Cognitive functioning, metabolic control, and treatment type in youth with type 1 diabetes
-
Christine A. Limbers
,
Kara Emery
Abstract
Background: There is growing evidence that cognitive functioning plays an important role in self-care behavior and glycemic control in pediatric patients with type 1 diabetes. The aim of this pilot study was to examine whether there were differences in glycemic control and cognitive functioning between youth with T1D treated with continuous subcutaneous insulin infusion and multiple daily injections.
Methods: The sample consisted of 29 youth diagnosed with type 1 diabetes ages 6–15 years (mean age=11.72 years) receiving care at an outpatient pediatric endocrinology clinic. Youth were administered the Wechsler Abbreviated Scale of Intelligence and Wide Range Assessment of Memory and Learning. Independent samples t-tests were used to compare youth with T1D treated with MDI vs. CSII on glycemic control, verbal memory, visual memory, attention/concentration, and intelligence.
Results: Mean intelligence scores for the insulin pump sample were higher than the daily injection sample. This difference was a medium to large effect. After controlling for demographic variables, age of onset for diabetes, and glycemic control, treatment type was still a significant predictor of intelligence demonstrating that CSII was associated with higher intelligence scores.
Conclusion: The use of standardized measures of cognitive functioning in routine clinical care may shed some light on the complex interplay between cognitive functioning, treatment type, and glycemic control when managing pediatric patients with T1D.
References
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2. Soutour SA, Chen R, Streisand R, Kaplowitz P, Holmes CS. Memory matters: developmental differences in predictors of diabetes care behaviors. J Pediatr Psychol 2004;29:493–505.10.1093/jpepsy/jsh052Search in Google Scholar PubMed
3. Slijper F, De Beaufort CE, Bruining GJ, De Visser JJ, Aarsen RS, et al. Psychological impact of continuous subcutaneous insulin infusion pump therapy in non-selected newly diagnosed insulin dependent type 1 diabetic children: evaluation after two years of therapy. Diabetes Metab 1990;16:273–7.Search in Google Scholar
4. Knight S, Northam E, Donath S, Gardner A, Harkin N, et al. Improvements in cognition, mood and behaviour following commencement of continuous subcutaneous insulin infusion therapy in children with type 1 diabetes mellitus: a pilot study. Diabetologia 2009;52:193–8.10.1007/s00125-008-1197-3Search in Google Scholar PubMed
©2015 by De Gruyter
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Articles in the same Issue
- Frontmatter
- Highlight: Diabetes
- Diabetes mellitus in children and adolescents – a global epidemic which has become neglected
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- Relationship of plasma level of chemerin and vaspin to early atherosclerotic changes and cardiac autonomic neuropathy in adolescent type 1 diabetic patients
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