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The effect of a home-based strength training program on type 2 diabetes risk in obese Latino boys

  • Louise A. Kelly EMAIL logo , Armando Loza , Xiao Lin , E. Todd Schroeder , Adrienne Hughes , Alison Kirk and Ann-Maire Knowles
Published/Copyright: March 7, 2015
Journal of Pediatric Endocrinology and Metabolism
From the journal Journal of Pediatric Endocrinology and Metabolism Volume 28 Issue 3-4

Abstract

Objective: To determine the effects of a home-based strength training (HBST) intervention on insulin sensitivity (SI), compensatory acute insulin response and β-cell function, body composition measures, and maximum strength in obese Latino boys.

Methods: A total of 26 obese Latino males aged between 14 and 18 years were randomized to either a twice-weekly (n=15) or a control group (C; n=15) for 16 weeks. HBST for 16 weeks, composed of two 1-h sessions per week. Outcome measures were assessed pre-and post-intervention/control condition and included SI, acute insulin response to glucose (AIR) and disposition index (DI), fasting glucose, 2-h glucose, body composition using waist-hip circumferences, body mass index (BMI), dual energy X-ray absorptiometry (DEXA) scan, blood pressure, and strength by 1-repetition maximum. A repeated measures GLM was used to assess differences in changes in outcome measures, between the C and the HBST groups.

Results: There were no significant overall intervention effects on any of the outcome variables (p<0.05).

Conclusion: These results suggest that an HBST does not improve SI, maximal strength or decrease adiposity in obese Latino boys.

Keywords: exercise; insulin resistance; insulin sensitivity (SI); Latino; pediatric; strength training
Corresponding author: Louise A. Kelly, PhD, Department of Exercise Science, California Lutheran University, 60 W. Olsen Road, #3400, Thousand Oaks, CA 93065, USA, Phone: +1-805-493-3547, Fax: +1-805-493-3860, E-mail:
aKelly was responsible for study concept and design, statistical analysis, and obtaining funding.bKelly, Loza, and Lin were responsible for data acquisition.cKelly and Schroeder were analysis and interpretation of data and they provided study supervision.dKelly, Loza, Lin, Schroeder, Kirk, Hughes and Knowles were responsible for drafting the manuscript and for the critical revision of the manuscript for important intellectual content.All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.

Acknowledgments

This work was supported by the National Institute of Cancer (NCI), University of Southern California Transdisciplinary Research on Energetics and Cancer (U54 CA 116848). The authors are grateful to the nurses and nutrition staff at the USC-GCRC. Finally, they express their gratitude to the children and their families for making this study possible.

Conflict of interest statement: The authors have no conflicts of interest relevant to this article to disclose.

Research funding: National Institute of Cancer (NCI), University of Southern California Transdisciplinary Research on Energetics and Cancer (U54 CA 116848).

Financial disclosers: The authors have no financial relationships relevant to this article to disclose.

Clinical trial registration number: NCT01441323

Ethics: The Institutional Review Board of the University of Southern California approved this study, and all procedures were performed in accordance with standards outlined in the Helsinki Declaration.

Data sharing: There is no additional data available.

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Received: 2014-11-13
Accepted: 2015-1-23
Published Online: 2015-3-7
Published in Print: 2015-3-1

