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Greater effects of high- compared with moderate-intensity interval training on thyroid hormones in overweight/obese adolescent girls

  • Wissal Abassi EMAIL logo , Nejmeddine Ouerghi ORCID logo , Hatem Ghouili , Salma Haouami and Anissa Bouassida EMAIL logo
Published/Copyright: November 25, 2020
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Hormone Molecular Biology and Clinical Investigation
From the journal Hormone Molecular Biology and Clinical Investigation Volume 41 Issue 4

Abstract

Objectives

To investigate the effects of 12-week high-intensity- (HIIT) vs. moderate-intensity-interval training (MIIT) on thyroid stimulating hormone (TSH) and thyroxine (T4) and insulin-resistance in overweight/obese adolescent girls.

Methods

Twenty four adolescent girls (age 16.5±1.36 yrs) were randomly allocated into three groups: (1) HIIT (2 blocks per session of 6–8 bouts of 30 s runs at 100–110% maximal aerobic speed (MAS), with 30 s active recovery between bouts at 50% MAS; n=8), (2) MIIT (2 blocks per session of 6–8 bouts of 30 s runs at 70–80% MAS, with 30 s active recovery between bouts at 50% MAS; n=8) and (3) control group (no exercise, n=8). Each training groups engaged in three sessions per week during three months. Anthropometric parameters, aerobic capacity, homeostasis model assessment index for insulin resistance (HOMA-IR) as well as plasma TSH and T4 levels were assessed in all subjects before- and after-training.

Results

Following both training programs, body mass, body mass index Z-score, waist circumference and body fat decreased, while aerobic capacity increased. However, TSH and T4 concentrations decreased only after the HIIT (−30.47%, p<0.05, ES=1.42 and −12.86%, p<0.05, ES=1.18; respectively). The HOMA-IR decreased in both training groups (−26.25%, p<0.05, ES=1.87 for MIIT and −21.72%, p<0.05, ES=2.14 for HIIT).

Conclusion

Twelve weeks of HIIT was effective in reducing circulating TSH and T4 levels, unlike MIIT, in overweight/obese adolescent girls. These findings indicated that the stimulation of pituitary-thyroid function is more sensitive to training intensity than training duration. Further studies are needed to confirm this conclusion.

Keywords: intermittent training; insulin-resistance; thyroid stimulating hormone; thyroxine; training intensity
Corresponding author: Wissal Abass, Research Unit, Sportive Performance and Physical Rehabilitation, High Institute of Sports and Physical Education of Kef, University of Jendouba, Kef, Tunisia; and Higher Institute of Sport and Physical Education of Ksar Said, University of “La Manouba”, Manouba, Tunisia, E-mail: ; and Anissa Bouassida, Research Unit, Sportive Performance and Physical Rehabilitation, High Institute of Sports and Physical Education of Kef, University of Jendouba, Kef, Tunisia, E-mail:

Acknowledgement

The authors thank the participants for their voluntary participation in the study.

  1. Research funding: All authors state no funding was involved.

  2. Author contributions: All authors have made substantial contributions to various elements of the study.

  3. Competing interests: All authors declare no conflicts of interest.

  4. Informed consent: All participant and their parents signed informed consent forms.

  5. Ethical approval: The research was conducted in accordance to the Declaration of Helsinki and was fully approved by the Scientific and Ethics Committee of High Institute of Sports and Physical Education of Kef (UR13JS01).

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Received: 2020-05-23
Accepted: 2020-10-26
Published Online: 2020-11-25

© 2020 Walter de Gruyter GmbH, Berlin/Boston

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https://doi.org/10.1515/hmbci-2020-0031
Keywords for this article
intermittent training; insulin-resistance; thyroid stimulating hormone; thyroxine; training intensity

Articles in the same Issue

  1. Letter to the Editor
  2. Evidence-based medicine is a valuable tool for a successful decision-making on risk-reducing bilateral mastectomy
  3. Original Articles
  4. Melatonin inhibits high glucose-induced ox-LDL/LDL expression and apoptosis in human umbilical endothelial cells
  5. Effects of metformin and insulin therapy regimens on postpartum oral glucose tolerance test results in pregnant women with gestational diabetes mellitus: a comparative study
  6. Association of IL-33 gene rs16924159 polymorphism and recurrent pregnancy loss in Iranian Azeri women
  7. Greater effects of high- compared with moderate-intensity interval training on thyroid hormones in overweight/obese adolescent girls
  8. Effect of Artemisia absinthium ethanolic extract on oxidative stress markers and the TLR4, S100A4, Bax and Bcl-2 genes expression in the kidney of STZ-induced diabetic rats
  9. Associations of endothelial biomarkers, nitric oxide metabolites and endothelin, with blood pressure and coronary lesions depend on cardiovascular risk and sex to mark endothelial dysfunction on the SCORE scale
  10. Association of nitric oxide synthase 3 gene rs1799983 G/T polymorphism with idiopathic asthenozoospermia in Iranian Azeri males: a case-control study
  11. Adiponectin and leptin levels in normal weight women with polycystic ovary syndrome
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  17. Breast cancer risk factors in Iran: a systematic review & meta-analysis
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