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Preparation of salt microparticles via the anti-solvent recrystallization process

  • Wei Huang , Shuai Pan , Yanghua Liu , Qingmei Yu and Ruijiang Liu
Published/Copyright: January 31, 2020
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International Journal of Materials Research
From the journal International Journal of Materials Research Volume 111 Issue 2

Abstract

The anti-solvent recrystallization process for the preparation of salt microparticles is introduced. The micron size of salt particles was confirmed by scanning electron microscopy. The preparation conditions such as the antisolvent types, dripping acceleration, stirring time, the volume ratio of antisolvent and solvent, and adding sequence of solvent were optimized. The experimental results indicated that these preparation conditions were as follows: The saturated salt solution was added into absolute alcohol at a dripping acceleration of 10 mL · min−1, a stirring time duration of 30 min, and an antisolvent and solvent volume ratio of 4 : 1. Salt microparticles with an average diameter of about 6.3 μm, uniform size distribution and better crystallization were obtained under the above optimization conditions.

Keywords: Salt microparticles; Anti-solvent recrystallization; Optimization
∗ Correspondence address, Prof. Ruijiang Liu, Jiangsu University, School of Pharmacy, Zhenjiang 212013, P.R. China. Fax: +86-511-85038201, E-mail:

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Received: 2019-04-15
Accepted: 2019-08-13
Published Online: 2020-01-31
Published in Print: 2020-02-12

© 2020, Carl Hanser Verlag, München

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https://doi.org/10.3139/146.111862
Keywords for this article
Salt microparticles; Anti-solvent recrystallization; Optimization

Articles in the same Issue

  1. Contents
  2. Contents
  3. Original Contributions
  4. Solidification processes of as-cast alloys and phase equilibria at 1 300 °C of the Nb–Si–V ternary system
  5. Compressive properties and energy absorption response of cBN added Al composite foams
  6. Deformation characteristics of Cu-30 % Zn alloy subjected to dynamic equal channel angular pressing (DECAP)
  7. Stress-based forming limit diagrams (SFLD) considering strain rate effect and ductile damage phenomenon
  8. Processing and properties of ultrafine-grained Mg-3Al-1Zn magnesium alloy microtubes fabricated via isothermal hot microforming of SPD processed precursors
  9. The effect of in-situ formed TiB2 particles on microstructural and mechanical properties of laser melted copper alloy
  10. Nanoindentation study on Al86Ni8Y6 glassy alloy synthesized via mechanical alloying and spark plasma sintering
  11. Synthesis of nanosized cadmium ferrite and assaying its magnetic and dielectric properties by analytical and physical techniques
  12. BN nanosheet modified SnO materials for enhancing photocatalytic properties
  13. Preparation of salt microparticles via the anti-solvent recrystallization process
  14. Short Communications
  15. CVD grown graphene on commercial and electroplated Cu substrates: Raman spectroscopy analysis
  16. DGM News
  17. DGM News
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