Article
Licensed
Unlicensed Requires Authentication

Silver-hydroxyapatite nanocomposites as bactericidal and fungicidal materials

  • , , , , , , and
Published/Copyright: June 11, 2013
Become an author with De Gruyter Brill
Submit Manuscript Author Information
International Journal of Materials Research
From the journal International Journal of Materials Research Volume 101 Issue 1

Abstract

Silver-hydroxyapatite nanocomposites containing 1 wt.% of metallic silver have been obtained by a colloidal chemical route and subsequent chemical reduction process. The silver nanoparticles are supported on the hydroxyapatite surface without a high degree of agglomeration. The bactericidal effect against common Gram-positive and Gram-negative bacteria, as well as antifungal activity against yeast have been investigated. The results indicated a high antimicrobial activity for E. coli, M. Luteus and I. Orientalis, so this material can be a promising antimicrobial biomaterial for implant and reconstructive surgery, among other applications.

Keywords: Hydroxyapatite; Silver; Nanocomposite; Antibacterial; Antifungal
* Correspondence address Pr. Ramón Torrecillas San Millán, Centro de Investigación en Nanomateriales y Nanotecnología, C.T. Materiales No Metalicos Parque Tecnologico de Asturias 33428, Llanera (Asturias), Spain. Tel.: +34 985 98 00 58 Ext.: 256, Fax: +34 985 26 55 74, E-mail:

References

[1] W.Suchanek, M.Yoshimura: J. Mater. Res.13 (1998) 94.10.1557/JMR.1998.0015Search in Google Scholar

[2] V.P.Orlovskii, V.S.Komlev, S.M.Barinov: Inorganica Materials8 (2002) 1159.Search in Google Scholar

[3] Y.Li, D.Li, Z.Xu: J. Mat. Sci.44 (2009) 1258.10.1007/s10853-008-3239-0Search in Google Scholar

[4] L.L.Hench: J. Am. Ceram. Soc.81 (1998) 1705.10.1111/j.1151-2916.1998.tb02540.xSearch in Google Scholar

[5] K.D.Johnson, K.E.Frierson, T.S.Keller, C.Cook, R.Scheinberg, J.Zerwekh, L.Meyers, M.F.Sciadini: J. of Orthopaedic Research14 (1996) 351. PMid:8676247;10.1002/jor.1100140304Search in Google Scholar

[6] W.Chen, Y.Liu, H.SCourtney, M.Bettenga, C.M.Agrawal, J.D.Bumgardner, J.L.Ong: Biomaterials27 (2006) 5512. PMid:16872671;10.1016/j.biomaterials.2006.07.003Search in Google Scholar

[7] S.Nasser: Orthopedic Clinics of North America (2) (1992) 265.10.1016/S0030-5898(20)31737-5Search in Google Scholar

[8] J.G.E.Hendriks, J.R.van Horn, H.C.van der Mei, H.J.Busscher: Biomaterials25 (2004) 545. PMid:14585704;10.1016/S0142-9612(03)00554-4Search in Google Scholar

[9] W.Chen, S.Oh, A.P.Ong, N.Oh, Y.Liu, H.S.Courtney, M.Appleford, J.L.Ong: J. Biomed. Mater. Res.: Part A84 (2007) 899.10.1002/jbm.a.31197Search in Google Scholar

[10] W.J.Leach, N.I.L.Wilson: J. Royal Coll. Surg. Edinb.37 (1992) 265.Search in Google Scholar

[11] T.N.Gerhart, R.D.Roux, P.A.Hanff, G.L.Horowitz, A.A.Renshaw, W.C.Hayes: J. Orthop. Res.11 (1993) 250. PMid:8483037;10.1002/jor.1100110212Search in Google Scholar

[12] J.G.E.Hendriks, J.R.van Horn, H.C.van der Mei, H.J.Bussche: Biomaterials25 (2004) 545. PMid:14585704;10.1016/S0142-9612(03)00554-4Search in Google Scholar

[13] M.J.Patzakis, J.H.Calhoun, G.Cierny, P.Holtom, J.T.Mader, C.L.Nelson:. Contemp. Orthop.28 (1994) 157.Search in Google Scholar

