Gene expression profiling in human cardiovascular disease
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Marja Steenman
Abstract
Gene expression profiling studies in human diseases have allowed better understanding of pathophysiological processes. In addition, they may lead to the development of new clinical tools to improve diagnosis and prognosis of patients. Most of these studies have been successfully performed for human cancers. Inspired by these results, researchers in the cardiovascular field have also started using large-scale transcriptional analysis to better understand and classify human cardiovascular disease. Here we provide an overview of the literature revealing new cardiac disease markers and encouraging results for further development of the expression profiling strategy for future clinical applications in cardiology.
References
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©2005 by Walter de Gruyter Berlin New York
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Articles in the same Issue
- Inter-individual variation of inflammatory markers of cardiovascular risks and diseases
- “Coelionomics”: towards understanding the molecular pathology of coeliac disease
- Gene expression profiling in human cardiovascular disease
- A common CYP1B1 polymorphism is associated with 2-OHE1/16-OHE1 urinary estrone ratio
- A quantitative RT-PCR method to determine topoisomerase I mRNA levels in human tissue samples
- Insulin sensitivity and counter-regulatory hormones in hypothyroidism and during thyroid hormone replacement therapy
- Linearity and detection limit in the measurement of serum M-protein with the capillary zone electrophoresis system Capillarys ®
- Quantitative measurement of ketone bodies in urine using reflectometry
- Quantification of voriconazole in plasma by liquid chromatography-tandem mass spectrometry
- Determination of the antioxidant capacity in blood
- High-workload endurance training may increase serum ischemia-modified albumin concentrations
- Advanced oxidation protein products in serum of patients with myotonic disease type I: association with serum γ-glutamyltransferase and disease severity
- Effectiveness of different methods for anti-Sm antibody identification. A multicentre study
- Quality control in neutrophil granulocyte (PMN) concentrates by flow cytometry
- Circadian variation of holo-transcobalamin (holo-TC) and related markers
- Elevated levels of plasma homocysteine in postmenopausal women in Burkina Faso
- Allergy testing on the IMMULITE 2000 Random-Access immunoanalyzer – a clinical evaluation study
- Evaluation of the ABX Pentra 400: a newly available clinical chemistry analyser
