Profile of mood states in adult type 1 diabetes mellitus men and women with disease onset in childhood and in adulthood
-
Lina Lašaitė
, Rytas Ostrauskas
Abstract
Introduction: Although diabetes may not be associated with psychopathology, it may be associated with less severe disturbances in psychosocial functioning. Emotional problems in relation to type 1 diabetes are usually analysed as symptoms of psychiatric conditions but not as states of mood. The aim was to compare profiles of mood states in adult patients with childhood-onset and adulthood-onset type 1 diabetes mellitus and to outline possible gender-specific differences.
Subjects and methods: A total of 214 adult type 1 diabetic patients were randomly selected from the Lithuanian Diabetes Registry. The mood states were compared in 105 (42 men and 63 women) patients with type 1 diabetes diagnosed during 0–18 years of life and in 109 (61 men and 48 women) diagnosed in adulthood. The scores of tension-anxiety, depression-dejection, anger-hostility, vigour-activity, fatigue-inertia and confusion-bewilderment were evaluated using the Profile of Mood States.
Results: Depression-dejection was higher in adulthood-onset diabetic women than in childhood-onset (p=0.005) diabetic patients. In childhood-onset diabetic patients depression-dejection (p=0.046) and confusion-bewilderment (p=0.033) were higher in women than in men. Adulthood-onset women with diabetes had higher tension-anxiety (p=0.027), depression-dejection (p=0.001), and confusion-bewilderment (p=0.004) scores than men. Multiple logistic analyses showed that adulthood-onset period of type 1 diabetes is associated with higher levels of depression-dejection [OR=1.1; 95% confidence intervals (CI) 1.01–1.19, p=0.025], longer diabetes duration (OR=2.00; 95% CI 1.27–2.03, p=0.012), higher HbA1c level (OR=1.15; 95% CI 1.02–1.3, p=0.023), and female gender (OR=2.51; 95% CI 1.29–2.90, p=0.021).
Conclusions: Profile of mood states in adult women with type 1 diabetes is worse than in men. Adulthood-onset type 1 diabetic women have higher depression-dejection than do childhood-onset diabetic patients. Adulthood-onset period of type 1 diabetes is associated with higher levels of depression-dejection, longer diabetes duration and female gender.
Acknowledgments
The study was financially supported by the Research Council of Lithuania, National Research Program of Noncommunicable Diseases, Contract number LIG-10019/LIG-06/2010.
Conflict of interest statement: Authors have no conflict of interest.
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©2015 by De Gruyter
Artikel in diesem Heft
- Frontmatter
- Highlight: Diabetes
- Diabetes mellitus in children and adolescents – a global epidemic which has become neglected
- Maturity-onset diabetes of the young (MODY): an update
- Relationship of plasma level of chemerin and vaspin to early atherosclerotic changes and cardiac autonomic neuropathy in adolescent type 1 diabetic patients
- How does autoimmune thyroiditis in children with type 1 diabetes mellitus influence glycemic control, lipid profile and thyroid volume?
- Profile of mood states in adult type 1 diabetes mellitus men and women with disease onset in childhood and in adulthood
- Evaluation of fetuin-A and carotid intima-media thickness in adolescent type 1 diabetic patients
- An increasing incidence of type 1 diabetes mellitus in Romanian children aged 0 to 17 years
- Resistin and right ventricular function in children with recently diagnosed type-1 diabetes mellitus: a case control study
- Assessment of human cartilage glycoprotein 39 (YKL-40), preptin, and nitric oxide in adolescent patients with type 1 diabetes and its relation to cardiorenal affection
- The effect of a home-based strength training program on type 2 diabetes risk in obese Latino boys
- From cerebral salt wasting to diabetes insipidus with adipsia: case report of a child with craniopharyngioma
- Three years of liraglutide treatment offers continuously optimal glycemic control in a pediatric patient with maturity-onset diabetes of the young type 3
- Diabetic euglycemic ketoacidosis in newly diagnosed type 1 diabetes mellitus during Ramadan fasting
- Transient neonatal hyperinsulinism with adaptation disorders: a report of three cases
- Acute mononeuropathy in a child with newly diagnosed type 1 diabetes mellitus
- Alternating hypoglycemia and hyperglycemia in a toddler with a homozygous p.R1419H ABCC8 mutation: an unusual clinical picture
- Cognitive functioning, metabolic control, and treatment type in youth with type 1 diabetes
- Images in pediatric endocrinology
- Benefit of testosterone in pediatric genital trauma
- Original articles
- Attenuated salivary cortisol response after exercise test in children with asthma
- Reliability of pubertal maturation self-assessment in a school-based survey
- Detection of inborn errors of metabolism using GC-MS: over 3 years of experience in southern China
- Assessing biological maturity: chronological age and the pubertal development scale predict free testosterone in adolescent males
- Evaluation of puberty by verifying spontaneous and stimulated gonadotropin values in girls
- Longitudinal changes in C-reactive protein, proform of eosinophil major basic protein, and pregnancy-associated plasma protein-A during weight changes in obese children
- Caries in adolescents in relation to their skeletal status
- Endothelial and metabolic disorders in adolescence: low birth weight is not an isolated risk factor
