Chapter 6 Precision oncology: nanoemulsions as pioneers in the delivery of anticancer agents, immunomodulators, and vaccines
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Amrita Thakur
Abstract
Precision oncology represents a paradigm shift in cancer treatment, emphasizing tailored therapeutic strategies based on individual patient profiles. Among the innovative drug delivery systems revolutionizing this field, micro- and nanoemulsions have emerged as promising carriers for anticancer agents, immunomodulators, and vaccines. These colloidal systems offer several advantages, including enhanced solubility of poorly water-soluble drugs, targeted delivery, controlled release, and reduced systemic toxicity. This chapter delves into the design, formulation, and optimization of nanoemulsions, highlighting their physicochemical properties and how these contribute to improved therapeutic outcomes in oncology. Emphasis is placed on their role in delivering chemotherapeutic agents with precision, modulating immune responses for immunotherapy, and serving as platforms for cancer vaccines. The integration of these systems with advanced targeting ligands, imaging agents, and personalized medicine approaches is also explored, underscoring their transformative potential in cancer care. The chapter concludes with a discussion of current challenges, regulatory perspectives, and future directions for clinical translation.
Abstract
Precision oncology represents a paradigm shift in cancer treatment, emphasizing tailored therapeutic strategies based on individual patient profiles. Among the innovative drug delivery systems revolutionizing this field, micro- and nanoemulsions have emerged as promising carriers for anticancer agents, immunomodulators, and vaccines. These colloidal systems offer several advantages, including enhanced solubility of poorly water-soluble drugs, targeted delivery, controlled release, and reduced systemic toxicity. This chapter delves into the design, formulation, and optimization of nanoemulsions, highlighting their physicochemical properties and how these contribute to improved therapeutic outcomes in oncology. Emphasis is placed on their role in delivering chemotherapeutic agents with precision, modulating immune responses for immunotherapy, and serving as platforms for cancer vaccines. The integration of these systems with advanced targeting ligands, imaging agents, and personalized medicine approaches is also explored, underscoring their transformative potential in cancer care. The chapter concludes with a discussion of current challenges, regulatory perspectives, and future directions for clinical translation.
Chapters in this book
- Frontmatter I
- Foreword V
- Foreword VII
- Contents V
- List of contributing authors IX
- Introduction 1
- Chapter 1 Techniques for characterizing micro/nanoemulsions in pharmaceutical formulations 9
- Chapter 2 Micro/nanoemulsions in dermatology for enhanced therapeutic solutions 49
- Chapter 3 Harnessing micro/nanoemulsion for transnasal drug delivery with enhanced efficacy and precision 79
- Chapter 4 Micro/nanoemulsions redefining cosmeceutical formulation for optimal skin health 107
- Chapter 5 Accelerating recovery through advanced wound healing applications of micro/nanoemulsions 127
- Chapter 6 Precision oncology: nanoemulsions as pioneers in the delivery of anticancer agents, immunomodulators, and vaccines 171
- Chapter 7 Cutting-edge innovations: advances and applications of micro/nanoemulsions in gel formulations 211
- Chapter 8 Clinical frontiers and regulatory status of micro/nanoemulsions 251
- Chapter 9 Future prospects of micro/nanoemulsions in enhancing drug performance 269
- Index 289
Chapters in this book
- Frontmatter I
- Foreword V
- Foreword VII
- Contents V
- List of contributing authors IX
- Introduction 1
- Chapter 1 Techniques for characterizing micro/nanoemulsions in pharmaceutical formulations 9
- Chapter 2 Micro/nanoemulsions in dermatology for enhanced therapeutic solutions 49
- Chapter 3 Harnessing micro/nanoemulsion for transnasal drug delivery with enhanced efficacy and precision 79
- Chapter 4 Micro/nanoemulsions redefining cosmeceutical formulation for optimal skin health 107
- Chapter 5 Accelerating recovery through advanced wound healing applications of micro/nanoemulsions 127
- Chapter 6 Precision oncology: nanoemulsions as pioneers in the delivery of anticancer agents, immunomodulators, and vaccines 171
- Chapter 7 Cutting-edge innovations: advances and applications of micro/nanoemulsions in gel formulations 211
- Chapter 8 Clinical frontiers and regulatory status of micro/nanoemulsions 251
- Chapter 9 Future prospects of micro/nanoemulsions in enhancing drug performance 269
- Index 289
