Article
Licensed
Unlicensed
Requires Authentication
In utero exposure to Ureaplasma spp. is associated with increased rate of bronchopulmonary dysplasia and intraventricular hemorrhage in preterm infants
-
David C. Kasper
,
Thomas P. Mechtler
Published/Copyright:
May 9, 2011
Abstract
Aims: We determined the association between short-term neonatal morbidities, such as bronchopulmonary dysplasia (BPD) and intraventricular hemorrhage (IVH), and Ureaplasma spp. in amniotic fluid, placental and amniotic mem-brane of preterm infants.
Methods: This study enrolled 257 patients who were born by cesarean section at <34 weeks’ gestation. Patients were divided into two groups according to detection of Ureaplasma spp. by culture-based and/or polymerase chain reaction (PCR) techniques.
Results: Significant differences were observed between both groups for all IVH (P=0.032) and IVH grades III or IV (P=0.013), as wells as for BPD [odds ratio (OR) 5.46, 95% confidence interval (CI) 2.02–14.77], oxygen requirement at 28 days postnatal age (OR 1.93, 95% CI 1.00–3.70), and for death between 28 days and 36 postmenstrual weeks or BPD (OR 4.20, 95% CI 1.77–9.96). Ureaplasma spp. was a significant predictor (P<0.001) of BPD after correcting for birth weight (P=0.003) and positive pressure ventilation (P=0.001).
Conclusions: In our study population Ureaplasma spp. was associated with BPD and IVH in preterm infants even after adjustment for multiple risk factors.
Keywords: Bronchopulmonary dysplasia; intrauterine infection; intraventricular hemorrhage; preterm infant; Ureaplasma spp
Received: 2010-8-23
Revised: 2010-11-25
Accepted: 2010-12-9
Published Online: 2011-05-09
Published Online: 2011-04-29
Published in Print: 2011-05-01
©2011 by Walter de Gruyter Berlin New York
You are currently not able to access this content.
You are currently not able to access this content.
Articles in the same Issue
- Publisher’s Note
- Publisher’s Note
- EDITORIAL
- Problems in prevention of preterm birth – regrettable contradictions
- REVIEW ARTICLES
- Listeriosis in human pregnancy: a systematic review
- Prevention of prematurity by single embryo transfer
- ORIGINAL ARTICLES - OBSTETRICS
- Effect of prior cesarean delivery on neonatal outcomes
- Amniotic lamellar body counts can predict the occurrence of respiratory distress syndrome as well as transient tachypnea of the newborn (TTN)
- Spectrum of cardiovascular findings during pregnancy and parturition at a tertiary referral center
- Risk groups and maternal-neonatal complications of preeclampsia – Current results from the national German Perinatal Quality Registry
- miRNA expression profiling in formalin-fixed and paraffin-embedded placental tissue samples from pregnancies with severe preeclampsia
- Genetic polymorphisms of killer cell immunoglobulin-like receptor 3DL2 in preeclampsia
- Addressing concerns about cisplatin application during pregnancy
- Retinol-binding protein-4 is decreased in patients with preeclampsia in comparison with normal pregnant women
- Somatic classification of neonates based on birth weight, length, and head circumference: quantification of the effects of maternal BMI and smoking
- Prediction of successful labor induction by evaluation of maternal symptoms at an early stage of the misoprostol induction protocol
- ORIGINAL ARTICLES - FETUS
- Increased nuchal translucency is associated with large for gestational age neonates in singleton pregnancies
- ORIGINAL ARTICLES - NEWBORN
- Predicting mortality in infants with persistent pulmonary hypertension of the newborn with the Score for Neonatal Acute Physiology-Version II (SNAP-II) in Thai neonates
- Neonatal outcome of preterm discordant twins
- Effects of delayed umbilical cord clamping on peripheral blood hematopoietic stem cells in premature neonates
- In utero exposure to Ureaplasma spp. is associated with increased rate of bronchopulmonary dysplasia and intraventricular hemorrhage in preterm infants
- Does prenatal antibiotic therapy compromise the diagnosis of early-onset infection and management of the neonate?
- SNAPPE-II application in newborns with very low birth weight: evaluation of adverse outcomes in severe placental dysfunction
- SHORT COMMUNICATION
- Lamellar bodies: platelet channel particles as predictors of respiratory distress syndrome (RDS) and of transient tachypnea of the newborn
- Intrahepatic and adrenal hemorrhage as a rare cause of neonatal anemia
- Subcutaneous fat distribution in small for gestational age newborns
- Calendar
- Congress Calendar
Keywords for this article
Bronchopulmonary dysplasia;
intrauterine infection;
intraventricular hemorrhage;
preterm infant;
Ureaplasma spp
Articles in the same Issue
- Publisher’s Note
- Publisher’s Note
- EDITORIAL
- Problems in prevention of preterm birth – regrettable contradictions
- REVIEW ARTICLES
- Listeriosis in human pregnancy: a systematic review
- Prevention of prematurity by single embryo transfer
- ORIGINAL ARTICLES - OBSTETRICS
- Effect of prior cesarean delivery on neonatal outcomes
- Amniotic lamellar body counts can predict the occurrence of respiratory distress syndrome as well as transient tachypnea of the newborn (TTN)
- Spectrum of cardiovascular findings during pregnancy and parturition at a tertiary referral center
- Risk groups and maternal-neonatal complications of preeclampsia – Current results from the national German Perinatal Quality Registry
- miRNA expression profiling in formalin-fixed and paraffin-embedded placental tissue samples from pregnancies with severe preeclampsia
- Genetic polymorphisms of killer cell immunoglobulin-like receptor 3DL2 in preeclampsia
- Addressing concerns about cisplatin application during pregnancy
- Retinol-binding protein-4 is decreased in patients with preeclampsia in comparison with normal pregnant women
- Somatic classification of neonates based on birth weight, length, and head circumference: quantification of the effects of maternal BMI and smoking
- Prediction of successful labor induction by evaluation of maternal symptoms at an early stage of the misoprostol induction protocol
- ORIGINAL ARTICLES - FETUS
- Increased nuchal translucency is associated with large for gestational age neonates in singleton pregnancies
- ORIGINAL ARTICLES - NEWBORN
- Predicting mortality in infants with persistent pulmonary hypertension of the newborn with the Score for Neonatal Acute Physiology-Version II (SNAP-II) in Thai neonates
- Neonatal outcome of preterm discordant twins
- Effects of delayed umbilical cord clamping on peripheral blood hematopoietic stem cells in premature neonates
- In utero exposure to Ureaplasma spp. is associated with increased rate of bronchopulmonary dysplasia and intraventricular hemorrhage in preterm infants
- Does prenatal antibiotic therapy compromise the diagnosis of early-onset infection and management of the neonate?
- SNAPPE-II application in newborns with very low birth weight: evaluation of adverse outcomes in severe placental dysfunction
- SHORT COMMUNICATION
- Lamellar bodies: platelet channel particles as predictors of respiratory distress syndrome (RDS) and of transient tachypnea of the newborn
- Intrahepatic and adrenal hemorrhage as a rare cause of neonatal anemia
- Subcutaneous fat distribution in small for gestational age newborns
- Calendar
- Congress Calendar
