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Polymer interfaces used in electrochemical DNA-based biosensors

  • Júlia Galandová EMAIL logo and Ján Labuda
Published/Copyright: November 20, 2008
Become an author with De Gruyter Brill

Abstract

Nowadays DNA-based biosensors represent powerful tools for the study of DNA sequence, DNA chemical interactions and damage. Among them, biosensors with an electrochemical signal transducer play the most important role. The performance of a biosensor strongly depends on the method of a biorecognition element being attached to the electrode. This review refers to polymer materials being used to create a DNA-electrode interface. The main terminology is given in Introduction followed by a description of polymers and polymer-based nanocomposites and their electrochemical properties. A comprehensive table reports examples of the electrochemical detection of DNA immobilized on the polymer matrix. Finally, a short survey is given.

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Published Online: 2008-11-20
Published in Print: 2009-2-1

© 2008 Institute of Chemistry, Slovak Academy of Sciences

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