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Mixed-ligand complexes of boric acid with organic biomolecules

  • Dursun Köse EMAIL logo and Birgül Zümreoglu-Karan
Published/Copyright: November 16, 2011
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Chemical Papers
From the journal Chemical Papers Volume 66 Issue 1

Abstract

Boric acid forms meta-stable complexes with biomolecules like amino and hydroxy acids and stable complexes with the diol group containing carbohydrates, vitamins, and nucleotides, yielding mono-chelate (1: 1 complex) or bis-chelate (1: 2 complex) structures with negatively charged tetrahedral borate anions. Here we report water-soluble, bio-available mixed-ligand boron adducts for potential nutritional and/or pharmaceutical applications. The complexes were prepared by complete esterification of boric acid with a number of acyclic- and cyclic hydroxy-functionalized biomolecules employing sodium as the counter ion. Structural and thermal properties of the complexes were investigated using chemical analysis, 11B NMR, FTIR, and TGA-DTA techniques. Complexes containing salicylic acid as one of the ligands displayed higher thermal and hydrolytic stabilities.

Keywords: boric acid complexes; boron adducts; borate esters; 11B NMR; mixed ligand complexes

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Published Online: 2011-11-16
Published in Print: 2012-1-1

© 2011 Institute of Chemistry, Slovak Academy of Sciences

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https://doi.org/10.2478/s11696-011-0108-0
Keywords for this article
boric acid complexes; boron adducts; borate esters; 11B NMR; mixed ligand complexes

Articles in the same Issue

  1. Layered double hydroxides — multifunctional nanomaterials
  2. A novel reagent for spectroscopic determination of Mo(VI)
  3. Influence of chemical composition of nanocrystalline iron’s surface on the rates of two parallel reactions: nitriding and catalytic decomposition of ammonia
  4. Application of 2-(octylsulphanyl)benzoic acid as Pb2+ selective ionophore in hybrid membrane system
  5. Additive-assisted Rupe rearrangement of 1-ethynylcyclohexan-1-ol in near-critical water
  6. Treatment of acidic palm oil for fatty acid methyl esters production
  7. Synthesis, structure, and luminescent properties of two novel polynuclear complexes of 1,3-di(pyridin-2-yl)propane-1,3-dione
  8. Mixed-ligand complexes of boric acid with organic biomolecules
  9. Ultrasound-assisted rapid synthesis of β-aminoketones with direct-type catalytic Mannich reaction using bismuth(III) triflate in aqueous media at room temperature
  10. Design, synthesis, preliminary pharmacological evaluation, and docking studies of pyrazoline derivatives
  11. One-pot synthesis and luminescent spectra of 3-allyl substituted quinazoline-2,4-dione derivatives as allyl capping agents
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