Aryl hydrocarbon receptor agonists directly activate estrogen receptor α in MCF-7 breast cancer cells

References

Abdelrahim, M., Smith R. III, and Safe, S. (2003). Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells. Mol. Pharmacol.63, 1373–1381.10.1124/mol.63.6.1373Search in Google Scholar

Abdelrahim, M., Ariazi, E., Kim, K., Khan, S., Barhoumi, R., Burghardt, R., Liu, S., Hill, D., Finnell, R., Wlodarczyk, B., et al. (2006). 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor α. Cancer Res.66, 2459–2467.10.1158/0008-5472.CAN-05-3132Search in Google Scholar

Beischlag, T.V. and Perdew, G.H. (2005). ERa-AHR-ARNT protein-protein interactions mediate estradiol-dependent transrepression of dioxin-inducible gene transcription. J. Biol. Chem.280, 21607–21611.10.1074/jbc.C500090200Search in Google Scholar

Bjeldanes, L.F., Kim, J.Y., Grose, K.R., Bartholomew, J.C., and Bradfield, C.A. (1991). Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo-comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Proc. Natl. Acad. Sci. USA88, 9543–9547.10.1073/pnas.88.21.9543Search in Google Scholar

Bradfield, C.A. and Poland, A. (1988). A competitive binding assay for 2,3,7,8-tetrachlorodibenzo-p-dioxin and related ligands of the Ah receptor. Mol. Pharmacol.34, 682–688.Search in Google Scholar

Denison, M.S. and Nagy, S.R. (2003). Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu. Rev. Pharmacol. Toxicol.43, 309–334.10.1146/annurev.pharmtox.43.100901.135828Search in Google Scholar

Gould, J.C., Leonard, L.S., Maness, S.C., Wagner, B.L., Connor, K., Zacharewski, T., Safe, S., McDonnell, D.P., and Gaido, K.W. (1998). Bisphenol A interacts with the estrogen receptor a in a distinct manner from estradiol. Mol. Cell. Endocrinol.142, 203–214.10.1016/S0303-7207(98)00084-7Search in Google Scholar

Hoivik, D., Willett, K., Wilson, C., and Safe, S. (1997). Estrogen does not inhibit 2, 3, 7, 8-tetraclorodibenzo-p-dioxin-mediated effects in MCF-7 and Hepa 1c1c7 cells. J. Biol. Chem.272, 30270–30274.10.1074/jbc.272.48.30270Search in Google Scholar PubMed

Kharat, I. and Saatcioglu, F. (1996). Antiestrogenic effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin are mediated by direct transcriptional interference with the liganded estrogen receptor. J. Biol. Chem.271, 10533–10537.10.1074/jbc.271.18.10533Search in Google Scholar PubMed

Kuiper, G.G., Lemmen, J.G., Carlsson, B., Corton, J.C., Safe, S., Van der Saag, P.T., Van der Burg, B., and Gustafsson, J.-Å. (1998). Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β. Endocrinology139, 4252–4263.10.1210/endo.139.10.6216Search in Google Scholar PubMed

Lee, H.J., Chattopadhyay, S., Gong, E.Y., Ahn, R.S., and Lee, K. (2003). Antiandrogenic effects of bisphenol A and nonylphenol on the function of androgen receptor. Toxicol. Sci.75, 40–46.10.1093/toxsci/kfg150Search in Google Scholar PubMed

Liu, H., Wormke, M., Safe, S., and Bjeldanes, L.F. (1994). Indolo[3,2-b]carbazole: a dietary factor which exhibits both antiestrogenic and estrogenic activity. J. Natl. Cancer Inst.86, 1758–1765.10.1093/jnci/86.23.1758Search in Google Scholar

Matthews, J., Wihlen, B., Thomsen, J., and Gustafsson, J.A. (2005). Aryl hydrocarbon receptor-mediated transcription: ligand-dependent recruitment of estrogen receptor α to 2,3,7,8-tetrachlorodibenzo-p-dioxin-responsive promoters. Mol. Cell. Biol.25, 5317–5328.10.1128/MCB.25.13.5317-5328.2005Search in Google Scholar

Ohtake, F., Takeyama K., Matsumoto T., Kitagawa H., Yamamoto Y., Nohara K., Tohyama C., Krust A., Mimura J., Chambon P., et al. (2003). Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature423, 545–550.10.1038/nature01606Search in Google Scholar

Pearce, S.T., Liu, H., Radhakrishnan, I., Abdelrahim, M., Safe, S., and Jordan, V.C. (2004). Interaction of the aryl hydrocarbon receptor ligand 6-methyl-1,3,8-trichlorodibenzofuran (MCDF) with estrogen receptor α. Cancer Res.64, 2889–2897.10.1158/0008-5472.CAN-03-1770Search in Google Scholar

Piskorska-Pliszczynska, J., Keys, B., Safe, S., and Newman, M.S. (1986). The cytosolic receptor binding affinities and AHH induction potencies of 29 polynuclear aromatic hydrocarbons. Toxicol. Lett.34, 67–74.10.1016/0378-4274(86)90146-3Search in Google Scholar

Poland, A. and Knutson, J.C. (1982). 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons. Examinations of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol.22, 517–554.10.1146/annurev.pa.22.040182.002505Search in Google Scholar

Poland, A., Glover, E., and Kende, A.S. (1976). Stereospecific, high affinity binding of 2,3,7,8-tetrachlorodibenzo-p-dioxin by hepatic cytosol: evidence that the binding species is receptor for induction of aryl hydrocarbon hydroxylase. J. Biol. Chem.251, 4936–4946.10.1016/S0021-9258(17)33205-2Search in Google Scholar

Safe, S. and Wormke, M. (2003). Inhibitory aryl hydrocarbon-estrogen receptor a crosstalk and mechanisms of action. Chem. Res. Toxicol.16, 807–816.10.1021/tx034036rSearch in Google Scholar

Safe, S. (1990). Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs) and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). CRC Crit. Rev. Toxicol.21, 51–88.10.3109/10408449009089873Search in Google Scholar

Safe, S. (1995). Modulation of gene expression and endocrine response pathways by 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compounds. Pharmacol. Therap.67, 247–281.10.1016/0163-7258(95)00017-BSearch in Google Scholar

Wilson, C.L. and Safe, S. (1998). Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses. Toxicol. Pathol.26, 657–671.10.1177/019262339802600510Search in Google Scholar PubMed

Wormke, M., Stoner, M., Saville, B., Walker, K., Abdelrahim, M., Burghardt, R., and Safe, S. (2003). The aryl hydrocarbon receptor mediates degradation of the estrogen receptor a through activation of proteasomes. Mol. Cell. Biol.23, 1843–1855.10.1128/MCB.23.6.1843-1855.2003Search in Google Scholar PubMed PubMed Central

Zhang, S., Qin, C., and Safe, S.H. (2003). Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context. Environ. Health Persp.111, 1877–1882.10.1289/ehp.6322Search in Google Scholar PubMed PubMed Central