Startseite Lebenswissenschaften Avobenzone encapsulated in modified dextrin for improved UV protection and reduced skin penetration
Artikel
Lizenziert
Nicht lizenziert Erfordert eine Authentifizierung

Avobenzone encapsulated in modified dextrin for improved UV protection and reduced skin penetration

  • Chia-Ching Li EMAIL logo , Li-Huei Lin , Hsun-Tsing Lee und Jing-Ru Tsai
Veröffentlicht/Copyright: 11. Februar 2016
Veröffentlichen auch Sie bei De Gruyter Brill

Abstract

The present study used differential scanning calorimetry, thermogravimetric analysis, and UV spectrometry to examine: i) the encapsulation of an organic UV filter 1-(4-methoxyphenyl)-3-(4-tert-butylphenyl)propane-1,3-dione (avobenzone) within modified dextrin and ii) the characteristics of these inclusion complexes (MDA). The properties of avobenzone emulsions with and without encapsulation in modified dextrin, the in vitro UV protection factor, dissolution and release, and the skin penetrability of avobenzone were also examined. The presence of inclusion complexes significantly decreased the tendency of the UV filter to penetrate the skin. In addition, such inclusion complexes should effectively prevent skin damage from radiation extending from the UVA to the UVC.

5

5 References

Anselmi, C., Centini, M., Rossi, C., Ricci, M., Rastrelli, A., Andreassi, M., Buonocore, A., & La Rosa, C. (2002). New microencapsulated sunscreens: Technology and comparative evaluation. International Journal of Pharmaceutics, 242, 207-211. DOI: 10.1016/s0378-5173(02)00159-x.10.1016/S0378-5173(02)00159-XSuche in Google Scholar

Chatelain, E., & Gabard, B. (2001). Photostabilization of butyl methoxydibenzoylmethane (Avobenzone) and ethylhexyl methoxycinnamate by bis-ethylhexyloxyphenol methoxyphenyl triazine (Tinosorb S), a new UV broadband filter. Photochemistry and Photobiology, 74, 401-406. DOI: 10.1562/0031-8655(2001)0740401pobmaa2.0.co2.10.1562/0031-8655(2001)074<0401:POBMAA>2.0.CO;2Suche in Google Scholar

Chatelain, E., Gabard, B., & Surber, C. (2003). Skin penetration and sun protection factor of five UV filters: Effect of the vehicle. Skin Pharmacology and Applied Physiology, 16, 28-35. DOI: 10.1159/000068291.10.1159/000068291Suche in Google Scholar

COLIPA (2007). Guideline for the colorimetric determination of a skin color typing and prediction of the minimal erythemal dose (MED) without UV exposure. Brussels, Belgiumml: COLIPA.Suche in Google Scholar

Damiani, E., Greci, L., Parsons, R., & Knowland, J. (1999). Nitroxide radicals protect DNA from damage when illuminated in vitro in the presence of dibenzoylmethane and a common sunscreen ingredient. Free Radical Biology and Medicine, 26, 809-816. DOI: 10.1016/s0891-5849(98)00292-5.10.1016/S0891-5849(98)00292-5Suche in Google Scholar

Diffey, B. L., & Robson, J. (1989). A new substrate to measure sunscreen protection factors throughout the ultraviolet spectrum. Journal of the Society of Cosmetic Chemists, 40, 127-133.Suche in Google Scholar

Dissanayake, N. S., Greenoak, G. E., & Mason, R. S. (1993). Effects of ultraviolet irradiation on human skin-derived epidermal cells in vitro. Journal of Cellular Physiology, 157, 119-127. DOI: 10.1002/jcp.1041570116.10.1002/jcp.1041570116Suche in Google Scholar

Garoli, D., Pelizzo, M. G., Bernardini, B., Nicolosi, P., & Alaibac, M. (2008). Sunscreen tests: Correspondence between in vitro data and values reported by the manufacturers. Journal of Dermatological Science, 52, 193-204. DOI: 10.1016/j.jdermsci.2008.06.010.10.1016/j.jdermsci.2008.06.010Suche in Google Scholar

