Startseite Incidence and outcomes of women with Hodgkin’s lymphoma in pregnancy: a population-based study on 7.9 million births
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Incidence and outcomes of women with Hodgkin’s lymphoma in pregnancy: a population-based study on 7.9 million births

  • Amira El-Messidi , Valerie Patenaude , Ghaidaa Hakeem und Haim A. Abenhaim EMAIL logo
Veröffentlicht/Copyright: 19. August 2014
Journal of Perinatal Medicine
Aus der Zeitschrift Journal of Perinatal Medicine Band 43 Heft 6

Abstract

Objective: The purpose of our study was to estimate the incidence and maternal and fetal outcomes of Hodgkin’s lymphoma (HL) in pregnancy.

Methods: We carried out a population-based cohort study on all births identified in the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample from 2003 to 2011. We calculated disease incidence and used logistic regression analysis to estimate the adjusted effect of HL on maternal and neonatal outcomes.

Results: There were 638 cases of HL in pregnancy among 7,916,388 births, for an overall incidence of 8.06 per 100,000 births, with no perceivable trend over the 8-year study period. Relative to controls, HL in pregnancy was more common among Caucasians and women aged 25–34 years. After adjusting for baseline characteristics, women with HL in pregnancy were more likely to have preterm births, odds ratio (OR) 1.93 (1.53, 2.42) require postpartum blood transfusion, OR 1.38 (1.05, 1.82), and have venous thromboembolism (VTE), OR 7.93 (2.97, 21.22).

Conclusion: The incidence of HL in pregnancy appears to be higher than previously reported with no temporal trend over an 8-year period. Although there is a greater risk of preterm birth and maternal postpartum blood transfusion and VTE, overall maternal and neonatal major morbidity and mortality does not appear to be increased.

Keywords: Hodgkin; lymphoma; outcome; pregnancy
Corresponding author: Haim A. Abenhaim, MD, MPH, FRCSC, Department of Obstetrics and Gynecology, Jewish General Hospital, McGill University, Pavilion H, Rooms 325, 5790 Cote-des-Neiges Road, Montreal, Quebec, Canada H3S 1Y9, Tel.: 514-340-8222x5488, Fax: 514-340-7491, E-mail:

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The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2014-4-22
Accepted: 2014-7-22
Published Online: 2014-8-19
Published in Print: 2015-11-1

©2015 by De Gruyter

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Maternal risk: assessment and management
  4. Original articles – Obstetrics
  5. Ebola virus screening during pregnancy in West Africa: unintended consequences
  6. Strain at the internal cervical os assessed with quasi-static elastography is associated with the risk of spontaneous preterm delivery at ≤34 weeks of gestation
  7. Can routine laboratory parameters predict adverse pregnancy outcomes in intrahepatic cholestasis of pregnancy?
  8. Pulmonary edema in pregnancy and the puerperium: a cohort study of 53 cases
  9. Incidence and outcomes of women with Hodgkin’s lymphoma in pregnancy: a population-based study on 7.9 million births
  10. Differential utilization of expanded genetic screening tests in patients of reproductive ages from private and academic practices
  11. Association of maternal blood pressure in pregnancy with blood pressure of their offspring through adolescence
  12. Oxytocin utilization for labor induction in obese and lean women
  13. Breech delivery in the all fours position: a prospective observational comparative study with classic assistance
  14. Position at birth as an important factor for the occurrence of anal sphincter tears: a retrospective cohort study
  15. Emergency peripartum hysterectomy and risk factors by mode of delivery and obstetric history: a 10-year review from Helsinki University Central Hospital
  16. Delivery outcomes after day and night onset of labour
  17. Original articles – Fetus
  18. Perinatal outcome of congenital heart disease in a population with high consanguinity
  19. Complex and irregular heart rate dynamics in fetuses compromised by maternal anemia as a high-risk pregnancy
  20. Clinical application of fetal left modified myocardial performance index in the evaluation of fetal growth restriction
  21. First-trimester fetal growth discordance and development of preeclampsia in dichorionic twin pregnancies
  22. Original articles – Newborn
  23. Neonatal outcome in pregnant patients with antiphospholipid syndrome
  24. A longitudinal study of brainstem auditory response from birth to late term in late preterm babies and abnormal findings in high-risk babies
  25. Suctioning habits in the delivery room and the influence on postnatal adaptation – a video analysis
  26. Short communications
  27. Management of vasa previa during pregnancy
  28. Uterine rupture after the uterine fundal pressure maneuver
  29. Congress Calendar
  30. Congress Calendar
https://doi.org/10.1515/jpm-2014-0133
Schlagwörter für diesen Artikel
Hodgkin; lymphoma; outcome; pregnancy

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Maternal risk: assessment and management
  4. Original articles – Obstetrics
  5. Ebola virus screening during pregnancy in West Africa: unintended consequences
  6. Strain at the internal cervical os assessed with quasi-static elastography is associated with the risk of spontaneous preterm delivery at ≤34 weeks of gestation
  7. Can routine laboratory parameters predict adverse pregnancy outcomes in intrahepatic cholestasis of pregnancy?
  8. Pulmonary edema in pregnancy and the puerperium: a cohort study of 53 cases
  9. Incidence and outcomes of women with Hodgkin’s lymphoma in pregnancy: a population-based study on 7.9 million births
  10. Differential utilization of expanded genetic screening tests in patients of reproductive ages from private and academic practices
  11. Association of maternal blood pressure in pregnancy with blood pressure of their offspring through adolescence
  12. Oxytocin utilization for labor induction in obese and lean women
  13. Breech delivery in the all fours position: a prospective observational comparative study with classic assistance
  14. Position at birth as an important factor for the occurrence of anal sphincter tears: a retrospective cohort study
  15. Emergency peripartum hysterectomy and risk factors by mode of delivery and obstetric history: a 10-year review from Helsinki University Central Hospital
  16. Delivery outcomes after day and night onset of labour
  17. Original articles – Fetus
  18. Perinatal outcome of congenital heart disease in a population with high consanguinity
  19. Complex and irregular heart rate dynamics in fetuses compromised by maternal anemia as a high-risk pregnancy
  20. Clinical application of fetal left modified myocardial performance index in the evaluation of fetal growth restriction
  21. First-trimester fetal growth discordance and development of preeclampsia in dichorionic twin pregnancies
  22. Original articles – Newborn
  23. Neonatal outcome in pregnant patients with antiphospholipid syndrome
  24. A longitudinal study of brainstem auditory response from birth to late term in late preterm babies and abnormal findings in high-risk babies
  25. Suctioning habits in the delivery room and the influence on postnatal adaptation – a video analysis
  26. Short communications
  27. Management of vasa previa during pregnancy
  28. Uterine rupture after the uterine fundal pressure maneuver
  29. Congress Calendar
  30. Congress Calendar
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