Abstract
In this age of emergent resistance to antimicrobial agents, pathogenic fungi are not an exception. Diverse strategies have been implemented to curb rampant fungal infections including screening new drugs and stewardship programs. A plethora of recent studies have proved that phytochemicals are efficacious against pathogenic fungi and have potent antifungal activity. This review examines the use of phytochemicals as possible alternative antifungal agents against dermatophytes particularly Trichophyton spp. Literature search was done using three search engines namely Google Scholar, PubMed and Science Direct limited to the year 2019–2023 only. A total of 30 articles were included and 48 plant extracts were evaluated. The major phytochemicals that proved to be potent antifungals both in vitro and in vivo were terpenoids and phenolics. The antifungal potential of phyto-compounds was significantly elevated by incarnation with nanotechnology. Although much has been done in screening of herbal extracts as possible antifungal agents huge gaps still exist on full characterization of all active herbal extracts with antifungal potential especially against resistant strains, together with their mechanism of action, formulation of pharmaceutical dosage forms and clinical trials.
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Articles in the same Issue
- Frontmatter
- In this issue
- Special topic papers
- An innovative method using data acquisition and MATLAB for the electrochemical oxidation of formalin and the conversion of the oxidized products into a sound signal
- Evaluation of in vitro antioxidant activities, total phenolic and elemental contents of common herbs and spices (Moringa oleifera leaves, Allium sativum (Garlic) and Momordica charantia (ejinrin) leaves) in South-West Nigeria
- Management of biofilm-associated infections in diabetic wounds – from bench to bedside
- Biodegradation of naphthalene using Kocuria rosea isolated from a Sawmill in Ikenne, Southwestern Nigeria
- Production of green hydrogen through PEM water electrolysis
- Synthesis of potash alum from waste aluminum cans for the purification of river water
- Current advances in QuEChERS extraction of mycotoxins in various food and feed matrices
- Biological potentials of Landolphia owariensis leaf methanolic extract against pathogenic fungi isolates from different Dioscorea species
- Nitrogen leaching mitigation by tithonia biochar (Tithochar) in urea fertilizer treated sandy soil
- Phytochemicals as potential active principal components for formulation of alternative antifungal remedies against Trichophyton spp.: a systematic review
- A review on the green chemistry perspective of multipurpose use of cow urine
- Reactions of trans-[PtX2(pic)2] (Pic = γ-PICOLINE, X = Cl−, NO3 −) with N-acetyl-l-cysteine and glutathione
Articles in the same Issue
- Frontmatter
- In this issue
- Special topic papers
- An innovative method using data acquisition and MATLAB for the electrochemical oxidation of formalin and the conversion of the oxidized products into a sound signal
- Evaluation of in vitro antioxidant activities, total phenolic and elemental contents of common herbs and spices (Moringa oleifera leaves, Allium sativum (Garlic) and Momordica charantia (ejinrin) leaves) in South-West Nigeria
- Management of biofilm-associated infections in diabetic wounds – from bench to bedside
- Biodegradation of naphthalene using Kocuria rosea isolated from a Sawmill in Ikenne, Southwestern Nigeria
- Production of green hydrogen through PEM water electrolysis
- Synthesis of potash alum from waste aluminum cans for the purification of river water
- Current advances in QuEChERS extraction of mycotoxins in various food and feed matrices
- Biological potentials of Landolphia owariensis leaf methanolic extract against pathogenic fungi isolates from different Dioscorea species
- Nitrogen leaching mitigation by tithonia biochar (Tithochar) in urea fertilizer treated sandy soil
- Phytochemicals as potential active principal components for formulation of alternative antifungal remedies against Trichophyton spp.: a systematic review
- A review on the green chemistry perspective of multipurpose use of cow urine
- Reactions of trans-[PtX2(pic)2] (Pic = γ-PICOLINE, X = Cl−, NO3 −) with N-acetyl-l-cysteine and glutathione