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Vitamin D deficiency and insulin resistance in obese African- American adolescents
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Gail Nunlee-Bland
Veröffentlicht/Copyright:
16. März 2011
Abstract
Objective: The study aim determined if low 25-hydroxy vitamin D levels correlated with low levels of adiponectin and insulin resistance in African American adolescents with body mass index ≥85th%.
Patients and methods: Fasting blood levels of adiponectin, 25-hydroxy vitamin D, insulin, glucose, lipid, leptin and glycosylated hemoglobin were measured in a total of 34 (19 study and 15 control) African American adolescents between the ages of 10 and 20 years. Nutritional vitamin D intake and body composition measurements were assessed. Insulin resistance was calculated using the homeostasis model assessment.
Results: Adiponectin, fasting insulin, glucose, leptin, triglycerides, HDL, and 25-hydroxy vitamin D levels all reached statistical significance in the group with body mass index ≥85th percentile when compared to the control population. There was no difference in vitamin D intake between the two groups.
Conclusions: Low vitamin D levels correlated with low adiponectin levels and obesity and insulin resistance.
Published Online: 2011-03-16
Published in Print: 2011-03-01
©2011 by Walter de Gruyter Berlin New York
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Schlagwörter für diesen Artikel
African-American;
adiponectin;
adolescents;
insulin resistance;
obesity;
vitamin D
Artikel in diesem Heft
- Publisher's Note
- Publisher's Note
- Editorial
- Sex steroid priming for growth hormone (GH) provocative tests: an endless debate with insufficient solution
- Not ready for prime time
- Commentary
- Sex hormone priming
- Pros of priming in the diagnosis of growth hormone deficiency
- Images in Pediatric Endokrinology
- Images in pediatric endocrinology: vitamin D deficiency rickets and other nutritional deficiencies in a 12-month-old infant
- Original Contributions
- The influence of an educational program on the HbA1c-level of adolescents with type 1 diabetes mellitus: a retrospective study
- Contribution of clinical, metabolic, and genetic factors on hypertension in obese children and adolescents
- Hyperphosphatemic tumoral calcinosis: a 10-year follow-up
- Vitamin D deficiency and insulin resistance in obese African- American adolescents
- Evaluation of children with nutritional rickets
- The effects of delivery route and anesthesia type on early postnatal weight loss in newborns: the role of vasoactive hormones
- Abdominal obesity is associated with cardiovascular risk in Japanese children and adolescents
- PPAR-γ2 Pro12Ala polymorphism is associated with post-challenge abnormalities of glucose homeostasis in children and adolescents with obesity
- The relationship between pubertal gynecomastia, prostate specific antigen, free androgen index, SHBG and sex steroids
- Severe hypercalcemia associated with Williams syndrome successfully treated with pamidronate infusion therapy
- The subtle signs of Wolfram (DIDMOAD) syndrome: not all juvenile diabetes is type 1 diabetes
- The frequency of Hashimoto thyroiditis in children and the relationship between urinary iodine level and Hashimoto thyroiditis
- The relationship between serum phosphate levels with childhood obesity and insulin resistance
- The relationship of salivary and cord blood cortisol inpreterm infants
- A comparison of referral patterns to the pediatric endocrine clinic before and after FDA approval of growth hormonefor idiopathic short stature
- Benign transient hyperphosphatasemia in infants and children: a prospective cohort
- Carotid arterial stiffness in overweight and obese Indian children
- Association study in Taiwanese girls with precocious puberty
- Patient Report Letters
- A homozygous recurring mutation in WISP3 causing progressive pseudorheumatoid arthropathy
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- Meetings Calendar
