following treatment with growth hormone and a luteinizing hormone-releasing hormone agonist superior to that obtained by GH alone?
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- Association of vitamin D receptor gene Cdx2 polymorphism with bone markers in Turner syndrome patients
- Serum 25-hydroxyvitamin D levels do not correlate with asthma severity in a case-controlled study of children and adolescents
- Assessment of the 21-hydroxylase deficiency and the adrenal functions in young females with Turner syndrome
- The association of FGF23 levels in obese adolescents with insulin sensitivity
- Higher postprandial serum ghrelin among African-American girls before puberty
- Metabolic impact of a ketogenic diet compared to a hypocaloric diet in obese children and adolescents
- The second report from Turkey: waist percentiles for 6–11-year-old children in Elazig Province, Eastern Anatolia
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- Nesfatin-1 in newborns: relationship with endocrine and metabolic and anthropometric measures
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- A novel mutation in the GCM2 gene causing severe congenital isolated hypoparathyroidism
- Relation among ghrelin, nutritional status, and immunity in children
- The histopathological effects of tamoxifen in the treatment of pubertal gynecomastia
- Patient reports
- Central precocious puberty after interpersonal transfer of testosterone gel: just a coincidence?
- Elevated α-fetoprotein levels in Van Wyk-Grumbach syndrome: a case report and review of literature
- Identification of LDLR mutations in two Chinese pedigrees with familial hypercholesterolemia
- Foster care and type 1 diabetes in the Bronx: a case series
- Primary hyperparathyroidism: fifth parathyroid intrathymic adenoma in a young patient
- Sturge-Weber syndrome: presentation with partial hypopituitarism
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- First case report of short-chain acyl-CoA dehydrogenase deficiency in China
- Ganglioneuroblastoma in a young child with Turner syndrome
- MODY2 caused by a novel mutation of GCK gene
- Variability in the age at diagnosis of diabetes in two unrelated patients with a homozygous glucokinase gene mutation
- Letter to the editor
- Understanding less than nothing: high-dose vitamin D therapy for treating vitamin D deficiency
- Meetings
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