Severe maternal thrombocytopenia and prenatal invasive procedures: still a grey zone
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Elena D’Alberti
,
Roberto Brunelli
,
Paola Galoppi
,
Cristina Santoro
Abstract
Management of severe thrombocytopenia, particularly of ITP, in pregnancy is mainly based on expert consensus and clinical experience while there are no clear indications about the minimum platelet count requested for prenatal diagnosis invasive procedures. Since the lack of specific recommendations we reported our clinical management of a patient suffering from severe thrombocytopenia, undergoing amniocentesis. Due to the anecdotic possibility of maternal and fetal bleeding in case of severe thrombocytopenia, prophylaxis with IVIG or even corticosteroids could be considered as a safer strategy to prevent post-procedural adverse outcomes.
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Research funding: None declared.
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Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.
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Competing interests: Authors state no conflict of interest.
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Informed consent: Informed consent was obtained from the study patient.
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Ethical approval: Not applicable.
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© 2023 Walter de Gruyter GmbH, Berlin/Boston
Articles in the same Issue
- Frontmatter
- Reviews
- Covid-19 vaccination and pregnancy: a systematic review of maternal and neonatal outcomes
- Improvised bubble continuous positive airway pressure ventilation use in neonates in resource-limited settings: a systematic review and meta-analysis
- Opinion Papers
- Anger: an underappreciated destructive force in healthcare
- Severe maternal thrombocytopenia and prenatal invasive procedures: still a grey zone
- Commentary
- The care of the magic of life before and after its beginning
- Original Articles – Obstetrics
- The impact of trimester of COVID-19 infection on pregnancy outcomes after recovery
- Adverse outcomes and maternal complications in pregnant women with severe-critical COVID-19: a tertiary center experience
- Are bacteria, fungi, and archaea present in the midtrimester amniotic fluid?
- Bioavailability of the tumor necrosis factor alpha/regulated on activation, normal T cell expressed and secreted (RANTES) biosystem inside the gestational sac during the pre-immune stages of embryo development
- The role of the soluble fms-like tyrosine kinase-1/placental growth factor (sFlt-1/PIGF) – ratio in clinical practice in obstetrics: diagnostic and prognostic value
- Prenatal diagnosis of non-mosaic sex chromosome abnormalities: a 10-year experience from a tertiary referral center
- Prediction of lung maturity through quantitative ultrasound analysis of fetal lung texture in women with diabetes during pregnancy
- Evaluation of an artificial intelligent algorithm (Heartassist™) to automatically assess the quality of second trimester cardiac views: a prospective study
- Original Article – Fetus
- Fetal brain activity and the free energy principle
- Predictive value of ultrasound in prenatal diagnosis of hypospadias: hints for accurate diagnosis
- The effect of maternal diabetes on the expression of gamma-aminobutyric acid and metabotropic glutamate receptors in male newborn rats’ inferior colliculi
- Original Articles – Neonates
- Respiratory function monitoring during early resuscitation and prediction of outcomes in prematurely born infants
- Quality improvement sustainability to decrease utilization drift for therapeutic hypothermia in the NICU
- Short Communication
- Use of a pocket-device point-of-care ultrasound to assess cervical dilation in labor: correlation and patient experience
- Letters to the Editor
- Correspondence on “COVID-19 vaccination and pregnancy”
- Response to the letter to the editor regarding “Covid-19 vaccination and pregnancy: a systematic review of maternal and neonatal outcomes”
Articles in the same Issue
- Frontmatter
- Reviews
- Covid-19 vaccination and pregnancy: a systematic review of maternal and neonatal outcomes
- Improvised bubble continuous positive airway pressure ventilation use in neonates in resource-limited settings: a systematic review and meta-analysis
- Opinion Papers
- Anger: an underappreciated destructive force in healthcare
- Severe maternal thrombocytopenia and prenatal invasive procedures: still a grey zone
- Commentary
- The care of the magic of life before and after its beginning
- Original Articles – Obstetrics
- The impact of trimester of COVID-19 infection on pregnancy outcomes after recovery
- Adverse outcomes and maternal complications in pregnant women with severe-critical COVID-19: a tertiary center experience
- Are bacteria, fungi, and archaea present in the midtrimester amniotic fluid?
- Bioavailability of the tumor necrosis factor alpha/regulated on activation, normal T cell expressed and secreted (RANTES) biosystem inside the gestational sac during the pre-immune stages of embryo development
- The role of the soluble fms-like tyrosine kinase-1/placental growth factor (sFlt-1/PIGF) – ratio in clinical practice in obstetrics: diagnostic and prognostic value
- Prenatal diagnosis of non-mosaic sex chromosome abnormalities: a 10-year experience from a tertiary referral center
- Prediction of lung maturity through quantitative ultrasound analysis of fetal lung texture in women with diabetes during pregnancy
- Evaluation of an artificial intelligent algorithm (Heartassist™) to automatically assess the quality of second trimester cardiac views: a prospective study
- Original Article – Fetus
- Fetal brain activity and the free energy principle
- Predictive value of ultrasound in prenatal diagnosis of hypospadias: hints for accurate diagnosis
- The effect of maternal diabetes on the expression of gamma-aminobutyric acid and metabotropic glutamate receptors in male newborn rats’ inferior colliculi
- Original Articles – Neonates
- Respiratory function monitoring during early resuscitation and prediction of outcomes in prematurely born infants
- Quality improvement sustainability to decrease utilization drift for therapeutic hypothermia in the NICU
- Short Communication
- Use of a pocket-device point-of-care ultrasound to assess cervical dilation in labor: correlation and patient experience
- Letters to the Editor
- Correspondence on “COVID-19 vaccination and pregnancy”
- Response to the letter to the editor regarding “Covid-19 vaccination and pregnancy: a systematic review of maternal and neonatal outcomes”