[14] S.L.Percival, P.G.Bowler, D.Russell: The Journal of hospital infection60 (2005) 1. PMid:15823649;10.1016/j.jhin.2004.11.014Search in Google Scholar

[15] W.Zhang, X.Qiao, J.Chen: Colloids and Surfaces A: Physicochemical and Engineering Aspects299 (2007) 22.10.1016/j.colsurfa.2006.11.012Search in Google Scholar

[16] Q.L.Feng, J.Wu, G.Q.Chen, F.Z.Cui, T.N.Kim, J.O.Kim: J. Biomed. Mater.52 (2000) 662. PMid:11033548;10.1002/1097-4636(20001215)52:4<662::AID-JBM10>3.0.CO;2-3Search in Google Scholar

[17] M.Rai, A.Yadav, A.Gade: Biotechnology Advances27 (2009) 76. PMid:18854209;10.1016/j.biotechadv.2008.09.002Search in Google Scholar

[18] H.Y.Song, K.K.Ko, L.H.Oh, B.T.Lee: Eur. Cells Mater.11 (2006) 58.Search in Google Scholar

[19] J.R.Morones, J.L.Elechiguerra, A.Camacho, J.T.Ramirez: Nanotechnology16 (2005) 2346.10.1088/0957-4484/16/10/059Search in Google Scholar

[20] I.Sondi, B.Salopek-Sondi: J. Colloid. Interface Sci.275 (2004) 177. PMid:15158396;10.1016/j.jcis.2004.02.012Search in Google Scholar

[21] A.Mo, J.Liao, W.Xu, S.Xian, Y.Li, S.Bai: Appl. Surf. Sci.255 (2008) 435.10.1016/j.apsusc.2008.06.083Search in Google Scholar

[22] M.Díaz, M.F.Barba, M.Miranda, F.Guitián, R.Torrecillas, J.S.Moya: Journal of Nanomaterials (2009) 498505.10.1155/2009/498505.Search in Google Scholar

[23] S.Thomas, S.K.Nair, E.M.A.Jamal, S.H.Al-Harthi, M.R.Varma, M.R.Anantharaman: Nanotechnology19 (2008) 075710.10.1088/0957-4484/19/7/075710Search in Google Scholar

[24] A.Esteban-Cubillo, C.Diaz, A.Fernandez, L.A.Diaz, C.Pecharroman, R.Torrecillas, J.S.Moya: J. Eur. Ceram. Soc.26 (2006) 1.10.1016/j.jeurceramsoc.2004.10.029Search in Google Scholar

[25] S.K.Arumugan, T.P.Sastry, B.Sreedhar, A.B.Mandal: J. Biomed. Mater. Res. Part A80A (2007) 391.10.1002/jbm.a.30895Search in Google Scholar PubMed

[26] S.Pal, Y.K.Tak, J.M.Song: Appl. Environ. Microbiol.73 (2007) 1712. PMid:17261510; PMCid:1828795;10.1128/AEM.02218-06Search in Google Scholar PubMed PubMed Central

[27] A.PanácekL.Kvítek, R.Prucek, M.Kolár, R.Vecerová, N.Pizúrová, V.K.Sharma, T.Nevecná, R.Zboril: J. Phys. Chem. B110 (2006) 16248. PMid:16913750;10.1021/jp063826hSearch in Google Scholar PubMed

[28] L.Esteban-Tejeda, F.Malpartida, A.Esteban-Cubillo, C.Pecharromán, J.S.Moya: Nanotechnology20 (2009) 085103.10.1088/0957-4484/20/8/085103Search in Google Scholar PubMed

[29] A.Esteban-Cubillo, C.Pecharromán, E.Aguilar, J.Santarén, J.S.Moya: J. Mater. Sci.40 (2006) 5208.10.1007/s10853-006-0432-xSearch in Google Scholar

Received: 2009-4-13
Accepted: 2009-10-22
Published Online: 2013-06-11
Published in Print: 2010-01-01

