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Remote magnetically controlled drug release from electrospun composite nanofibers: design of a smart platform for therapy of psoriasis

  • Natália Babincová , Oldřich Jirsák , Melánia Babincová ORCID logo EMAIL logo , Peter Babinec ORCID logo and Mária Šimaljaková
Published/Copyright: May 13, 2020
Zeitschrift für Naturforschung A
From the journal Zeitschrift für Naturforschung A Volume 75 Issue 7

Abstract

An efficient method for the large-scale fabrication of composite polyvinyl alcohol polymer nano fibers loaded with magnetic nanoparticles and methotrexate is reported in this study. We have demonstrated that nonwoven textile formed by needleless electro spinning is effective in immobilization and triggered the release of drugs, which is achieved by an alternating magnetic field induced heating of magnetic nanoparticles. This smart stimuli-responsive release ability, biocompatibility, and ultra-lightweight property render enormous potential for this electrospun nano fiber mat to be used as an anti-psoriatic drugs release platform, which may have far-reaching applications in dermatology.

Keywords: composite materials; drug release; electrospinning; nanoparticles; nanofibers
Corresponding author: Melánia Babincová, Department of Nuclear Physics and Biophysics, Faculty of Mathematics, Physics and Informatics, Comenius University, Mlynská dolina F1, 842 48, Bratislava, Slovak Republic, E-mail:

Funding source: Agentúra na Podporu Výskumu a Vývoja

Award Identifier / Grant number: 16-0600

Funding source: Vedecká Grantová Agentúra MŠVVaŠ SR a SAV

Award Identifier / Grant number: 1/0810/18

Acknowledgement

This work was supported by Slovak Research and Development Agency APVV project No. 16-0600, and Slovak Grant Agency VEGA project No. 1/0810/18.

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Received: 2020-03-25
Accepted: 2020-04-10
Published Online: 2020-05-13
Published in Print: 2020-07-28

© 2020 Walter de Gruyter GmbH, Berlin/Boston

Articles in the same Issue

  1. Frontmatter
  2. General
  3. Remote magnetically controlled drug release from electrospun composite nanofibers: design of a smart platform for therapy of psoriasis
  4. Dynamical Systems & Nonlinear Phenomena
  5. A modified simple chaotic hyperjerk circuit: coexisting bubbles of bifurcation and mixed-mode bursting oscillations
  6. Dynamics of a discrete-time system with Z-type control
  7. Dynamic response of axially loaded end-bearing rectangular closed diaphragm walls
  8. Hydrodynamics
  9. Admissibility conditions for Riemann data in shallow water theory
  10. Numerical study on the rotating electro-osmotic flow of third grade fluid with slip boundary condition
  11. Solid State Physics & Materials Science
  12. Ultrasonic study of Si-oil based magneto-rheological fluid
  13. Electromagnetic propagation characteristics of one-dimensional photonic crystals with metal layers in quasi-parity-time (PT)-symmetric system
  14. Thermodynamics & Statistical Physics
  15. Combined influence of axial electron temperature and exponential plasma density ramp on the self-focusing of a chirped laser in plasma
https://doi.org/10.1515/zna-2020-0087
Keywords for this article
composite materials; drug release; electrospinning; nanoparticles; nanofibers

Articles in the same Issue

  1. Frontmatter
  2. General
  3. Remote magnetically controlled drug release from electrospun composite nanofibers: design of a smart platform for therapy of psoriasis
  4. Dynamical Systems & Nonlinear Phenomena
  5. A modified simple chaotic hyperjerk circuit: coexisting bubbles of bifurcation and mixed-mode bursting oscillations
  6. Dynamics of a discrete-time system with Z-type control
  7. Dynamic response of axially loaded end-bearing rectangular closed diaphragm walls
  8. Hydrodynamics
  9. Admissibility conditions for Riemann data in shallow water theory
  10. Numerical study on the rotating electro-osmotic flow of third grade fluid with slip boundary condition
  11. Solid State Physics & Materials Science
  12. Ultrasonic study of Si-oil based magneto-rheological fluid
  13. Electromagnetic propagation characteristics of one-dimensional photonic crystals with metal layers in quasi-parity-time (PT)-symmetric system
  14. Thermodynamics & Statistical Physics
  15. Combined influence of axial electron temperature and exponential plasma density ramp on the self-focusing of a chirped laser in plasma
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