- Comparison of cortisol samples in the first two weeks of life in preterm infants
- Mutations in BTD gene causing biotinidase deficiency: a regional report
- Patient reports
- Late-onset hypercalcemia in Williams-Beuren syndrome: importance of early and frequent screening and intervention
- Hepatoblastoma presenting as precocious puberty: a case report
- Three cases of Wolfram syndrome with different clinical aspects
- L-asparaginase induced hypoglycemia in a case of acute lymphoblastic leukemia: a patient report
- Pyogenic granuloma, an unusual presentation of peripubertal vaginal bleeding. Case report and review of the literature
- Octreotide-associated cholestasis and hepatitis in an infant with congenital hyperinsulinism
- Two novel mutations in the homogentisate-1,2-dioxygenase gene identified in Chinese Han Child with Alkaptonuria
- Pituitary abscess in an adolescent girl: a case report and review of the literature
- Neonatal thyrotoxicosis with severe supraventricular tachycardia: case report and review of the literature
- Consumptive hypothyroidism associated with parotid infantile hemangioma
- Novel mutations in the SLC25A13 gene in a patient with NICCD and severe manifestations
- Short communications
- Tetrahydrobiopterin deficiency among Serbian patients presenting with hyperphenylalaninemia
Artikel in diesem Heft
- Frontmatter
- Highlight: Diabetes
- Diabetes mellitus in children and adolescents – a global epidemic which has become neglected
- Maturity-onset diabetes of the young (MODY): an update
- Relationship of plasma level of chemerin and vaspin to early atherosclerotic changes and cardiac autonomic neuropathy in adolescent type 1 diabetic patients
- How does autoimmune thyroiditis in children with type 1 diabetes mellitus influence glycemic control, lipid profile and thyroid volume?
- Profile of mood states in adult type 1 diabetes mellitus men and women with disease onset in childhood and in adulthood
- Evaluation of fetuin-A and carotid intima-media thickness in adolescent type 1 diabetic patients
- An increasing incidence of type 1 diabetes mellitus in Romanian children aged 0 to 17 years
- Resistin and right ventricular function in children with recently diagnosed type-1 diabetes mellitus: a case control study
- Assessment of human cartilage glycoprotein 39 (YKL-40), preptin, and nitric oxide in adolescent patients with type 1 diabetes and its relation to cardiorenal affection
- The effect of a home-based strength training program on type 2 diabetes risk in obese Latino boys
- From cerebral salt wasting to diabetes insipidus with adipsia: case report of a child with craniopharyngioma
- Three years of liraglutide treatment offers continuously optimal glycemic control in a pediatric patient with maturity-onset diabetes of the young type 3
- Diabetic euglycemic ketoacidosis in newly diagnosed type 1 diabetes mellitus during Ramadan fasting
- Transient neonatal hyperinsulinism with adaptation disorders: a report of three cases
- Acute mononeuropathy in a child with newly diagnosed type 1 diabetes mellitus
- Alternating hypoglycemia and hyperglycemia in a toddler with a homozygous p.R1419H ABCC8 mutation: an unusual clinical picture
- Cognitive functioning, metabolic control, and treatment type in youth with type 1 diabetes
- Images in pediatric endocrinology
- Benefit of testosterone in pediatric genital trauma
- Original articles
- Attenuated salivary cortisol response after exercise test in children with asthma
- Reliability of pubertal maturation self-assessment in a school-based survey
- Detection of inborn errors of metabolism using GC-MS: over 3 years of experience in southern China
- Assessing biological maturity: chronological age and the pubertal development scale predict free testosterone in adolescent males
- Evaluation of puberty by verifying spontaneous and stimulated gonadotropin values in girls
- Longitudinal changes in C-reactive protein, proform of eosinophil major basic protein, and pregnancy-associated plasma protein-A during weight changes in obese children
- Caries in adolescents in relation to their skeletal status
- Endothelial and metabolic disorders in adolescence: low birth weight is not an isolated risk factor
- Comparison of cortisol samples in the first two weeks of life in preterm infants
- Mutations in BTD gene causing biotinidase deficiency: a regional report
- Patient reports
- Late-onset hypercalcemia in Williams-Beuren syndrome: importance of early and frequent screening and intervention
- Hepatoblastoma presenting as precocious puberty: a case report
- Three cases of Wolfram syndrome with different clinical aspects
- L-asparaginase induced hypoglycemia in a case of acute lymphoblastic leukemia: a patient report
- Pyogenic granuloma, an unusual presentation of peripubertal vaginal bleeding. Case report and review of the literature
- Octreotide-associated cholestasis and hepatitis in an infant with congenital hyperinsulinism
- Two novel mutations in the homogentisate-1,2-dioxygenase gene identified in Chinese Han Child with Alkaptonuria
- Pituitary abscess in an adolescent girl: a case report and review of the literature
- Neonatal thyrotoxicosis with severe supraventricular tachycardia: case report and review of the literature
- Consumptive hypothyroidism associated with parotid infantile hemangioma
- Novel mutations in the SLC25A13 gene in a patient with NICCD and severe manifestations
- Short communications
- Tetrahydrobiopterin deficiency among Serbian patients presenting with hyperphenylalaninemia