Remote magnetically controlled drug release from electrospun composite nanofibers: design of a smart platform for therapy of psoriasis
Abstract
An efficient method for the large-scale fabrication of composite polyvinyl alcohol polymer nano fibers loaded with magnetic nanoparticles and methotrexate is reported in this study. We have demonstrated that nonwoven textile formed by needleless electro spinning is effective in immobilization and triggered the release of drugs, which is achieved by an alternating magnetic field induced heating of magnetic nanoparticles. This smart stimuli-responsive release ability, biocompatibility, and ultra-lightweight property render enormous potential for this electrospun nano fiber mat to be used as an anti-psoriatic drugs release platform, which may have far-reaching applications in dermatology.
Funding source: Agentúra na Podporu Výskumu a Vývoja
Award Identifier / Grant number: 16-0600
Funding source: Vedecká Grantová Agentúra MŠVVaŠ SR a SAV
Award Identifier / Grant number: 1/0810/18
Acknowledgement
This work was supported by Slovak Research and Development Agency APVV project No. 16-0600, and Slovak Grant Agency VEGA project No. 1/0810/18.
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© 2020 Walter de Gruyter GmbH, Berlin/Boston
Artikel in diesem Heft
- Frontmatter
- General
- Remote magnetically controlled drug release from electrospun composite nanofibers: design of a smart platform for therapy of psoriasis
- Dynamical Systems & Nonlinear Phenomena
- A modified simple chaotic hyperjerk circuit: coexisting bubbles of bifurcation and mixed-mode bursting oscillations
- Dynamics of a discrete-time system with Z-type control
- Dynamic response of axially loaded end-bearing rectangular closed diaphragm walls
- Hydrodynamics
- Admissibility conditions for Riemann data in shallow water theory
- Numerical study on the rotating electro-osmotic flow of third grade fluid with slip boundary condition
- Solid State Physics & Materials Science
- Ultrasonic study of Si-oil based magneto-rheological fluid
- Electromagnetic propagation characteristics of one-dimensional photonic crystals with metal layers in quasi-parity-time (PT)-symmetric system
- Thermodynamics & Statistical Physics
- Combined influence of axial electron temperature and exponential plasma density ramp on the self-focusing of a chirped laser in plasma
Artikel in diesem Heft
- Frontmatter
- General
- Remote magnetically controlled drug release from electrospun composite nanofibers: design of a smart platform for therapy of psoriasis
- Dynamical Systems & Nonlinear Phenomena
- A modified simple chaotic hyperjerk circuit: coexisting bubbles of bifurcation and mixed-mode bursting oscillations
- Dynamics of a discrete-time system with Z-type control
- Dynamic response of axially loaded end-bearing rectangular closed diaphragm walls
- Hydrodynamics
- Admissibility conditions for Riemann data in shallow water theory
- Numerical study on the rotating electro-osmotic flow of third grade fluid with slip boundary condition
- Solid State Physics & Materials Science
- Ultrasonic study of Si-oil based magneto-rheological fluid
- Electromagnetic propagation characteristics of one-dimensional photonic crystals with metal layers in quasi-parity-time (PT)-symmetric system
- Thermodynamics & Statistical Physics
- Combined influence of axial electron temperature and exponential plasma density ramp on the self-focusing of a chirped laser in plasma