Clinical application of fetal left modified myocardial performance index in the evaluation of fetal growth restriction
-
Ahmed Abobakr Nassr
, Alaaeldin Abdelhamid Youssef
, Mahmoud Sayed Zakherah , Alaa Mahmoud Ismail and Brian Charles Brost
Abstract
Objective: This study aims to evaluate cardiac function in fetuses with intrauterine growth restriction (IUGR) compared with healthy fetuses, using the left modified myocardial performance index (MPI) and the association between MPI and perinatal outcome.
Methods: Pregnant women between 34 and 39 weeks of gestation, who met the criteria for IUGR and were scheduled for delivery at an Egyptian tertiary medical center, were prospectively enrolled in the study. Women in the same gestational-age group with uncomplicated pregnancies were included as a control group. MPI was measured in all fetuses. The IUGR group was analyzed based on normal and abnormal umbilical artery (UA) Doppler. Perinatal outcomes were recorded.
Results: The mean left MPI was significantly higher in IUGR fetuses with abnormal UA Doppler (mean 0.58±SD 0.093) compared with healthy fetuses (mean 0.45±SD 0.070) (P<0.001). IUGR fetuses with abnormal left MPI showed significantly worse perinatal outcome and increased morbidity compared with the control group. IUGR fetuses with abnormal left MPI also showed significantly worse perinatal outcome compared with IUGR fetuses with normal MPI (whether the UA Doppler was normal or abnormal). The fetal MPI was associated with the severity of fetal compromise in IUGR fetuses based on the perinatal outcome.
Conclusion: MPI is a potentially useful tool in evaluating fetuses with suspected IUGR, which is crucial in classifying IUGR pregnancies into critical and non-critical cases and in predicting neonatal outcome.
References
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©2015 by De Gruyter
Articles in the same Issue
- Frontmatter
- Editorial
- Maternal risk: assessment and management
- Original articles – Obstetrics
- Ebola virus screening during pregnancy in West Africa: unintended consequences
- Strain at the internal cervical os assessed with quasi-static elastography is associated with the risk of spontaneous preterm delivery at ≤34 weeks of gestation
- Can routine laboratory parameters predict adverse pregnancy outcomes in intrahepatic cholestasis of pregnancy?
- Pulmonary edema in pregnancy and the puerperium: a cohort study of 53 cases
- Incidence and outcomes of women with Hodgkin’s lymphoma in pregnancy: a population-based study on 7.9 million births
- Differential utilization of expanded genetic screening tests in patients of reproductive ages from private and academic practices
- Association of maternal blood pressure in pregnancy with blood pressure of their offspring through adolescence
- Oxytocin utilization for labor induction in obese and lean women
- Breech delivery in the all fours position: a prospective observational comparative study with classic assistance
- Position at birth as an important factor for the occurrence of anal sphincter tears: a retrospective cohort study
- Emergency peripartum hysterectomy and risk factors by mode of delivery and obstetric history: a 10-year review from Helsinki University Central Hospital
- Delivery outcomes after day and night onset of labour
- Original articles – Fetus
- Perinatal outcome of congenital heart disease in a population with high consanguinity
- Complex and irregular heart rate dynamics in fetuses compromised by maternal anemia as a high-risk pregnancy
- Clinical application of fetal left modified myocardial performance index in the evaluation of fetal growth restriction
- First-trimester fetal growth discordance and development of preeclampsia in dichorionic twin pregnancies
- Original articles – Newborn
- Neonatal outcome in pregnant patients with antiphospholipid syndrome
- A longitudinal study of brainstem auditory response from birth to late term in late preterm babies and abnormal findings in high-risk babies
- Suctioning habits in the delivery room and the influence on postnatal adaptation – a video analysis
- Short communications
- Management of vasa previa during pregnancy
- Uterine rupture after the uterine fundal pressure maneuver
- Congress Calendar
- Congress Calendar
Articles in the same Issue
- Frontmatter
- Editorial
- Maternal risk: assessment and management
- Original articles – Obstetrics
- Ebola virus screening during pregnancy in West Africa: unintended consequences
- Strain at the internal cervical os assessed with quasi-static elastography is associated with the risk of spontaneous preterm delivery at ≤34 weeks of gestation
- Can routine laboratory parameters predict adverse pregnancy outcomes in intrahepatic cholestasis of pregnancy?
- Pulmonary edema in pregnancy and the puerperium: a cohort study of 53 cases
- Incidence and outcomes of women with Hodgkin’s lymphoma in pregnancy: a population-based study on 7.9 million births
- Differential utilization of expanded genetic screening tests in patients of reproductive ages from private and academic practices
- Association of maternal blood pressure in pregnancy with blood pressure of their offspring through adolescence
- Oxytocin utilization for labor induction in obese and lean women
- Breech delivery in the all fours position: a prospective observational comparative study with classic assistance
- Position at birth as an important factor for the occurrence of anal sphincter tears: a retrospective cohort study
- Emergency peripartum hysterectomy and risk factors by mode of delivery and obstetric history: a 10-year review from Helsinki University Central Hospital
- Delivery outcomes after day and night onset of labour
- Original articles – Fetus
- Perinatal outcome of congenital heart disease in a population with high consanguinity
- Complex and irregular heart rate dynamics in fetuses compromised by maternal anemia as a high-risk pregnancy
- Clinical application of fetal left modified myocardial performance index in the evaluation of fetal growth restriction
- First-trimester fetal growth discordance and development of preeclampsia in dichorionic twin pregnancies
- Original articles – Newborn
- Neonatal outcome in pregnant patients with antiphospholipid syndrome
- A longitudinal study of brainstem auditory response from birth to late term in late preterm babies and abnormal findings in high-risk babies
- Suctioning habits in the delivery room and the influence on postnatal adaptation – a video analysis
- Short communications
- Management of vasa previa during pregnancy
- Uterine rupture after the uterine fundal pressure maneuver
- Congress Calendar
- Congress Calendar