Abstract
The conjugate hydrocyanation of α-cyanoacrylates through chemoselective 1,4-addition to synthesise α,β-dicyanopropanoates by one-pot two-step procedure using potassium hexacyanoferrate(II) as an eco-friendly cyanide source, benzoyl chloride as a promoter and potassium carbonate as a catalyst is described. The advantages of this protocol are use of a non-toxic, non-volatile and inexpensive cyanating reagent, high product yields and simple working procedure
References
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© 2015 Institute of Chemistry, Slovak Academy of Sciences
Articles in the same Issue
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Articles in the same Issue
- Liquid–liquid extraction and cloud point extraction for spectrophotometric determination of vanadium using 4-(2-pyridylazo)resorcinol
- Sensitive and selective determination of peptides, PG and PGP, using a novel fluorogenic reagent 4-chlorobenzene-1,2-diol
- Spectroscopy studies of sandwich-type complex of silver(I) co-ordinated to nuclear fast red and adenine and its analytical applications
- Differentiation of selected blue writing inks by surface-enhanced Raman spectroscopy
- A simple pyridine-based colorimetric chemosensor for highly sensitive and selective mercury(II) detection with the naked eye
- Phospho sulfonic acid as efficient heterogeneous Brønsted acidic catalyst for one-pot synthesis of 14H-dibenzo[a,j ]xanthenes and 1,8-dioxo-octahydro-xanthenes
- Microfiltration of post-fermentation broth with backflushing membrane cleaning
- Mass transfer examination in electrodialysis using limiting current measurements
- Determination of diffusivity from mass transfer measurements in a batch dialyzer: numerical analysis of pseudo-steady state approximation
- Structural and thermal characterization of copper(II) complexes with phenyl-2-pyridylketoxime and deposition of thin films by spin coating
- Oxidation of 4-nitro-o-xylene with nitric acid using N-hydroxyphthalimide under phase transfer conditions
- Synthesis of pyranopyrazoles, benzopyrans, amino-2-chromenes and dihydropyrano[c]chromenes using ionic liquid with dual Brønsted acidic and Lewis basic sites
- Eco-friendly conjugate hydrocyanation of α-cyanoacrylates using potassium hexacyanoferrate(II) as cyanating reagent
- Morphological orders of spherulitic crystal textures in Belousov–Zhabotinsky-type oscillatory reaction system
- Zwitterionic structures of selenocysteine-containing dipeptides and their interactions with Cu(II) ions