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Peptide YY in children: a review
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Janet M. Wojcicki
Veröffentlicht/Copyright:
15. März 2012
Abstract
Background: Peptide YY has been found to reduce food intake via the vagal-brainstem-hypothalamic pathway. There is some indication that PYY levels may differ in early childhood in comparison with adult studies. Studies of PYY in children have yet to be synthesized.
Methods: This review synthesized 21 articles including studies with infants/newborns, primary school age children and populations with special health needs.
Results: Some important differences emerge between studies of PYY in children in comparison to those with adults. In those studies with infants and newborns, there is a high level of PYY in preterm and full term neonates in comparison with school age children and adults. As children get older the relationship between PYY levels and body composition and obesity is more similar to that of adults. Fasting PYY levels may be lower in obese children in comparison with adults and weight loss may restore a higher postprandial level of PYY in contrast with adults whose levels remain low.
Conclusions: Additional studies are needed to better understand the role of higher PYY in infancy and to assess the effectiveness of different diets on children throughout time-points in growth and development as well as those with different racial/ethnic background.
Received: 2011-12-16
Accepted: 2012-1-13
Published Online: 2012-03-15
Published in Print: 2012-04-01
©2012 by Walter de Gruyter Berlin Boston
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Artikel in diesem Heft
- Review Articles
- Peptide YY in children: a review
- Brown adipose tissue: distribution and influencing factors on FDG PET/CT scan
- Mini Review
- Approach to the management of slipped capital femoral epiphysis and primary hyperparathyroidism
- Original Articles
- Current normal values for TSH and FT3 in children are too low: evidence from over 11,000 samples
- Elevated serum ferritin and soluble transferrin receptor in infants with congenital hypothyroidism
- Implications of gastrointestinal hormones in the pathogenesis of obesity in prepubertal children
- Oxidative stress in obese children and its relation with insulin resistance
- Final height in elite male artistic gymnasts
- Expression of SOCS1, SOCS2, and SOCS3 in growth hormone-stimulated skin fibroblasts from children with idiopathic short stature
- Evaluation of skeletal maturity score for Korean children and the standard for comparison of bone age and chronological age in normal children
- Children and adolescent acceptability of a new device system to administer human growth hormone – a pilot study
- The analysis of clinical manifestations and genetic mutations in Chinese boys with primary adrenal insufficiency
- Replication of clinical associations with 17-hydroxyprogesterone in preterm newborns
- Prevention of bone loss in children receiving long-term glucocorticoids with calcium and alfacalcidol or menatetrenone
- Evaluation of serum kisspeptin levels in girls in the diagnosis of central precocious puberty and in the assessment of pubertal suppression
- Hypophosphatemia in small for gestational age extremely low birth weight infants receiving parenteral nutrition in the first week after birth
- Patient Reports
- Partial benefit of anastrozole in the long-term treatment of precocious puberty in McCune-Albright syndrome
- Palmoplantar keratoderma with growth hormone deficiency
- Propylthiouracil hepatitis: report of a case and extensive review of the literature
- Autonomous functioning thyroid nodule successfully treated with radioiodine in a 3 and a half-year-old boy
- Hashimoto thyroiditis associated with ataxia telangiectasia
- Improved long-term glucose control in neonatal diabetes mellitus after early sulfonylurea allergy
- Stroke in a child with Adams-Oliver syndrome and mixed diabetic ketoacidosis and hyperglycemic hyperosmolar syndrome
- A novel mutation of the insulin receptor gene in a preterm infant with Donohue syndrome and heart failure
- Permanent neonatal diabetes mellitus due to KCNJ11 mutation in a Portuguese family: transition from insulin to oral sulfonylureas
- Successful prospective management of neonatal citrullinemia
- A Chinese patient with acquired partial lipodystrophy caused by a novel mutation with LMNB2 gene
- Warburg Micro syndrome
- Inguinal ovary as a rare diagnostic sign of Mayer-Rokitansky-Küster-Hauser syndrome
- Letters to the Editor
- Endocrine disruptors and fulminant type 1 diabetes: is there a link?
- The appropriate use of sensitive tests of hypothalamic-pituitary-adrenal-axis suppression
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