Nutrigenomics – 2006 update
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Jim Kaput
Abstract
The Human Genome and HapMap projects have provided the tools and information that will aid in understanding how nutrients alter the expression of an individual's genetic information and why individuals differ in metabolism of foods at the molecular level. The study of how genes and gene products interact with dietary chemicals to alter phenotype and, conversely, how genes and their products metabolize nutrients is called nutritional genomics or “nutrigenomics.” This new field has received considerable attention in the last 6 years, most of which has been on the promise rather than on scientific results from nutrigenomic experiments. Funding for nutrigenomics research focused primarily on individual laboratory projects in the 1990s and early 2000s. The novelty of combining nutrition and genetics limited that funding to a relatively small number of laboratories. Only in the past 3 years have centers been funded to foster collaborations and conduct large-scale projects that are studying nutrient-gene interactions. The increase in interest and funding is beginning to generate the critical mass to realize the promise of nutritional genomics.
Clin Chem Lab Med 2007;45:279–87.
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©2007 by Walter de Gruyter Berlin New York
Artikel in diesem Heft
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- From human genetic variations to prediction of risks and responses to drugs and the environment
- Nutrigenomics – 2006 update
- How to comprehensively analyse proteins and how this influences nutritional research
- Genotypes, obesity and type 2 diabetes – can genetic information motivate weight loss? A review
- The Gene-Diet Attica Investigation on childhood obesity (GENDAI): overview of the study design
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- Emerging role of cathepsin S in obesity and its associated diseases
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- Clustered components of the metabolic syndrome and platelet counts in Japanese females
- International Standard for serum vitamin B12 and serum folate: international collaborative study to evaluate a batch of lyophilised serum for B12 and folate content
- Multicentre physiological reference intervals for serum concentrations of immunoglobulins A, G and M, complement C3c and C4 measured with Tina-Quant® reagents systems
- In vivo and in vitro allergy diagnostics: it's time to reappraise the costs
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- Meeting Report: From human genetic variations to prediction of risks and responses to drugs and the environment