Hanson, K. M., Gratton, E., & Bardeen, C. J. (2006). Sunscreen enhancement of UV-induced reactive oxygen species in the skin. Free Radical Biology and Medicine, 41, 12051212. DOI: 10.1016/j.freeradbiomed.2006.06.011.10.1016/j.freeradbiomed.2006.06.011Suche in Google Scholar

Hayden, C. G. J., Cross, S. E., Anderson, C., Saunders, N. A., & Roberts, M. S. (2005). Sunscreen penetration of human skin and related keratinocyte toxicity after topical application. Skin Pharmacology and Physiology, 18, 170-174. DOI: 10.1159/000085861.10.1159/000085861Suche in Google Scholar

Kockler, J., Oelgemöller, M., Robertson, S., & Glass, B. D. (2012). Photostability of sunscreens. Journal of Photochemistry and Photobiology C, 13, 91-110. DOI: 10.1016/j. jphotochemrev.2011.12.001.10.1016/j.jphotochemrev.2011.12.001Suche in Google Scholar

Lin, L. H., & Chou, Y. S. (2010). Surface activity and emulsification properties of hydrophobically modified dextrins. Colloids and Surfaces A, 364, 55-60. DOI: 10.1016/j.colsurfa. 2010.04.033.10.1016/j.colsurfa.2010.04.033Suche in Google Scholar

Mestres, J. P., Duracher, L., Baux, C., Vian, L., & Marti-Mestres, G. (2010). Benzophenone-3 entrapped in solid lipid microspheres: Formulation and in vitro skin evaluation. International Journal of Pharmaceutics, 400, 1-7. DOI: 10.1016/j.ijpharm.2010.07.028.10.1016/j.ijpharm.2010.07.028Suche in Google Scholar

Montenegro, L., Carbone, C., & Puglisi, G. (2011). Vehicle effects on in vitro release and skin permeation of octylmethoxycinnamate from microemulsions. International Journal of Pharmaceutics, 405, 162-168. DOI: 10.1016/j. ijpharm.2010.11.036.10.1016/j.ijpharm.2010.11.036Suche in Google Scholar

Nohynek, G. J., & Schaefer, H. (2001). Benefit and risk of organic ultraviolet filters. Regulatory Toxicology and Pharmacology, 33, 285-299. DOI: 10.1006/rtph.2001.1476.10.1006/rtph.2001.1476Suche in Google Scholar

Olvera-Martinez, B. I., Cazares-Delgadillo, J., Calderilla-Fajardo, S. B., Villalobos-Garcia, R., Ganem-Quintanar, A., & Quintanar-Guerrero, D. (2005). Preparation of polymeric nanocapsules containing octyl methoxycinnamate by the emulsification-diffusion technique: Penetration across the stratum corneum. Journal of Pharmaceutical Sciences, 94, 1552-1559. DOI: 10.1002/jps.20352.10.1002/jps.20352Suche in Google Scholar

Patel, M., Jain, S. K., Yadav, A. K., Gogna, D., & Agrawal, G. P. (2006). Preparation and characterization of oxybenzoneloaded gelatin microspheres for enhancement of sunscreening efficacy. Drug Delivery, 13, 323-330. DOI: 10.1080/1071754 0500398175.10.1080/10717540500398175Suche in Google Scholar

Pathak, M. A. (1991). Ultraviolet radiation and the development of non-melanoma and melanoma skin cancer: Clinical and experimental evidence. Skin Pharmacology and Physiology, 4, 85-94. DOI: 10.1159/000210987.10.1159/000210987Suche in Google Scholar

Perugini, P., Simeoni, S., Scalia, S., Genta, I., Modena, T., Conti, B., & Pavanetto, F. (2002). Effect of nanoparticles encapsulation on the photostability of the sunscreen agent, 2-ethylhexyl-p-methoxycinnamate. International Journal of Pharmaceutics, 246, 37-45. DOI: 10.1016/s0378-5173(02)00 356-3.10.1016/S0378-5173(02)00356-3Suche in Google Scholar