©2015 by De Gruyter

Articles in the same Issue

  1. Frontmatter
  2. Highlight: Diabetes
  3. Diabetes mellitus in children and adolescents – a global epidemic which has become neglected
  4. Maturity-onset diabetes of the young (MODY): an update
  5. Relationship of plasma level of chemerin and vaspin to early atherosclerotic changes and cardiac autonomic neuropathy in adolescent type 1 diabetic patients
  6. How does autoimmune thyroiditis in children with type 1 diabetes mellitus influence glycemic control, lipid profile and thyroid volume?
  7. Profile of mood states in adult type 1 diabetes mellitus men and women with disease onset in childhood and in adulthood
  8. Evaluation of fetuin-A and carotid intima-media thickness in adolescent type 1 diabetic patients
  9. An increasing incidence of type 1 diabetes mellitus in Romanian children aged 0 to 17 years
  10. Resistin and right ventricular function in children with recently diagnosed type-1 diabetes mellitus: a case control study
  11. Assessment of human cartilage glycoprotein 39 (YKL-40), preptin, and nitric oxide in adolescent patients with type 1 diabetes and its relation to cardiorenal affection
  12. The effect of a home-based strength training program on type 2 diabetes risk in obese Latino boys
  13. From cerebral salt wasting to diabetes insipidus with adipsia: case report of a child with craniopharyngioma
  14. Three years of liraglutide treatment offers continuously optimal glycemic control in a pediatric patient with maturity-onset diabetes of the young type 3
  15. Diabetic euglycemic ketoacidosis in newly diagnosed type 1 diabetes mellitus during Ramadan fasting
  16. Transient neonatal hyperinsulinism with adaptation disorders: a report of three cases
  17. Acute mononeuropathy in a child with newly diagnosed type 1 diabetes mellitus
  18. Alternating hypoglycemia and hyperglycemia in a toddler with a homozygous p.R1419H ABCC8 mutation: an unusual clinical picture
  19. Cognitive functioning, metabolic control, and treatment type in youth with type 1 diabetes
  20. Images in pediatric endocrinology
  21. Benefit of testosterone in pediatric genital trauma
  22. Original articles
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  24. Reliability of pubertal maturation self-assessment in a school-based survey
  25. Detection of inborn errors of metabolism using GC-MS: over 3 years of experience in southern China
  26. Assessing biological maturity: chronological age and the pubertal development scale predict free testosterone in adolescent males
  27. Evaluation of puberty by verifying spontaneous and stimulated gonadotropin values in girls
  28. Longitudinal changes in C-reactive protein, proform of eosinophil major basic protein, and pregnancy-associated plasma protein-A during weight changes in obese children
  29. Caries in adolescents in relation to their skeletal status
  30. Endothelial and metabolic disorders in adolescence: low birth weight is not an isolated risk factor
  31. Comparison of cortisol samples in the first two weeks of life in preterm infants
  32. Mutations in BTD gene causing biotinidase deficiency: a regional report
  33. Patient reports
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  35. Hepatoblastoma presenting as precocious puberty: a case report
  36. Three cases of Wolfram syndrome with different clinical aspects
  37. L-asparaginase induced hypoglycemia in a case of acute lymphoblastic leukemia: a patient report
  38. Pyogenic granuloma, an unusual presentation of peripubertal vaginal bleeding. Case report and review of the literature
  39. Octreotide-associated cholestasis and hepatitis in an infant with congenital hyperinsulinism
  40. Two novel mutations in the homogentisate-1,2-dioxygenase gene identified in Chinese Han Child with Alkaptonuria
  41. Pituitary abscess in an adolescent girl: a case report and review of the literature
  42. Neonatal thyrotoxicosis with severe supraventricular tachycardia: case report and review of the literature
  43. Consumptive hypothyroidism associated with parotid infantile hemangioma
  44. Novel mutations in the SLC25A13 gene in a patient with NICCD and severe manifestations
  45. Short communications
  46. Tetrahydrobiopterin deficiency among Serbian patients presenting with hyperphenylalaninemia
https://doi.org/10.1515/jpem-2014-0470
Keywords for this article
exercise; insulin resistance; insulin sensitivity (SI); Latino; pediatric; strength training

