Startseite Unique supramolecular assembly of a synthetic achiral α, γ-hybrid tripeptide
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Unique supramolecular assembly of a synthetic achiral α, γ-hybrid tripeptide

  • Arpita Dutta EMAIL logo , Suven Das , Purak Das , Suvendu Maity , Prasanta Ghosh und Soumya Shankha Biswas
Veröffentlicht/Copyright: 7. März 2022
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Zeitschrift für Kristallographie - Crystalline Materials
Aus der Zeitschrift Zeitschrift für Kristallographie - Crystalline Materials Band 237 Heft 1-3

Abstract

An achiral tripeptide, namely, Boc-γ-Abu-m-ABA-Aib-OMe (γ-Abu: γ−amino butyric acid; m-ABA: meta-aminobenzoic acid) was synthesized by solution phase procedure. The α, γ-hybrid peptide was designed in such a way that two dissimilar γ−amino acids, one flexible and another rigid, were positioned sidewise along with α-amino isobutyric acid (Aib) as C-terminal residue. The single crystal X-ray diffraction analysis revealed that two kinks were generated around centrally placed m-ABA. Interestingly, the peptide self-assembled via three intermolecular N–H···O and one intermolecular C–H···O hydrogen bonding interactions to supramlecular helical architecture.

Keywords: γ-amino acid; m-aminobenzoic acid; self-assembly; tripeptide
Corresponding author: Arpita Dutta, Department of Chemistry, Rishi Bankim Chandra Evening College, Naihati, 24-Parganas (N), Pin-743165, India, E-mail:

Acknowledgments

AD acknowledges laboratory facilities at R. B. C. Evening College, Naihati. PD is greateful to SERB (DST), India for fellowship [No.TAR/2018/000228].

  1. Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

  2. Research funding: None declared.

  3. Conflict of interest statement: The authors declare no conflicts of interest regarding this article.

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Supplementary Material

The online version of this article offers supplementary material (https://doi.org/10.1515/zkri-2022-0002).

Received: 2022-01-14
Accepted: 2022-02-17
Published Online: 2022-03-07
Published in Print: 2022-03-28

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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  5. Inorganic Crystal Structures (Original Paper)
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https://doi.org/10.1515/zkri-2022-0002
Schlagwörter für diesen Artikel
γ-amino acid; m-aminobenzoic acid; self-assembly; tripeptide

Artikel in diesem Heft

  1. Frontmatter
  2. In this issue
  3. Micro Review
  4. Structural diversity among multinary pnictide oxides: a minireview focused on semiconducting and superconducting heteroanionic materials
  5. Inorganic Crystal Structures (Original Paper)
  6. The orthorhombic-to-monoclinic phase transition in NbCrP – Peierls distortion of the chromium chain
  7. Halide-sodalites: thermal expansion, decomposition and the Lindemann criterion
  8. RE3Rh2Sn4 (RE = Y, Gd–Tm, Lu) – first stannides with Lu3Co2In4 type structure
  9. Scandium–copper–indides deriving from the ZrNiAl and MnCu2Al type structures
  10. Syntheses, crystallographic characterization, and structural relations of Rb[SCN]
  11. Organic and Metalorganic Crystal Structures (Original Paper)
  12. Unique supramolecular assembly of a synthetic achiral α, γ-hybrid tripeptide
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