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Chapter 15 Microbial production of amino acids and peptides

  • K. W. A. Madhushan , W. M. D. M. Wickramasinghe , H. M. A. M. Herath , M. A. Madushani , H. H. Nethma , K. R. E. Padmathilake und M. C. M. Zakeel
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Biorationals and Biopesticides
Ein Kapitel aus dem Buch Biorationals and Biopesticides

Abstract

Amino acids and peptides are essential components in many industries, including biotechnology, agriculture, and medicine. Due to its effectiveness and scalability, microbial synthesis of amino acids and peptides has become a potential strategy. This chapter offers a comprehensive summary of microbial metabolism, manufacturing techniques, recent developments, production issues, and future prospects of amino acids and peptides. The complex enzymatic mechanisms and pathways involved in microbial amino acid metabolism are explored, highlighting the importance of carbon and nitrogen supplies and the key enzymes and biosynthesis pathways. Various microbial species are compared for amino acid production, including fermentation and biotransformation processes. The benefits and drawbacks of microbial amino acid synthesis are examined. Additionally, microbial peptide synthesis is investigated, covering species and production methods such as fermentation and solid-state fermentation and discussing the advantages and limitations. The book chapter also reviews the recent advancements in metabolic engineering, synthetic biology, and genetic engineering that have enhanced amino acid and peptide production by microbial strains. The diverse applications of amino acids and peptides in biotechnology, agriculture, and other fields are also elucidated. Furthermore, challenges and limitations in scaling up microbial production for commercial purposes are addressed. The chapter concludes by emphasizing the need for further research and development to optimize production processes, overcome scalability challenges, and fully unlock the potential of microbial systems in amino acid and peptide production. Within this captivating field lies substantial promise for various industries.

Abstract

Amino acids and peptides are essential components in many industries, including biotechnology, agriculture, and medicine. Due to its effectiveness and scalability, microbial synthesis of amino acids and peptides has become a potential strategy. This chapter offers a comprehensive summary of microbial metabolism, manufacturing techniques, recent developments, production issues, and future prospects of amino acids and peptides. The complex enzymatic mechanisms and pathways involved in microbial amino acid metabolism are explored, highlighting the importance of carbon and nitrogen supplies and the key enzymes and biosynthesis pathways. Various microbial species are compared for amino acid production, including fermentation and biotransformation processes. The benefits and drawbacks of microbial amino acid synthesis are examined. Additionally, microbial peptide synthesis is investigated, covering species and production methods such as fermentation and solid-state fermentation and discussing the advantages and limitations. The book chapter also reviews the recent advancements in metabolic engineering, synthetic biology, and genetic engineering that have enhanced amino acid and peptide production by microbial strains. The diverse applications of amino acids and peptides in biotechnology, agriculture, and other fields are also elucidated. Furthermore, challenges and limitations in scaling up microbial production for commercial purposes are addressed. The chapter concludes by emphasizing the need for further research and development to optimize production processes, overcome scalability challenges, and fully unlock the potential of microbial systems in amino acid and peptide production. Within this captivating field lies substantial promise for various industries.

Kapitel in diesem Buch

  1. Frontmatter I
  2. Contents V
  3. List of contributing authors IX
  4. Chapter 1 An introduction to biorational pest control agents 1
  5. Chapter 2 Global current scenario and future prospectus of biorationals 23
  6. Chapter 3 Biorational pest management: potentials, unintended consequences, and future concerns 47
  7. Chapter 4 Role of insect growth regulators in insect/pest control 77
  8. Chapter 5 Chemistry of sex pheromones and their role in integrated pest management 95
  9. Chapter 6 Semiochemicals and other insect communication signals for controlling insect pest 107
  10. Chapter 7 Role of phytoalexins in plant disease resistance 127
  11. Chapter 8 Microbial pesticides for plant protection 141
  12. Chapter 9 Entomopathogenic fungi as biological control agents 181
  13. Chapter 10 Pesticides of plant origin: botanicals 199
  14. Chapter 11 Plant essential oils: a source of eco-friendly pesticides 221
  15. Chapter 12 Plant oleoresins as source of environment-friendly pesticides 237
  16. Chapter 13 The rise of plant-based nematicides: a sustainable solution for crop protection 261
  17. Chapter 14 Biorationals: global situation and future possibilities 281
  18. Chapter 15 Microbial production of amino acids and peptides 295
  19. Chapter 16 Essential oils as biorational insecticides 335
  20. Chapter 17 Bioherbicides for integrated weed management 355
  21. Chapter 18 Dilemma hovers over the rationality of biorational insecticides: their unintended effects and consequences 373
  22. Index 401
https://doi.org/10.1515/9783111204819-015

Kapitel in diesem Buch

  1. Frontmatter I
  2. Contents V
  3. List of contributing authors IX
  4. Chapter 1 An introduction to biorational pest control agents 1
  5. Chapter 2 Global current scenario and future prospectus of biorationals 23
  6. Chapter 3 Biorational pest management: potentials, unintended consequences, and future concerns 47
  7. Chapter 4 Role of insect growth regulators in insect/pest control 77
  8. Chapter 5 Chemistry of sex pheromones and their role in integrated pest management 95
  9. Chapter 6 Semiochemicals and other insect communication signals for controlling insect pest 107
  10. Chapter 7 Role of phytoalexins in plant disease resistance 127
  11. Chapter 8 Microbial pesticides for plant protection 141
  12. Chapter 9 Entomopathogenic fungi as biological control agents 181
  13. Chapter 10 Pesticides of plant origin: botanicals 199
  14. Chapter 11 Plant essential oils: a source of eco-friendly pesticides 221
  15. Chapter 12 Plant oleoresins as source of environment-friendly pesticides 237
  16. Chapter 13 The rise of plant-based nematicides: a sustainable solution for crop protection 261
  17. Chapter 14 Biorationals: global situation and future possibilities 281
  18. Chapter 15 Microbial production of amino acids and peptides 295
  19. Chapter 16 Essential oils as biorational insecticides 335
  20. Chapter 17 Bioherbicides for integrated weed management 355
  21. Chapter 18 Dilemma hovers over the rationality of biorational insecticides: their unintended effects and consequences 373
  22. Index 401
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Heruntergeladen am 20.9.2025 von https://www.degruyterbrill.com/document/doi/10.1515/9783111204819-015/html
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