Impact of the arylhydrocarbon receptor on eugenol- and isoeugenol-induced cell cycle arrest in human immortalized keratinocytes (HaCaT)

References

Abdelrahim, M., Smith, R. 3rd, and Safe, S. (2003). Aryl hydrocarbon receptor gene silencing with small inhibitory RNA differentially modulates Ah-responsiveness in MCF-7 and HepG2 cancer cells. Mol. Pharmacol.63, 1373–1381.10.1124/mol.63.6.1373Search in Google Scholar

Bauman, J.W., Goldsworthy, T.L., Dunn, C.S., and Fox, T.R. (1995). Inhibitory effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on rat hepatocyte proliferation induced by 2/3 partial hepatectomy. Cell Prolif.28, 437–451.10.1111/j.1365-2184.1995.tb00084.xSearch in Google Scholar

Carver, L.A. and Bradfield, C.A. (1997). Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. J. Biol. Chem.272, 11452–11456.10.1074/jbc.272.17.11452Search in Google Scholar

Elferink, C.J. (2003). Aryl hydrocarbon receptor-mediated cell cycle control. Prog. Cell Cycle Res.5, 261–267.Search in Google Scholar

Elferink, C.J., Ge, N.L., and Levine, A. (2001). Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein. Mol. Pharmacol.59, 664–673.10.1124/mol.59.4.664Search in Google Scholar

Elizondo, G., Fernandez-Salguero, P., Sheikh, M.S., Kim, G.Y., Fornace, A.J., Lee, K.S., and Gonzalez, F.J. (2000). Altered cell cycle control at the G₂/M phases in aryl hydrocarbon receptor-null embryo fibroblasts. Mol. Pharmacol.57, 1056–1063.Search in Google Scholar

Gasiewicz, T.A., Kende, A.S., Rucci, G., Whitney, B., and Willey, J.J. (1996). Analysis of structural requirements for Ah receptor antagonist activity: ellipticines, flavones, and related compounds. Biochem. Pharmacol.52, 1787–1803.10.1016/S0006-2952(96)00600-4Search in Google Scholar

Ge, N.L. and Elferink, C.J. (1998). A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle. J. Biol. Chem.273, 22708–22713.10.1074/jbc.273.35.22708Search in Google Scholar

Ghosh, R., Nadiminty, N., Fitzpatrick, J.E., Alworth, W.L., Slaga, T.J., and Kumar, A.P. (2005). Eugenol causes melanoma growth suppression through inhibition of E2F1 transcriptional activity. J. Biol. Chem.280, 5812–5819.10.1074/jbc.M411429200Search in Google Scholar

Gierthy, J.F. and Crane, D. (1984). Reversible inhibition of in vitro epithelial cell proliferation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol.74, 91–98.10.1016/0041-008X(84)90274-6Search in Google Scholar

Gonzalez, F.J. and Fernandez-Salguero, P. (1998). The aryl hydrocarbon receptor: studies using the AHR-null mice. Drug Metab. Dispos.26, 1194–1198.Search in Google Scholar

Hankinson, O. (1995). The aryl hydrocarbon receptor complex. Annu. Rev. Pharmacol. Toxicol.35, 307–340.10.1146/annurev.pa.35.040195.001515Search in Google Scholar PubMed

Huang, G. and Elferink, C.J. (2005). Multiple mechanisms are involved in Ah receptor-mediated cell cycle arrest. Mol. Pharmacol.67, 88–96.10.1124/mol.104.002410Search in Google Scholar PubMed

Hushka, D.R. and Greenlee, W.F. (1995). 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits DNA synthesis in rat primary hepatocytes. Mutat. Res.333, 89–99.10.1016/0027-5107(95)00135-2Search in Google Scholar

Ikuta, T., Kobayashi, Y., and Kawajiri, K. (2004). Cell density regulates intracellular localization of aryl hydrocarbon receptor. J. Biol. Chem.279, 19209–19216.10.1074/jbc.M310492200Search in Google Scholar PubMed

