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Gastroschisis: incidence and prediction of growth restriction

  • Fadi G. Mirza EMAIL logo , Samuel T. Bauer , Anne Van der Veer und Lynn L. Simpson
Veröffentlicht/Copyright: 2. Dezember 2014
Journal of Perinatal Medicine
Aus der Zeitschrift Journal of Perinatal Medicine Band 43 Heft 5

Abstract

Aims: Fetuses with gastroschisis are at increased risk of intrauterine growth restriction (IUGR). However, there is a tendency for underestimation of fetal abdominal circumference and hence fetal weight, leading to overdiagnosis of IUGR. Our objective was to evaluate the accuracy of ultrasound for the prediction of being small for gestational age (SGA) at birth in these cases.

Methods: A retrospective study of prenatally diagnosed cases of gastroschisis was conducted at a tertiary center. Fetal weight was estimated using the formula of Hadlock. IUGR was defined as an estimated fetal weight ≤10th percentile for gestational age. SGA at the time of birth was defined as a birth weight ≤10th percentile for gestational age. The incidence of IUGR on last ultrasound and that of SGA at birth were calculated, and the precision of ultrasound in predicting SGA was determined.

Results: IUGR was reported on the last ultrasound prior to delivery in 9/25 cases (36%). Postnatally, 13/25 newborns (52%) were SGA. All sonographically suspected cases of IUGR based on the last ultrasound were SGA at birth. The positive predictive value of the last ultrasound in identifying SGA was 100%.

Conclusions: At least half of the infants affected by gastroschisis were SGA at birth. Sonographic estimation of fetal weight within 1 month of birth reliably predicted SGA in infants with gastroschisis.

Keywords: Estimated fetal weight; fetal growth restriction; gastroschisis; intrauterine growth restriction; small for gestational age
Corresponding author: Fadi G. Mirza, MD, FACOG, Department of Obstetrics and Gynecology, American University of Beirut, 3 Dag Hammarskjold Plaza, Eighth Floor, New York, NY 10017, USA, Phone: +212 305 6293, Fax: +212 342 2717, E-mail: ; Division of Maternal Fetal Medicine, Faculty of Medicine, Department of Obstetrics and Gynecology, American University of Beirut, Beirut, Lebanon; and Division of Maternal Fetal Medicine, College of Physicians and Surgeons, Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA
Source: American University of Beirut Medical Center, Beirut, Lebanon.

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The authors stated that there are no conflicts of interest regarding the publication of this article.

Received: 2014-8-22
Accepted: 2014-10-16
Published Online: 2014-12-2
Published in Print: 2015-9-1

©2015 by De Gruyter

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Risk factors for preterm birth and new approaches to its early diagnosis
  4. Review
  5. Avoiding the prenatal programming effects of glucocorticoids: are there alternative treatments for the induction of antenatal lung maturation?
  6. Original articles – Obstetrics
  7. The association of first trimester bleeding with preterm delivery
  8. Cervical sonoelastography for improving prediction of preterm birth compared with cervical length measurement and fetal fibronectin test
  9. The neuroprotective effect of magnesium sulfate in preterm fetal mice
  10. Correlation of cervical length, fetal fibronectin, phIGFBP-1, and cytokines in spontaneous preterm birth up to 14 days from sampling
  11. The unborn smoker: association between smoking during pregnancy and adverse perinatal outcomes
  12. Association of group B streptococcus colonization with early term births
  13. Association of maternal whole blood fatty acid status during the prenatal period with term birth dimensions: a cross-sectional study
  14. Predicting onset of labor from echogenicity of the cervical gland area on vaginal ultrasonography at term
  15. Disparity in post-treatment maternal circulating magnesium sulfate levels between twin and singleton gestation: Is this the missing link between plurality and adverse outcome?
  16. Original articles – Fetus
  17. Cardiovascular profile score in 44 fetuses with cervicofacial tumors
  18. First trimester tricuspid regurgitation and fetal abnormalities
  19. Gastroschisis: incidence and prediction of growth restriction
  20. Original articles – Newborn
  21. Diminished HLA-DR expression on monocyte and dendritic cell subsets indicating impairment of cellular immunity in pre-term neonates: a prospective observational analysis
  22. First- and fifth-minute Apgar scores of 0–3 and infant mortality: a population-based study in São Paulo State of Brazil
  23. Feeding the feeble: steps towards nourishing preterm infants
  24. Book review
  25. Hot topics in perinatal medicine
  26. Erratum
  27. Erratum to: Impact of the nitric oxide-donor pentaerythrityl-tetranitrate on perinatal outcome in risk pregnancies: a prospective, randomized, double-blinded trial
  28. Congress Calendar
  29. Congress Calendar
https://doi.org/10.1515/jpm-2014-0283
Schlagwörter für diesen Artikel
Estimated fetal weight; fetal growth restriction; gastroschisis; intrauterine growth restriction; small for gestational age

Artikel in diesem Heft

  1. Frontmatter
  2. Editorial
  3. Risk factors for preterm birth and new approaches to its early diagnosis
  4. Review
  5. Avoiding the prenatal programming effects of glucocorticoids: are there alternative treatments for the induction of antenatal lung maturation?
  6. Original articles – Obstetrics
  7. The association of first trimester bleeding with preterm delivery
  8. Cervical sonoelastography for improving prediction of preterm birth compared with cervical length measurement and fetal fibronectin test
  9. The neuroprotective effect of magnesium sulfate in preterm fetal mice
  10. Correlation of cervical length, fetal fibronectin, phIGFBP-1, and cytokines in spontaneous preterm birth up to 14 days from sampling
  11. The unborn smoker: association between smoking during pregnancy and adverse perinatal outcomes
  12. Association of group B streptococcus colonization with early term births
  13. Association of maternal whole blood fatty acid status during the prenatal period with term birth dimensions: a cross-sectional study
  14. Predicting onset of labor from echogenicity of the cervical gland area on vaginal ultrasonography at term
  15. Disparity in post-treatment maternal circulating magnesium sulfate levels between twin and singleton gestation: Is this the missing link between plurality and adverse outcome?
  16. Original articles – Fetus
  17. Cardiovascular profile score in 44 fetuses with cervicofacial tumors
  18. First trimester tricuspid regurgitation and fetal abnormalities
  19. Gastroschisis: incidence and prediction of growth restriction
  20. Original articles – Newborn
  21. Diminished HLA-DR expression on monocyte and dendritic cell subsets indicating impairment of cellular immunity in pre-term neonates: a prospective observational analysis
  22. First- and fifth-minute Apgar scores of 0–3 and infant mortality: a population-based study in São Paulo State of Brazil
  23. Feeding the feeble: steps towards nourishing preterm infants
  24. Book review
  25. Hot topics in perinatal medicine
  26. Erratum
  27. Erratum to: Impact of the nitric oxide-donor pentaerythrityl-tetranitrate on perinatal outcome in risk pregnancies: a prospective, randomized, double-blinded trial
  28. Congress Calendar
  29. Congress Calendar
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