Reece, B. T., Deeds, D., & Rozen, M. (1992). An in vitro method for screening sunscreen formulations for sun protection factor using a full-thickness skin model. Journal of the Society of Cosmetic Chemists, 43, 307-312.Suche in Google Scholar

Roscher, N. M., Lindemann, M. K. O., Kong, S. B., Cho, C.G., & Jiang, P. (1994). Photodecomposition of several compounds commonly used as sunscreen agents. Journal of Photochemistry and Photobiology A, 80, 417-421. DOI: 10.1016/1010-6030(94)01043-9.10.1016/1010-6030(94)01043-9Suche in Google Scholar

Sadick, N. S., Karcher, C., & Palmisano, L. (2009). Cosmetic dermatology of the aging face. Clinics in Dermatology, 27, S3-S12. DOI: 10.1016/j.clindermatol.2008.12.003.10.1016/j.clindermatol.2008.12.003Suche in Google Scholar

Scalia, S., Simeoni, S., Barbieri, A., & Sostero, S. (2002). Influence of hydroxypropyl-ß-cyclodextrin on photo-induced free radical production by the sunscreen agent, butyl-methoxydibenzoylmethane. Journal of Pharmacy and Pharmacology, 54, 1553-1558. DOI: 10.1211/002235702207.10.1211/002235702207Suche in Google Scholar PubMed

Scalia, S., Coppi, G., & Iannuccelli, V. (2011). Microencapsulation of a cyclodextrin complex of the UV filter, butyl methoxydibenzoylmethane: In vivo skin penetration studies. Journal of Pharmaceutical and Biomedical Analysis, 54, 345-350. DOI: 10.1016/j.jpba.2010.09.018.10.1016/j.jpba.2010.09.018Suche in Google Scholar

Schlumpf, M., Schmid, P., Durrer, S., Conscience, M., Maerkel, K., Henseler, M., Gruetter, M., Herzog, I., Reolon,S., Ceccatelli, R., Faass, O., Stutz, E., Jarry, H., Wuttke, W., & Lichtensteiger, W. (2004). Endocrine activity and developmental toxicity of cosmetic UV filters: An update. Toxicology, 205, 113-122. DOI: 10.1016/j.tox.2004.06.043.10.1016/j.tox.2004.06.043Suche in Google Scholar

Shah, V. P., Elkins, J., Lam, S. Y., & Skelly, J. P. (1989). Determination of in vitro drug release from hydrocortisone creams. International Journal of Pharmaceutics, 53, 53-59. DOI: 10.1016/0378-5173(89)90361-x.10.1016/0378-5173(89)90361-XSuche in Google Scholar

Springsteen, A., Yurek, R., Frazier, M., & Carr, K. F. (1999). In vitro measurement of sun protection factor of sunscreens by diffusive transmittance. Analytica Chimica Acta, 380, 155164. DOI: 10.1016/s0003-2670(98)00577-7.10.1016/S0003-2670(98)00577-7Suche in Google Scholar

Tarras-Wahlberg, N., Stenhagen, G., Larko, O., Rosen, A., Wennberg, A. M., & Wennerstrom, O. (1999). Changes in ultraviolet absorption of sunscreens after ultraviolet irradiation. Journal of Investigative Dermatology, 113, 547-553. DOI: 10.1046/j.1523-1747.1999.00721.x.10.1046/j.1523-1747.1999.00721.xSuche in Google Scholar

Treffel, P., & Gabard, B. (1996). Skin penetration and sun protection factor of ultra-violet filters from two vehicles. Pharmaceutical Research, 13, 770-774. DOI: 10.1023/a:10160120 19483.10.1023/A:1016012019483Suche in Google Scholar

Wang, H. R., & Chen, K. M. (2006). Preparation and surface active properties of biodegradable dextrin derivative surfactants. Colloids and Surfaces A, 281, 190-193. DOI: 10.1016/j.colsurfa.2006.02.039.10.1016/j.colsurfa.2006.02.039Suche in Google Scholar