Ito, T., Tsukumo, S., Suzuki, N., Motohashi, H., Yamamoto, M., Fujii-Kuriyama, Y., Mimura, J., Lin, T.M., Peterson, R.E., Tohyama, C., and Nohara, K. (2004). A constitutively active arylhydrocarbon receptor induces growth inhibition of jurkat T cells through changes in the expression of genes related to apoptosis and cell cycle arrest. J. Biol. Chem.279, 25204–25210.10.1074/jbc.M402143200Search in Google Scholar PubMed

Jin, D.Q., Jung, J.W., Lee, Y.S., and Kim, J.A. (2004). 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits cell proliferation through arylhydrocarbon receptor-mediated G1 arrest in SK-N-SH human neuronal cells. Neurosci. Lett.363, 69–72.10.1016/j.neulet.2004.03.047Search in Google Scholar PubMed

Kazlauskas, A., Poellinger, L., and Pongratz, I. (1999). Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (aryl hydrocarbon) receptor. J. Biol. Chem.274, 13519–13524.10.1074/jbc.274.19.13519Search in Google Scholar PubMed

Kolluri, S.K., Weiss, C., Koff, A., and Gottlicher, M. (1999). p27(Kip1) induction and inhibition of proliferation by the intracellular Ah receptor in developing thymus and hepatoma cells. Genes Dev.13, 1742–1753.10.1101/gad.13.13.1742Search in Google Scholar PubMed PubMed Central

Leurs, C., Jansen, M., Pollok, K.E., Heinkelein, M., Schmidt, M., Wissler, M., Lindemann, D., Von Kalle, C., Rethwilm, A., Williams, D.A., and Hanenberg, H. (2003). Comparison of three retroviral vector systems for transduction of nonobese diabetic/severe combined immunodeficiency mice repopulating human CD34⁺ cord blood cells. Hum. Gene Ther.14, 509–519.10.1089/104303403764539305Search in Google Scholar PubMed

Levy, L. and Hill, C.S. (2005). Smad4 dependency defines two classes of transforming growth factor β (TGF-β) target genes and distinguishes TGF-β-induced epithelial-mesenchymal transition from its antiproliferative and migratory responses. Mol. Cell. Biol.25, 8108–8125.10.1128/MCB.25.18.8108-8125.2005Search in Google Scholar PubMed PubMed Central

Lu, Y.F., Santostefano, M., Cunningham, B.D., Threadgill, M.D., and Safe, S. (1995). Identification of 3'-methoxy-4'-nitroflavone as a pure aryl hydrocarbon (Ah) receptor antagonist and evidence for more than one form of the nuclear Ah receptor in MCF-7 human breast cancer cells. Arch. Biochem. Biophys.316, 470–477.10.1006/abbi.1995.1062Search in Google Scholar PubMed

Ma, Q. (2001). Induction of CYP1A1. The AhR/DRE paradigm: transcription, receptor regulation, and expanding biological roles. Curr. Drug Metab.2, 149–164.Search in Google Scholar

Ma, Q. and Whitlock Jr., J.P. (1996). The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin. Mol. Cell Biol.16, 2144–2150.10.1128/MCB.16.5.2144Search in Google Scholar PubMed PubMed Central

Ma, Q. and Whitlock Jr., J.P. (1997). A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Biol. Chem.272, 8878–8884.10.1074/jbc.272.14.8878Search in Google Scholar

Mace, K., Bowman, E., Vautravers, P., Shields, P., Harris, C., and Pfeifer, A. (1998). Characterization of xenobiotic-metabolizing enzyme expression in human bronchial mucosa and peripheral lung tissues. Eur. J. Cancer34, 914–920.10.1016/S0959-8049(98)00034-3Search in Google Scholar

Marlowe, J.L., Knudsen, E.S., Schwemberger, S., and Puga, A. (2004). The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phase-specific gene expression. J. Biol. Chem.279, 29013–29022.10.1074/jbc.M404315200Search in Google Scholar

Meyer, B.K., Pray-Grant, M.G., Vanden Heuvel, J.P., and Perdew, G.H. (1998). Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity. Mol. Cell. Biol.18, 978–988.10.1128/MCB.18.2.978Search in Google Scholar

