Volume 41, Issue 2

Conventional treatment modes like chemotherapy, thermal and radiations aimed at cancerous cells eradication are marked by destruction pointing the employment of nanomaterials as sustainable and auspicious materials for saving human lives. Cancer has been deemed as the second leading cause of death on a global scale. Nanomaterials employment in cancer treatment is based on the utilization of their inherent physicochemical characteristics in addition to their modification for using as nano-carriers and nano-vehicles eluted with anti-cancer drugs. Current work has reviewed the significant role of different types of nanomaterials in cancer therapeutics and diagnostics in a systematic way. Compilation of review has been done by analyzing voluminous investigations employing ERIC, MEDLINE, NHS Evidence and Web of Science databases. Search engines used were Google scholar, Jstore and PubMed. Current review is suggestive of the remarkable performance of nanomaterials making them candidates for cancer treatment for substitution of destructive treatment modes through investigation of their physicochemical characteristics, utilization outputs and long term impacts in patients.

Organometallic complexes of neodymium have unique coordinating ability to form both micro and macromolecules as well as metal-based polymers. These complexes have been reported in different fields and play a tremendous role in luminescence, catalytic, biological and magnetic applications. So, the current study will comprise all possible routes for the synthesis of organometallic complexes of neodymium. Neodymium complexes have been synthesized of single, double, triple and tetra linkages with H, C, N, O as well as S, B, and X. The detailed synthetic routes have been classified into four categories but in brief, neodymium forms complexes by reacting metal chloride, nitrate or oxide (hydrated or dehydrated) as precursor along with appropriate ligand. Most applied solvents for neodymium complexes were Toluene and THF. These complexes required a range of temperature based on the nature of complexes as well as linkages. The authors have surveyed the research work published through 2011–2020 and provide a comprehensive overview to understand the synthetic routes of organometallic complexes of neodymium.