© 2010, Carl Hanser Verlag, München

Articles in the same Issue

  1. Contents
  2. Contents
  3. Editorial
  4. Editorial
  5. The 7th International Workshop on Interfaces: New Materials via Interfacial Control
  6. Basic
  7. First principles based predictions of the toughness of a metal/oxide interface
  8. The role of interfaces in the behavior of magnetic tunnel junction structures
  9. Applications of aberration corrected scanning transmission electron microscopy and electron energy loss spectroscopy to thin oxide films and interfaces
  10. Van der Waals-London dispersion interaction framework for experimentally realistic carbon nanotube systems
  11. Determination of grain boundary potentials in ceramics: Combining impedance spectroscopy and inline electron holography
  12. Grain boundary plane distributions in aluminas evolving by normal and abnormal grain growth and displaying different complexions
  13. Theoretical study on the structure and energetics of intergranular glassy film in Si3N4-SiO2 ceramics
  14. Inter-granular glassy phases in the low-CaO-doped HIPed Si3N4 ceramics: a review
  15. Applied
  16. Sintering of fully faceted crystalline particles
  17. Grain growth kinetics and segregation in yttria tetragonal zirconia polycrystals
  18. A new method to measure monoclinic depth profile in zirconia-based ceramics from X-ray diffraction data
  19. The role of Si impurities in the transient dopant segregation and precipitation in yttrium-doped alumina
  20. Using microfabricated devices to determine the fracture strength of materials
  21. Spark plasma sintering of self-doped alumina powders
  22. High density carbon materials obtained at relatively low temperature by spark plasma sintering of carbon nanofibers
  23. Application of new forming and sintering techniques to obtain hydroxyapatite and β-TCP nanostructured composites
  24. Silver-hydroxyapatite nanocomposites as bactericidal and fungicidal materials
  25. Cu-Ni-YSZ anodes for solid oxide fuel cell by mechanical alloying processing
  26. Rapid transient-liquid-phase bonding of Al2O3 with microdesigned Ni/Nb/Ni interlayers
  27. DGM News
  28. Personal
https://doi.org/10.3139/146.110256
Keywords for this article
Hydroxyapatite; Silver; Nanocomposite; Antibacterial; Antifungal

Articles in the same Issue

  1. Contents
  2. Contents
  3. Editorial
  4. Editorial
  5. The 7th International Workshop on Interfaces: New Materials via Interfacial Control
  6. Basic
  7. First principles based predictions of the toughness of a metal/oxide interface
  8. The role of interfaces in the behavior of magnetic tunnel junction structures
  9. Applications of aberration corrected scanning transmission electron microscopy and electron energy loss spectroscopy to thin oxide films and interfaces
  10. Van der Waals-London dispersion interaction framework for experimentally realistic carbon nanotube systems
  11. Determination of grain boundary potentials in ceramics: Combining impedance spectroscopy and inline electron holography
  12. Grain boundary plane distributions in aluminas evolving by normal and abnormal grain growth and displaying different complexions
  13. Theoretical study on the structure and energetics of intergranular glassy film in Si3N4-SiO2 ceramics
  14. Inter-granular glassy phases in the low-CaO-doped HIPed Si3N4 ceramics: a review
  15. Applied
  16. Sintering of fully faceted crystalline particles
  17. Grain growth kinetics and segregation in yttria tetragonal zirconia polycrystals
  18. A new method to measure monoclinic depth profile in zirconia-based ceramics from X-ray diffraction data
  19. The role of Si impurities in the transient dopant segregation and precipitation in yttrium-doped alumina
  20. Using microfabricated devices to determine the fracture strength of materials
  21. Spark plasma sintering of self-doped alumina powders
  22. High density carbon materials obtained at relatively low temperature by spark plasma sintering of carbon nanofibers
  23. Application of new forming and sintering techniques to obtain hydroxyapatite and β-TCP nanostructured composites
  24. Silver-hydroxyapatite nanocomposites as bactericidal and fungicidal materials
  25. Cu-Ni-YSZ anodes for solid oxide fuel cell by mechanical alloying processing
  26. Rapid transient-liquid-phase bonding of Al2O3 with microdesigned Ni/Nb/Ni interlayers
  27. DGM News
  28. Personal
Downloaded on 14.4.2026 from https://www.degruyterbrill.com/document/doi/10.3139/146.110256/html
Scroll to top button