Wang, S. Q., Stanfield, J. W., & Osterwalder, U. (2008). In vitro assessments of UVA protection by popular sunscreens available in the United States. Journal of the American Academy of Dermatology, 59, 934-942. DOI: 10.1016/j.jaad.2008.07.043.10.1016/j.jaad.2008.07.043Suche in Google Scholar

World Health Organization (2010). Ultraviolet radiation and the INTERSUN Programme. Retrieved February, 2010, from http://www.who.int/uv/faq/skincancer/en/index1.htmlSuche in Google Scholar

Wu, H. L., Ramachandran, C., Weiner, N. D., & Roessler, B. J. (2001). Topical transport of hydrophilic compounds using water-in-oil nanoemulsions. International Journal of Pharmaceutics, 220, 63-75. DOI: 10.1016/s0378-5173(01)00671-8.10.1016/S0378-5173(01)00671-8Suche in Google Scholar

Yang, J., Wiley, C. J., Godwin, D. A., & Felton, L. A. (2008). Influence of hydroxypropyl-ß-cyclodextrin on transdermal penetration and photostability of avobenzone. European Journal of Pharmaceutics and Biopharmaceutics, 69, 605-612. DOI: 10.1016/j.ejpb.2007.12.015. 10.1016/j.ejpb.2007.12.015Suche in Google Scholar PubMed

Received: 2015-9-11
Revised: 2015-11-23
Accepted: 2015-11-26
Published Online: 2016-2-11
Published in Print: 2016-6-1

© 2016 Institute of Chemistry, Slovak Academy of Sciences

Artikel in diesem Heft

  1. Original Paper
  2. A practical approach to non-spectral interferences elimination in inductively coupled plasma optical emission spectrometry
  3. Original Paper
  4. Two 1,8-naphthalimide-based proton-receptor fluorescent probes for pH determination
  5. Original Paper
  6. Fabrication of amperometric cholesterol biosensor based on SnO2 nanoparticles and Nafion-modified carbon paste electrode
  7. Original Paper
  8. Preparation and catalytic performance of quaternary ammonium base resin for methanolysis of natural phosphatidylcholine
  9. Original Paper
  10. Optimisation of microwave-assisted extraction from Phyllanthus amarus for phenolic compounds-enriched extracts and antioxidant capacity
  11. Original Paper
  12. Red clover (Trifolium pratense L.) honey: volatiles chemical-profiling and unlocking antioxidant and anticorrosion capacity
  13. Original Paper
  14. Application of vacuum membrane distillation for concentration of organic solutions
  15. Original Paper
  16. Correlations for mixing energy in processes using Rushton turbine mixer‡
  17. Original Paper
  18. Recovery of Au(III) ions by Au(III)-imprinted hydrogel
  19. Original Paper
  20. Initiation behaviour in hydrogenation of pyrolysis gasoline over presulphided Ni-Mo-Zn/Al2O3 catalyst
  21. Original Paper
  22. Methodology considering surface roughness in UV water disinfection reactors
  23. Original Paper
  24. Comparison of changes of basic parameters of asphalt caused by various additives
  25. Original Paper
  26. Effect of carbon nanotube modification on poly (butylene terephthalate)-based composites
  27. Original Paper
  28. Evaluation of influence of selected metal cations on antioxidant activity of extracts from savory (Satureja hortensis)
  29. Original Paper
  30. Radical-scavenging activity of glutathione, chitin derivatives and their combination
  31. Original Paper
  32. Piroxicam /β-cyclodextrin complex included in cellulose derivatives-based matrix microspheres as new solid dispersion-controlled release formulations
  33. Original Paper
  34. Avobenzone encapsulated in modified dextrin for improved UV protection and reduced skin penetration
  35. Original Paper
  36. Analysis of the dynamics of laser induced plume propagation from liquid matrix using fast photography
  37. Original Paper
  38. OH-initiated oxidation mechanism and kinetics of organic sunscreen benzophenone-3: A theoretical study
Heruntergeladen am 28.12.2025 von https://www.degruyterbrill.com/document/doi/10.1515/chempap-2016-0021/html?lang=de
Button zum nach oben scrollen