New substituted mono-and bis(imidazolyl)pyridines and their application in nitroaldolisation reaction
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R. Keder
,
P. Drabina
Abstract
New chiral nitrogen ligands based on the substituted mono-and bis(imidazolyl)pyridines have been prepared and characterised. Their complexes with cupric acetate were used as catalysts in the nitroaldolisation reaction. In the case of optically pure complexes of mono(imidazolyl)pyridine, the isolated products were 2-nitro-1-(2-nitrophenyl)ethanols or 2-nitro-1-(4-nitrophenyl)ethanols in overall yields of 49–93 % and with the maximum enantiomeric excess of 15.6 %. The complexes of bis(imidazolyl)pyridine also catalyse the nitroaldol reaction, the yields being 64–90 %, but with zero enantioselective excess.
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© 2006 Institute of Chemistry, Slovak Academy of Sciences
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Artikel in diesem Heft
- Influence of medium on the kinetics of oxidation of iron(II) ion with t-butyl hydroperoxide
- Synthesis of new thiazolo[2,3-b]pyrimidine derivatives of pharmaceutical interest
- Enthalpic analysis of the CaTiSiO5 system
- Kinetic, spectrophotometric determination of nanogram levels of manganese(II) using catalytic azo dye—potassium periodate—1,10-phenanthroline system
- Application of a ternary complex of tungsten(VI) with 4-nitrocatechol and thiazolyl blue for extraction-spectrophotometric determination of tungsten
- Determination of risperidone at picogram level in human urine by luminol—H2O2 chemiluminescence
- Electrochemical dissolution of chalcopyrite studied by voltammetry of immobilized microparticles
- Colon tissue concentrations of copper, iron, selenium, and zinc in colorectal carcinoma patients
- Structure of tetrakis(pyridinioacetate) neodymium(III) tetrahydrate perchlorate
- Thermally stable oligomer—Metal complexes based on oligo-ortho-aminophenol and oligophenylazomethinephenol
- Adsorption of SO2 on alumina
- One-pot, three-component synthesis of secondary amines and trisubstituted hydrazines from ketones
- Synthesis of α,α′-bis(R-benzylidene)cycloalkanones catalyzed by potassium hydrogen sulfate under solvent-free conditions
- Electrical conductivity of the molten KF—K2TaF7 system
- New substituted mono-and bis(imidazolyl)pyridines and their application in nitroaldolisation reaction
