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Determination of urinary stone composition based on stone morphology: a prospective study of 325 consecutive patients in an emerging country
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Silvia F.R. da Silva
Veröffentlicht/Copyright:
12. März 2009
Abstract
Background: Urolithiasis is a common disease that is increasing throughout the world. This study aimed at determining the composition of urinary stones in patients with renal lithiasis in an emerging country.
Methods: A morphological analysis was performed on 340 urinary stones from 325 consecutive patients from Brazil with lithiasis.
Results and conclusions: Among the 340 stones analyzed, 34.7% were pure. The most frequent stone was calcium oxalate (CaOx) (59.3%), followed by uric acid (23.7%). CaOx was more frequently seen in women (p=0.024), while uric acid was more common in men (p<0.001). Among the mixed stones, CaOx (67.1%) was the most frequent major component, followed by carbapatite (11.2%) and struvite (7.9%). CaOx (p<0.001) and uric acid (p=0.014) were more frequently the major components in men, while carbapatite (p<0.001) and struvite (p=0.011) were more frequent in women. The major component of both pure and mixed stones was CaOx (65.1%), followed by uric acid (10.9%), carbapatite (10%), struvite (6.7%), ammonium urate (5.1%), cystine (1.8%) and protein (0.4%). These findings may be related to regional factors, such as weather and nutritional habits.
Clin Chem Lab Med 2009;47:561–4.
Received: 2008-11-1
Accepted: 2009-2-3
Published Online: 2009-03-12
Published in Print: 2009-05-01
©2009 by Walter de Gruyter Berlin New York
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Schlagwörter für diesen Artikel
calcium oxalate;
composition;
risk factors;
stone morphology;
urinary stone
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- Pharmacogenetics of vitamin K antagonists: useful or hype?
- Genetics and Molecular Diagnostics
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- General Clinical Chemistry and Laboratory Medicine
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