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Risk factors for postpartum hypertension in women with twin pregnancies

  • Mamoru Morikawa EMAIL logo , Kazutoshi Cho , Takashi Yamada , Takahiro Yamada , Rina Akaishi , Takahiro Koyama , Masamitsu Takeda , Ryutaro Nishida and Hisanori Minakami
Published/Copyright: October 24, 2011
Journal of Perinatal Medicine
From the journal Volume 40 Issue 2

Abstract

Objective: Which physical findings and blood parameters predict postpartum hypertension remain to be studied in women with twin pregnancies.

Methods: The antenatal systolic and diastolic blood pressures (SBP and DBP, respectively), and 16 laboratory variables were investigated in 150 normotensive women who gave birth to twins.

Results: When the median values of the 18 continuous variables were used as cut-off values, an SBP>120 mm Hg (relative risk [95% confidence interval], 2.81 [1.94–4.08]), a DBP>70 mm Hg (2.42 [1.68–3.49]), an aspartate aminotransferase level>18 U/L (2.22 [1.55–3.19]), and a uric acid level>5.3 mg/dL (1.68 [1.20–2.36]) were independent risk factors for postpartum hypertension.

Conclusions: Antenatal blood pressure measurements and a laboratory work-up may be useful clinically for predicting postpartum hypertension in women with twin pregnancies.


Corresponding author: Mamoru Morikawa, MD, PhD Department of Obstetrics Hokkaido University Graduate School of Medicine Kita-ku N15 W7 Sapporo 060-8638 Japan Tel.: +81-11-706-5941 Fax: +81-11-706-7711

Received: 2011-5-30
Revised: 2011-7-20
Accepted: 2011-8-26
Published Online: 2011-10-24
Published in Print: 2012-02-01

©2012 by Walter de Gruyter Berlin Boston

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