Abstract
Objectives
Recurrence rate of nasal polyps is high following endoscopic sinus surgery. To improve the surgical outcome, steroid impregnated nasal dressing is used postoperatively We aimed to compare the effect of Tualang honey impregnated nasal dressing with steroid impregnated nasal dressing on wound healing and surgical outcomes in post endoscopic sinus surgery patients.
Methods
A prospective, randomized, controlled trial was carried out at two tertiary hospitals. 32 patients diagnosed with chronic rhinosinusitis and had underwent endoscopic sinus surgery were enrolled. The study group received 2 mL of Tualang honey nasal dressing and the control group received nasal dressing with 2 mL of triamcinolone 20 mg/mL as positive control. A 2 cm nasal dressing was placed longitudinally into the middle meatuses of both nasal cavities. Postoperative healing assessments of edema, crusting, secretions, scarring and symptoms were performed at postoperative day 7, 14, 28 and at 3 months using Sinonasal Outcome Test 22 questionnaire and modified Lund-Kennedy scoring system.
Results
There were no significant differences noted in the scores of Sinonasal Outcome Test 22 and modified Lund-Kennedy at Day 7, 14 and 28 (p>0.05) for both groups. At 3rd month, patients in the triamcinolone group had lesser symptoms and better endoscopic findings (p<0.05).
Conclusion
Tualang honey is not as effective as steroid in achieving good wound healing and surgical outcomes in post endoscopic sinus surgery patients. Thus, it is not suitable as a substitute for steroid to reduce symptoms and prevent recurrence of disease.
Research funding: None declared.
Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.
Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.
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© 2020 Walter de Gruyter GmbH, Berlin/Boston
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- The potentiation of beta-lactam and anti-bacterial activities of lipophilic constituents from Mesua ferrae leaves against methicillin-resistant Staphylococcus aureus
- Influence of irisin on diet-induced metabolic syndrome in experimental rat model
- Modulatory effect of methanol extract of Annona muricata stem bark on mitochondrial membrane permeability transition pore in normal rat liver and monosodium glutamate-induced uterine hyperplasia
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- Functional status in adhesive capsulitis – yoga vs. physiotherapy: a quasi experimental study
- Okada Purifying Therapy in combination with duloxetine vs. duloxetine alone in patients with TMD and fibromyalgia: a randomized clinical study
- The FIFA 11+ does not alter performance in amateur female basketball players—a randomized control trial
- Body composition, phenotype and central obesity indices in Egyptian women with non-alcoholic fatty liver disease
- Immediate effect of interscapular cupping on blood pressure, oxygen saturation, pulse rate and chest expansion in sedentary smoker students
- The effects of an olive-oil massage on hemodialysis patients suffering from fatigue at a hemodialysis unit in southern India – a randomized controlled trial
- Effects of epigallocatechin-3-gallate of Camellia sinensis leaves on blood pressure, lipid profile, atherogenic index of plasma and some inflammatory and antioxidant markers in type 2 diabetes mellitus patients: a clinical trial
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Articles in the same Issue
- Frontmatter
- Reviews
- The effect of Nigella sativa on oxidative stress and inflammatory biomarkers: a systematic review and meta-analysis
- Effect of fennel on primary dysmenorrhea: a systematic review and meta-analysis
- Raising burden of non-communicable diseases: importance of integrating Yoga and Naturopathy at primary care level
- Research Articles Basic
- Marketing and legal status of phytomedicines and food supplements in Morocco
- Hydrogen sulfide as a mediator of endothelium-dependent relaxation evoked by Moringa oleifera leaf extract in mesenteric arterial beds isolated from L-NAME hypertensive rats
- Acute and sub-acute toxicity assessment of aqueous leaves extract of Crassocephalum crepidioides (Asteraceae) in Wistar rats
- Zingerone improves the immune responses in an animal model of breast cancer
- Evaluation of efficacy of Bombax ceiba extract and its major constituent, mangiferin in streptozotocin (STZ)-induced diabetic rats
- Bacterial endosymbiont inhabiting Leucaena leucocephala leaves and their antioxidant and antidiabetic potential
- Ameliorative effect of morin on dutasteride-tamsulosin-induced testicular oxidative stress in rat
- The potentiation of beta-lactam and anti-bacterial activities of lipophilic constituents from Mesua ferrae leaves against methicillin-resistant Staphylococcus aureus
- Influence of irisin on diet-induced metabolic syndrome in experimental rat model
- Modulatory effect of methanol extract of Annona muricata stem bark on mitochondrial membrane permeability transition pore in normal rat liver and monosodium glutamate-induced uterine hyperplasia
- Research Articles Clinical
- Functional status in adhesive capsulitis – yoga vs. physiotherapy: a quasi experimental study
- Okada Purifying Therapy in combination with duloxetine vs. duloxetine alone in patients with TMD and fibromyalgia: a randomized clinical study
- The FIFA 11+ does not alter performance in amateur female basketball players—a randomized control trial
- Body composition, phenotype and central obesity indices in Egyptian women with non-alcoholic fatty liver disease
- Immediate effect of interscapular cupping on blood pressure, oxygen saturation, pulse rate and chest expansion in sedentary smoker students
- The effects of an olive-oil massage on hemodialysis patients suffering from fatigue at a hemodialysis unit in southern India – a randomized controlled trial
- Effects of epigallocatechin-3-gallate of Camellia sinensis leaves on blood pressure, lipid profile, atherogenic index of plasma and some inflammatory and antioxidant markers in type 2 diabetes mellitus patients: a clinical trial
- The effect of practicing yoga during pregnancy on labor stages length, anxiety and pain: a randomized controlled trial
- Effect of lumbar stabilization exercises and thoracic mobilization with strengthening exercises on pain level, thoracic kyphosis, and functional disability in chronic low back pain
- A prospective controlled study on Ramadan fasting in the healthy young males in summer in Germany: effect on cytokines
- Tualang honey versus steroid impregnated nasal dressing following endoscopic sinus surgery: a randomized controlled trial
- Short Communications
- Improved anti-arthritic activity of ginger extract, a traditional medicine, using novel drug delivery approach
- Efficacy of fenugreek seed extract on men's psychological and physical health: a randomized placebo-controlled double-blind clinical trial