Highlight: Of Systems and Structures

Artikel in diesem Heft

1. Guest Editorial
2. Highlight: Of Systems and Structures
3. HIGHLIGHT: STRUCTURAL SYSTEMS BIOLOGY
4. Converging on the function of intrinsically disordered nucleoporins in the nuclear pore complex
5. Towards molecular systems biology of gene transcription and regulation
6. Small-angle X-ray and neutron scattering as a tool for structural systems biology
7. The type III secretion injectisome, a complex nanomachine for intracellular ‘toxin’ delivery
8. Structural insights into the evolution of the adaptive immune system: the variable lymphocyte receptors of jawless vertebrates
9. The XPD helicase: XPanDing archaeal XPD structures to get a grip on human DNA repair
10. Decoding transcription and microRNA-mediated translation control in Drosophila development
11. Human SepSecS or SLA/LP: selenocysteine formation and autoimmune hepatitis
12. PROTEIN STRUCTURE AND FUNCTION
13. The rhodanese RhdA helps Azotobacter vinelandii in maintaining cellular redox balance
14. MEMBRANES, LIPIDS, GLYCOBIOLOGY
15. The membrane-bound bile acid receptor TGR5 (Gpbar-1) is localized in the primary cilium of cholangiocytes
16. CELL BIOLOGY AND SIGNALING
17. miR-221/222 suppression protects against endoplasmic reticulum stress-induced apoptosis via p27^Kip1- and MEK/ERK-mediated cell cycle regulation
18. Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway
19. Sprouty4 levels are increased under hypoxic conditions by enhanced mRNA stability and transcription
20. PROTEOLYSIS
21. Degradation of human kininogens with the release of kinin peptides by extracellular proteinases of Candida spp.
22. NOVEL TECHNIQUES
23. Detection of breast cancer-related antigens through cDNA phage-displayed protein microarray