Perdew, G.H. (1988). Association of the Ah receptor with the 90-kDa heat shock protein. J. Biol. Chem.263, 13802–13805.10.1016/S0021-9258(18)68314-0Search in Google Scholar

Puga, A., Barnes, S.J., Dalton, T.P., Chang, C., Knudsen, E.S., and Maier, M.A. (2000). Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. J. Biol. Chem.275, 2943–2950.10.1074/jbc.275.4.2943Search in Google Scholar

Puga, A., Marlowe, J., Barnes, S., Chang, C.Y., Maier, A., Tan, Z., Kerzee, J.K., Chang, X., Strobeck, M., and Knudsen, E.S. (2002a). Role of the aryl hydrocarbon receptor in cell cycle regulation. Toxicology181–182, 171–177.10.1016/S0300-483X(02)00276-7Search in Google Scholar

Puga, A., Xia, Y., and Elferink, C. (2002b). Role of the aryl hydrocarbon receptor in cell cycle regulation. Chem. Biol. Interact.141, 117–130.10.1016/S0009-2797(02)00069-8Search in Google Scholar

Ray, S.S. and Swanson, H.I. (2004). Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a. J. Biol. Chem.279, 27187–27193.10.1074/jbc.M402771200Search in Google Scholar PubMed

Schmidt, J.V. and Bradfield, C.A. (1996). Ah receptor signaling pathways. Annu. Rev. Cell Dev. Biol.12, 55–89.10.1146/annurev.cellbio.12.1.55Search in Google Scholar PubMed

Sieben, S., Hertl, M., Al Masaoudi, T., Merk, H.F., and Blomeke, B. (2001). Characterization of T cell responses to fragrances. Toxicol. Appl. Pharmacol.172, 172–178.10.1006/taap.2001.9125Search in Google Scholar PubMed

Swanson, H.I. (2004). Cytochrome P450 expression in human keratinocytes: an aryl hydrocarbon receptor perspective. Chem. Biol. Interact.149, 69–79.10.1016/j.cbi.2004.08.006Search in Google Scholar PubMed

Tauchi, M., Hida, A., Negishi, T., Katsuoka, F., Noda, S., Mimura, J., Hosoya, T., Yanaka, A., Aburatani, H., Fujii-Kuriyama, Y., et al. (2005). Constitutive expression of aryl hydrocarbon receptor in keratinocytes causes inflammatory skin lesions. Mol. Cell. Biol.25, 9360–9368.10.1128/MCB.25.21.9360-9368.2005Search in Google Scholar PubMed PubMed Central

Vanden Heuvel, J.P., Clark, G.C., Kohn, M.C., Tritscher, A.M., Greenlee, W.F., Lucier, G.W., and Bell, D.A. (1994). Dioxin-responsive genes: examination of dose–response relationships using quantitative reverse transcriptase-polymerase chain reaction. Cancer Res.54, 62–68.Search in Google Scholar

Vaziri, C. and Faller, D.V. (1997). A benzo[a]pyrene-induced cell cycle checkpoint resulting in p53-independent G1 arrest in 3T3 fibroblasts. J. Biol. Chem.272, 2762–2769.10.1074/jbc.272.5.2762Search in Google Scholar PubMed

Wang, W., Smith, R. 3rd, and Safe, S. (1998). Aryl hydrocarbon receptor-mediated antiestrogenicity in MCF-7 cells: modulation of hormone-induced cell cycle enzymes. Arch. Biochem. Biophys.356, 239–248.10.1006/abbi.1998.0782Search in Google Scholar PubMed

Weiss, C., Kolluri, S.K., Kiefer, F., and Gottlicher, M. (1996). Complementation of Ah receptor deficiency in hepatoma cells: negative feedback regulation and cell cycle control by the Ah receptor. Exp. Cell Res.226, 154–163.10.1006/excr.1996.0214Search in Google Scholar PubMed

Wiznerowicz, M. and Trono, D. (2003). Conditional suppression of cellsular genes: lentivirus vector-mediated drug-inducible RNA interference. J. Virol.77, 8957–8961.10.1128/JVI.77.16.8957-8951.2003Search in Google Scholar PubMed PubMed Central