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Infections causing cancers: world burden and potential for prevention

  • Catherine de Martel EMAIL logo , Martyn Plummer und Silvia Franceschi
Veröffentlicht/Copyright: 9. Januar 2015

Abstract

Infections with viruses, bacteria, and parasites have long been identified as strong risk factors for specific cancers (Table 1) (IARC, 2012). Worldwide, about 2.1 million of the total of 12.7 million cancer cases that occurred in 2008 (16.5% of all cases) are attributable to infections (de Martel et al., 2012). This fraction varies 10-fold by region; it is lowest in North America, Australia, and New Zealand (≤ 5%) and highest in sub-Saharan Africa (>30%) (Figure 1). Helicobacter pylori, hepatitis B and C viruses, and human papillomaviruses are responsible for 1.9 million cancer cases globally, mainly encompassing gastric, liver, and cervical cancer, respectively.

Einleitung

Der Beitrag gibt einen Überblick über Infektionen, die die Entstehung bestimmter Krebsarten verursachen können und zeigt Möglichkeiten für die Prävention auf. Dabei werden Helicobacter pylori (H. pylori), Hepatitis B und C (HBV and HCV), Epstein–Barr Virus (EBV), Humane Papillomaviren (HPV) und HIV angesprochen.

References

de Martel et al., 2012 de Martel C., Ferlay J., Franceschi S., Vignat J., Bray F., Forman D., Plummer M. "Global burden of cancers attributable to infections in 2008: a review and synthetic analysis" Lancet Oncol, vol. 13, 2012, p. 60761510.1016/S1470-2045(12)70137-7. Suche in Google Scholar

IARC, 2012 IARC"Monographs on the Evaluation of Carcinogenic Risks to Humans Volume 100B: A Review of Human Carcinogens: Biological Agents" IARC Monogr Eval Carcinog Risks Hum, 2012 International Agency for Research on Cancer: Lyon. Suche in Google Scholar

Plummer et al., 2014 Plummer M., Franceschi S., Vignat J., Forman D., de Martel C. "Global burden of gastric cancer attributable to Helicobacter pylori" Int J Cancer, 2014[Epub ahead of print]. Suche in Google Scholar

Published Online: 2015-1-9
Published in Print: 2014-10-1

© 2015 by Walter de Gruyter Berlin/Boston

Heruntergeladen am 12.10.2025 von https://www.degruyterbrill.com/document/doi/10.1016/j.phf.2014.07.003/html
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