Reactions of trans-[PtX2(pic)2] (Pic = γ-PICOLINE, X = Cl−, NO3 −) with N-acetyl-l-cysteine and glutathione
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,
Abstract
The reactions of trans-[PtX2(pic)2] (pic = γ-picoline, X = Cl−, NO3 −) with N-acetyl-l-cysteine (acSH) and glutathione (GSH) were monitored and followed by 1H and 195Pt NMR. In the reaction of trans-[Pt(pic)2(D2O)2](NO3)2 with acSH, in the 195Pt NMR spectra, the most intense peak observed was trans-[Pt(pic)2(acS)}2(µ-acS)]+ (3). The intermediate product which was not clearly seen in the spectra was formulated as trans-[Pt (pic)2(acS)(D2O)]+ (2), with the weaker peak one as trans-[Pt(pic)2(acS)2] (1). With GSH, the main product observed was trans-[Pt(pic)2(GS)2] (4), while the intermediate product was not observed during this study. In the reactions of trans-[PtCl2(pic)2] with acSH, besides complexes 1 and 3 formed, the formation of trans-[Pt(pic)2Cl(acS)] (6) was also observed in the NMR spectra, while when it was reacted with GSH, followed a similar course to that of with acSH, but more slowly.
Acknowledgments
We thank to Ms. L. Lambert (University of Queensland, Australia) for her assistance in N.M.R. experimentation.
References
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- Evaluation of in vitro antioxidant activities, total phenolic and elemental contents of common herbs and spices (Moringa oleifera leaves, Allium sativum (Garlic) and Momordica charantia (ejinrin) leaves) in South-West Nigeria
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- Reactions of trans-[PtX2(pic)2] (Pic = γ-PICOLINE, X = Cl−, NO3 −) with N-acetyl-l-cysteine and glutathione
Articles in the same Issue
- Frontmatter
- In this issue
- Special topic papers
- An innovative method using data acquisition and MATLAB for the electrochemical oxidation of formalin and the conversion of the oxidized products into a sound signal
- Evaluation of in vitro antioxidant activities, total phenolic and elemental contents of common herbs and spices (Moringa oleifera leaves, Allium sativum (Garlic) and Momordica charantia (ejinrin) leaves) in South-West Nigeria
- Management of biofilm-associated infections in diabetic wounds – from bench to bedside
- Biodegradation of naphthalene using Kocuria rosea isolated from a Sawmill in Ikenne, Southwestern Nigeria
- Production of green hydrogen through PEM water electrolysis
- Synthesis of potash alum from waste aluminum cans for the purification of river water
- Current advances in QuEChERS extraction of mycotoxins in various food and feed matrices
- Biological potentials of Landolphia owariensis leaf methanolic extract against pathogenic fungi isolates from different Dioscorea species
- Nitrogen leaching mitigation by tithonia biochar (Tithochar) in urea fertilizer treated sandy soil
- Phytochemicals as potential active principal components for formulation of alternative antifungal remedies against Trichophyton spp.: a systematic review
- A review on the green chemistry perspective of multipurpose use of cow urine
- Reactions of trans-[PtX2(pic)2] (Pic = γ-PICOLINE, X = Cl−, NO3 −) with N-acetyl-l-cysteine and glutathione