Articles in the same Issue

  1. Frontmatter
  2. Highlight: Diabetes
  3. Diabetes mellitus in children and adolescents – a global epidemic which has become neglected
  4. Maturity-onset diabetes of the young (MODY): an update
  5. Relationship of plasma level of chemerin and vaspin to early atherosclerotic changes and cardiac autonomic neuropathy in adolescent type 1 diabetic patients
  6. How does autoimmune thyroiditis in children with type 1 diabetes mellitus influence glycemic control, lipid profile and thyroid volume?
  7. Profile of mood states in adult type 1 diabetes mellitus men and women with disease onset in childhood and in adulthood
  8. Evaluation of fetuin-A and carotid intima-media thickness in adolescent type 1 diabetic patients
  9. An increasing incidence of type 1 diabetes mellitus in Romanian children aged 0 to 17 years
  10. Resistin and right ventricular function in children with recently diagnosed type-1 diabetes mellitus: a case control study
  11. Assessment of human cartilage glycoprotein 39 (YKL-40), preptin, and nitric oxide in adolescent patients with type 1 diabetes and its relation to cardiorenal affection
  12. The effect of a home-based strength training program on type 2 diabetes risk in obese Latino boys
  13. From cerebral salt wasting to diabetes insipidus with adipsia: case report of a child with craniopharyngioma
  14. Three years of liraglutide treatment offers continuously optimal glycemic control in a pediatric patient with maturity-onset diabetes of the young type 3
  15. Diabetic euglycemic ketoacidosis in newly diagnosed type 1 diabetes mellitus during Ramadan fasting
  16. Transient neonatal hyperinsulinism with adaptation disorders: a report of three cases
  17. Acute mononeuropathy in a child with newly diagnosed type 1 diabetes mellitus
  18. Alternating hypoglycemia and hyperglycemia in a toddler with a homozygous p.R1419H ABCC8 mutation: an unusual clinical picture
  19. Cognitive functioning, metabolic control, and treatment type in youth with type 1 diabetes
  20. Images in pediatric endocrinology
  21. Benefit of testosterone in pediatric genital trauma
  22. Original articles
  23. Attenuated salivary cortisol response after exercise test in children with asthma
  24. Reliability of pubertal maturation self-assessment in a school-based survey
  25. Detection of inborn errors of metabolism using GC-MS: over 3 years of experience in southern China
  26. Assessing biological maturity: chronological age and the pubertal development scale predict free testosterone in adolescent males
  27. Evaluation of puberty by verifying spontaneous and stimulated gonadotropin values in girls
  28. Longitudinal changes in C-reactive protein, proform of eosinophil major basic protein, and pregnancy-associated plasma protein-A during weight changes in obese children
  29. Caries in adolescents in relation to their skeletal status
  30. Endothelial and metabolic disorders in adolescence: low birth weight is not an isolated risk factor
  31. Comparison of cortisol samples in the first two weeks of life in preterm infants
  32. Mutations in BTD gene causing biotinidase deficiency: a regional report
  33. Patient reports
  34. Late-onset hypercalcemia in Williams-Beuren syndrome: importance of early and frequent screening and intervention
  35. Hepatoblastoma presenting as precocious puberty: a case report
  36. Three cases of Wolfram syndrome with different clinical aspects
  37. L-asparaginase induced hypoglycemia in a case of acute lymphoblastic leukemia: a patient report
  38. Pyogenic granuloma, an unusual presentation of peripubertal vaginal bleeding. Case report and review of the literature
  39. Octreotide-associated cholestasis and hepatitis in an infant with congenital hyperinsulinism
  40. Two novel mutations in the homogentisate-1,2-dioxygenase gene identified in Chinese Han Child with Alkaptonuria
  41. Pituitary abscess in an adolescent girl: a case report and review of the literature
  42. Neonatal thyrotoxicosis with severe supraventricular tachycardia: case report and review of the literature
  43. Consumptive hypothyroidism associated with parotid infantile hemangioma
  44. Novel mutations in the SLC25A13 gene in a patient with NICCD and severe manifestations
  45. Short communications
  46. Tetrahydrobiopterin deficiency among Serbian patients presenting with hyperphenylalaninemia
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