Chapter 2 Micro/nanoemulsions in dermatology for enhanced therapeutic solutions
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Ashish Kumar Pandey
Abstract
Dermatological treatments often encounter obstacles such as poor drug penetration, instability of active ingredients, and undesirable side effects associated with conventional topical formulations. Micro- and nanoemulsions have emerged as advanced delivery systems capable of overcoming these limitations. Owing to their unique nanoscale architecture, these formulations enhance drug solubilization, stability, and controlled release, while minimizing irritation and systemic exposure. In dermatology, micro/nanoemulsions enable noninvasive, site-specific therapies for a range of skin disorders, including chronic and inflammatory conditions. Innovations such as temperature-, enzyme-, and light/magnetic-responsive emulsions further optimize drug delivery, tailoring treatment to individual patient needs. Ensuring formulation stability and extended shelf life requires careful selection of excipients, packaging materials, and manufacturing techniques. This work presents a comprehensive overview of the structural design, penetration mechanisms, and clinical potential of micro/nanoemulsions, underscoring their transformative role in dermatological therapeutics.
Abstract
Dermatological treatments often encounter obstacles such as poor drug penetration, instability of active ingredients, and undesirable side effects associated with conventional topical formulations. Micro- and nanoemulsions have emerged as advanced delivery systems capable of overcoming these limitations. Owing to their unique nanoscale architecture, these formulations enhance drug solubilization, stability, and controlled release, while minimizing irritation and systemic exposure. In dermatology, micro/nanoemulsions enable noninvasive, site-specific therapies for a range of skin disorders, including chronic and inflammatory conditions. Innovations such as temperature-, enzyme-, and light/magnetic-responsive emulsions further optimize drug delivery, tailoring treatment to individual patient needs. Ensuring formulation stability and extended shelf life requires careful selection of excipients, packaging materials, and manufacturing techniques. This work presents a comprehensive overview of the structural design, penetration mechanisms, and clinical potential of micro/nanoemulsions, underscoring their transformative role in dermatological therapeutics.
Kapitel in diesem Buch
- Frontmatter I
- Foreword V
- Foreword VII
- Contents V
- List of contributing authors IX
- Introduction 1
- Chapter 1 Techniques for characterizing micro/nanoemulsions in pharmaceutical formulations 9
- Chapter 2 Micro/nanoemulsions in dermatology for enhanced therapeutic solutions 49
- Chapter 3 Harnessing micro/nanoemulsion for transnasal drug delivery with enhanced efficacy and precision 79
- Chapter 4 Micro/nanoemulsions redefining cosmeceutical formulation for optimal skin health 107
- Chapter 5 Accelerating recovery through advanced wound healing applications of micro/nanoemulsions 127
- Chapter 6 Precision oncology: nanoemulsions as pioneers in the delivery of anticancer agents, immunomodulators, and vaccines 171
- Chapter 7 Cutting-edge innovations: advances and applications of micro/nanoemulsions in gel formulations 211
- Chapter 8 Clinical frontiers and regulatory status of micro/nanoemulsions 251
- Chapter 9 Future prospects of micro/nanoemulsions in enhancing drug performance 269
- Index 289
Kapitel in diesem Buch
- Frontmatter I
- Foreword V
- Foreword VII
- Contents V
- List of contributing authors IX
- Introduction 1
- Chapter 1 Techniques for characterizing micro/nanoemulsions in pharmaceutical formulations 9
- Chapter 2 Micro/nanoemulsions in dermatology for enhanced therapeutic solutions 49
- Chapter 3 Harnessing micro/nanoemulsion for transnasal drug delivery with enhanced efficacy and precision 79
- Chapter 4 Micro/nanoemulsions redefining cosmeceutical formulation for optimal skin health 107
- Chapter 5 Accelerating recovery through advanced wound healing applications of micro/nanoemulsions 127
- Chapter 6 Precision oncology: nanoemulsions as pioneers in the delivery of anticancer agents, immunomodulators, and vaccines 171
- Chapter 7 Cutting-edge innovations: advances and applications of micro/nanoemulsions in gel formulations 211
- Chapter 8 Clinical frontiers and regulatory status of micro/nanoemulsions 251
- Chapter 9 Future prospects of micro/nanoemulsions in enhancing drug performance 269
- Index 289
